Mechanical thrombectomy is a minimally invasive procedure to remove blood clots from large brain vessels. It involves inserting a catheter through a small groin incision and using stent-like devices to remove clots causing acute ischemic strokes from large artery occlusion. It can benefit patients who are not candidates for or failed intravenous thrombolysis, especially if performed within 24 hours of symptom onset. Recovery depends on patient factors but may take weeks, with potential for improved outcomes over intravenous thrombolysis alone.