Coplin_CV_05.06.2015

COPLIN_CV_05.06.2015
Updated: 6 May 2015
__________________________
Signature
WILLIAM M. COPLIN, MD, FCCM, FNCS
Address: 1245 Humboldt St. - #208, Denver, CO 80218
Telephone: (313) 702-2202
E-mails: wmcoplin@gmail.com
EDUCATION
Medical: Baylor College of Medicine, Houston, TX, MD May 1989
Baccalaureate: University of Chicago, IL, AB, Biological Sciences June 1985
Other: University of Alabama, Birmingham, Physics, Summer 1983
Other: Cornell University, Ithaca, NY, Biology, Summer 1980
DATES
1985-1989
1981-1985
1983
1980
POSTGRADUATE TRAINING
Fellowships: University of Washington, Seattle
Senior Fellow, Department of Neurological Surgery (Critical Care)
Senior Fellow, Division of Pulmonary & Critical Care Medicine
Residency: University of Washington, Seattle, Neurology
Internship: University of Washington, Seattle, Internal Medicine
1995-1996
1994-1996
1990-1993
1989-1990
FACULTY APPOINTMENTS
Associate Professor, Departments of Neurology & Neurological Surgery, Wayne
State University, Detroit, MI
Assistant Professor, Neurological Surgery, Wayne State University, Detroit, MI
Assistant Professor, Neurology, Wayne State University, Detroit, MI
Acting Instructor, Neurology/Medicine, University of Washington, Seattle
2001-2012
1996-2001
1996-2001
1993-1996
HOSPITAL OR OTHER PROFESSIONAL APPOINTMENTS
Trauma Performance Improvement Patient Safety Committees, Penrose Hospital,
Colorado Springs, CO
Stroke Excellence Committee, Penrose-St. Francis Health Services, Colorado
Springs, CO
Medical Staff, Penrose Hospital, Colorado Springs, CO
Medical Staff, St. Mary-Corwin Hospital, Pueblo, CO
Neurocritical Care & Neurosciences Medical Director, Neurosciences System of
Care, Centura Health, Englewood CO
Neurosciences Council (co-chair) Centura Health, Englewood, CO
Spine Council (co-chair), Centura Health, Englewood, CO
Trauma Council (ad hoc), Centura Health, Englewood, CO
Growth & Innovation Committee, Centura Health, Englewood, CO
Clinical Improvement Steering Committee (invited guest, ad hoc), Centura Health,
Englewood, CO
Physician Champion, System Stroke Coordinators, Centura Health, Englewood,
CO
Level-One Trauma, Trauma Morbidity and Mortality, and Trauma Quality
Improvement Operations Committees, St. Anthony Hospital, Lakewood, CO
Pharmacy & Therapeutics Committee, St. Anthony Hospital, Lakewood, CO
2014-2015
2014-2015
2014-2015
2014-2015
2013-2015
2013-2015
2013-2015
2013-2015
2013-2014
2013-2015
2013-2015
2013-2015
2013-2015

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2
Critical Care Practice Council, St. Anthony Hospital, Lakewood, CO
Stroke/Neuroscience Peer Review Committee, St. Anthony Hospital, Lakewood,
CO
Director, Neurocritical Care, St. Anthony Hospital, Lakewood, CO
Medical Staff, St. Anthony Hospital, Lakewood, CO
Comprehensive Stroke Research Committee, Penrose Hospital, Colorado Springs,
CO
Neurosciences Committee, Littleton Adventist Hospital, Littleton, CO
Trauma Committee (ad hoc), Littleton Adventist Hospital, Littleton, CO
Neurosciences Committee, Parker Adventist Hospital, Parker, CO
Spine Committee, Parker Adventist Hospital, Parker, CO
Trauma Committee (ad hoc), St. Mary-Corwin Hospital, Pueblo, CO
TBI Committee, St. Anthony Summit Medical Center, Frisco, CO
Resuscitation Committee, Detroit Medical Center hospitals, MI
System-Wide Stroke Committee, Detroit Medical Center hospitals, MI
System-Wide Critical Care Committee, Detroit Medical Center hospitals, MI
Pharmacy and Therapeutics Committee, Detroit Medical Center hospitals, MI
Chief of Neurology, Detroit Receiving Hospital, MI
Medical Director, Neurotrauma & Critical Care, Detroit Receiving Hospital, MI
Ethics Committee, Detroit Receiving Hospital, MI
Physician Champion, Organ Donation Protocol Committee, Detroit Receiving
Hospital, MI
Program Director, Neurotrauma and Neurocritical Care Fellowships, Wayne State
University/Detroit Medical Center, MI
Level-One Trauma and Trauma Morbidity and Mortality Committees, Detroit
Receiving Hospital, MI
Special Care Committee, Detroit Receiving Hospital, MI
Medical Staff, Detroit Receiving Hospital/Detroit Medical Center hospitals, MI
2013-2015
2013-2015
2013-2014
2013-2015
2013-2015
2013-2015
2013-2015
2013-2015
2013-2015
2013-2015
2013-2015
2010-2012
2009-2012
2009-2012
1999-2012
1999-2011
1998-2011
1998-2012
1998-2012
1997-2011
1996-2012
1996-2012
1996-2012
MAJOR PROFESSIONAL SOCIETIES
Neurocritical Care Society – Founding Board Member (inception-2013;
http://www.neurocriticalcare.org/about-us/history); initial Co-Chair, Long-Range
Planning Committee (past); Annual Meeting Committee (past); External
Ventricular Drain Guidelines Committee (current); Co-Chair, Emergency
Neurological Life Support Certification Subcommittee (current)
American Neurological Association
American Stroke Association/American Heart Association – Stroke Council
American Association of Neurological Surgeons – Executive Committee, Joint Section on
Neurotrauma & Critical Care (2000-present)
Congress of Neurological Surgeons – Executive Committee, Joint Section on
Neurotrauma & Critical Care (2000-present)
Society of Critical Care Medicine – Past Chair, Neuroscience Section (2004-2006);
Program Planning Committee (2004-2009); Course Director, Neurocritical Care
(2005-2009); Sedation and Analgesia Practice Parameters Committee (1998-2010)
American Academy of Neurology – Past Chair, Critical Care and Emergency Neurology
1999-present
~2000-2011
~1997-present
~1996-present
~1996-present
~1994-present
~1990-present

