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From Technologies to Market
Chinese Microfluidics
Industry
2018 Report
Sample
© 2018
2
3M, Abaxis, Abbott, Affymetrix, Agilent Technologies, Alere,Anatech, BaiCare, BD, Beijing Bohui Innovation Technologies, Beijing e-
science, Beijing Genomics Institute (BGI Shenzhen), Beijing Unibio, Beijing University of Technology, Berry Genomics, Biocartis,
bioMérieux, Caliper Life Sciences (PerkinElmer), CapitalBio, Celsee, Cepheid, Chinese Academy of Sciences, Chongqing
University, Clearbridge Biomedics, CNRS, Corning, Coyote Biosciences, Dalian Institute of Chemical Physics, Dalian University of
Technology, Daohui Biotech, Denz Bio-Medical, Digital Biosystems, Dolomite, Each-reach (Rongzhi Biotech), Elveflow, Excbio,
Fapon, Fluidigm, Fluigent, Foxgene, Fudan University, Funai Electric, Genetel Pharmaceuticals, Getein Biotech, Guangzhou Sio
Optics, Harbin Institute of Technology, Harvard College, HealthDigit, Heto, Hicomp Microtech, Highland Best, Hochuen,
Honeywell, HP, Huakairui, IBM, Illumina, Institute of High Energy Physics, Inzign, Jiangsu University, JIER Machine Tool Group,
LabSmith, Lianer Technology, Little Things Factory, Maccura, Mesosbiosys, Micronit, Micropoint Biosciences, Micrux Technologies,
Mindray, MiTASChip, MNChip, Nanoctr, NanoEntek, NanoLite Systems, Nanomed Skincare, Oxford Nanopore Technologies,
Pacific Biosciences, Peking University, Philips, Prinzen Bio (Shanghai Yanzan Biotechnology), Purui Kang, PushKang Biotechnology,
Qiagen, Quanterix, Quidel, Ray Biotech, Rayme Biotech, Renji Hospital, Robert Bosch, Roche, Samsung Electronics, Schott,
Sensilicon (Shanghai Central Core Electronics), Shanghai Baio Technology, Shanghai Biochip, Shanghai Biotechnology Corporation,
Shanghai Hengxin Biotechnology, Shanghai Industrial µTechnology Research Institute (SITRI), Shanghai Jiao Tong University,
Shenyang Machine Tool, SIASUN Robot & Automation, Silex Microsystems, Sinochips, Solvay, Sony, Southeast University,
Superchip Technology, Suzhou Genso Optoelectronic Technology, Suzhou Hailu Biotech (Halo),Tecnisco,Thermo Fisher Scientific,
Tianjin Biochip,Tinker Bio,Tongfang Biochip,Tsinghua University, University of California,Watmind,Wenchang Chip,Wenhao Chip,
Yaneng Bio,Yulong Biomedical, Zhejiang University…
… and more!
LIST OF COMPANIES MENTIONED IN THIS REPORT
170+ slides of market and technology analysis
Information gathered through direct discussions with players all along the supply chain
©2018 | www.yole.fr | Chinese Microfluidics Industry | Sample
3
Biography & contact
ABOUTTHE AUTHORS
Sébastien Clerc
Sébastien Clerc works as a Medical Technologies & Market Analyst at Yole Développement (Yole). As part of the Medical
Technologies (MedTech) business unit, Sébastien has authored a collection of market and technology reports dedicated to
topics such as microfluidics, point-of-care, MEMS for healthcare applications, and connected medical devices. In parallel, he is
regularly involved in custom projects including strategic marketing, technology scouting, and technology evaluation, designed to
help academic and industrial players in their innovation processes. Leveraging his technology and market expertise, Sébastien
has spoken at more than 10 industry conferences worldwide in the last two years.
Sébastien graduated from Grenoble Institute of Technology (Grenoble INP - Grenoble, France) with a master’s degree in
Biomedical Technologies. He then completed his cursus with a master’s degree in Innovation and Technology Management from
the same institute.
Email: clerc@yole.fr
Hong LIN
Dr. Hong Lin works at Yole Développement (Yole), as a Technology and Market Analyst, Compound Semiconductors within the
Power & Wireless division since 2013. She is specialized in compound semiconductors and provides technical and economic
analysis. Before joining Yole Développement, she worked as R&D engineer at Newstep Technologies. She was in charge of the
development of cold cathodes by PECVD for visible and UV lamp applications based on nanotechnologies. She holds a Ph.D in
Physics and Chemistry of materials.
Email: lin@yole.fr
4
OBJECTIVES OF THE REPORT
• Identify microfluidics applications in China and understand the associated ecosystem
• Identify the local technologies and understand their ability to answer market needs
• Provide a mapping of the players at each level of the supply chain
• Explain how the Chinese players compare to western players in terms of expertise, know-how and capabilities, how they are working
together, and understand if there is a threat for western players
• Understand how this ecosystem may evolve
• Provide market data 2016 and 2017 and provide forecasts 2017 – 2023
• Provide a brief overview of the microfluidic Intellectual Property landscape in China
• Provide company profiles of all the identified Chinese players
• Obtain a global vision of the Chinese microfluidic market, taking into account real industrial concerns, along the whole supply chain, and
considering both Chinese and foreign players
5
TABLE OF CONTENTS (1/2)
Executive Summary p.10
Landscape overview p.40
Definitions and introduction
Mapping of Chinese microfluidic players
Market landscape
Funding model
Comparison between China and other countries
China’s strengths
Why is the government supporting microfluidics?
Poor ecosystem for system development
Drivers for microfluidics adoption in China
Chinese companies starting business abroad
Conclusions
Patent analysis p.67
Market data and forecasts p.84
Microfluidic-based products (volume)
Microfluidic-based products (value)
Microfluidic-based products: market share
Microfluidic devices (value)
Microfluidic-based products: value of the chip
Microfluidic devices: market share of Chinese fabs
What tomorrow could look like
Several applications, different dynamics p.94
Applications & dynamics
Pharma chips production
NGS in China: market share, BGI strategy
Some applications/technologies are expected to grow rapidly
Foreign microfluidic companies in China
Conclusions
6
TABLE OF CONTENTS (2/2)
Supply chain and value chain p.108
Introduction
Microfluidic cartridge production: different models
Repartition of Chinese players per type of company
Microfluidic chip processing equipment
Materials
Players capabilities
Examples of production collaborations
Foreign players in China
Distributors for western players
Other examples of collaboration
How do fabs position?
Technical capabilities
Chinese players working for western companies
Demand for glass microfluidics
Reagent deposition capabilities
Interactions between world regions
Criteria for selecting a development and industrialization partner
Value chain for point-of-need applications
Conclusions
Examples of products & company profiles
p.133
Regulatory & market access p.168
Report conclusion p.177
7
SCOPE OF THE REPORT
This report aims to explain the status of the
microfluidics industry in Mainland China (Taiwan
and Hong-Kong are thus not included).
It covers:
- Chinese microfluidic players having
activities in China and abroad
- Foreign microfluidic players having
activities in China
Hong Kong
Taiwan
8
INTRODUCTION
Definition: our vision of microfluidics
What do we
consider as
microfluidics?
• Microfluidics is the science and technology that deals with the manipulation of fluids usually in the range of
microliters (10-6) to picoliters (10-12) and/or in networks of micrometer-size channels.
• Our definition of microfluidics encompass:
Active fluid management
techniques for very small volumes
Micro-fabricated devices with
channels below ~500µm in size
And/or
9
INTRODUCTION
Our vision of the microfluidics market
• We divided these technologies in 2 components in order to better explain the microfluidics market:
• Microfluidic device:
• The microfluidic device is defined as the microfluidic technology manufactured. It can be a chip, a cartridge, a dispensing
tool, a flow control component and other types of microfluidic components.
• The microfluidic chips represent 85% of the market of the microfluidic device.
• Microfluidic product:
• The microfluidic product is defined as the microfluidic device packaged for sale for the end-user.
• The reagents are added to the device to create the product if needed.
• For example in point-of-care applications the microfluidic product is a microfluidic device where reagents are added, one
test corresponds to one microfluidic cartridge (even if it is sometimes possible to make several analysis on the product
(multiplexing).
• Example of the AlereTriage method Alere Triage® MeterPro
Source: Alere
Microfluidic device:
chip
Microfluidic product:
cartridge packaged with
reagents
Alere Triage® Cardiac Panel
Source:Alere
Microfluidic analyzer
Not taken into
account in the
market analysis
Most
microfluidic
devices are chips.
When combined
with biological
content, these
chips become
products
10
MICROFLUIDIC APPLICATIONS DEFINITION
Microfluidic
technology is used
everywhere
Microfluidic
Applications
Clinical &
Veterinary
Diagnostics
Point of
Care
Diagnostics
Pharma &
Life Sciences
Research
Analytical
Devices
Industrial,
Environmental
& Agro-Food
Drug
Delivery
Micro
Reaction -
Flow
Chemistry
• Clinical and Veterinary Diagnostics
Laboratory equipment for clinical and veterinary
diagnostics
• Point-of-Care Diagnostics
Out-of-the-lab diagnostic equipment for near-patient
testing, intensive care, doctor’s offices, home testing
• Pharmaceutical and Life Science Research
Microfluidic devices for drug discovery and screening,
genomics, proteomics, cell analysis…
• Analytical Devices
Microfluidic chips and columns for mass spectrometry,
chromatography and HPLC sample preparation
• Industrial, Environmental and Agro-FoodTesting
Microfluidic-based tests for quality/process control and
water testing (pesticides, bacteria, etc.). Includes
military, security and forensics applications
• Drug delivery
Microfluidic devices for drug delivery, such as inhalers,
microneedles and implantable micropumps
• Micro Reaction – Flow Chemistry
Microfluidic devices for micro reaction involved in
research or in pilot-production units
11
CHINESE MICROFLUIDIC LANDSCAPE: INTRODUCTION
• In recent years, China has become very active in point of care, high-throughput sequencing and other medical
diagnostics. In 2014, 229 Chinese companies active in microfluidics were identified*. We believe this number has
exploded in the past few years thanks to the government’s policy wanting to ensure a strong position of China in
this field, the availability of local inexpensive manufacturing technologies and the creation of many spin off
companies from research institutes.
• Indeed, the Chinese government has set up a strategic plan to comprehensively upgrade the Chinese industry and
make the country a major player, independent from other countries. This plan, named Made in China 2025,
includes a focus on pharmaceuticals and medical devices. Companies involved in these sectors will benefit from
almost unlimited funding by 2025 to catch up with foreign industries and take back significant market share in
China. As a key tool for diagnostics and life sciences applications, microfluidic technology will for sure benefit of
money spend in the context of this strategic plan.
• *Source: MinacNed
12
CONTENT OF THE REPORT
Chinese microfluidic landscape description
13
CONTENT OF THE REPORT
Patent analysis
14
CONTENT OF THE REPORT
Market data and forecasts
15
CONTENT OF THE REPORT
Description of microfluidic applications in China
16
CONTENT OF THE REPORT
Supply and value chain analysis (1/2)
17
CONTENT OF THE REPORT
Supply and value chain analysis (2/2)
18
CONTENT OF THE REPORT
Company profiles and examples of products
19
RELATED REPORTS
The Chinese government has created a strategic
plan to comprehensively upgrade the country’s
industrial sector and make China a major player
that is independent from other countries. This
plan, “Made in China 2025”, includes a focus on
pharmaceuticals and medical devices. Companies
involved in these sectors will benefit from almost
unlimited funding by 2025, with the goal to compete
with foreign industries and retake significant
market share.
