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Title: Inter-ocular asymmetry of retinal parameters as measured with Ocular
Coherence Tomography (OCT) in a sample of healthy young adults
Zeyad A. Alzaben1
, MSc; Genis Cardona1
, PhD; Miguel A. Zapata2
, MD; Ahmad Zaben3
,
PhD; Miguel José Maldonado López, MD4
; Dana N. Koff, MSc5
.
1
Department of Optometry, Technical University of Catalonia; Terrassa, Spain
2
Department of Ophthalmology, Vall d’Hebron Hospital, Barcelona, Spain
3
Optipunt Eye clinic, Figueres, Spain
4
Department of Ophthalmology, Instituto Oftalmobiologia Aplicada (IOBA);
Valladolid, Spain
5
Allied Medical Sciences Department, Jordan University of Science & Techonology;
Irbid, Jordan
Optical coherence tomography (OCT) is a useful non-invasive technique to assess the retina
without the need for pupil dilation. In particular, the macular and optic disc areas may be explored
in detail and with a high level of spatial resolution. A transversal study was designed in which a
spectral-domain 3D-OCT-2000 (Topcon, Inc., Barcelona, Spain) was employed to evaluate several
retinal parameters in a sample of 37 young Caucasian adults aged between 12 and 23 years
(spherical equivalent from -3.00 to +4.00 D). Normal inter-ocular asymmetry values were
determined and 95% inter-ocular difference tolerance values were obtained. Inter-ocular statistically
significant differences were uncovered in mean and superior RNFL thickness, as well as in central
macular thickness, with larger values in the left eye in all instances, and with tolerance limits of
inter-ocular asymmetry (2.5th
and 97.5th
percentiles) of -9.00 µm to 6.00 µm, -28.00 µm to 9 µm
and -39.00 µm to 29.00 µm, respectively. In addition, statically significant differences were found
between males and females in mean thickness of the retinal nerve fiber layer (RNFL) in the right
eye. These findings give support to the exploration of the normal asymmetries of the retina as an
effective approach for an early detection of pathologies such as glaucoma. Differences in
instrumentation and sample characteristics compromise direct comparison with published research
and warrant the need for further studies.
Biography
Zeyad A. Alzaben received his bachelor degree in Optometry (2013) at the Jordan University of
Science & Technology (JUST), and the first MSc degree in Science of Vision and Optometry
(2014) at the Universitat Politècnica de Catalunya (UPC), and the second MSc degree in Visual
Rehabilitation (2014) at Universida de Valladolid (UVa) / Medicine Faculty, and he is a PhD
candidate in Optical Engineering doctoral program (2014-2016) at Universitat Politècnica de
Catalunya (UPC). He is currently employed as full-time optometrist at the Department of Low
Vision of Optipunt Eye Clinic (www.optipunt.com). He has conducted two new researches about
normal patients and patients affected by pathological myopia using OCT and MAIA
microperimeter, waiting the acceptance letters to be published. Student of Corporate Program for
Management Development / Advanced Program for Optics Management in ESADE Bussines
6th
Global Ophthalmologists Annual Meeting OMICS
School in Barcelona (2014-2017). He is looking for helping people, giving the higher care to the
elder patients, kids and youths. Using his skills to improve his experiences and keep learning more
with respect to the challenges about using his valuable assessments. Making the last aim how could
he improve his substantial life.
Genís Cardona received his degree in Optometry (1992) at the Universitat Politècnica de
Catalunya (UPC), and MSc (1994) and PhD (1996) degrees at the University of Manchester
Institute of Science and Technology (UK). He is currently employed as full-time lecturer at the
Department of Optics and Optometry of the UPC. His research interests include ocular surface and
tear film, contact lenses, refractive surgery, blinking and intraocular lenses.
Miguel A. Zapata received his degree in Medicine / Doctor of Ophthalmology (2001) at the
Universitat Autònoma de Barcelona, and MSc degree in Ophthalmology, and PhD degree to be
specialist in the retina. He was a main researcher in 4 clinical trials (scientific investigations), in 3
basic investigations, and in 7 investigations as coordinator. Membership in RETICS, and an
associated professor in the Universitat Autònoma de Barcelona. Coordinator of OPTretina
(www.optretina.com), 6 years as an administrator of Retinal Department in the Institut
Oftalmologic de Girona, and a consultant ophthalmologist in the Vall d’Hebron Hospital in
Barcelona.