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3
Section (2005-2007); Executive Committee, Critical Care and Emergency
Neurology Section (2007-2009); Course Director, Neurotrauma Course (past)
MEDICAL LICENSURE
Colorado DR.0053222 (11/25/2013 – 4/30/2015)
Michigan 4301068197 (5/22/1996 – 1/31/2015)
Washington MD00028748 (expired 2/7/97)
BOARD CERTIFICATION
FLEX (630207004, 12/1990)
Neurology (expires 3/2018)
Neurocritical Care (expires 12/2020)
Advanced Cardiac Life Support
Advanced Trauma Life Support – Instructor
Emergency Neurological Life Support - Instructor
HONORS/AWARDS
Best Attending Physician (Nursing), Detroit Receiving Hospital
Neurology Residents’ Teaching Award, Wayne State University
Presidential Citations, Society of Critical Care Medicine
School of Medicine Teaching Award, Wayne State University
Joseph F. Dasta Pharmacy Research Award (with Denise H Rhoney, PharmD),
Society of Critical Care Medicine
Nursing Research Award, Society of Critical Care Medicine
2010-2011
2008-2009
1999, 2007
2003-2004
2003
2000
SERVICE
Centura Health
Neurotrauma & Neurocritical Care, Acute Stroke Team, Neurology
inpatient service – on-call emergency and inpatient coverage and consultative coverage
and availability
St. Anthony Hospital, Penrose Hospital, St. Francis Medical Center
Neurocritical Care, Neurotrauma, Acute Stroke Team, Neurology, and
Neurosurgery – consultative and clinical guidance availability, case reviews
Centura Health Neurosciences System of Care (15 hospitals and 9
affiliates)
Centura Health Neuroscience System of Care (SOC) Accomplishments
Ø Neuroscience SOC Redefined and updated to include all neurology,
neurological surgery and some psychiatry, otolaryngology, and physical
medicine & rehabilitation diagnoses
Ø Neuroscience disease-based database constructed
Ø Centura regained top market share for stroke and TIA
Ø Centura Health Physician Group neuro-interventionalists joined to cross-
cover multiple facilities
Ø St. Anthony Hospital achieved Joint Commission (TJC) Comprehensive
Stroke Center certification
Ø Avista Adventist and St. Catherine’s hospitals achieved TJC Primary Stroke
Center certification
Ø Avista Adventist and St. Anthony North hospitals obtained fulltime
neurology acute care coverage
2013-2015
2013-2015
2013-2015

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4
Ø Avista Adventist Hospital achieved TJC Spine Certification
Ø Neuroscience-specific outreach and provider/staff education established
(over 102 encounters)
Ø Littleton Adventist Hospital (LAH) opened Centura’s first Epilepsy
Monitoring Unit (EMU)
Ø LAH performed the world’s first asleep Deep Brain Stimulation (DBS)
surgery with the Mazor® Robotic Guidance System
Ø Centura became the US’s first healthcare system to partner (with
CortiCare®) in continuous EEG cloud monitoring
Ø Two research studies with platform presentations at the International
Stroke Conference; won “best of” honors for representation at American
Heart Association Annual Sessions National Meeting
Ø One abstract accepted and presented at the Society of Critical Care
Medicine
Ø National presentation at Society of Interventional Neurology Annual
Meeting (Ms. Santos, System VP Neuroscience & administrative dyad
partner)
Ø System-wide standardization for swallow screen, stroke patient and family
education, and stroke order sets
Ø System-wide standardization for Triage Back Pain Protocol
Ø System guidelines of care and order set standardization for Therapeutic
Temperature Management after Cardiac Arrest, Spinal Cord Injury, Severe
Traumatic Brain Injury
Wayne State University
Clinical
Neurotrauma & Neurocritical Care inpatient services – shared duty,
continual availability
Detroit Receiving, Harper, Sinai-Grace, Hutzel, and Children’s hospitals
Acute stroke team – shared duties for continuous coverage
Detroit Receiving, Harper, Sinai-Grace, Huron Valley, and Children’s
hospitals; Michigan Stroke Network
Neurology inpatient service – ad hoc ward coverage
Detroit Receiving Hospital
Neurotrauma, Stroke, Neurocritical Care, Pulmonary & Critical Care,
Trauma Surgery, and Burn Surgery fellows – supervision and training
Neurology, Neurological Surgery, Emergency Medicine, Physical
Medicine & Rehabilitation residents – supervision and training
Departmental/Divisional
Department of Neurology Internal Review Committee
Department of Neurological Surgery Internal Review Committee
Fellowship Director, Neurotrauma and Neurocritical Care Fellowships
School of Medicine
Emergency Medicine Chair Search Committee
Pediatrics Chair Search Committee
1996-2011
1997-2011
1996-2011
1996-2011
1996-2011
1997-2011
Professional (e.g., other medical or scientific organizations and societies)
April 1997 - 2003
American Academy of Neurology Critical Care and Emergency Neurology Section
Credentialing Committee

