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PHARMACIST
Diabetes Mellitus
A group of diseases
characterized by high
levels of blood glucose
resulting from defects in
insulin production, insulin
action, or both
TYPES
OF
DIABETES
MELLITUS
TYPE-1 DIABETIS MELLITUS
TYPE-2 DIABETIS MELLITUS
GESTATIONAL DIABETIS
Body does not produce
enough insulin
Body produces insulin
but can’t use it well
A temporary condition in
pregnancy
After 40 Before 30
EVERY
1 PERSON
IN 11
SUFFERS
FROM
DIABETE
ITS MORE LETHAL THAN AIDS, TUBERCLOSIS AND MALARIA
Number Of Deaths Due To Various Diseases
5.0 Million
Diabetes
1.5 Million
AIDS
1.5 Million
Tuberculosis
0.6 Million
Malaria
According to the Lancet
study, China, India and
USA are among the top
three countries with a high
number of diabetic
population.
India had 69.2 million people living
with diabetes (8.7%) as per the
2015 data. Of these, it remained
undiagnosed in more than 36
million people.
Stroke
Amputation
Kidney Failure
Heart Attack
Blindness
DIABETES
can lead to
complications
of many parts
of body
ROLE OF
PHARMACIST
Starts
Here
 The major components of the treatment of diabetes are:
• Diet and ExerciseA
• Oral hypoglycaemic
therapyB
• Insulin TherapyC
Management of DM
Be
on
the
Right
TRACK
Diabetes – Oral Medications
6 Classes :
• Sulfonylureas stimulate β cells
• Biguanides improves insulin’s ability to move glucose
• Sulfonylureas and biguanide combination drugs
BOTH
• Thiazolidinediones cells more sensitive to insulin
• Alpha-glycosidase inhibitors Block enzymes that help digest
starches
• Meglitinides stimulate β cells (dependant upon glucose conc.)
Insulin therapy
Recent advancement
IDENTIFY PERSONS WHO ARE AT A HIGH RISK
Persons Who
Are At High
Risk Of
Developing
Diabetes May
Be
Junk
Foodies
Obese
People
Physically
Inactive
Persons
With
Family
History
Smokers
ADVICE PREVENTIONS TO AVOID DIABETES
TO EAT HEALTHY
TO BE PHYSICALLY ACTIVE
TO AVOID EXCESSIVE WEIGHT GAIN
MANAGING THE DIABETES
DRUG TREATMENT OR INSULIN THERAPY
REGULAR CHECKUP OF BLOOD GLUCOSE
HEALTHY FOOD AND DAILY EXERCISE
CONCLUSION
• Counselling
• Self monitoring of patients
• Side effects of drugs
• Do not self medicate
• Do not miss the dose
Educate the Patient
When ‘i’ is replaced By ‘we’
Even
‘illness’
Becomes
‘wellness’
REFERENCES
1. Renuka C. P. et.al (2002) J. Biol. Chem. 277, 22590–4.
2. Zoltan V. AND William C. D. (2001) Pharm. Rev. 52, 1-9.
3. Lauge S. et. Al (2003) PNAS 100, 4435-9.
4. Mark R. B. (1997) J. of Clin. Endoc.& Met. 82, 3-7.
5. Gianni C. (1992) FEBS 307, 66-70.
6. Irl B. H., (2001) Clin. Diabetes 19, 146-7.
7. BRUCE W. B. and POUL S. (2001) Diabetes care 24,69-
72.
8. http://www.indstate.edu/thcme/mwking/diabetes.html.
References
Thank You

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role of pharmacist in maintainance of diabetis

  • 2. Diabetes Mellitus A group of diseases characterized by high levels of blood glucose resulting from defects in insulin production, insulin action, or both
  • 3. TYPES OF DIABETES MELLITUS TYPE-1 DIABETIS MELLITUS TYPE-2 DIABETIS MELLITUS GESTATIONAL DIABETIS Body does not produce enough insulin Body produces insulin but can’t use it well A temporary condition in pregnancy
  • 6. ITS MORE LETHAL THAN AIDS, TUBERCLOSIS AND MALARIA Number Of Deaths Due To Various Diseases 5.0 Million Diabetes 1.5 Million AIDS 1.5 Million Tuberculosis 0.6 Million Malaria
  • 7. According to the Lancet study, China, India and USA are among the top three countries with a high number of diabetic population. India had 69.2 million people living with diabetes (8.7%) as per the 2015 data. Of these, it remained undiagnosed in more than 36 million people.
  • 8. Stroke Amputation Kidney Failure Heart Attack Blindness DIABETES can lead to complications of many parts of body
  • 10.  The major components of the treatment of diabetes are: • Diet and ExerciseA • Oral hypoglycaemic therapyB • Insulin TherapyC Management of DM
  • 12. Diabetes – Oral Medications 6 Classes : • Sulfonylureas stimulate β cells • Biguanides improves insulin’s ability to move glucose • Sulfonylureas and biguanide combination drugs BOTH • Thiazolidinediones cells more sensitive to insulin • Alpha-glycosidase inhibitors Block enzymes that help digest starches • Meglitinides stimulate β cells (dependant upon glucose conc.)
  • 14. IDENTIFY PERSONS WHO ARE AT A HIGH RISK Persons Who Are At High Risk Of Developing Diabetes May Be Junk Foodies Obese People Physically Inactive Persons With Family History Smokers
  • 15. ADVICE PREVENTIONS TO AVOID DIABETES TO EAT HEALTHY TO BE PHYSICALLY ACTIVE TO AVOID EXCESSIVE WEIGHT GAIN
  • 16. MANAGING THE DIABETES DRUG TREATMENT OR INSULIN THERAPY REGULAR CHECKUP OF BLOOD GLUCOSE HEALTHY FOOD AND DAILY EXERCISE
  • 17. CONCLUSION • Counselling • Self monitoring of patients • Side effects of drugs • Do not self medicate • Do not miss the dose Educate the Patient
  • 18. When ‘i’ is replaced By ‘we’ Even ‘illness’ Becomes ‘wellness’
  • 19. REFERENCES 1. Renuka C. P. et.al (2002) J. Biol. Chem. 277, 22590–4. 2. Zoltan V. AND William C. D. (2001) Pharm. Rev. 52, 1-9. 3. Lauge S. et. Al (2003) PNAS 100, 4435-9. 4. Mark R. B. (1997) J. of Clin. Endoc.& Met. 82, 3-7. 5. Gianni C. (1992) FEBS 307, 66-70. 6. Irl B. H., (2001) Clin. Diabetes 19, 146-7. 7. BRUCE W. B. and POUL S. (2001) Diabetes care 24,69- 72. 8. http://www.indstate.edu/thcme/mwking/diabetes.html. References