As a key tool for diagnostics and life sciences
applications, microfluidic technology will surely
benefit from this massive spend. Indeed, the chinese
diagnostics market is currently dominated by large
international companies like Roche and Abbott, but
new Chinese companies are rising up to compete
with them. The opportunity is huge for these
emerging Chinese players, because the current
domination of foreign players results in products
that are considered too expensive and often way
beyond reimbursement thresholds. Thus, Chinese
players able to propose similar solutions at a lower
price will seriously threaten these giants’ position
in the Chinese market. We are not there yet
because performance and quality still don’t meet
the expectations, but the path to 2025 is long and
China’s industry is improving rapidly. Moreover,
demand is growing quickly: indeed, China already
hastheworld’slargestpopulation,onewhichisaging
rapidly and thus needs improved care. Additionally,
the end of the “one-child policy” has resulted in
numerous births and an increased demand in areas
such as non-invasive prenatal testing.
For all these reasons, the Chinese microfluidic
market will be strongly impacted. Yole
Développement (Yole)’s analysts expect that the
market for microfluidic-based products sold by
Chinese players will grow at a CAGR2017-2023
of 28%,
from $171M in 2017 to $754.1M in 2023.
CHINESE MICROFLUIDICS INDUSTRY 2018
Market & Technology report - July 2018
WITH AN EYE TOWARDS 2025, CHINA HAS LAUNCHED A DEEP
TRANSFORMATION OF ITS INDUSTRIAL SECTOR
Will the Chinese microfluidics industry change the worldwide microfluidic landscape?
KEY FEATURES
•	Mapping of Chinese microfluidic
players
•	Analysis of both local and foreign
players’ sales and positioning in
China
•	Market landscape overview
•	Comparison between China and
other countries
•	Drivers for microfluidics adoption
in China
•	Market data and forecasts 2017 -
2023 for microfluidic-based
products and for microfluidic
devices, in volume (units) and in
value ($M)
•	Analysis of the dynamic
applications, with a focus on next-
generation sequencing
•	Supply and value chain analysis,
with overview of Chinese players’
capabilities and limitations
•	Company profiles
•	First-level patent analysis
•	First-level regulatory and market
access information
(Yole Développement, July 2018)
Tianjin
Beijing
Hangzhou
Wuhan
(Each-reach)
Chengdu Suzhou Shanghai
Shenzhen
*Non-exhaustive list of companies
THE CHINESE MICROFLUIDICS INDUSTRY: A FAST-MOVING ECOSYSTEM
As a consequence of governmental support,
numerous Chinese companies were recently spun-
off from several universities. Starting from 2002,
Government funding for microfluidic research
and microfluidic companies has reached several
tens of millions yuan per year, with a significant
explosion in recent years. The government is also
recalling Chinese executives and engineers who
have worked overseas for years in order to lead
these new Chinese companies and increase their
chances of success. Market demand is growing,
and students in microfluidics are being recruited
before they even graduate.
Yole has identified 40+ Chinese companies
involved in microfluidic device manufacturing
2018 - Mapping of Chinese microfluidic players*
CHINESE MICROFLUIDICS INDUSTRY 2018
CHINESE MICROFLUIDIC COMPANIES: A THREAT TO FOREIGN PLAYERS?
Among the Chinese companies that look promising,
Bohui and Micropoint are two which have full
capabilities for manufacturing their microfluidic-based
products, and their position is clearly to propose
alternatives to the diagnostic products sold by
international giants. Such companies are growing well
and finding success by proposing similar solutions to
the international giants, but at a much lower price.
Thanks to this strategy, some Chinese companies are
beginning to attract foreign customers who cannot
afford similar services at Western prices. Currently,
quality is still inferior to what foreign companies can
offer, but this could significantly change over the next
5 - 10 years.
Globally, this is the strategy of most Chinese
microfluidic players, at all levels of the supply chain:
propose “good enough” products or services at a
low cost, gain contracts, and grow quickly. The most
obvious example is that of BGI. The genomics company
has released DNA sequencers over the past three
years, first in China and now worldwide. Though BGI’s
technology is said to still trail the field’s gold standard
(i.e. Illumina), its aggressive pricing policy allows it to
rapidly gain market share and make significant progress
in terms of performance. Interestingly, numerous
people share the same opinion: “BGI will kill Illumina”.
It may be too early to make such a bold statement, but
one thing is sure: certain Chinese companies have the
potential to be a real threat to Western players, which
must find solutions to contest these Asian newcomers
in their respective markets, at all levels of the supply
chain.
This report details the current capabilities of more
than 25 Chinese microfluidic players and furnishes 30+
company profiles detailing who these players are.
and/or integration. Though a few companies (i.e.
CapitalBio) have existed since the 2000s, most of
these microfluidic companies have been around only
a few years, and some of them already have products
on the market. In fact, the timeline from company
inception to product commercialization seems much
shorter in China than abroad.
Today, the Chinese supply chain’s maturity is
similar to what Europe and the USA’s supply chain
resembled ten years ago: very few companies have
full capabilities (from design and prototyping to mass
manufacturing and back-end processing), and only
a few projects reach mass production. However,
China’s evolution should be much faster, and it won’t
take the Chinese industry 10 years to catch up. The
questions are: “What will be the first significant
commercial success?” and “Who will be the Chinese
versions of Cepheid and Abaxis, two American
diagnostic companies that in the 2000s found success
with microfluidic technology and were recently
acquired by diagnostic giants?”
In this report, Yole’s analysts explain how China’s
ecosystem may evolve over the next few years,
whether foreign players can survive, and how some
Chinese players are destined for big things.
How the Chinese microfluidic landscape could appear in a few years*
(Yole Développement, July 2018)
Microfluidics-
based revenue
Chinese
companies
Foreign
companies
Several international
giants with decreasing
market share
Numerous small
Chinese players with
medium revenue / low
market share
Few foreign players
(decreasing number)
with low revenue /
market share
Several Chinese
giants
*Non-exhaustive list of companies
Next-generation sequencing market share in China: what could happen by 2025?
(Yole Développement, July 2018)
67%
57%
Year 2017
US$ 379 MILLION
9%
12%
US$ 1,854 MILLION
13%
8%
24%
8%
Others
 1%
Others
2 %
CAGR2017-2025
: 22%
And more…
Year 2025
MARKET  TECHNOLOGY REPORT
COMPANIES CITED IN THE REPORT (non exhaustive list)
3M, Abaxis, Abbott, Affymetrix, Agilent Technologies, Alere, Anatech, BaiCare, BD, Beijing Bohui
InnovationTechnologies,Beijinge-science,BeijingGenomicsInstitute(BGIShenzhen),BeijingUnibio,Beijing
University of Technology, Berry Genomics, Biocartis, bioMérieux, Caliper Life Sciences (PerkinElmer),
CapitalBio, Celsee, Cepheid, Chinese Academy of Sciences, Chongqing University, Clearbridge Biomedics,
CNRS, Corning, Coyote Biosciences, Dalian Institute of Chemical Physics, Dalian University of Technology,
Daohui Biotech, Denz Bio-Medical, Digital Biosystems, Dolomite, Each-reach (Rongzhi Biotech), Elveflow,
Excbio, Fapon, Fluidigm, Fluigent, Foxgene, Fudan University, Funai Electric, Genetel Pharmaceuticals,
Getein Biotech, Guangzhou Sio Optics, Harbin Institute of Technology, Harvard College, HealthDigit,
Heto, Hicomp Microtech, Highland Best, Hochuen, Honeywell, HP, Huakairui, IBM, Illumina, Institute of
High Energy Physics, Inzign, Jiangsu University, JIER Machine Tool Group, LabSmith, Lianer Technology,
Little Things Factory, Maccura, Mesosbiosys, Micronit, Micropoint Biosciences, Micrux Technologies,
Mindray, MiTASChip, MNChip, Nanoctr, NanoEntek, NanoLite Systems, Nanomed Skincare, Oxford
Nanopore Technologies, Pacific Biosciences, Peking University, Philips, Prinzen Bio (Shanghai Yanzan
Biotechnology), Purui Kang, PushKang Biotechnology, Qiagen, Quanterix, Quidel, Ray Biotech, Rayme
Biotech, Renji Hospital, Robert Bosch, Roche, Samsung Electronics, Schott, Sensilicon (Shanghai Central
Core Electronics), Shanghai Baio Technology, Shanghai Biochip, Shanghai Biotechnology Corporation,
Shanghai Hengxin Biotechnology, Shanghai Industrial µTechnology Research Institute (SITRI), Shanghai Jiao
Tong University, Shenyang Machine Tool, SIASUN Robot  Automation, Silex Microsystems, Sinochips,
Solvay, Sony, Southeast University, Superchip Technology, Suzhou Genso Optoelectronic Technology,
Suzhou Hailu Biotech (Halo), Tecnisco, Thermo Fisher Scientific, Tianjin Biochip, Tinker Bio, Tongfang
Biochip, Tsinghua University, University of California, Watmind, Wenchang Chip, Wenhao Chip, Yaneng
Bio, Yulong Biomedical, Zhejiang University, and more...

Executive Summary 	 10
Landscape overview 	 40
 Definitions and introduction
 Mapping of Chinese microfluidic players
 Market landscape
 Funding model
 Comparison between China and other countries
 China’s strengths
 Why is the Chinese government supporting
microfluidics?
 Poor ecosystem for system development
 Drivers for microfluidics adoption in China
 Chinese companies starting businesses abroad
 Conclusions
Patent analysis 	 67
Market data and forecasts 	 84
 Microfluidic-based products (volume)
 Microfluidic-based products (value)
 Microfluidic-based products - market share
 Microfluidic devices (value)
 Microfluidic-based products - chip value
 Microfluidic devices - Chinese foundries’ market
share
 What tomorrow could look like
Several applications, different dynamics	 94
 Applications  dynamics
 Pharma chip production
 NGS in China - market share, BGI strategy
 Some applications/technologies are expected to
grow rapidly
 Foreign microfluidic companies in China
 Conclusions
Supply chain and value chain 	 108
 Introduction
 Microfluidic cartridge production - different models
 Repartition of Chinese players, per company type
 Microfluidic chip processing equipment
 Materials
 Players’ capabilities
 Examples of production collaborations
 Foreign players in China
 Distributors for Western players
 Other collaboration examples
 How do foundries position?