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5
February 1998 - 2011
NACABI Intraventricular Thrombolysis Trial
Executive Committee
December 1998 – 2010
Sedation and Analgesia Practice Parameters Committee
February 2000 – January 2002
Neurosciences Section, Secretary/Treasurer
May 2000 – May 2008
Interventional Management of Stroke clinical trial
Steering Committee
Fall 2000 - Present
AANS/CNS Joint Section on Neurotrauma and Critical Care
Executive Committee – Critical Care and Neurocritical Care liaison
Spring 2001 – Spring 2009
American Academy of Neurology Section on Emergency and Critical Care
Executive Committee
January 2002 – 2004
Neurosciences Section, Chair-Elect
August 2002 – September 2014
Neurocritical Care Society
Board of Directors, founding member
January 2004 – Present
Neurosciences Section, Chair
January 2002 – 2004
AANS/Brain Trauma Foundation
Guidelines for the Management of Severe Traumatic Brain Injury Committee
November 2012 – Present
Brain Death Subcommittee of NCS Ethics Committee
External Ventricular Drains Guidelines Committee and co-author

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6
Emergency Neurological Life Support Subcommittee on Certification, Co-Chair
Community (e.g., presentations for lay audiences, educational outreach, media
presentations/interviews)
News service interviews: Traumatic brain injury, stroke, and
hemicraniectomy, hypothermia: MSNBC et al.
Michigan Stroke Initiative, Enhancing Access to Acute Stroke Care in
Michigan Communities, 1999-2011
Great Lakes Transplantation Association, medical advisory board, 1999-
2011
Wayne County Traffic Safety Commission, 2000-2011
Community Stroke education, Detroit, MI
Community Education and Feedback for Waiver of Informed Consent for
Hemicraniectomy clinical trial, Detroit, MI
Brain Injury Association of Michigan
Brain Injury Association of Colorado, May 2014
Online Live Chat – Stroke Prevention – Centura Health, May 2013
Centura Health Neurosciences System of Care, Affiliate, Critical Access and
Community Outreach, May 2013-January 2015 (* = multiple) – includes
presentations, clinical and didactic education, case reviews, etc
Cheyenne Regional Medical Center, Cheyenne, WY
Denver Health Medical Center, Denver, CO
Aspen Valley Hospital, Aspen, CO
St. Vincent’s Hospital, Leadville, CO*
Longmont United Hospital, Longmont, CO*
Platte Valley Medical Center, Brighton, CO*
Good Samaritan Medical Center, Lafayette, CO
Heart of The Rockies Regional Medical Center, Salida, CO*
San Luis Valley Regional Medical Center, Alamosa, CO*
Rio Grande Hospital, Del Norte, CO*
Conejos County Hospital, La Jara, CO
Pagosa Springs Medical Center, Pagosa Springs, CO*
San Juan Regional Medical Center, Farmington, NM
Southwest Memorial Hospital, Cortez, CO
Lincoln Community Hospital, Hugo, CO
Miners’ Colfax Medical Center, Raton, NM
Kit Carson County Memorial Hospital, Burlington, CO
Goodland Regional Medical Center, Goodland, KS
Consulting
Remifentanil Advisory Board, Glaxo-Wellcome, February 1998

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7
Tirilazad Mesylate in SAH advisory panel, Pharmacia & Upjohn, April 1999
Innercool Therapies, Stroke Initiative, April 2000
Medivance Hypothermia Panel/Arctic Circle, Feb. 2002 – 2011
Integra Neurosciences, 2002 – Present
Ortho-McNeil, 2003 – 2008
ESP Pharma, 2003 – 2005
PDL Biopharma, 2005-2008
UCB Pharma, 2015 – Present
Bard Medical, 2015 – Present
Multiple investment banking organizations
Scholarly Service
Grant Review Committees
National
June 1999 - 2005
NIH/NINDS - Member
Cell Death and Injury in Neurodegeneration Study Section (formerly
Brain Disorders and Clinical Neurosciences –3)
NIH/NINDS: Clinical Trials Study Group – Ad hoc
Regional/Local
Rehabilitation Institute of Michigan internal grant reviews – last 2011
Service for Peer-Reviewed Journals
Editorial Board Membership – Neurocritical Care
Review of Manuscripts – ad hoc reviews for Neurosurgery, Journal of the
Neurological Sciences, American Journal of Kidney Diseases, Respiratory
Care, Neurology, Stroke, Archives of Neurology, Cerebrovascular
Diseases, New England Journal of Medicine, Journal of Stroke and
Cerebrovascular Diseases, Annals of Neurology, Journal of Neuroimaging,
Critical Care, and Critical Care Medicine
Moderator for numerous scientific sessions, e.g., Rocky Mountain
Neurocritical Care Conference, Denver, 2013 (Course Director); Neurocritical
Care Society; Society of Critical Care Medicine (Course Director, Neurocritical

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8
Care); American Academy of Neurology (Course director, Neurotrauma, 2002-
2003); International Neurocritical Care Symposia – Panama; IInd National
Workshop – Critical Care Neurology, Hyderabad, India (Course Director,
Critical Care Neurology, 2003)
OTHER SERVICE DATES
TEACHING
Centura Health Neurosciences System of Care, Centura Health Hospital Affiliates,
Colorado Critical Access Hospital Outreach
Undergraduate students
Bedside rounding
Nursing and Respiratory Therapy
Medical students
Bedside rounding
Rocky Vista University College of Osteopathic Medicine
Residents/Fellows
Bedside rounding and didactic (see didactic below)
St. Anthony Hospital Surgical residents
University of Colorado Pulmonary & Critical Care Medicine fellows
Physicians/Nurses/Pharmacists (CME/CEU/CE)
Bedside/clinical rounds; didactics; case reviews for Neurology, Stroke/ICH/SAH,
Neurosurgery, Trauma, Neuroradiology, Skull-Base Surgery/Otolaryngology/Head &
Neck Surgery, and Emergency Medicine; also see Invited Lectures/Presentations
Wayne State University
Teaching at Wayne State University
Under the categories below, list course number/title or type of teaching activity and your role.
Indicate year(s) when taught.
Undergraduate students
Shadowing elective in Neurology/Neuro-Emergencies/Neurocritical
Care/Neurotrauma for high school and Wayne State University college students
Graduate students
School of Pharmacy Students – regular rotation through NeuroICU
Shadowing elective for Wayne State University Law School students
Neuropsychology resident and fellow didactics – traumatic brain injury
Certified Registered Nurse Anesthetist students
Lectures - airway management and ventilation of the brain-injured
Clinical Preceptorship – neuroemergencies, neurotrauma, and neurocritical care
2013-2015
1996-2012

