3. Staphylococcal scalded skin syndrome (SSSS)
Bacterial agent is Staphylococcus aureus
Toxin mediated disease
Person to person transmission
Nikolsky sign positive
Desquamation in 3-5 days
4. Signs & Symptoms
Skin appears burned (scalded)
Other symptoms include malaise,
irritability, fever; nose, mouth and
genitalia may be painful
6. isolation
Fluids:20ml/kg as bolus
Early antibiotics
paracetamol
Tropical wound care –fucidic acid/muprocin
Steroids are avoided ,may worsen immune system
NSAIDS may reduce renal function
Intravenous immunoglobulins for prolonged stay
Removal of dead skin
7.
8. Impetigo (Pyoderma)
Characterized by pus production
Causative agents:
Pyodermic cocci
80% cases caused by S. aureus
Age group:2-6years
Others caused by Streptococcus pyogenes
Group A Streptococcus
Gram-positive coccus, arranged in chains, β-hemolytic
9. Signs & Symptoms
Superficial skin infection
Blisters just below outer skin layer
Blisters replaced by weepy yellow crust
There is little fever or pain
Lymph nodes enlarge near area
May result in erysipelas
Less than 5 years age –fever followed by upper respiratory tract infection ,pharyngitis & conjunctivitis. Positive nikolesky sign
Toxins exfolative /epidrmolytic –causing peeling of outer layer of skin & finally blister formation
CXR to see pneumonia as primary cause of infection
Wound culture from nose /conjectiva/axila
Ten almost always mucous membrane is involved (mouth/conjectiva/trachea/esophagus/anus/vagin
antibiotics-most are resistant to penicillin's –so start pencillin resistant synthetic pencillin –nafcillin/oxacallin & if MARSA is suspected vancomycin/linizolid should be given
Baby recent visit to hospital –initially there was a blister then quickly brusts & leaves a cresty golden patch
Highly contagious spread by direct contact ,minor abrasions predispose to infection
Diagnosis is clinical ,blood cultures are needed somtimes