 Technical capabilities
 Chinese players working for Western companies
 Glass microfluidics - demand
 Reagent deposition capabilities
 Interactions between world regions
 Criteria for selecting a development and
industrialization partner
 Value chain for point-of-need applications
 Conclusions
Examples of products and company profiles 	 133
Regulatory and market access 	 168
Report conclusion 	 177
TABLE OF CONTENTS (complete content on i-Micronews.com)
OBJECTIVES OF THE REPORT
•	 Publish a global vision of the Chinese microfluidic market, taking into account real industrial
concerns along the whole supply chain, and considering Chinese and foreign players
•	 Identify microfluidics applications in China and understand the associated ecosystem
•	 Identify the local technologies and understand their ability to answer market needs
•	 Map players at each level of the supply chain
•	 Explain how Chinese players compare to Western players in terms of expertise, know-how,  
capabilities, and how they work together, and understand whether they can threaten Western
players
•	 Examine how this ecosystem might evolve
•	 Provide 2016 - 2017 market data and furnish forecasts for 2017 - 2023
•	 Deliver a brief overview of China’s microfluidic IP landscape
•	 Provide company profiles for all identified Chinese players
AUTHORS
Sébastien Clerc worksasaTechnologies
 Market Analyst, Microfluidics  Medical
Technologies at Yole Développement
(Yole). Sébastien authored a collection of
market and technology reports dedicated
to topics such as microfluidics, point-of-care
and more. In parallel, he is daily involved in
custom projects. Thanks to its technology
 market expertise, Sébastien has spoken
in more than 10 industry conferences
worldwide over the last 2 years. Sébastien
Clerc is graduated from Grenoble Institute
of Technology (Grenoble INP - Grenoble,
France) with a Master degree in Biomedical
Technologies. Then he completed his cursus
with a Master degree in Innovation and
TechnologyManagementinthesameinstitute.
Find more
details about
this report here:
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Dr.HongLinworksatYoleDéveloppement
(Yole), as a Technology and Market Analyst,
Compound Semiconductors within the
Power  Wireless division since 2013. She
is specialized in compound semiconductors
and provides technical and economic
analysis.BeforejoiningYoleDéveloppement,
she worked as RD engineer at Newstep
Technologies. She was in charge of the
development of cold cathodes by PECVD
for visible and UV lamp applications based
on nanotechnologies. She holds a Ph.D in
Physics and Chemistry of materials.
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From Technologies to Market
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o BioMEMS
o Inkjet Printing
o Solid-State Medical Imaging BioPhotonics
o BioTechnologies
Power
Wireless
o RF DevicesTechnology
o Compound Semiconductors Emerging Materials
o Power Electronics
o Batteries  Energy Management
Semiconductor
 Software
o Package Assembly  Substrates
o SemiconductorManufacturing
o Memory
o Software  Computing
Photonics,
Sensing  Display
o Solid-State Lighting  Display
o MEMS,Sensors  Actuators
o Imaging
o Photonics  Optoelectronics
Semiconductor
 Software
Power  Wireless
Photonics,
Sensing
 Display
Life
Sciences 
Healthcare
3©2018 | www.yole.fr | About Yole Développement
3 BUSINESS MODELS
o Consulting and Analysis
• Market data  research,
marketing analysis
• Technology analysis
• Strategy consulting
• Reverse engineering  costing
• Patent analysis
• Design and characterization of
innovative optical systems
• Financial services (due diligence,
MA with our partner)
www.yole.fr
o Syndicated reports
• Market  technology reports
• Patent investigation and patent
infringement risk analysis
• Teardowns  reverse costing
analysis
• Cost simulation tool
www.i-Micronews.com/reports
o Media
• i-Micronews.com website
• @Micronews e-newsletter
• Communication  webcast
services
• Events:TechDays,forums,…
www.i-Micronews.com
4©2018 | www.yole.fr | About Yole Développement
6 COMPANIES TO SERVEYOUR BUSINESS
Due diligence
www.yole.fr
Manufacturing costs analysis
Teardown and reverse engineering
Cost simulation tools
www.systemplus.fr
Market,technology and strategy
consulting
www.yole.fr
IP analysis
Patent assessment
www.knowmade.fr
Innovation and business maker
www.bmorpho.com
Design and characterization of
innovative optical systems
www.piseo.fr
Yole Group of Companies
5©2018 | www.yole.fr | About Yole Développement
OUR GLOBAL ACTIVITY
30%of our business
40%of our business
30%of our business
Greater
China office
Yole Japan
HQ in Lyon
Nantes
Paris
Nice
Vénissieux
Europe office
Frankfurt
Hsinchu
Tokyo
Yole Inc.
Phoenix
Yole Korea
Seoul
Palo Alto
6©2018 | www.yole.fr | About Yole Développement
ANALYSIS SERVICES - CONTENT COMPARISON
Technology
and Market
Report
Leadership
Meeting
QA
Service
Depth of the analysis
Breadthoftheanalysis
Meet the
Analyst
Custom
Analysis
High
High
Low
7©2018 | www.yole.fr | About Yole Développement
SERVINGTHE ENTIRE SUPPLY CHAIN
Our analysts
provide
market
analysis,
technology
evaluation,
and business
plans along
the entire
supply chain
Integrators,end-
users and software
developpers
Device manufacturers
Suppliers:material,equipment,
OSAT,foundries…
Financial investors,RD centers
8©2018 | www.yole.fr | About Yole Développement
SERVING MULTIPLE INDUSTRIAL FIELDS
We work
across
multiples
industries to
understand
the impact of
More-than-
Moore
technologies
from device
to system
FromA to Z…
Transportation
makers
Mobile phone
and
consumer
electronics
Automotive
Medical
systems
Industrial
and defense
Energy
management
9©2018 | www.yole.fr | About Yole Développement
o Yole Développement, System Plus Consulting, KnowMade and PISEO, all part of Yole Group of Companies, keep on increasing their collaboration to offer, in 2018, a
collection of 150+ reports. Combining respective expertise and methodologies from the 4 companies, the reports aim to provide market  technology analysis, patent
investigation and patent infringement risk analysis, teardowns  reverse costing analysis.They cover:
o You are looking for:
• An analysis of your product market
• A review of your competitors evolution
• An understanding of your manufacturing and production costs
• An understanding of your industry technology roadmap and related IPs
• A clear view on the evolution of the supply chain…
Our reports are for you!
The combined team of 60+ experts (PhDs, MBAs, industry veterans…) from Yole Développement, System Plus Consulting, KnowMade and PISEO, collect information,
identify the trends, the challenges, the emerging markets, the competitive environments and turn it into results to give you a complete picture of your industry
landscape.
In the past 20 years, we worked on more than 1 700 projects, interacting with technology professionals and high level opinion makers from the main players of the
industry.
o In 2018, Yole Group of Companies plan to publish +150 reports.Gain full benefit from our Bundled Offer and receive at least a 36% discount.
REPORTS COLLECTION
www.i-Micronews.com
• MEMS  Sensors
• RF devices  technologies
• Imaging
• Medical technologies (MedTech)
• Photonics
• Advanced packaging
• Manufacturing
• Advanced substrates
• Power electronics
• Batteries and energy management
• Compound semiconductors
• Solid state lighting
• Displays
• Software
• Memory
10©2018 | www.yole.fr | About Yole Développement
OUR 2018 REPORTS COLLECTION (1/4)
MEMS  SENSORS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the MEMS Industry 2018 – Update
− Silicon Photonics 2018 – Update
− Consumer Biometrics: Hardware  Software 2018 – Update
− Inkjet Functional and Additive Manufacturing for Electronics 2018
− Fingerprint Sensor Applications and Technologies – Consumer Market Focus 2017
− Sensors and Sensing Modules for Smart Homes and Buildings 2017
− Acoustic MEMS and Audio Solutions 2017
− MEMS  Sensors for Automotive Market  Technology Trends 2017
− High End Inertial Sensors 2017
− Magnetic Sensor 2017
o REVERSE COSTING® – STRUCTURE, PROCESS  COST REPORT
– by System Plus Consulting
− Piezo MEMS 2018 *
o PATENT ANALYSES – by KnowMade
− MEMS Microphone – Patent Landscape Analysis
− Knowles MEMS Microphones in Apple iPhone 7 Plus – Patent-to-Product
Mapping 2017
o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade
− MEMS Pressure Sensor 2018 – Market  Technology Report
− MEMS Pressure Sensor Comparison 2018 – Structure, Process  Cost Report
− Gas  Particles 2018 – Market  Technology Report
− Gas  Particles Comparison 2018 – Structure, Process  Cost Report
− LiDARs for Automotive and Industrial Applications 2018 – Market 
Technology Report
− LiDAR for Automotive 2018 – Patent Landscape Analysis
− MEMS Packaging 2017 – Market  Technology Report
− MEMS Packaging Comparison 2017 – Structure, Process  Cost Report
RF DEVICES ANDTECHNOLOGIES
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Wireless technologies (Radar, V2X) for Automotive 2018
− RF Standards and Technologies for Connected Objects 2018
− RF  Photonic Components  Technologies for 5G Infrastructure2018
o REVERSE COSTING® – STRUCTURE, PROCESS  COST REPORT– by System
Plus Consulting
− Automotive Radar Comparison 2018
o PATENT ANALYSES – by KnowMade
− RF Acoustic Wave Filters 2017 – Patent Landscape Analysis
o LINKED REPORTS – by Yole Développement, System Plus Consulting andKnowMade
− 5G impact on RF Front End Modules and Connectivity for Cellphones 2018 – Market
 Technology Report – Update
− RF Front-End Module Comparison 2018 – Structure, Process  Cost Report
− RF Front End Modules for Cellphones 2018 – Patent Landscape Analysis
− Advanced RF System-in-Package for Cellphones 2018 – Market  Technology
Report – Update*
− Advanced RF SiPs for Cell Phones Comparison 2017 – Structure, Process
 Cost Report
− RF GaN Market: Applications, Players, Technology, and Substrates 2018-2023
Market  Technology Report – Update
− RF GaN Comparison 2018* – Structure, Process  Cost Report
− RF GaN 2018 – Patent Landscape Analysis
SOFTWARE
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Consumer Biometrics: Sensors  Software 2018 – Update
− Processing Hardware and Software for AI 2018 - Vol. 1  2
− From Image Processing to Deep Learning, Introduction to Hardware and Software
Update : 2017 version still available / *To be confirmed
11©2018 | www.yole.fr | About Yole Développement
OUR 2018 REPORTS COLLECTION (2/4)
IMAGING  OPTOELECTRONICS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of the Compact Camera Module and Wafer Level Optics
− Industry 2018 – Update
− 3D Imaging and Sensing 2018 – Update
− Sensors for Robotic Vehicles 2018
− Machine Vision for Industry and Automation 2018
− Imagers and Detectors for Security and Smart Buildings 2018
− Uncooled Infrared Imagers 2017
o PATENT ANALYSES – by KnowMade
− iPhone X Dot Projector – Patent-to-Product Mapping
