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ОБЗОР ИНЪЕКЦИОННЫХ ФИЛЛЕРОВ
> Инъекционные anti-age препараты - классификация




                                                    *
> Key market players
  Q-Med (США, Канада):
  •   Первый филлер с НА не животного происхождения
  •   #1 – мировой лидер среди HA дермальных филлеров с Рестилайном,
      старая бифазная технология NASHA с высоким риском покраснения (побочный
      эффект)
  •   Значительная потеря доли рынка после появления Juvederm Ultra
  •   Addition of lidocaine to Restylane and Restylane Perlane for pain management in 2009
  •   “Package offer”: fillers (Restylane, Touch, Perlane, Sub-Q) + rehydration (Vital, Vital Light in
      disposable injector) + injectable breast implants (Macrolane)


  Allergan:
  •   #2 - worldwide market challenger
  •   Acquisition of Inamed – early 2006, Corneal/LEA Derm – end 2006 – building global
      innovative Juvederm brand and positioning Surgiderm as classic Allergan range
  •   Monophasic monodensified technology 3D HA Matrix
  •   Set the trend for lidocaine addition to the filler in 2008
  •   “Package offer”: filler (Juvederm Ultra 2,3,4, Smile, Voluma) + rehydration (Juvederm
      Hydrate) + neurotoxin (Botox) + cosmeuticals + surgical breast implants
> Key market players

   Teoxane:
   •   Very aggressive worldwide pricing (no R&D cost of advanced technology)
   •   Generic monophasic monodensified technology
   •   “Cleaned-up” Pure Sense fillers range with fewer products (from 6 + 1 to 5 + 1), the
       addition of lidocaine for pain management in 2010
   •   Big range – mostly repackaging for segmentation
   •   “Package offer”: fillers (Teosyal Pure Sense First Lines, Global Action, Deep Lines,
       Kiss, Ultra Deep, Teosyal Ultimate) + rehydration (Teosyal Meso) + cosmeuticals



   Filorga:
   •   Strong development of registered rejuvenation products with diverse vitamin cocktails
       at an attractive price - NCTF 135 and 135 HA (54 + 1 ingredient: 13 vitamins, 23
       amino acids, 6 minerals, 6 coenzymes, 5 nucleic acids, 2 reducing agents, HA)
   •   Generic monophasic monodensified technology
   •   “Package offer”: fillers(X-HA³, X-HA Volume) + mesotherapy cocktails (NCTF 135 and
       135 HA) + rehydration (M-HA 18 with glycerol) + glycopeels + creams
> Key market players
  Croma:
  •   New HA-based product range (2009)
  •   S.m.a.r.t. technology (supreme monophasic and reticulated technology) - monodensified
  •   Addition of glycerol to facial rehydration product Princess Rich (copied by Croma’s private
      labels Hualuronica Mesolift and Genyal Genyalift)
  •   “Package offer”: filler (Princess Filler, Volume) + rehydration (Rich )
  Vivacy:
  •   New filler range (2008) with the addition of antioxidant – mannitol
  •   In 2010 addition of lidocaine into Stylage M and Stylage Special Lips
  •   IPN-Like technology (inter-penetrated networks) – monophasic monodensified
  •   “Package offer”: filler (Stylage Special Lips, Stylage S, M, L, XL) + rehydration (Stylage
      Hydro+manni tol, Stylage Hydro Max+sorbitol)


  Pierre Fabre:
  •   Leader in pharmaceutical dermo-cosmetics in France (#2 in Europe)
  •   New filler range (2008) with the addition of antioxidant – mannitol, monophasic
      monodensified technology
  •   “Package offer”: filler (Glyton 2,3,4) + chemical peels + creams
> Key market players
 Merz Aesthetics:
 •   Anteis exclusive licensing partner – Belotero is a private label of Esthélis for Austria,
     Germany, Italy, Russia, Switzerland, UK and US
 •   Technology: Belotero – CPM (monophasic polydensified)
 •   “Package offer”: fillers (biodegradable - Belotero Soft, Basic (Balance), Intense; semi
     biodegradable - Radiesse) + rehydration (Hyal-System) + neurotoxin (Bocouture, previously
     Xeomin)



 Galderma:
 •   One of the world's leading dermatology companies founded as a joint venture between Nestlé
     and L'Oréal. Entered aesthetic market at the end of 2010 with the launch of Emervel
 •   Technology: Optimal Balance Technology - monophasic monodensified with lidocaine
 •   “Package offer”: filler (Emervel Touch, Classic, Deep, Lips, Volume)
> Key market players
 Anteis:
 •   Industry's most awarded company for innovation and technology
 •   Technology: dynamic cross-linking process resulting in monophasic polydensified technology
     with tissue adapted characteristics CPM (Cohesive Polydensified Matrix), EVE (Extra
     Volumizing Elasticity), HPM (Hybrid Plastic Matrix) - latest and safest on the market, most
     natural-looking results (bio-integration)
 •   Rehydration technology: patented combination of HA + glycerol (Mesolis+)
 •   Jolidermis fillers are positioned as classic Anteis range
 •   “Package offer”: filler (Esthélis Soft, Esthélis Soft+Glycerol, Esthélis Basic, Esthélis Basic
     +Glycerol, Fortélis, Modelis,Jolidermis (Merz countries) ) + rehydration (Mesolis/Mesolis+)
 •   Unique service for the practitioner - Anteis Injection System