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9
Advanced Cinical Nurse Practitioner students
Clinical Preceptorship - neuroemergencies, neurotrauma, and neurocritical care
Medical students
Year Two – lectures and small group didactic sessions
Neuropathophysiology course
Objective Structured Clinical Exam
Neurology Clinical Vignettes
Year Three – attending physician for Neurocritical Care/Neurology clinical rotation –
included didactic core lectures
Year Four – elective clinical attending and preceptorships in Neurocritical Care,
Neurology, Stroke/Vascular Neurology, Neurological Surgery, Critical Care Medicine,
Trauma Surgery, and Emergency Medicine – included didactic lectures
Residents/Fellows
Neurology Residents – rounding attending physician (NeuroICU and ward services),
mentoring, didactic lectures
Neurology Resident Teaching Conference
Neurology Journal Club
Neurology Professor’s Rounds
Stroke Conference
Neurological Surgery Residents – rounding attending physician, (NeuroICU and ward
services), mentoring, didactic lectures
Neurosurgery Resident Core Lectures
Neurosurgery Journal Club
Neurotrauma Conference
Emergency Medicine Residents – rounding attending physician (1st
-year NeuroICU
rotation and Senior Resident electives), mentoring, didactic lectures
Pharmacy Practice Residents -- rounding attending physician (NeuroICU rotation),
research mentoring, didactic lectures
General Surgery Residents – rounding consulting physician, mentoring
Trauma Conference
Internal Medicine Residents’ board review - Neurology
Physical Medicine & Rehabilitation Residents – NeuroICU elective rounding attending
physician, mentoring, didactic lectures
Physical Medicine & Rehabilitation Lecture Series
Neurotrauma Fellows – Program Director, rounding attending physician, research
Neurocritical Care Fellows -- Program Director, rounding attending physician, research

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10
Pulmonary & Critical Care Medicine Fellows – rounding attending physician
(scheduled Neurocritical Care rotation and electives), mentoring, didactic lectures
Core Lectures
Fundamentals in Critical Care Support Course – Neurologic Assessment and Support
Emergency Medicine Critical Care Fellows -- rounding attending physician, mentoring,
didactic lectures
Trauma Surgery Fellows -- rounding attending physician (scheduled
Neurotrauma/Neurocritical Care rotation and elective), mentoring, didactic lectures
Burn Surgery Fellows – rounding attending physician (elective Neurocritical Care
rotation), mentoring, didactic lectures
Didactics; case reviews for Neurology, Stroke/ICH/SAH, Neurosurgery, Trauma,
Neuroradiology, and Emergency Medicine; also see Invited Lectures/Presentations
Nutritionist/dietician didactics
Speech and Language Therapy didactics
Faculty (CME)
University of Washington
Graduate Professional students
Law B520 (Trial Advocacy)
Medical students
Human Biology 550 (Basic Neurology)
Medicine 686 (Neurology Clerkship)
Human Biology 541 (The Respiratory System)
Residents/Fellows
Neurology Resident Teaching Conferences
Neurology Journal Club
Neurological Surgery Resident Teaching Conference
Respiratory/Critical Care Conference
VA Chief of Medicine Rounds
VA Medicine Noon Conferences
University of Washington Medicine Noon Conferences
Swedish Hospital Medicine Noon Conferences
Swedish Hospital Medicine Morning Report
Neurology, Neurological Surgery, Pulmonary & Critical Care Medicine Grand Rounds
and conferences and didactics - also see Invited Lectures/Presentations
1993-1996
1995
1993-1996
1993-1996
1995
1993-1996
1993-1996

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Mentorship
Multiple medical, pharmacy, nurse anesthetist, acute care nurse practitioner, and dietician
students and residents
Faith Abbott, DO, neurotrauma fellow
Prasad Policherla, MD, neurotrauma and neurocritical care fellow
Rodney Leacock, MD, neurotrauma and neurocritical care fellow
Jacqueline Kraus, MD, neurotrauma and neurocritical care fellow
Gregory Norris, MD, neurotrauma and neurocritical care fellow
Ahmed Abdulsalam, MD, neurocritical care fellow
Benjamin Atkinson, MD, neurotrauma and neurocritical care fellow
Theses/Dissertations mentoring assistance – Wayne State University
Bill D. Underwood, MD, PhD, clinical and editorial, heat shock protein and other gene
expression after penetrating traumatic brain injury
Julie G. Pilitsis, MD, PhD, clinical and editorial, central nervous system free fatty acid
metabolism and disposition after acute brain injury
John J. Steele III, MD, PhD, clinical and editorial, electrophysiological alterations and
topography after acute brain injury
Course and curriculum development
§ Refining Skills in Nutrition Support (Educational Planning Committee) 1999
§ Critical Care Neurology (IInd National Workshop – Critical Care Neurology,
Hyderabad, India) 2003
§ Neurotrauma (American Academy of Neurology) 2002 & 2003
§ Neurocritical Care (Society of Critical Care Medicine) 2005-2009
§ Neurocritical Care in Catastrophic Conditions (Neurocritical Care Society) 2011
§ Rocky Mountain Neurocritical Care Conference (Centura Health) 2013
1995
1995-1996
1993-1995
1993-1995
1993-1995
1993-1994
1993-1994
1993-1996
1996-2011
GRANTS, CONTRACTS, AND OTHER FUNDING
Active and Pending Grants and Contracts
None
Previously funded NIH Grant as PI
NIH/NINDS 1 RO1 NS38905-01, Early hemicraniectomy to manage traumatic brain
injury. 7/16/99 – 6/30/03, $260,606
Previously submitted, not funded Grants and Contracts as PI
NIH/NINDS 1 R21 NS048744-01, IntraCranial Pressure Prevention and Control
Investigation. (Coplin)
1999-2003
CLINICAL TRIALS ACTIVITIES
Within last two years:
• A Non-Transfer Protocol for Patients with Stable, Mild, Isolated Traumatic Brain Injury at
Level III and IV Trauma Centers, co-PI
• Neurotelemetry: Remote cEEG Monitoring and Reading for Neurocritical Care Patient
Management, co-PI and abstract presenter
• Boehringer-Ingelheim 1160.189 (ESUS study), local PI – while at Centura Health
• POINT, co-investigator – while at Centura Health