o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade
− Status of the CMOS Image Sensor Industry 2018 – Market  Technology Report -
Update
− CMOS Image Sensor Comparison 2018 – Structure, Process  Cost Report
− CMOS Image Sensors Monitor 2018* – Quaterly Update**
− Camera Module 2017 – Market  Technology Report
− Compact Camera Module Comparison 2018 – Structure, Process  Cost Report
− LiDARs for Automotive and Industrial Applications 2018 – Market  Technology
Report
− LiDAR for Automotive 2018 – Patent Landscape Analysis
ADVANCED PACKAGING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of Advanced Packaging Industry 2018 – Update
− Status of Advanced Substrates 2018: Embedded Die andInterconnects,
Substrate Like PCB Trends
− 3D TSV and Monolithic Business Update 2018 – Update
− Power Modules Packaging 2018 – Update
− Discrete Power Packaging 2018 – Update*
− Status of Panel Level Packaging 2018
− Trends in Automotive Packaging 2018
− Hardware and Software for AI 2018 - Vol. 1  2
− Integrated Passive Devices (IPD) 2018
− Thin-Film Integrated Passive Devices 2018
− Memory Packaging Market and Technology Report 2018 – Update*
o PATENT ANALYSES – by KnowMade
− Hybrid Bonding for 3D Stack – Patent Landscape Analysis
o LINKED REPORTS– by Yole Développement and System Plus Consulting
− Advanced RF System-in-Package for Cellphones 2018 – Market  Technology Report -
Update*
− Advanced RF SiPs for Cell Phones Comparison 2017 – Structure, Process
 Cost Report
− Fan-Out Packaging 2018 – Market  Technology Report – Update*
− Fan-Out Packaging Comparison 2018* – Structure, Process  Cost Report
MANUFACTURING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Wafer Starts for More Than Moore Applications 2018
− Equipment for More than Moore: Technology  Market Trends
for Lithography  Bonding/Debonding 2018
− Polymeric Materials for wafer-level Advanced Packaging 2018
− Laser Technologies for Semiconductor Manufacturing 2017
− Glass Substrate Manufacturing in the Semiconductor Field 2017
− Equipment and Materials for Fan-Out Packaging 2017
− Equipment and Materials for 3D TSV Applications 2017
o LINKED REPORTS – by Yole Développement and System Plus Consulting
− Equipment for More than Moore: Technology  Market Trends for
Lithography  Bonding/Debonding 2018 – Market  Technology Report
− Wafer Bonding Comparison2018 – Structure, Process  Cost Report
Update : 2017 version still available / *To be confirmed
12©2018 | www.yole.fr | About Yole Développement
OUR 2018 REPORTS COLLECTION (3/4)
MEMORY
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Emerging Non Volatile Memory 2018 – Update
− Memory Packaging Market and Technology Report 2018 – Update*
o QUARTERLY UPDATE – by Yole Développement**
− Memory Market Monitor 2018 (NAND  DRAM)
o MONTHLY UPDATE – by Yole Développement**
− Memory Pricing Monitor 2018 (NAND  DRAM)
o REVERSE ENGINEERING  COSTING REVIEW – by System Plus Consulting
− DRAM Technology  Cost Review 2018
− NAND Memory Technology  Cost Review 2018
o PATENT ANALYSES – by KnowMade
− 3D Non-Volatile Memories – Patent Landscape
COMPOUND SEMICONDUCTORS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of Compound Semiconductor Industry 2018*
− GaAs Materials, Devices and Applications 2018
− InP Materials, Devices and Applications 2018
− Bulk GaN Substrate Market 2017
o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade
− Power SiC 2018: Materials, Devices, and Applications – Market  Technology
Report – Update
− SiC Transistor Comparison 2018 – Structure, Process  Cost Report
− Power SiC 2018 – Patent Landscape Analysis
− Power GaN 2018: Materials, Devices, and Applications – Market  Technology Report
– Update
− GaN-on-Silicon Transistor Comparison 2018 – Structure, Process  Cost Report
− Status of the GaN IP – Patent Watch 2018  Patent Activity 2017
− RF GaN Market: Applications, Players, Technology, and Substrates 2018-2023
– Market  Technology Report – Update
− RF GaN – Patent Landscape Analysis
POWER ELECTRONICS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Status of Power Electronics Industry 2018 – Update
− Discrete Power Packaging 2018 – Update*
− Power Electronics for Electric Vehicles 2018 – Update
− Integrated Passive Devices (IPD) 2018
− Wireless Charging Market Expectations and Technology Trends 2018
− Thermal Management Technology and Market Perspectives in Power
− Electronics and LEDs 2017
− Gate Driver 2017
− Power MOSFET 2017
− IGBT 2017
− Market Opportunities for Thermal Management Components in
Smartphones 2017
o LINKED REPORTS – by Yole Développement, System Plus Consulting
and KnowMade
− Power Modules Packaging 2018 – Market  Technology Report – Update
− Automotive Power Module Packaging Comparison2018 – Structure,
Process  Cost Report
− Power ICs Market Monitor 2018 – Quaterly Update**
− Power ICs Market Comparison 2018* – Structure, Process  Cost Report
BATTERY AND ENERGY MANAGEMENT
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Li-ion Battery Packs for Automotive and Stationary Storage Applications 2018 –
Update
o PATENT ANALYSES – by KnowMade
− Status of the Battery Patents – Patent Watch 2018  Patent Activity 2017
o LINKED REPORTS – by Yole Développement and KnowMade
− Solid State Electrolyte Battery 2018 – Market  Technology Report
− Solid-State Batteries 2018 – Patent Landscape Analysis
Update : 2017 version still available / *To be confirmed / ** Can not be selected within an Annual Subscription offer
13©2018 | www.yole.fr | About Yole Développement
OUR 2018 REPORTS COLLECTION (4/4)
SOLID STATE LIGHTING
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− IR LEDs and Lasers 2018: Technology, Industry and Market Trends – Update
− Automotive Lighting 2018: Technology, Industry and Market Trends – Update
− UV LEDs 2018: Technology, Industry and Market Trends – Update
− LiFi: Technology, Industry and Market Trends
− LED Lighting Module Technology, Industry and Market Trends 2017
− CSP LED Lighting Modules
− Phosphors  Quantum Dots 2017 - LED Downconverters for Lighting  Displays
− Horticultural Lighting 2017
o LINKED REPORTS – by Yole Développement and System Plus Consulting
− VCSELs 2018: Technology, Industry and Market Trends – Market  Technology
Report
− VCSELs Comparison 2018 – Structure, Process  Cost Report
DISPLAYS
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− Quantum Dots and Wide Color Gamut Display Technologies 2018 – Update
− Displays and Optical Vision Systems for VR/AR/MR 2018
− MicroLED Displays 2018 – Market  Technology Report – Update
o PATENT ANALYSES – by KnowMade
− MicroLED Display – Patent Landscape Analysis
MEDTECH
o MARKET AND TECHNOLOGY REPORT – by Yole Développement
− BioMEMS  Non Invasive Emerging Biosensors: Microsystems for Medical
− Applications 2018 – Update
− Point-of-Need Testing Application of Microfluidic Technologies 2018 – Update
− Neurotechnologies and Brain Computer Interface 2018
− CRISPR-Cas9 Technology: From Lab to Industries 2018
− Ultrasound technologies for Medical, Industrial and Consumer 2018
− Inkjet Functional and Additive Manufacturing for Electronics 2018
− Liquid Biopsy: from Isolation to Downstream Applications 2018
− Chinese Microfluidics Industry 2018
− Scientific Cameras for the Life Sciences  Analytical Instrumentation
Laboratory Markets 2018*
− Artificial Organ Technology and Market 2017
− Connected Medical Devices Market and Business Models 2017
− Status of the Microfluidics Industry 2017
− Organs-On-Chips 2017
− Solid-State Medical Imaging 2017
− Medical Robotics Market  Technology Analysis 2017
o PATENT ANALYSES – by KnowMade
− Microfluidic IC Cooling – Patent Landscape
− Circulating Tumor Cell Isolation – Patent Landscape
− OCT Medical Imaging – Patent Landscape
− Pumps for Microfluidic Devices – Patent Landscape 2017
− Microfluidic Technologies for Diagnostic Applications– Patent Landscape 2017
− FLUIDIGM – Patent Portfolio Analysis 2017
− Consumer Physics SCiO Molecular Sensor – Patent-to-Product Mapping 2017
o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade
− Organs-On-Chips 2017 – Market  Technology Report
− Organ-on-a-Chip– Patent Landscape Analysis
Update : 2017 version still available / *To be confirmed
14©2018 | www.yole.fr | About Yole Développement
OUR 2017 PUBLISHED REPORTS LIST (3/3)
OUR PARTNERS’ REPORTS
PATENT ANALYSES – by KnowMade
− Wireless Charging Patent LandscapeAnalysis
− RF Acoustic Wave Filters Patent LandscapeAnalysis
− NMC Lithium-Ion Batteries Patent LandscapeAnalysis
− Pumps for Microfluidic Devices Patent Landscape
− III-N PatentWatch
− FLUIDIGM Patent Portfolio Analysis
− Knowles MEMS Microphones in Apple iPhone 7 Plus Patent-to-Product Mapping 2017
− Consumer Physics SCiO Molecular Sensor Patent-to-Product Mapping
− Patent Licensing Companies in the Semiconductor Market - Patent Litigation Risk and Potential Targets
− Microfluidic Technologies for Diagnostic Applications Patent Landscape
TEARDOWN  REVERSE COSTING – by System Plus Consulting
More than 60 teardowns and reverse costing analysis and cost simulation tools published in 2017
MORE INFORMATION
o All the published reports from theYole Group of Companies are available on our website www.i-Micronews.com.
o Ask for our Bundle Subscription offers: With our bundle offer, you choose the number of reports you are interested in and select the related offer. You then haveup
to 12 months to select the required reports from the Yole Développement, System Plus Consulting and KnowMade offering. Pay once and receive the reports
automatically (multi-user format). Contact your sales team according to your location (see the last slide).
15©2018 | www.yole.fr | About Yole Développement
MICRONEWS MEDIA
o About Micronews Media
To meet the growing demand for market,
technological and business information,
Micronews Media integrates several tools able
to reach each individual contact within its
network.We will ensure you benefit from this.
ON L IN E ON SITE IN PERSON
@Micronews e-newsletter
i-Micronews.com
i-Micronewsjp.com
FreeFullPDF.com
Events Webcasts
Unique, cost-effective ways
to reach global audiences.
Online display advertising
campaigns are great strategies
for improving your
product/brand visibility.They
are also an efficient way to
adapt with the demands of the
times and to evolve an effective
marketing plan and strategy.
Brand visibility,networking
opportunities
Today's technology makes it
easy for us to communicate
regularly, quickly,and
inexpensively – but when
understanding each other is
critical, there is no substitute
for meeting in-person.Events
are the best way to exchange
ideas with your customers,
partners, prospects while
increasing your brand/product
visibility.
Targeted audience
involvement equals clear,
concise perception of your
company’s message.
Webcasts are a smart,
innovative way of
communicating to a wider
targeted audience.Webcasts
create very useful,dynamic
reference material for
attendees and also for
absentees, thanks to the
recording technology.
