Calyx Bio-Ventures Inc. trades on the TSX Venture Exchange under the symbol "CYX" and owns a majority position in Agrisoma Biosciences Inc. Agrisoma is an agricultural biotechnology company that uses a proprietary Engineered Trait Loci (ETL) technology licensed from Calyx to commercialize a suite of industry-leading oil quality and crop improvement traits for use in energy feedstock crops. For further information about Calyx, its technology, collaborations and partnerships, please visit www.calyxbio.com.
Resonance™ is a trademark of Agrisoma Biosciences Inc.
For more information about Resonance, visit www.agrisoma.com.
2. ………………………………………………………………………………………………………
Forward
Looking
Statements
Certain
statements
contained
in
this
document
constitute
“forward
looking
statements”.
When
used
in
this
document,
the
words
“may”,
“would”,
“could”,
“will”,
“intend”,
“plan”,
“propose”,
“anticipate”,
“believe”,
“forecast”,
“estimate”,
“expect”
and
similar
expressions
as
they
relate
to
the
Company
or
its
management,
are
intended
to
identify
forward-‐looking
statements.
Such
statements
reflect
the
Company’s
current
views
with
respect
to
future
events
and
are
subject
to
certain
risks,
uncertainties
and
assumptions.
Many
factors
could
cause
the
Company’s
actual
results,
performance
or
achievements
to
be
materially
different
from
any
future
results,
performance
or
achievements
that
may
be
expressed
or
implied
by
such
forward-‐looking
statements.
Given
these
risks
and
uncertainties,
readers
are
cautioned
not
to
place
undue
reliance
on
such
forward-‐looking
statements.
The
Company
does
not
intend,
and
does
not
assume
any
obligation,
to
update
any
such
factors
or
to
publicly
announce
the
result
of
any
revisions
to
any
of
the
forward
looking
statements
contained
herein
to
reflect
future
results,
events
or
developments
except
as
required
by
law.
2www.calyxbio.com
3. ………………………………………………………………………………………………………
We’re
all
about
• leveraging
our
IP
to
improve
crop
yield
&
performance
• the
first
crop
“Resonance-‐carinanta”
can
…
• reduce
the
world’s
petroleum
dependence
and
greenhouse
gas
emissions
associated
with
transportation
fuels
by
creating
a
…
• drop-‐in,
cost
competitive
alternative
to
petroleum-‐derived
fuels,
compatible
with
existing
engines
yet
with
superior
performance.
3www.calyxbio.com
a
scalable
seed
business
5. ………………………………………………………………………………………………………
• Calyx
owns
a
proprietary
portfolio
of
patents
with
respect
to
modifying
and
engineering
agricultural
crop
traits
• Technologies
have
been
licensed
to
Agrisoma
Biosciences
Inc.,
a
majority-‐
owned
subsidiary,
which
is
applying
these
technologies
primarily
to
a
new
oilseed
crop
called
Resonance®”,
a
variety
of
brassica
carinata
• Resonance
carinata
produces
oil
that
is
superior
for
industrial
applications,
such
as
biofuel
production,
than
are
food-‐based
oils
like
soy
or
canola
• Resonance
carinata
grows
more
oil
per
acre
than
other
oilseed
feedstocks
on
target
lands
• Agrisoma
is
a
seed
technology
company
that
sells
Resonance
carinata
seed
to
farmers.
2012
was
the
commercial
launch
of
Resonance
carinata
seed
sales
5www.calyxbio.com
Renewable
Energy
Rooted
in
Technology
6. ………………………………………………………………………………………………………
Carinata
Uses
100%
of
the
Resonance
carinanta
crop
is
used
and
produces
two
products:
oil
&
meal
OIL
-‐
CAN
BE
REFINED
INTO
• drop-‐in
jet
fuel
• biodiesel
• other:
naptha,
emulsifiers
MEAL
•
animal
feed
that
is
high
in
soluble
protein
•
approved
for
sale
in
the
United
States
as
cattle
feed
6
www.calyxbio.com
7. ………………………………………………………………………………………………………
7www.calyxbio.com
Why
Resonance?