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• Association Between Pharmacological Thromboprophylaxis And Hemorrhage Progression In
Patients With Hemorrhagic Stroke, co-investigator, abstract presenter, and lead author for
manuscript in progress
• Pharmacological Thromboprophylaxis Reduces the Odds of Venous Thromboembolism In
Patients With Hemorrhagic Stroke, co-investigator, abstract presenter, and lead author for
manuscript in progress
PUBLICATIONS
• Recent and representative publications in journals (selected from > 69). Does not include presentations, abstracts,
book chapters, or articles ‘in preparation’ or ‘submitted.’
Chesnut, R, et al. A Consensus-based Guide to the Interpretation of the BEST TRIP ICP Trial. J
Neurotrauma. 2015;in press
Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, et al. Very early
administration of progesterone for acute traumatic brain injury. N Engl J Med. 2014;371(26):2457-
66.
Frank JI, Schumm LP, Wroblewski K, Chyatte D, Rosengart AJ, Kordeck C, et al. Hemicraniectomy
and durotomy upon deterioration from infarction-related swelling trial: randomized pilot clinical
trial. Stroke. 2014;45(3):781-7.
Levy AS, Salottolo K, Coplin WM, Smith R, Santos P, Bar-Or D. Pharmocologic
thromboprophylaxis reduces the odds of venous thromboembolism in patients with hemorrhagic
stroke. Stroke. 2014 – presented at 2014 International Stroke Conference, San Diego
Levy AS, Salottolo K, Coplin WM, Orlando A, Smith R, Santos P, Bar-Or D. Association between
pharmacologic thromboprophylaxis and hemorrhage progression in patients with hemorrhagic
stroke. Stroke. 2014 – presented at 2014 International Stroke Conference, San Diego
Coplin WM. Traumatic spinal cord injury. In: NCS Practice Update Textbook, Neurocritical Care
Society, 2014.
Liu-DeRyke X, Levy PD, Parker D Jr, Coplin W, Rhoney DH. A prospective evaluation of labetalol
versus nicardipine for blood pressure management in patients with acute stroke. Neurocrit Care.
2013;19:41-7.
Bhattacharya P, Kansara A, Chaturvedi S, Coplin W. What drives the increasing utilisation of
hemicraniectomy in acute ischaemic stroke? J Neurol Neurosurg Psychiatry. 2013; 84(7):727-31.
Nagaraja N, Bhattacharya P, Norris G, Coplin W, Narayanan S, Xavier A, et al. Arrival by
ambulance is associated with acute stroke intervention in young adults. J Neurol Sci. 2012;316(1-
2):168-9.
Coplin WM. Critical care management of acute ischemic stroke. Neurology. Continuum (Minneap
Minn). 2012;18(3):547-59.
Naff N, Williams MA, Keyl PM, Tuhrim S, Bullock MR, Mayer SA, et al. Low-dose recombinant
tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular
hemorrhage thrombolysis trial. Stroke. 2011;42(11):3009-16.

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13
Kullar R, Chin JN, Edwards DJ, Parker D, Coplin WM, Rybak MJ. Pharmacokinetics of single-dose
daptomycin in patients with suspected or confirmed neurological infections. Antimicrob Agents
Chemother. 2011;55(7):3505-9.
Rhoney DH, Coplin WM, Lin Y, Frankel M, Lyden PD, Levine SR. Time of day, outcome, and
response to thrombolytic therapy: the National Institute of Neurological Disorders and Stroke
Recombinant Tissue Plasminogen Activator Stroke Trial experience. J Stroke Cerebrovasc Dis.
2010;19(1):40-8.
Browning L, Parker D, Jr., Liu-DeRyke X, Shah A, Coplin WM, Rhoney DH. Possible removal of
topiramate by continuous renal replacement therapy. J Neurol Sci. 2010;288(1-2):186-9.
Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, et al. Effect of
prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with
Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical
trial. Stroke. 2008;39(6):1759-65.
Ramappa P, Thatai D, Coplin W, Gellman S, Carhuapoma JR, Quah R, et al. Cardiac troponin-I: a
predictor of prognosis in subarachnoid hemorrhage. Neurocrit Care. 2008;8(3):398-403.
Liu-Deryke X, Janisse J, Coplin WM, Parker D, Jr., Norris G, Rhoney DH. A comparison of
nicardipine and labetalol for acute hypertension management following stroke. Neurocrit Care.
2008;9(2):167-76.
Chang CW, Torbey MT, Diringer MN, Coplin W, Mayer SA, Hemphill EC, et al. Neurointensivists:
part of the problem or part of the solution? Crit Care Med. 2008;36(10):2963-4; author reply 5.
Benson RR, Meda SA, Vasudevan S, Kou Z, Govindarajan KA, Hanks RA, et al. Global white
matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury. J
Neurotrauma. 2007;24(3):446-59.
Murugappan A, Coplin WM, Al-Sadat AN, McAllen KJ, Schwamm LH, Wechsler LR, et al.
Thrombolytic therapy of acute ischemic stroke during pregnancy. Neurology. 2006;66(5):768-70.
Mayer SA, Coplin WM, Chang C, Suarez J, Gress D, Diringer MN, et al. Core curriculum and
competencies for advanced training in neurological intensive care: United Council for Neurologic
Subspecialties guidelines. Neurocrit Care. 2006;5(2):159-65.
Mayer SA, Coplin WM, Chang C, Suarez J, Gress D, Diringer MN, et al. Program requirements for
fellowship training in neurological intensive care: United Council for Neurologic Subspecialties
guidelines. Neurocrit Care. 2006;5(2):166-71.
Esper DH, Coplin WM, Carhuapoma JR. Energy expenditure in patients with nontraumatic
intracranial hemorrhage. JPEN J Parenter Enteral Nutr. 2006;30(2):71-5.
Borsody M, Burke A, Coplin W, Miller-Lotan R, Levy A. Haptoglobin and the development of
cerebral artery vasospasm after subarachnoid hemorrhage. Neurology. 2006;66(5):634-40.
Albers GW, Thijs VN, Wechsler L, Kemp S, Schlaug G, Skalabrin E, et al. Magnetic resonance
imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging
evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol. 2006;60(5):508-17.