Benefit from the i-Micronews.com
traffic generated by the 11,200+
monthly unique visitors, the
10,500+ weekly readers of
@Micronew se-newsletter
Several key events planned for
2018 on different topics to
attract 120 attendees on average
Gain new leads for your business
from an average of 340
registrants per webcast
Contact: Camille Veyrier (veyrier@yole.fr),Marketing  Communication Project Manager
16©2018 | www.yole.fr | About Yole Développement
CONTACT INFORMATION
o CONSULTINGANDSPECIFICANALYSIS,REPORT
BUSINESS
• North America:
• Steve LaFerriere, Senior Sales Director for Western US 
Canada
Email: laferriere@yole.fr – + 1 310 600-8267
• Troy Blanchette, Senior Sales Director for Eastern US 
Canada
Email: troy.blanchette@yole.fr – +1 704 859-0453
• Japan  Rest ofAsia:
• Takashi Onozawa, General Manager,Asia Business
Development (Korea, Singapore, India  ROA)
Email: onozawa@yole.fr - +81 34405-9204
• Miho Othake, Account Manager (Japan)
Email: ohtake@yole.fr - +81 3 4405 9204
• Itsuyo Oshiba, Account Manager (Japan)
Email: oshiba@yole.fr - +81-80-3577-3042
• Greater China: MavisWang, Director of Greater China Business
Development
Email: wang@yole.fr - +886 979 336 809
• Europe: Lizzie Levenez,EMEA Business Development Manager
Email: levenez@yole.fr - +49 15 123 544 182
• RoW: Jean-Christophe Eloy,CEO  President,Yole Développement
Email eloy@yole.fr - +33 4 72 83 01 80
o FINANCIAL SERVICES (in partnershipwithWoodside
CapitalPartners)
• Jean-Christophe Eloy,CEO  President
Email: eloy@yole.fr - +33 4 72 83 01 80
• Ivan Donaldson,VP of Financial Market Development
Email: ivan.donaldson@yole.fr - +1 208 850 3914
o GENERAL
• Public Relations: leroy@yole.fr - +33 4 72 83 01 89
• Email: info@yole.fr - +33 4 72 83 01 80
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Chinese Microfluidics Industry 2018 Report by Yole Developpement

  • 1. From Technologies to Market Chinese Microfluidics Industry 2018 Report Sample © 2018
  • 2. 2 3M, Abaxis, Abbott, Affymetrix, Agilent Technologies, Alere,Anatech, BaiCare, BD, Beijing Bohui Innovation Technologies, Beijing e- science, Beijing Genomics Institute (BGI Shenzhen), Beijing Unibio, Beijing University of Technology, Berry Genomics, Biocartis, bioMérieux, Caliper Life Sciences (PerkinElmer), CapitalBio, Celsee, Cepheid, Chinese Academy of Sciences, Chongqing University, Clearbridge Biomedics, CNRS, Corning, Coyote Biosciences, Dalian Institute of Chemical Physics, Dalian University of Technology, Daohui Biotech, Denz Bio-Medical, Digital Biosystems, Dolomite, Each-reach (Rongzhi Biotech), Elveflow, Excbio, Fapon, Fluidigm, Fluigent, Foxgene, Fudan University, Funai Electric, Genetel Pharmaceuticals, Getein Biotech, Guangzhou Sio Optics, Harbin Institute of Technology, Harvard College, HealthDigit, Heto, Hicomp Microtech, Highland Best, Hochuen, Honeywell, HP, Huakairui, IBM, Illumina, Institute of High Energy Physics, Inzign, Jiangsu University, JIER Machine Tool Group, LabSmith, Lianer Technology, Little Things Factory, Maccura, Mesosbiosys, Micronit, Micropoint Biosciences, Micrux Technologies, Mindray, MiTASChip, MNChip, Nanoctr, NanoEntek, NanoLite Systems, Nanomed Skincare, Oxford Nanopore Technologies, Pacific Biosciences, Peking University, Philips, Prinzen Bio (Shanghai Yanzan Biotechnology), Purui Kang, PushKang Biotechnology, Qiagen, Quanterix, Quidel, Ray Biotech, Rayme Biotech, Renji Hospital, Robert Bosch, Roche, Samsung Electronics, Schott, Sensilicon (Shanghai Central Core Electronics), Shanghai Baio Technology, Shanghai Biochip, Shanghai Biotechnology Corporation, Shanghai Hengxin Biotechnology, Shanghai Industrial µTechnology Research Institute (SITRI), Shanghai Jiao Tong University, Shenyang Machine Tool, SIASUN Robot & Automation, Silex Microsystems, Sinochips, Solvay, Sony, Southeast University, Superchip Technology, Suzhou Genso Optoelectronic Technology, Suzhou Hailu Biotech (Halo),Tecnisco,Thermo Fisher Scientific, Tianjin Biochip,Tinker Bio,Tongfang Biochip,Tsinghua University, University of California,Watmind,Wenchang Chip,Wenhao Chip, Yaneng Bio,Yulong Biomedical, Zhejiang University… … and more! LIST OF COMPANIES MENTIONED IN THIS REPORT 170+ slides of market and technology analysis Information gathered through direct discussions with players all along the supply chain ©2018 | www.yole.fr | Chinese Microfluidics Industry | Sample
  • 3. 3 Biography & contact ABOUTTHE AUTHORS Sébastien Clerc Sébastien Clerc works as a Medical Technologies & Market Analyst at Yole Développement (Yole). As part of the Medical Technologies (MedTech) business unit, Sébastien has authored a collection of market and technology reports dedicated to topics such as microfluidics, point-of-care, MEMS for healthcare applications, and connected medical devices. In parallel, he is regularly involved in custom projects including strategic marketing, technology scouting, and technology evaluation, designed to help academic and industrial players in their innovation processes. Leveraging his technology and market expertise, Sébastien has spoken at more than 10 industry conferences worldwide in the last two years. Sébastien graduated from Grenoble Institute of Technology (Grenoble INP - Grenoble, France) with a master’s degree in Biomedical Technologies. He then completed his cursus with a master’s degree in Innovation and Technology Management from the same institute. Email: clerc@yole.fr Hong LIN Dr. Hong Lin works at Yole Développement (Yole), as a Technology and Market Analyst, Compound Semiconductors within the Power & Wireless division since 2013. She is specialized in compound semiconductors and provides technical and economic analysis. Before joining Yole Développement, she worked as R&D engineer at Newstep Technologies. She was in charge of the development of cold cathodes by PECVD for visible and UV lamp applications based on nanotechnologies. She holds a Ph.D in Physics and Chemistry of materials. Email: lin@yole.fr
  • 4. 4 OBJECTIVES OF THE REPORT • Identify microfluidics applications in China and understand the associated ecosystem • Identify the local technologies and understand their ability to answer market needs • Provide a mapping of the players at each level of the supply chain • Explain how the Chinese players compare to western players in terms of expertise, know-how and capabilities, how they are working together, and understand if there is a threat for western players • Understand how this ecosystem may evolve • Provide market data 2016 and 2017 and provide forecasts 2017 – 2023 • Provide a brief overview of the microfluidic Intellectual Property landscape in China • Provide company profiles of all the identified Chinese players • Obtain a global vision of the Chinese microfluidic market, taking into account real industrial concerns, along the whole supply chain, and considering both Chinese and foreign players
  • 5. 5 TABLE OF CONTENTS (1/2) Executive Summary p.10 Landscape overview p.40 Definitions and introduction Mapping of Chinese microfluidic players Market landscape Funding model Comparison between China and other countries China’s strengths Why is the government supporting microfluidics? Poor ecosystem for system development Drivers for microfluidics adoption in China Chinese companies starting business abroad Conclusions Patent analysis p.67 Market data and forecasts p.84 Microfluidic-based products (volume) Microfluidic-based products (value) Microfluidic-based products: market share Microfluidic devices (value) Microfluidic-based products: value of the chip Microfluidic devices: market share of Chinese fabs What tomorrow could look like Several applications, different dynamics p.94 Applications & dynamics Pharma chips production NGS in China: market share, BGI strategy Some applications/technologies are expected to grow rapidly Foreign microfluidic companies in China Conclusions
  • 6. 6 TABLE OF CONTENTS (2/2) Supply chain and value chain p.108 Introduction Microfluidic cartridge production: different models Repartition of Chinese players per type of company Microfluidic chip processing equipment Materials Players capabilities Examples of production collaborations Foreign players in China Distributors for western players Other examples of collaboration How do fabs position? Technical capabilities Chinese players working for western companies Demand for glass microfluidics Reagent deposition capabilities Interactions between world regions Criteria for selecting a development and industrialization partner Value chain for point-of-need applications Conclusions Examples of products & company profiles p.133 Regulatory & market access p.168 Report conclusion p.177
  • 7. 7 SCOPE OF THE REPORT This report aims to explain the status of the microfluidics industry in Mainland China (Taiwan and Hong-Kong are thus not included). It covers: - Chinese microfluidic players having activities in China and abroad - Foreign microfluidic players having activities in China Hong Kong Taiwan
  • 8. 8 INTRODUCTION Definition: our vision of microfluidics What do we consider as microfluidics? • Microfluidics is the science and technology that deals with the manipulation of fluids usually in the range of microliters (10-6) to picoliters (10-12) and/or in networks of micrometer-size channels. • Our definition of microfluidics encompass: Active fluid management techniques for very small volumes Micro-fabricated devices with channels below ~500µm in size And/or
  • 9. 9 INTRODUCTION Our vision of the microfluidics market • We divided these technologies in 2 components in order to better explain the microfluidics market: • Microfluidic device: • The microfluidic device is defined as the microfluidic technology manufactured. It can be a chip, a cartridge, a dispensing tool, a flow control component and other types of microfluidic components. • The microfluidic chips represent 85% of the market of the microfluidic device. • Microfluidic product: • The microfluidic product is defined as the microfluidic device packaged for sale for the end-user. • The reagents are added to the device to create the product if needed. • For example in point-of-care applications the microfluidic product is a microfluidic device where reagents are added, one test corresponds to one microfluidic cartridge (even if it is sometimes possible to make several analysis on the product (multiplexing). • Example of the AlereTriage method Alere Triage® MeterPro Source: Alere Microfluidic device: chip Microfluidic product: cartridge packaged with reagents Alere Triage® Cardiac Panel Source:Alere Microfluidic analyzer Not taken into account in the market analysis Most microfluidic devices are chips. When combined with biological content, these chips become products
  • 10. 10 MICROFLUIDIC APPLICATIONS DEFINITION Microfluidic technology is used everywhere Microfluidic Applications Clinical & Veterinary Diagnostics Point of Care Diagnostics Pharma & Life Sciences Research Analytical Devices Industrial, Environmental & Agro-Food Drug Delivery Micro Reaction - Flow Chemistry • Clinical and Veterinary Diagnostics Laboratory equipment for clinical and veterinary diagnostics • Point-of-Care Diagnostics Out-of-the-lab diagnostic equipment for near-patient testing, intensive care, doctor’s offices, home testing • Pharmaceutical and Life Science Research Microfluidic devices for drug discovery and screening, genomics, proteomics, cell analysis… • Analytical Devices Microfluidic chips and columns for mass spectrometry, chromatography and HPLC sample preparation • Industrial, Environmental and Agro-FoodTesting Microfluidic-based tests for quality/process control and water testing (pesticides, bacteria, etc.). Includes military, security and forensics applications • Drug delivery Microfluidic devices for drug delivery, such as inhalers, microneedles and implantable micropumps • Micro Reaction – Flow Chemistry Microfluidic devices for micro reaction involved in research or in pilot-production units
  • 11. 11 CHINESE MICROFLUIDIC LANDSCAPE: INTRODUCTION • In recent years, China has become very active in point of care, high-throughput sequencing and other medical diagnostics. In 2014, 229 Chinese companies active in microfluidics were identified*. We believe this number has exploded in the past few years thanks to the government’s policy wanting to ensure a strong position of China in this field, the availability of local inexpensive manufacturing technologies and the creation of many spin off companies from research institutes. • Indeed, the Chinese government has set up a strategic plan to comprehensively upgrade the Chinese industry and make the country a major player, independent from other countries. This plan, named Made in China 2025, includes a focus on pharmaceuticals and medical devices. Companies involved in these sectors will benefit from almost unlimited funding by 2025 to catch up with foreign industries and take back significant market share in China. As a key tool for diagnostics and life sciences applications, microfluidic technology will for sure benefit of money spend in the context of this strategic plan. • *Source: MinacNed
  • 12. 12 CONTENT OF THE REPORT Chinese microfluidic landscape description
  • 13. 13 CONTENT OF THE REPORT Patent analysis
  • 14. 14 CONTENT OF THE REPORT Market data and forecasts
  • 15. 15 CONTENT OF THE REPORT Description of microfluidic applications in China
  • 16. 16 CONTENT OF THE REPORT Supply and value chain analysis (1/2)
  • 17. 17 CONTENT OF THE REPORT Supply and value chain analysis (2/2)
  • 18. 18 CONTENT OF THE REPORT Company profiles and examples of products