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обзор инъекционных филеров

  • 2. > Инъекционные anti-age препараты - классификация *
  • 3. > Key market players Q-Med (США, Канада): • Первый филлер с НА не животного происхождения • #1 – мировой лидер среди HA дермальных филлеров с Рестилайном, старая бифазная технология NASHA с высоким риском покраснения (побочный эффект) • Значительная потеря доли рынка после появления Juvederm Ultra • Addition of lidocaine to Restylane and Restylane Perlane for pain management in 2009 • “Package offer”: fillers (Restylane, Touch, Perlane, Sub-Q) + rehydration (Vital, Vital Light in disposable injector) + injectable breast implants (Macrolane) Allergan: • #2 - worldwide market challenger • Acquisition of Inamed – early 2006, Corneal/LEA Derm – end 2006 – building global innovative Juvederm brand and positioning Surgiderm as classic Allergan range • Monophasic monodensified technology 3D HA Matrix • Set the trend for lidocaine addition to the filler in 2008 • “Package offer”: filler (Juvederm Ultra 2,3,4, Smile, Voluma) + rehydration (Juvederm Hydrate) + neurotoxin (Botox) + cosmeuticals + surgical breast implants
  • 4. > Key market players Teoxane: • Very aggressive worldwide pricing (no R&D cost of advanced technology) • Generic monophasic monodensified technology • “Cleaned-up” Pure Sense fillers range with fewer products (from 6 + 1 to 5 + 1), the addition of lidocaine for pain management in 2010 • Big range – mostly repackaging for segmentation • “Package offer”: fillers (Teosyal Pure Sense First Lines, Global Action, Deep Lines, Kiss, Ultra Deep, Teosyal Ultimate) + rehydration (Teosyal Meso) + cosmeuticals Filorga: • Strong development of registered rejuvenation products with diverse vitamin cocktails at an attractive price - NCTF 135 and 135 HA (54 + 1 ingredient: 13 vitamins, 23 amino acids, 6 minerals, 6 coenzymes, 5 nucleic acids, 2 reducing agents, HA) • Generic monophasic monodensified technology • “Package offer”: fillers(X-HA³, X-HA Volume) + mesotherapy cocktails (NCTF 135 and 135 HA) + rehydration (M-HA 18 with glycerol) + glycopeels + creams
  • 5. > Key market players Croma: • New HA-based product range (2009) • S.m.a.r.t. technology (supreme monophasic and reticulated technology) - monodensified • Addition of glycerol to facial rehydration product Princess Rich (copied by Croma’s private labels Hualuronica Mesolift and Genyal Genyalift) • “Package offer”: filler (Princess Filler, Volume) + rehydration (Rich ) Vivacy: • New filler range (2008) with the addition of antioxidant – mannitol • In 2010 addition of lidocaine into Stylage M and Stylage Special Lips • IPN-Like technology (inter-penetrated networks) – monophasic monodensified • “Package offer”: filler (Stylage Special Lips, Stylage S, M, L, XL) + rehydration (Stylage Hydro+manni tol, Stylage Hydro Max+sorbitol) Pierre Fabre: • Leader in pharmaceutical dermo-cosmetics in France (#2 in Europe) • New filler range (2008) with the addition of antioxidant – mannitol, monophasic monodensified technology • “Package offer”: filler (Glyton 2,3,4) + chemical peels + creams
  • 6. > Key market players Merz Aesthetics: • Anteis exclusive licensing partner – Belotero is a private label of Esthélis for Austria, Germany, Italy, Russia, Switzerland, UK and US • Technology: Belotero – CPM (monophasic polydensified) • “Package offer”: fillers (biodegradable - Belotero Soft, Basic (Balance), Intense; semi biodegradable - Radiesse) + rehydration (Hyal-System) + neurotoxin (Bocouture, previously Xeomin) Galderma: • One of the world's leading dermatology companies founded as a joint venture between Nestlé and L'Oréal. Entered aesthetic market at the end of 2010 with the launch of Emervel • Technology: Optimal Balance Technology - monophasic monodensified with lidocaine • “Package offer”: filler (Emervel Touch, Classic, Deep, Lips, Volume)
  • 7. > Key market players Anteis: • Industry's most awarded company for innovation and technology • Technology: dynamic cross-linking process resulting in monophasic polydensified technology with tissue adapted characteristics CPM (Cohesive Polydensified Matrix), EVE (Extra Volumizing Elasticity), HPM (Hybrid Plastic Matrix) - latest and safest on the market, most natural-looking results (bio-integration) • Rehydration technology: patented combination of HA + glycerol (Mesolis+) • Jolidermis fillers are positioned as classic Anteis range • “Package offer”: filler (Esthélis Soft, Esthélis Soft+Glycerol, Esthélis Basic, Esthélis Basic +Glycerol, Fortélis, Modelis,Jolidermis (Merz countries) ) + rehydration (Mesolis/Mesolis+) • Unique service for the practitioner - Anteis Injection System