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Barrett RJ, Hussain R, Coplin WM, Berry S, Keyl PM, Hanley DF, et al. Frameless stereotactic
aspiration and thrombolysis of spontaneous intracerebral hemorrhage. Neurocrit Care.
2005;3(3):237-45.
Larive LL, Rhoney DH, Parker D, Jr., Coplin WM, Carhuapoma JR. Introducing hypertonic saline
for cerebral edema: an academic center experience. Neurocrit Care. 2004;1(4):435-40.
Rhoney DH, Tam VH, Parker D, Jr., McKinnon PS, Coplin WM. Disposition of cefepime in the
central nervous system of patients with external ventricular drains. Pharmacotherapy.
2003;23(3):310-4.
Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Free fatty acids in
cerebrospinal fluids from patients with traumatic brain injury. Neurosci Lett. 2003;349(2):136-8.
Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Measurement of
free fatty acids in cerebrospinal fluid from patients with hemorrhagic and ischemic stroke. Brain Res.
2003;985(2):198-201.
Carhuapoma JR, Gupta K, Coplin WM, Muddassir SM, Meratee MM. Treatment of refractory fever
in the neurosciences critical care unit using a novel, water-circulating cooling device. A single-center
pilot experience. J Neurosurg Anesthesiol. 2003;15(4):313-8.
Rhoney DH, Parker D, Jr., Formea CM, Yap C, Coplin WM. Tolerability of bolus versus
continuous gastric feeding in brain-injured patients. Neurological Res. 2002;24(6):613-20.
Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Free fatty acids in
human cerebrospinal fluid following subarachnoid hemorrhage and their potential role in
vasospasm: a preliminary observation. J Neurosurg. 2002;97(2):272-9.
Narayan RK, Michel ME, Ansell B, Baethmann A, Biegon A, Bracken MB, et al. Clinical trials in
head injury. J Neurotrauma. 2002;19(5):503-57.
Kraus JJ, Metzler MD, Coplin WM. Critical care issues in stroke and subarachnoid hemorrhage.
Neurol Res. 2002;24 Suppl 1:S47-57.
Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET, et al. Clinical practice
guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med.
2002;30(1):119-41.
Coplin WM, Rhoney DH, Rebuck JA, Clements EA, Cochran MS, O'Neil BJ. Randomized
evaluation of adverse events and length-of-stay with routine emergency department use of
phenytoin or fosphenytoin. Neurol Res. 2002;24(8):842-8.
Tirschwell DL, Coplin WM, Becker KJ, Vogelzang P, Eskridge J, Haynor D, et al. Intra-arterial
urokinase for acute ischemic stroke: factors associated with complications. Neurology.
2001;57(6):1100-3.
Pilitsis JG, Diaz FG, Wellwood JM, O’Regan MH, Fairfax MR, Phillis JW, et al. Quantification of
free fatty acids in human cerebrospinal fluid. Neurochem Res. 2001;26(12):1265-70.

___________________________________________________________________________________________________
15
Joshi N, Chaturvedi S, Coplin WM. Poor prognosis of acute stroke patients denied thrombolysis
due to early CT findings. J Neuroimaging. 2001;11(1):40-3.
Coplin WM, Cullen NK, Policherla PN, Vinas FC, Wilseck JM, Zafonte RD, et al. Safety and
feasibility of craniectomy with duraplasty as the initial surgical intervention for severe traumatic
brain injury. J Trauma. 2001;50(6):1050-9.
Coplin WM, Cochran MS, Levine SR, Crawford SW. Stroke after bone marrow transplantation:
frequency, aetiology and outcome. Brain. 2001;124(Pt 5):1043-51.
Coplin WM, Broderick J, Tomsick TT. Intraarterial recombinant tissue plasminogen activator for
ischemic stroke: an accelerated dosing regimen. Neurosurgery. 2001;49(1):228-9.
Coplin WM. Intracranial pressure and surgical decompression for traumatic brain injury: biological
rationale and protocol for a randomized clinical trial. Neurol Res. 2001;23(2-3):277-90.
Vinas FC, Kazmierczak C, Coplin WM. Active intracerebral hemorrhage from the lateral posterior
choroidal artery. Arch Neurol. 2000;57(6):889-90.
Tipps LB, Coplin WM, Murry KR, Rhoney DH. Safety and feasibility of continuous infusion of
remifentanil in the neurosurgical intensive care unit. Neurosurgery. 2000;46(3):596-601; discussion -
2.
Rhoney DH, Tipps LB, Murry KR, Basham MC, Michael DB, Coplin WM. Anticonvulsant
prophylaxis and timing of seizures after aneurysmal subarachnoid hemorrhage. Neurology.
2000;55(2):258-65.
Rebuck JA, Murry KR, Rhoney DH, Michael DB, Coplin WM. Infection related to intracranial
pressure monitors in adults: analysis of risk factors and antibiotic prophylaxis. J Neurol Neurosurg
Psychiatry. 2000;69(3):381-4.
Devlin JW, Coplin WM, Murry KR, Rengachary SS, Wilson RF. Nimodipine-induced acute
hypoxemia: case report. Neurosurgery. 2000;47(5):1243-6; discussion 6-7.
Coplin WM, Pierson DJ, Cooley KD, Newell DW, Rubenfeld GD. Implications of extubation delay
in brain-injured patients meeting standard weaning criteria. Am J Respir Crit Care Med.
2000;161(5):1530-6.
PRESENTATIONS
International/national, local/regional, and invited Seminars and Grand Rounds since May
2013
1. Online Live Chat – Stroke Prevention – Centura Health – 5/23/13
2. Stroke in the Emergency Department: What to do… - St. Catherine Hospital (med staff) –
5/29-13
3. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – University of
Virginia Neurology Grand Rounds – 5/31/13
4. Optimal Glucose Control in Hemorrhagic Stroke – St. Anthony Hospital (MD/RN) –
6/13/13
5. TBI Case Studies – St. Anthony Neuro/Trauma Nursing Staff – monthly x 2, first 6/14/13