  • 20. The Chinese government has created a strategic plan to comprehensively upgrade the country’s industrial sector and make China a major player that is independent from other countries. This plan, “Made in China 2025”, includes a focus on pharmaceuticals and medical devices. Companies involved in these sectors will benefit from almost unlimited funding by 2025, with the goal to compete with foreign industries and retake significant market share. As a key tool for diagnostics and life sciences applications, microfluidic technology will surely benefit from this massive spend. Indeed, the chinese diagnostics market is currently dominated by large international companies like Roche and Abbott, but new Chinese companies are rising up to compete with them. The opportunity is huge for these emerging Chinese players, because the current domination of foreign players results in products that are considered too expensive and often way beyond reimbursement thresholds. Thus, Chinese players able to propose similar solutions at a lower price will seriously threaten these giants’ position in the Chinese market. We are not there yet because performance and quality still don’t meet the expectations, but the path to 2025 is long and China’s industry is improving rapidly. Moreover, demand is growing quickly: indeed, China already hastheworld’slargestpopulation,onewhichisaging rapidly and thus needs improved care. Additionally, the end of the “one-child policy” has resulted in numerous births and an increased demand in areas such as non-invasive prenatal testing. For all these reasons, the Chinese microfluidic market will be strongly impacted. Yole Développement (Yole)’s analysts expect that the market for microfluidic-based products sold by Chinese players will grow at a CAGR2017-2023 of 28%, from $171M in 2017 to $754.1M in 2023. CHINESE MICROFLUIDICS INDUSTRY 2018 Market & Technology report - July 2018 WITH AN EYE TOWARDS 2025, CHINA HAS LAUNCHED A DEEP TRANSFORMATION OF ITS INDUSTRIAL SECTOR Will the Chinese microfluidics industry change the worldwide microfluidic landscape? KEY FEATURES • Mapping of Chinese microfluidic players • Analysis of both local and foreign players’ sales and positioning in China • Market landscape overview • Comparison between China and other countries • Drivers for microfluidics adoption in China • Market data and forecasts 2017 - 2023 for microfluidic-based products and for microfluidic devices, in volume (units) and in value ($M) • Analysis of the dynamic applications, with a focus on next- generation sequencing • Supply and value chain analysis, with overview of Chinese players’ capabilities and limitations • Company profiles • First-level patent analysis • First-level regulatory and market access information (Yole Développement, July 2018) Tianjin Beijing Hangzhou Wuhan (Each-reach) Chengdu Suzhou Shanghai Shenzhen *Non-exhaustive list of companies THE CHINESE MICROFLUIDICS INDUSTRY: A FAST-MOVING ECOSYSTEM As a consequence of governmental support, numerous Chinese companies were recently spun- off from several universities. Starting from 2002, Government funding for microfluidic research and microfluidic companies has reached several tens of millions yuan per year, with a significant explosion in recent years. The government is also recalling Chinese executives and engineers who have worked overseas for years in order to lead these new Chinese companies and increase their chances of success. Market demand is growing, and students in microfluidics are being recruited before they even graduate. Yole has identified 40+ Chinese companies involved in microfluidic device manufacturing 2018 - Mapping of Chinese microfluidic players*
  • 21. CHINESE MICROFLUIDICS INDUSTRY 2018 CHINESE MICROFLUIDIC COMPANIES: A THREAT TO FOREIGN PLAYERS? Among the Chinese companies that look promising, Bohui and Micropoint are two which have full capabilities for manufacturing their microfluidic-based products, and their position is clearly to propose alternatives to the diagnostic products sold by international giants. Such companies are growing well and finding success by proposing similar solutions to the international giants, but at a much lower price. Thanks to this strategy, some Chinese companies are beginning to attract foreign customers who cannot afford similar services at Western prices. Currently, quality is still inferior to what foreign companies can offer, but this could significantly change over the next 5 - 10 years. Globally, this is the strategy of most Chinese microfluidic players, at all levels of the supply chain: propose “good enough” products or services at a low cost, gain contracts, and grow quickly. The most obvious example is that of BGI. The genomics company has released DNA sequencers over the past three years, first in China and now worldwide. Though BGI’s technology is said to still trail the field’s gold standard (i.e. Illumina), its aggressive pricing policy allows it to rapidly gain market share and make significant progress in terms of performance. Interestingly, numerous people share the same opinion: “BGI will kill Illumina”. It may be too early to make such a bold statement, but one thing is sure: certain Chinese companies have the potential to be a real threat to Western players, which must find solutions to contest these Asian newcomers in their respective markets, at all levels of the supply chain. This report details the current capabilities of more than 25 Chinese microfluidic players and furnishes 30+ company profiles detailing who these players are. and/or integration. Though a few companies (i.e. CapitalBio) have existed since the 2000s, most of these microfluidic companies have been around only a few years, and some of them already have products on the market. In fact, the timeline from company inception to product commercialization seems much shorter in China than abroad. Today, the Chinese supply chain’s maturity is similar to what Europe and the USA’s supply chain resembled ten years ago: very few companies have full capabilities (from design and prototyping to mass manufacturing and back-end processing), and only a few projects reach mass production. However, China’s evolution should be much faster, and it won’t take the Chinese industry 10 years to catch up. The questions are: “What will be the first significant commercial success?” and “Who will be the Chinese versions of Cepheid and Abaxis, two American diagnostic companies that in the 2000s found success with microfluidic technology and were recently acquired by diagnostic giants?” In this report, Yole’s analysts explain how China’s ecosystem may evolve over the next few years, whether foreign players can survive, and how some Chinese players are destined for big things. How the Chinese microfluidic landscape could appear in a few years* (Yole Développement, July 2018) Microfluidics- based revenue Chinese companies Foreign companies Several international giants with decreasing market share Numerous small Chinese players with medium revenue / low market share Few foreign players (decreasing number) with low revenue / market share Several Chinese giants *Non-exhaustive list of companies Next-generation sequencing market share in China: what could happen by 2025? (Yole Développement, July 2018) 67% 57% Year 2017 US$ 379 MILLION 9% 12% US$ 1,854 MILLION 13% 8% 24% 8% Others 1% Others 2 % CAGR2017-2025 : 22% And more… Year 2025
  • 22. MARKET TECHNOLOGY REPORT COMPANIES CITED IN THE REPORT (non exhaustive list) 3M, Abaxis, Abbott, Affymetrix, Agilent Technologies, Alere, Anatech, BaiCare, BD, Beijing Bohui InnovationTechnologies,Beijinge-science,BeijingGenomicsInstitute(BGIShenzhen),BeijingUnibio,Beijing University of Technology, Berry Genomics, Biocartis, bioMérieux, Caliper Life Sciences (PerkinElmer), CapitalBio, Celsee, Cepheid, Chinese Academy of Sciences, Chongqing University, Clearbridge Biomedics, CNRS, Corning, Coyote Biosciences, Dalian Institute of Chemical Physics, Dalian University of Technology, Daohui Biotech, Denz Bio-Medical, Digital Biosystems, Dolomite, Each-reach (Rongzhi Biotech), Elveflow, Excbio, Fapon, Fluidigm, Fluigent, Foxgene, Fudan University, Funai Electric, Genetel Pharmaceuticals, Getein Biotech, Guangzhou Sio Optics, Harbin Institute of Technology, Harvard College, HealthDigit, Heto, Hicomp Microtech, Highland Best, Hochuen, Honeywell, HP, Huakairui, IBM, Illumina, Institute of High Energy Physics, Inzign, Jiangsu University, JIER Machine Tool Group, LabSmith, Lianer Technology, Little Things Factory, Maccura, Mesosbiosys, Micronit, Micropoint Biosciences, Micrux Technologies, Mindray, MiTASChip, MNChip, Nanoctr, NanoEntek, NanoLite Systems, Nanomed Skincare, Oxford Nanopore Technologies, Pacific Biosciences, Peking University, Philips, Prinzen Bio (Shanghai Yanzan Biotechnology), Purui Kang, PushKang Biotechnology, Qiagen, Quanterix, Quidel, Ray Biotech, Rayme Biotech, Renji Hospital, Robert Bosch, Roche, Samsung Electronics, Schott, Sensilicon (Shanghai Central Core Electronics), Shanghai Baio Technology, Shanghai Biochip, Shanghai Biotechnology Corporation, Shanghai Hengxin Biotechnology, Shanghai Industrial µTechnology Research Institute (SITRI), Shanghai Jiao Tong University, Shenyang Machine Tool, SIASUN Robot Automation, Silex Microsystems, Sinochips, Solvay, Sony, Southeast University, Superchip Technology, Suzhou Genso Optoelectronic Technology, Suzhou Hailu Biotech (Halo), Tecnisco, Thermo Fisher Scientific, Tianjin Biochip, Tinker Bio, Tongfang Biochip, Tsinghua University, University of California, Watmind, Wenchang Chip, Wenhao Chip, Yaneng Bio, Yulong Biomedical, Zhejiang University, and more... Executive Summary 10 Landscape overview 40 Definitions and introduction Mapping of Chinese microfluidic players Market landscape Funding model Comparison between China and other countries China’s strengths Why is the Chinese government supporting microfluidics? Poor ecosystem for system development Drivers for microfluidics adoption in China Chinese companies starting businesses abroad Conclusions Patent analysis 67 Market data and forecasts 84 Microfluidic-based products (volume) Microfluidic-based products (value) Microfluidic-based products - market share Microfluidic devices (value) Microfluidic-based products - chip value Microfluidic devices - Chinese foundries’ market share What tomorrow could look like Several applications, different dynamics 94 Applications dynamics Pharma chip production NGS in China - market share, BGI strategy Some applications/technologies are expected to grow rapidly Foreign microfluidic companies in China Conclusions Supply chain and value chain 108 Introduction Microfluidic cartridge production - different models Repartition of Chinese players, per company type Microfluidic chip processing equipment Materials Players’ capabilities Examples of production collaborations Foreign players in China Distributors for Western players Other collaboration examples How do foundries position? Technical capabilities Chinese players working for Western companies Glass microfluidics - demand Reagent deposition capabilities Interactions between world regions Criteria for selecting a development and industrialization partner Value chain for point-of-need applications Conclusions Examples of products and company profiles 133 Regulatory and market access 168 Report conclusion 177 TABLE OF CONTENTS (complete content on i-Micronews.com) OBJECTIVES OF THE REPORT • Publish a global vision of the Chinese microfluidic market, taking into account real industrial concerns along the whole supply chain, and considering Chinese and foreign players • Identify microfluidics applications in China and understand the associated ecosystem • Identify the local technologies and understand their ability to answer market needs • Map players at each level of the supply chain • Explain how Chinese players compare to Western players in terms of expertise, know-how, capabilities, and how they work together, and understand whether they can threaten Western players • Examine how this ecosystem might evolve • Provide 2016 - 2017 market data and furnish forecasts for 2017 - 2023 • Deliver a brief overview of China’s microfluidic IP landscape • Provide company profiles for all identified Chinese players AUTHORS Sébastien Clerc worksasaTechnologies Market Analyst, Microfluidics Medical Technologies at Yole Développement (Yole). Sébastien authored a collection of market and technology reports dedicated to topics such as microfluidics, point-of-care and more. In parallel, he is daily involved in custom projects. Thanks to its technology market expertise, Sébastien has spoken in more than 10 industry conferences worldwide over the last 2 years. Sébastien Clerc is graduated from Grenoble Institute of Technology (Grenoble INP - Grenoble, France) with a Master degree in Biomedical Technologies. Then he completed his cursus with a Master degree in Innovation and TechnologyManagementinthesameinstitute. Find more details about this report here: RELATED REPORTS Benefit from our Bundle Annual Subscription offers and access our analyses at the best available price and with great advantages • Point-of-Need Testing: Application of Microfluidic Technologies • Microfluidic Technologies for Diagnostic Applications Patent Landscape Find all our reports on www.i-micronews.com Dr.HongLinworksatYoleDéveloppement (Yole), as a Technology and Market Analyst, Compound Semiconductors within the Power Wireless division since 2013. She is specialized in compound semiconductors and provides technical and economic analysis.BeforejoiningYoleDéveloppement, she worked as RD engineer at Newstep Technologies. She was in charge of the development of cold cathodes by PECVD for visible and UV lamp applications based on nanotechnologies. She holds a Ph.D in Physics and Chemistry of materials.