Ahmad Zaben received his bachelor degree in Optometry (1989) at Universitat Politècnica de
Catalunya (UPC), and the first MSc degree in Science of Vision and Optometry (2002) at the
Universitat Politècnica de Catalunya (UPC), and the second MSc degree in Visual Rehabilitation
(2012) at Universida de Valladolid (UVa) / Medicine Faculty, and a PhD degree in Science of
Vision and Optometry (2015) at Universidad Europea de Madrid. He is currently employed as full-
time optometrist at the Department of Low Vision of Optipunt Eye Clinic and a general
administrator (www.optipunt.com). Attented a Corporate Program for Management Development /
Advanced Program for Optics Management in ESADE Bussines School in Barcelona (2011).
Miguel José Maldonado López He is a doctor specialist in Ophthalmology, refractive surgery, and
a group of investigation in visual rehabilitation. MD, PhD, and FEBO. He is an associated professor
in the Universidad de Valladolid (UVa).
Dana N. Koff is a former Optometry lecturer at Jordan University of Science and technology
(JUST) / Irbid where she has been a faculty member for 4.5 years since 2010. She holds a MSc
Degree of optometry from the University of New South Wales (Australia). She conducted a leading
pilot study on the characteristics and short term progression of dry eye disease, and has been held
responsible for establishing a well-equipped Ophthalmic lenses and dispensing lab during her work
in Jordan University of Science and technology in addition to holding a key role as a course
coordinator and student supervisor. She enjoys voluntary community services and participated and
organized free medical days during her work, as well as, with the JUST.
Presenting author details
Full name: Zeyad Abedalmuttaleb Zeyad Alzaben
Contact number: 0034678922564
Twitter account: @zeyadalzaben
Linked In account: https://es.linkedin.com/in/zeyadalzaben
Session name/ number: Track 7 - 3
Category: (Oral presentation/ Poster presentation)

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abstract-zeyad abedalmuttaleb zeyad alzaben

  • 1. Title: Inter-ocular asymmetry of retinal parameters as measured with Ocular Coherence Tomography (OCT) in a sample of healthy young adults Zeyad A. Alzaben1 , MSc; Genis Cardona1 , PhD; Miguel A. Zapata2 , MD; Ahmad Zaben3 , PhD; Miguel José Maldonado López, MD4 ; Dana N. Koff, MSc5 . 1 Department of Optometry, Technical University of Catalonia; Terrassa, Spain 2 Department of Ophthalmology, Vall d’Hebron Hospital, Barcelona, Spain 3 Optipunt Eye clinic, Figueres, Spain 4 Department of Ophthalmology, Instituto Oftalmobiologia Aplicada (IOBA); Valladolid, Spain 5 Allied Medical Sciences Department, Jordan University of Science & Techonology; Irbid, Jordan Optical coherence tomography (OCT) is a useful non-invasive technique to assess the retina without the need for pupil dilation. In particular, the macular and optic disc areas may be explored in detail and with a high level of spatial resolution. A transversal study was designed in which a spectral-domain 3D-OCT-2000 (Topcon, Inc., Barcelona, Spain) was employed to evaluate several retinal parameters in a sample of 37 young Caucasian adults aged between 12 and 23 years (spherical equivalent from -3.00 to +4.00 D). Normal inter-ocular asymmetry values were determined and 95% inter-ocular difference tolerance values were obtained. Inter-ocular statistically significant differences were uncovered in mean and superior RNFL thickness, as well as in central macular thickness, with larger values in the left eye in all instances, and with tolerance limits of inter-ocular asymmetry (2.5th and 97.5th percentiles) of -9.00 µm to 6.00 µm, -28.00 µm to 9 µm and -39.00 µm to 29.00 µm, respectively. In addition, statically significant differences were found between males and females in mean thickness of the retinal nerve fiber layer (RNFL) in the right eye. These findings give support to the exploration of the normal asymmetries of the retina as an effective approach for an early detection of pathologies such as glaucoma. Differences in instrumentation and sample characteristics compromise direct comparison with published research and warrant the need for further studies. Biography Zeyad A. Alzaben received his bachelor degree in Optometry (2013) at the Jordan University of Science & Technology (JUST), and the first MSc degree in Science of Vision and Optometry (2014) at the Universitat Politècnica de Catalunya (UPC), and the second MSc degree in Visual Rehabilitation (2014) at Universida de Valladolid (UVa) / Medicine Faculty, and he is a PhD candidate in Optical Engineering doctoral program (2014-2016) at Universitat Politècnica de Catalunya (UPC). He is currently employed as full-time optometrist at the Department of Low Vision of Optipunt Eye Clinic (www.optipunt.com). He has conducted two new researches about normal patients and patients affected by pathological myopia using OCT and MAIA microperimeter, waiting the acceptance letters to be published. Student of Corporate Program for Management Development / Advanced Program for Optics Management in ESADE Bussines
  • 2. 6th Global Ophthalmologists Annual Meeting OMICS School in Barcelona (2014-2017). He is looking for helping people, giving the higher care to the elder patients, kids and youths. Using his skills to improve his experiences and keep learning more with respect to the challenges about using his valuable assessments. Making the last aim how could he improve his substantial life. Genís Cardona received his degree in Optometry (1992) at the Universitat Politècnica de Catalunya (UPC), and MSc (1994) and PhD (1996) degrees at the University of Manchester Institute of Science and Technology (UK). He is currently employed as full-time lecturer at the Department of Optics and Optometry of the UPC. His research interests include ocular surface and tear film, contact lenses, refractive surgery, blinking and intraocular lenses. Miguel A. Zapata received his degree in Medicine / Doctor of Ophthalmology (2001) at the Universitat Autònoma de Barcelona, and MSc degree in Ophthalmology, and PhD degree to be specialist in the retina. He was a main researcher in 4 clinical trials (scientific investigations), in 3 basic investigations, and in 7 investigations as coordinator. Membership in RETICS, and an associated professor in the Universitat Autònoma de Barcelona. Coordinator of OPTretina (www.optretina.com), 6 years as an administrator of Retinal Department in the Institut Oftalmologic de Girona, and a consultant ophthalmologist in the Vall d’Hebron Hospital in Barcelona. Ahmad Zaben received his bachelor degree in Optometry (1989) at Universitat Politècnica de Catalunya (UPC), and the first MSc degree in Science of Vision and Optometry (2002) at the Universitat Politècnica de Catalunya (UPC), and the second MSc degree in Visual Rehabilitation (2012) at Universida de Valladolid (UVa) / Medicine Faculty, and a PhD degree in Science of Vision and Optometry (2015) at Universidad Europea de Madrid. He is currently employed as full- time optometrist at the Department of Low Vision of Optipunt Eye Clinic and a general administrator (www.optipunt.com). Attented a Corporate Program for Management Development / Advanced Program for Optics Management in ESADE Bussines School in Barcelona (2011). Miguel José Maldonado López He is a doctor specialist in Ophthalmology, refractive surgery, and a group of investigation in visual rehabilitation. MD, PhD, and FEBO. He is an associated professor in the Universidad de Valladolid (UVa). Dana N. Koff is a former Optometry lecturer at Jordan University of Science and technology (JUST) / Irbid where she has been a faculty member for 4.5 years since 2010. She holds a MSc Degree of optometry from the University of New South Wales (Australia). She conducted a leading pilot study on the characteristics and short term progression of dry eye disease, and has been held responsible for establishing a well-equipped Ophthalmic lenses and dispensing lab during her work in Jordan University of Science and technology in addition to holding a key role as a course coordinator and student supervisor. She enjoys voluntary community services and participated and organized free medical days during her work, as well as, with the JUST. Presenting author details Full name: Zeyad Abedalmuttaleb Zeyad Alzaben Contact number: 0034678922564 Twitter account: @zeyadalzaben Linked In account: https://es.linkedin.com/in/zeyadalzaben Session name/ number: Track 7 - 3 Category: (Oral presentation/ Poster presentation)