___________________________________________________________________________________________________
16
6. Brain Injury Management – Grand Rounds Santo Tomas Hospital, Panama – 6/19/13
7. Delayed Brain Injury - 3rd
International Neurocritical Care Symposium, Panama – 6/20/13
8. Updates in Neuromonitoring of TBI Patients - 3rd
International Neurocritical Care
Symposium, Panama – 6/20/13
9. Brain Tissue Oxygen Based Therapy and Outcome after Severe Traumatic Brain Injury - 3rd
International Neurocritical Care Symposium, Panama – 6/21/13
10. Update in the Management of Traumatic Spinal Cord Injury - 3rd
International Neurocritical
Care Symposium, Panama – 6/21/13
11. Traumatic Spinal Cord Injury – St. Anthony Trauma Multidisciplinary QI – 7/1/13
12. Early Goal Directed Therapy for Traumatic Brain Injury – Cheyenne Regional Medical
Center (WY) – 7/9/13
13. Hospital Neurological Assessments – Penrose Hospital (Centura Stroke Coordinators’
monthly meeting) – 7/12/13
14. Traumatic Spinal Cord Injury – Panorama Orthopedics (physician/PA staff) – 7/15/13
15. Controversies in Spine Injury – Parker Adventist Hospital (Spine Committee) – 7/30/13
16. Clearing the Spine in the ED: Exam, Imaging, Gear Removal, and Transition to Further
Care: The Neuro Doc's Perspective – 1st
Annual Rocky Mountain Sports Medicine
Symposium, Durango – 8/2/13
17. Hypoxia Unplugged: Altitude and Carbon Monoxide– 1st
Annual Rocky Mountain Sports
Medicine Symposium, Durango – 8/3/13
18. Neurological Assessment – St. Anthony North (nursing) – 8/7/13
19. You Won’t Get Far If You Keep On Sticking Your Hand In The Medicine Jar: Steroids
Work, Don’t They? – Littleton Adventist Hospital (trauma) – 8/15/13
20. Transfusion “Requirements” in Traumatic Brain Injury – Littleton Adventist Hospital
(trauma) – 8/15/13
21. Toxic Encephalopathies: Ethanol Withdrawal – Critical Care Karma, Porter Adventist
Hospital – 8/21/13
22. Blood Pressure Management for Different Types of Stroke - St. Anthony Hospital –
8/26/13
23. Severe Traumatic Brain Injury: Initial Assessment and Resuscitation – St. Anthony Hospital
– 8/29/13
24. Use of Clinical Examination Scales in Patients with Neurological Injury: Why All the
Confusion? – St. Anthony Hospital (Neurocritical Care board review series) – 9/9/13
25. Monitoreo Multimodal en Neurointensivo - Asociación Colombiana de Medicina Interna –
Pasto – 9/13/13
26. Presión Tisular de Oxígeno Cerebral - Asociación Colombiana de Medicina Interna – Pasto
– 9/13/13
27. Minimizing Perioperative Spine Surgery Infections: Why All The Confusion? – Parker
Adventist Hospital (Spine Committee) – 9/17/13
28. Traumatic Spinal Cord Injury – Neurocritical Care Society – Philadelphia – 10/2/13
29. General Approach to Ventilating the Comatose Trauma Patient – St. Anthony Hospital
(trauma) – 10/7/13
30. Fluids, Electrolytes, Resuscitation Do’s and Don’ts – St. Anthony Hospital (Neurocritical
Care board review series) – 10/10/13
31. Hypercalcemia – Heart of the Rockies Regional Medical Center, Salida – 10/10/13
32. Coagulopathies – Littleton Adventist Hospital (trauma) – 10/17/13
33. Acute Management of Neurological Emergencies – St. Mary-Corwin (nursing) – 10/19/13
34. Neuropharmacology – Rocky Mountain Neurocritical Care Conference – 10/29/13
35. Neuroendocrinology – Rocky Mountain Neurocritical Care Conference – 10/30/13
36. Spinal Cord Injury – Rocky Mountain Neurocritical Care Conference – 10/30/13
37. Natural, Supernatural, and Man-Made Catastrophes – Rocky Mountain Neurocritical Care