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  • 24. © 2018 Yole Développement From Technologies to Market Source: Wikimedia Commons
  • 25. 2©2018 | www.yole.fr | About Yole Développement YOLE DEVELOPPEMENT – 4 DIVISIONS Life Sciences Healthcare o Microfluidic o BioMEMS o Inkjet Printing o Solid-State Medical Imaging BioPhotonics o BioTechnologies Power Wireless o RF DevicesTechnology o Compound Semiconductors Emerging Materials o Power Electronics o Batteries Energy Management Semiconductor Software o Package Assembly Substrates o SemiconductorManufacturing o Memory o Software Computing Photonics, Sensing Display o Solid-State Lighting Display o MEMS,Sensors Actuators o Imaging o Photonics Optoelectronics Semiconductor Software Power Wireless Photonics, Sensing Display Life Sciences Healthcare
  • 26. 3©2018 | www.yole.fr | About Yole Développement 3 BUSINESS MODELS o Consulting and Analysis • Market data research, marketing analysis • Technology analysis • Strategy consulting • Reverse engineering costing • Patent analysis • Design and characterization of innovative optical systems • Financial services (due diligence, MA with our partner) www.yole.fr o Syndicated reports • Market technology reports • Patent investigation and patent infringement risk analysis • Teardowns reverse costing analysis • Cost simulation tool www.i-Micronews.com/reports o Media • i-Micronews.com website • @Micronews e-newsletter • Communication webcast services • Events:TechDays,forums,… www.i-Micronews.com
  • 27. 4©2018 | www.yole.fr | About Yole Développement 6 COMPANIES TO SERVEYOUR BUSINESS Due diligence www.yole.fr Manufacturing costs analysis Teardown and reverse engineering Cost simulation tools www.systemplus.fr Market,technology and strategy consulting www.yole.fr IP analysis Patent assessment www.knowmade.fr Innovation and business maker www.bmorpho.com Design and characterization of innovative optical systems www.piseo.fr Yole Group of Companies
  • 28. 5©2018 | www.yole.fr | About Yole Développement OUR GLOBAL ACTIVITY 30%of our business 40%of our business 30%of our business Greater China office Yole Japan HQ in Lyon Nantes Paris Nice Vénissieux Europe office Frankfurt Hsinchu Tokyo Yole Inc. Phoenix Yole Korea Seoul Palo Alto
  • 29. 6©2018 | www.yole.fr | About Yole Développement ANALYSIS SERVICES - CONTENT COMPARISON Technology and Market Report Leadership Meeting QA Service Depth of the analysis Breadthoftheanalysis Meet the Analyst Custom Analysis High High Low
  • 30. 7©2018 | www.yole.fr | About Yole Développement SERVINGTHE ENTIRE SUPPLY CHAIN Our analysts provide market analysis, technology evaluation, and business plans along the entire supply chain Integrators,end- users and software developpers Device manufacturers Suppliers:material,equipment, OSAT,foundries… Financial investors,RD centers
  • 31. 8©2018 | www.yole.fr | About Yole Développement SERVING MULTIPLE INDUSTRIAL FIELDS We work across multiples industries to understand the impact of More-than- Moore technologies from device to system FromA to Z… Transportation makers Mobile phone and consumer electronics Automotive Medical systems Industrial and defense Energy management
  • 32. 9©2018 | www.yole.fr | About Yole Développement o Yole Développement, System Plus Consulting, KnowMade and PISEO, all part of Yole Group of Companies, keep on increasing their collaboration to offer, in 2018, a collection of 150+ reports. Combining respective expertise and methodologies from the 4 companies, the reports aim to provide market technology analysis, patent investigation and patent infringement risk analysis, teardowns reverse costing analysis.They cover: o You are looking for: • An analysis of your product market • A review of your competitors evolution • An understanding of your manufacturing and production costs • An understanding of your industry technology roadmap and related IPs • A clear view on the evolution of the supply chain… Our reports are for you! The combined team of 60+ experts (PhDs, MBAs, industry veterans…) from Yole Développement, System Plus Consulting, KnowMade and PISEO, collect information, identify the trends, the challenges, the emerging markets, the competitive environments and turn it into results to give you a complete picture of your industry landscape. In the past 20 years, we worked on more than 1 700 projects, interacting with technology professionals and high level opinion makers from the main players of the industry. o In 2018, Yole Group of Companies plan to publish +150 reports.Gain full benefit from our Bundled Offer and receive at least a 36% discount. REPORTS COLLECTION www.i-Micronews.com • MEMS Sensors • RF devices technologies • Imaging • Medical technologies (MedTech) • Photonics • Advanced packaging • Manufacturing • Advanced substrates • Power electronics • Batteries and energy management • Compound semiconductors • Solid state lighting • Displays • Software • Memory
  • 33. 10©2018 | www.yole.fr | About Yole Développement OUR 2018 REPORTS COLLECTION (1/4) MEMS SENSORS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the MEMS Industry 2018 – Update − Silicon Photonics 2018 – Update − Consumer Biometrics: Hardware Software 2018 – Update − Inkjet Functional and Additive Manufacturing for Electronics 2018 − Fingerprint Sensor Applications and Technologies – Consumer Market Focus 2017 − Sensors and Sensing Modules for Smart Homes and Buildings 2017 − Acoustic MEMS and Audio Solutions 2017 − MEMS Sensors for Automotive Market Technology Trends 2017 − High End Inertial Sensors 2017 − Magnetic Sensor 2017 o REVERSE COSTING® – STRUCTURE, PROCESS COST REPORT – by System Plus Consulting − Piezo MEMS 2018 * o PATENT ANALYSES – by KnowMade − MEMS Microphone – Patent Landscape Analysis − Knowles MEMS Microphones in Apple iPhone 7 Plus – Patent-to-Product Mapping 2017 o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade − MEMS Pressure Sensor 2018 – Market Technology Report − MEMS Pressure Sensor Comparison 2018 – Structure, Process Cost Report − Gas Particles 2018 – Market Technology Report − Gas Particles Comparison 2018 – Structure, Process Cost Report − LiDARs for Automotive and Industrial Applications 2018 – Market Technology Report − LiDAR for Automotive 2018 – Patent Landscape Analysis − MEMS Packaging 2017 – Market Technology Report − MEMS Packaging Comparison 2017 – Structure, Process Cost Report RF DEVICES ANDTECHNOLOGIES o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Wireless technologies (Radar, V2X) for Automotive 2018 − RF Standards and Technologies for Connected Objects 2018 − RF Photonic Components Technologies for 5G Infrastructure2018 o REVERSE COSTING® – STRUCTURE, PROCESS COST REPORT– by System Plus Consulting − Automotive Radar Comparison 2018 o PATENT ANALYSES – by KnowMade − RF Acoustic Wave Filters 2017 – Patent Landscape Analysis o LINKED REPORTS – by Yole Développement, System Plus Consulting andKnowMade − 5G impact on RF Front End Modules and Connectivity for Cellphones 2018 – Market Technology Report – Update − RF Front-End Module Comparison 2018 – Structure, Process Cost Report − RF Front End Modules for Cellphones 2018 – Patent Landscape Analysis − Advanced RF System-in-Package for Cellphones 2018 – Market Technology Report – Update* − Advanced RF SiPs for Cell Phones Comparison 2017 – Structure, Process Cost Report − RF GaN Market: Applications, Players, Technology, and Substrates 2018-2023 Market Technology Report – Update − RF GaN Comparison 2018* – Structure, Process Cost Report − RF GaN 2018 – Patent Landscape Analysis SOFTWARE o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Consumer Biometrics: Sensors Software 2018 – Update − Processing Hardware and Software for AI 2018 - Vol. 1 2 − From Image Processing to Deep Learning, Introduction to Hardware and Software Update : 2017 version still available / *To be confirmed
  • 34. 11©2018 | www.yole.fr | About Yole Développement OUR 2018 REPORTS COLLECTION (2/4) IMAGING OPTOELECTRONICS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of the Compact Camera Module and Wafer Level Optics − Industry 2018 – Update − 3D Imaging and Sensing 2018 – Update − Sensors for Robotic Vehicles 2018 − Machine Vision for Industry and Automation 2018 − Imagers and Detectors for Security and Smart Buildings 2018 − Uncooled Infrared Imagers 2017 o PATENT ANALYSES – by KnowMade − iPhone X Dot Projector – Patent-to-Product Mapping o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade − Status of the CMOS Image Sensor Industry 2018 – Market Technology Report - Update − CMOS Image Sensor Comparison 2018 – Structure, Process Cost Report − CMOS Image Sensors Monitor 2018* – Quaterly Update** − Camera Module 2017 – Market Technology Report − Compact Camera Module Comparison 2018 – Structure, Process Cost Report − LiDARs for Automotive and Industrial Applications 2018 – Market Technology Report − LiDAR for Automotive 2018 – Patent Landscape Analysis ADVANCED PACKAGING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of Advanced Packaging Industry 2018 – Update − Status of Advanced Substrates 2018: Embedded Die andInterconnects, Substrate Like PCB Trends − 3D TSV and Monolithic Business Update 2018 – Update − Power Modules Packaging 2018 – Update − Discrete Power Packaging 2018 – Update* − Status of Panel Level Packaging 2018 − Trends in Automotive Packaging 2018 − Hardware and Software for AI 2018 - Vol. 1 2 − Integrated Passive Devices (IPD) 2018 − Thin-Film Integrated Passive Devices 2018 − Memory Packaging Market and Technology Report 2018 – Update* o PATENT ANALYSES – by KnowMade − Hybrid Bonding for 3D Stack – Patent Landscape Analysis o LINKED REPORTS– by Yole Développement and System Plus Consulting − Advanced RF System-in-Package for Cellphones 2018 – Market Technology Report - Update* − Advanced RF SiPs for Cell Phones Comparison 2017 – Structure, Process Cost Report − Fan-Out Packaging 2018 – Market Technology Report – Update* − Fan-Out Packaging Comparison 2018* – Structure, Process Cost Report MANUFACTURING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Wafer Starts for More Than Moore Applications 2018 − Equipment for More than Moore: Technology Market Trends for Lithography Bonding/Debonding 2018 − Polymeric Materials for wafer-level Advanced Packaging 2018 − Laser Technologies for Semiconductor Manufacturing 2017 − Glass Substrate Manufacturing in the Semiconductor Field 2017 − Equipment and Materials for Fan-Out Packaging 2017 − Equipment and Materials for 3D TSV Applications 2017 o LINKED REPORTS – by Yole Développement and System Plus Consulting − Equipment for More than Moore: Technology Market Trends for Lithography Bonding/Debonding 2018 – Market Technology Report − Wafer Bonding Comparison2018 – Structure, Process Cost Report Update : 2017 version still available / *To be confirmed
  • 35. 12©2018 | www.yole.fr | About Yole Développement OUR 2018 REPORTS COLLECTION (3/4) MEMORY o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Emerging Non Volatile Memory 2018 – Update − Memory Packaging Market and Technology Report 2018 – Update* o QUARTERLY UPDATE – by Yole Développement** − Memory Market Monitor 2018 (NAND DRAM) o MONTHLY UPDATE – by Yole Développement** − Memory Pricing Monitor 2018 (NAND DRAM) o REVERSE ENGINEERING COSTING REVIEW – by System Plus Consulting − DRAM Technology Cost Review 2018 − NAND Memory Technology Cost Review 2018 o PATENT ANALYSES – by KnowMade − 3D Non-Volatile Memories – Patent Landscape COMPOUND SEMICONDUCTORS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of Compound Semiconductor Industry 2018* − GaAs Materials, Devices and Applications 2018 − InP Materials, Devices and Applications 2018 − Bulk GaN Substrate Market 2017 o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade − Power SiC 2018: Materials, Devices, and Applications – Market Technology Report – Update − SiC Transistor Comparison 2018 – Structure, Process Cost Report − Power SiC 2018 – Patent Landscape Analysis − Power GaN 2018: Materials, Devices, and Applications – Market Technology Report – Update − GaN-on-Silicon Transistor Comparison 2018 – Structure, Process Cost Report − Status of the GaN IP – Patent Watch 2018 Patent Activity 2017 − RF GaN Market: Applications, Players, Technology, and Substrates 2018-2023 – Market Technology Report – Update − RF GaN – Patent Landscape Analysis POWER ELECTRONICS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Status of Power Electronics Industry 2018 – Update − Discrete Power Packaging 2018 – Update* − Power Electronics for Electric Vehicles 2018 – Update − Integrated Passive Devices (IPD) 2018 − Wireless Charging Market Expectations and Technology Trends 2018 − Thermal Management Technology and Market Perspectives in Power − Electronics and LEDs 2017 − Gate Driver 2017 − Power MOSFET 2017 − IGBT 2017 − Market Opportunities for Thermal Management Components in Smartphones 2017 o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade − Power Modules Packaging 2018 – Market Technology Report – Update − Automotive Power Module Packaging Comparison2018 – Structure, Process Cost Report − Power ICs Market Monitor 2018 – Quaterly Update** − Power ICs Market Comparison 2018* – Structure, Process Cost Report BATTERY AND ENERGY MANAGEMENT o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Li-ion Battery Packs for Automotive and Stationary Storage Applications 2018 – Update o PATENT ANALYSES – by KnowMade − Status of the Battery Patents – Patent Watch 2018 Patent Activity 2017 o LINKED REPORTS – by Yole Développement and KnowMade − Solid State Electrolyte Battery 2018 – Market Technology Report − Solid-State Batteries 2018 – Patent Landscape Analysis Update : 2017 version still available / *To be confirmed / ** Can not be selected within an Annual Subscription offer
  • 36. 13©2018 | www.yole.fr | About Yole Développement OUR 2018 REPORTS COLLECTION (4/4) SOLID STATE LIGHTING o MARKET AND TECHNOLOGY REPORT – by Yole Développement − IR LEDs and Lasers 2018: Technology, Industry and Market Trends – Update − Automotive Lighting 2018: Technology, Industry and Market Trends – Update − UV LEDs 2018: Technology, Industry and Market Trends – Update − LiFi: Technology, Industry and Market Trends − LED Lighting Module Technology, Industry and Market Trends 2017 − CSP LED Lighting Modules − Phosphors Quantum Dots 2017 - LED Downconverters for Lighting Displays − Horticultural Lighting 2017 o LINKED REPORTS – by Yole Développement and System Plus Consulting − VCSELs 2018: Technology, Industry and Market Trends – Market Technology Report − VCSELs Comparison 2018 – Structure, Process Cost Report DISPLAYS o MARKET AND TECHNOLOGY REPORT – by Yole Développement − Quantum Dots and Wide Color Gamut Display Technologies 2018 – Update − Displays and Optical Vision Systems for VR/AR/MR 2018 − MicroLED Displays 2018 – Market Technology Report – Update o PATENT ANALYSES – by KnowMade − MicroLED Display – Patent Landscape Analysis MEDTECH o MARKET AND TECHNOLOGY REPORT – by Yole Développement − BioMEMS Non Invasive Emerging Biosensors: Microsystems for Medical − Applications 2018 – Update − Point-of-Need Testing Application of Microfluidic Technologies 2018 – Update − Neurotechnologies and Brain Computer Interface 2018 − CRISPR-Cas9 Technology: From Lab to Industries 2018 − Ultrasound technologies for Medical, Industrial and Consumer 2018 − Inkjet Functional and Additive Manufacturing for Electronics 2018 − Liquid Biopsy: from Isolation to Downstream Applications 2018 − Chinese Microfluidics Industry 2018 − Scientific Cameras for the Life Sciences Analytical Instrumentation Laboratory Markets 2018* − Artificial Organ Technology and Market 2017 − Connected Medical Devices Market and Business Models 2017 − Status of the Microfluidics Industry 2017 − Organs-On-Chips 2017 − Solid-State Medical Imaging 2017 − Medical Robotics Market Technology Analysis 2017 o PATENT ANALYSES – by KnowMade − Microfluidic IC Cooling – Patent Landscape − Circulating Tumor Cell Isolation – Patent Landscape − OCT Medical Imaging – Patent Landscape − Pumps for Microfluidic Devices – Patent Landscape 2017 − Microfluidic Technologies for Diagnostic Applications– Patent Landscape 2017 − FLUIDIGM – Patent Portfolio Analysis 2017 − Consumer Physics SCiO Molecular Sensor – Patent-to-Product Mapping 2017 o LINKED REPORTS – by Yole Développement, System Plus Consulting and KnowMade − Organs-On-Chips 2017 – Market Technology Report − Organ-on-a-Chip– Patent Landscape Analysis Update : 2017 version still available / *To be confirmed
  • 37. 14©2018 | www.yole.fr | About Yole Développement OUR 2017 PUBLISHED REPORTS LIST (3/3) OUR PARTNERS’ REPORTS PATENT ANALYSES – by KnowMade − Wireless Charging Patent LandscapeAnalysis − RF Acoustic Wave Filters Patent LandscapeAnalysis − NMC Lithium-Ion Batteries Patent LandscapeAnalysis − Pumps for Microfluidic Devices Patent Landscape − III-N PatentWatch − FLUIDIGM Patent Portfolio Analysis − Knowles MEMS Microphones in Apple iPhone 7 Plus Patent-to-Product Mapping 2017 − Consumer Physics SCiO Molecular Sensor Patent-to-Product Mapping − Patent Licensing Companies in the Semiconductor Market - Patent Litigation Risk and Potential Targets − Microfluidic Technologies for Diagnostic Applications Patent Landscape TEARDOWN REVERSE COSTING – by System Plus Consulting More than 60 teardowns and reverse costing analysis and cost simulation tools published in 2017 MORE INFORMATION o All the published reports from theYole Group of Companies are available on our website www.i-Micronews.com. o Ask for our Bundle Subscription offers: With our bundle offer, you choose the number of reports you are interested in and select the related offer. You then haveup to 12 months to select the required reports from the Yole Développement, System Plus Consulting and KnowMade offering. Pay once and receive the reports automatically (multi-user format). Contact your sales team according to your location (see the last slide).
  • 38. 15©2018 | www.yole.fr | About Yole Développement MICRONEWS MEDIA o About Micronews Media To meet the growing demand for market, technological and business information, Micronews Media integrates several tools able to reach each individual contact within its network.We will ensure you benefit from this. ON L IN E ON SITE IN PERSON @Micronews e-newsletter i-Micronews.com i-Micronewsjp.com FreeFullPDF.com Events Webcasts Unique, cost-effective ways to reach global audiences. Online display advertising campaigns are great strategies for improving your product/brand visibility.They are also an efficient way to adapt with the demands of the times and to evolve an effective marketing plan and strategy. Brand visibility,networking opportunities Today's technology makes it easy for us to communicate regularly, quickly,and inexpensively – but when understanding each other is critical, there is no substitute for meeting in-person.Events are the best way to exchange ideas with your customers, partners, prospects while increasing your brand/product visibility. Targeted audience involvement equals clear, concise perception of your company’s message. Webcasts are a smart, innovative way of communicating to a wider targeted audience.Webcasts create very useful,dynamic reference material for attendees and also for absentees, thanks to the recording technology. Benefit from the i-Micronews.com traffic generated by the 11,200+ monthly unique visitors, the 10,500+ weekly readers of @Micronew se-newsletter Several key events planned for 2018 on different topics to attract 120 attendees on average Gain new leads for your business from an average of 340 registrants per webcast Contact: Camille Veyrier (veyrier@yole.fr),Marketing Communication Project Manager
  • 39. 16©2018 | www.yole.fr | About Yole Développement CONTACT INFORMATION o CONSULTINGANDSPECIFICANALYSIS,REPORT BUSINESS • North America: • Steve LaFerriere, Senior Sales Director for Western US Canada Email: laferriere@yole.fr – + 1 310 600-8267 • Troy Blanchette, Senior Sales Director for Eastern US Canada Email: troy.blanchette@yole.fr – +1 704 859-0453 • Japan Rest ofAsia: • Takashi Onozawa, General Manager,Asia Business Development (Korea, Singapore, India ROA) Email: onozawa@yole.fr - +81 34405-9204 • Miho Othake, Account Manager (Japan) Email: ohtake@yole.fr - +81 3 4405 9204 • Itsuyo Oshiba, Account Manager (Japan) Email: oshiba@yole.fr - +81-80-3577-3042 • Greater China: MavisWang, Director of Greater China Business Development Email: wang@yole.fr - +886 979 336 809 • Europe: Lizzie Levenez,EMEA Business Development Manager Email: levenez@yole.fr - +49 15 123 544 182 • RoW: Jean-Christophe Eloy,CEO President,Yole Développement Email eloy@yole.fr - +33 4 72 83 01 80 o FINANCIAL SERVICES (in partnershipwithWoodside CapitalPartners) • Jean-Christophe Eloy,CEO President Email: eloy@yole.fr - +33 4 72 83 01 80 • Ivan Donaldson,VP of Financial Market Development Email: ivan.donaldson@yole.fr - +1 208 850 3914 o GENERAL • Public Relations: leroy@yole.fr - +33 4 72 83 01 89 • Email: info@yole.fr - +33 4 72 83 01 80 Follow us on