___________________________________________________________________________________________________
17
Conference – 10/30/13
38. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – St. Mary’s Medical
Center’s 4th Annual Neuroscience Symposium – Advancements in Neuroscience, Palm
Beach Gardens, FL – 11/2/13
39. Traumatic Intracranial Hemorrhage – Mercy Regional Medical Center Trauma Conference –
11/9/13
40. Traumatic Intracranial Hemorrhage – Mercy Regional Medical Center – 11/11/13
41. Toxic Encephalopathies: Ethanol Withdrawal – Mercy Regional Medical Center – 11/11/13
42. Mild TBI Transfer Algorithm – Mercy Regional Medical Center – 11/13/13
43. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – Critical Care Karma
- 11/18/13
44. Severe TBI – St. Anthony Hospital (Neurocritical Care board review series) – 11/26/13
45. Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The
Confusion? – St. Vincent Hospital, Leadville – 12/2/13
46. Multimodality Monitoring in Neurocritical Care – St. Anthony Hospital (Neurocritical Care
board review series) – 12/5/13
47. Spinal Cord Injury – St. Anthony Hospital (nursing) – 12/6/13
48. There Will Be Blood – Aspen Valley Hospital (trauma) – 12/10/13
49. Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The
Confusion? – Mercy Regional Medical Center – 12/11/13
50. “Neuroradiology”. Lecture for RNs. St. Anthony Hospital - 2/20/14
51. “HACA: 33 vs 36C”. CCPSA Journal Club. St. Anthony Hospital - 2/24/14
52. “Traumatic Brain Injury”. Wilz Neuroscience and Trauma Symposium. Pueblo Convention
Center - 3/1/14
53. “Appropriate TBI Admissions and TBI Management, Including Rehab and Follow Up”. San
Luis Valley Regional Medical Center - 3/17/14
54. “Fluid and Electrolyte Management In Critically-Ill Patients After Neurological
Catastrophes”. Neurotrauma Critical Care Review and Update for Practicing Neurosurgeon.
82nd
American Association of Neurological Surgeons Annual Scientific Meeting, San
Francisco - 4/5/14
55. “Traumatic Brain Injury”. Miners’ Colfax Medical Center. Raton, NM - 4/10/14
56. “Telestroke” St. Thomas More Emergency Department. Canon City, CO - 4/16/14
57. “Alcohol Withdrawal Syndrome: A New Approach To Prevention and Intervention of
Severe Alcohol Withdrawal Symptoms”. Mercy Regional Medical Center. Durango, CO -
4/17/14
58. “Alcohol Withdrawal Syndrome: Interdepartmental/Interdisciplinary Approach Based on
the Evidence Based Medicine Review”. Mercy Regional Medical Center. Durango, CO -
4/17/14
59. “Alcohol Withdrawal Syndrome: Protocol/Standardization of Treatment in Inpatients, Pre-
ICU, ICU, and ED Patients”. Mercy Regional Medical Center. Durango, CO - 4/17/14
60. “Traumatic Brain Injury”. Platte Valley Medical Center - 4/24/14
61. “Therapeutic Temperature Management after Neurological Catastrophe: Why All the
Confusion?”. Trauma Multidisciplinary Meeting. St. Anthony Hospital - 5/5/14
62. “Hospital Neurological Stroke Assessments”. Mega Nursing Grand Rounds. Porter
Adventist Hospital - 5/6/14
63. “Disability”. Rural Trauma Team Development Course. San Luis Valley Regional Medical
Center - 5/8/14
64. “Zombie Neurobiology: Are We Ready For The Looming Apocalypse?” South State EMS.
Penrose Hospital. Colorado Springs, CO - 5/13/14
65. “Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The
Confusion?” Pagosa Springs Medical Center - 5/15/14

___________________________________________________________________________________________________
18
66. “Mild Brain Injury – When to Refer; When and Where to Manage”. Brain Injury Alliance of
Colorado Summit County Conference. Beaver Run, CO - 5/16/14
67. “VTE Prophylaxis Timing after Brain and/or Spinal Cord Injury”. Penrose-St. Francis
Trauma Education. Colorado Springs, CO – 9/5/14
68. “Traumatic Spinal Cord Injury”. Neurocritical Care Society. Seattle, WA – 9/10/14
69. “Guidelines are great for neurocritical care in general, but not for real experts like me.”
Neurocritical Care Society. Seattle, WA – 9/14/14
70. “Concussion”. Copper Mountain Emergency Medicine. Edwards, CO – 10/23/14
71. “Head Injury and Hollywood: A Case Study of the Three Stooges”. Mercy Regional Medical
Center Trauma Conference. Durango, CO – 10/25/14
72. “Urgent Warfarin Reversal”. Association of California Nurses. Santa Ana, CA – 10/28/14
73. “Association Between Pharmacological Thromboprophylaxis and Hemorrhage Progression
in Patients with Hemorrhagic Stroke”. St. Mary’s Medical Center’s 5th Annual Neuroscience
Symposium – A Lustrum of Progress. Palm Beach Gardens, FL – 11/1/14
74. “Association Between Pharmacologic Thromboprophylaxis and Hemorrhage Progression in
Patients With Hemorrhagic Stroke”. Best of AHA Specialty Conferences at Scientific
Sessions. Chicago, IL – 11/17/14
75. “Concussion and Clearing the Spine in the ED: Exam, Imaging, Gear Removal, and
Transition to Further Care”. Rio Grande Hospital Quarterly Trauma Review and CME. Del
Norte, CO – 11/21/14
76. “Current Trends In Neurotrauma”. Wilz Trauma Symposium. Pueblo, CO – 3/7/15
77. “Zombie Neurobiology: Are We Ready For The Looming Apocalypse?”. 12th
Annual Critical
Care Symposium. Manchester, UK – 4/23/15
78. “Pharmacological Thromboprophylaxis, Venous Thromboembolism & Hemorrhage
Progression In Patients With Hemorrhagic Stroke: Why All The Confusion? 12th
Annual
Critical Care Symposium. Manchester, UK – 4/24/15
79. “Neurocritical Care Update” 12th
Annual Critical Care Symposium. Manchester, UK –
4/24/15
80. “Extubation Readiness Independent Of Level Of Consciousness”. 12th
Annual Critical Care
Symposium. Manchester, UK – 4/24/15
81. “Coagulopathy and VTE: Timing of Use of Chemical Prophylaxis & Management of VTE
Events in the Perioperative Period”. Neurotrauma Critical Care Review and Update. 83rd
American Association of Neurological Surgeons Annual Scientific Meeting. Washington, DC
– 5/2/15

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