• multi-‐billion
gallon
demand
for
renewable
oil
feedstock
for
biodiesel
and
biojet
fuel
from
non-‐food
sources
• aviation
is
an
industry
that
has
committed
itself
to
zero
carbon
growth
through
biojet
fuel
usage,
creating
huge
demand
• Resonance
carinata
offers
a
hugely
scalable
opportunity
to
profitably
produce
high-‐quality
renewable
oil
at
a
price
point
superior
to
other
feedstocks
• Resonance
carinata
is
suited
to
semi-‐arid
lands
and
crop
rotations
and
can
be
scaled
to
multi-‐millions
of
acres
of
production
without
displacing
food
crops
• Resonance
carinata
utilizes
existing
infrastructure
throughout
the
farm
to
the
end-‐user
9. ………………………………………………………………………………………………………
Resonance
carinata
=
oil
+
meal
• sustainable
production
on
semi-‐arid,
marginal
lands
• 40M+
acres
of
lands
suitable
for
Resonance
in
just
North
America
• ideal
rotation
crop
-‐
no
displacement
or
competition
with
food
crops
• Resonance
carinata
entered
first
commercial
year
in
2012
–
successfully
harvested
6,000+
acres
at
all
growing
sites
• meal
approved
for
sale
as
cattle
feed
in
the
USA
99
www.calyxbio.com
10. ………………………………………………………………………………………………………
growers
have
fallow
lands
Crop
Ramp-‐Up
ü 2011
-‐
50
acres
ü 2012
-‐
6,049
acres
Ø significant
grower
demand
for
product
Ø excellent
performance
in
drought
conditions
Ø scalable
business
opportunity
into
key
US
markets
Ø in
excess
of
40
million
acres
of
production
capacity
in
North
America
alone
10
Market
development
through
field
tours
and
trade
show
promotion
with
target
growers
www.calyxbio.com
11. ………………………………………………………………………………………………………
grower
marketing
&
support:
Crop
Walk
Series
(summer
2012)
1111
• farmer
focused,
field
walks
of
production
sites
• opportunity
to
meet
with
producers
and
see
real
world
results
• total
2012
summer
Crop
Walk
Series
reached
500
growers
across
AB
&
SK
13. ………………………………………………………………………………………………………
Global Demand for Energy
Crop Feedstock
2006
% of total
production
2012
% of total
production
Oilseeds 6% 25%
Palm oil 3% 21%
Wheat / barley 1% 2%
Corn 7% 15%
Sugarcane 17% 28%
Source : Rabobank analysis
2006 2012
Ethanol 11 B gal 27 B gal
Biodiesel 2 B gal 8.9 B gal
Total 13 B gal 35.9 B gal
Biofuel Demand Biofuel Feedstock Source
Ø according
to
the
International
Energy
Agency,
or
IEA,
biofuel
production
could
reach
approximately
112B
gallons
by
2030.
To
meet
these
targets,
the
IEA
believes
feedstock
production
would
need
to
increase
to
150M
acres
in
2030,
up
from
75M
acres
in
2010.
Ø oilseeds
are
the
fastest
growing
feedstock
source
–
biodiesel
and
aviation
13
Source : Cere’s S-1
www.calyxbio.com
14. ………………………………………………………………………………………………………
Dedicated Feedstock Crops Enable The
Biofuels Value Chain
• Feedstock Oil
Quality & Cost
• Production on
Farm –
Scalability,
Infrastructure
• Crop Processing
and Delivery of
Oil
• Biofuel –
Manufacturing
Efficiencies
long
chain
oils
–
uniform
chemistry
for
manufacturing
efficiencies
-‐
lower
cost
than
food
oils
being
used
now
easily
scaled
to
large
acreage
-‐
Crop
production
infrastructure
in
place,
including
strong
agronomic
package
–
growers
engaged
and
committed
to
Carinata
production
standard
oilseed
processing
with
valuable
meal
co-‐product,
uses
current
infrastructure
long
chain
oils
=
most
efficient
feedstock
for
conversion
technologies
–
less
waste,
more
fuel,
better
quality
fuel
Value
Chain
-‐
Needs
Resonance
Carinata
Energy
Feedstock
Solution
14
15. ………………………………………………………………………………………………………
competitive
edge
for
Resonance
carinata
• high
concentration
of
Erucic
acid
(22:1)
• two
jet
fuel
molecules
(C8-‐C14)
from
one
C22
fatty
acid
whereas
C18
oils
can
only
produce
one
jet
fuel
molecule
• higher
yields
of
jet
fuel
and
better
cost
structure
• higher
probability
of
optimal
cracking
and
diversity
of
carbon
chains
15
17. ………………………………………………………………………………………………………
April
2012:
Porter
Airlines
Flight
17
• on
April
17,
2012
Porter
Airlines
conducted
Canada's
first
bio-‐fuel
powered
revenue
flight
• porter
airlines
flew
one
of
its
Bombardier
Q400
turboprops
from
its
base
at
Billy
Bishop
Toronto
City
Airport
to
Ottawa
using
a
50/50
blend
of
biofuel
and
Jet
A1
fuel
in
one
of
its
engines.
The
fuel
was
certified
to
the
new
American
Society
for
Testing
and
Materials
(ASTM)
D7566/D1655
standard
and
the
biofuel
used
was
derived
from
oilseed
crops
including
the
Resonance
oilseed
grown
and
produced
by
Agrisoma.
www.calyxbio.com
18. ………………………………………………………………………………………………………
April
2012:
NRC
National
Research
Council
18www.calyxbio.com
• biojet
fuel
refined
from
Resonance-‐Carinata
blended
50/50
with
petroleum-‐based
jet
fuel
for
NRC
flight
• real-‐time,
in-‐flight
emissions
testing
conducted
by
trailing
jet
using
a
“sniffer
probe”
“particulate emissions, including aerosols of black carbon, sulphates
and by-products of the combustion of aromatic compounds, are
significantly lower”
In-flight trailing emissions testing in six independent flight segments using
Honeywell Green Jet Fuel™ including above the 50/50 blend ratio1
1As reported by the National Research Council Aerospace at the Farnborough Airshow July 9, 2012
19. ………………………………………………………………………………………………………
October
2012:
a
world
first
!
civilian
jet
aircraft
powered
by
100%
biofuel
19www.calyxbio.com
NRC
flew
a
Falcon
20
jet
powered
100%
by
biojet
fuel
refined
from
Resonance-‐carinata.
This
flight
was
the
first
time
in
the
world
a
civilian
jet
aircraft
was
powered
by
100%,
un-‐
blended,
renewable
jet
fuel
that
met
petroleum
jet
fuel
specifications
Results
of
Flight:
• no
engine
modifications
were
required
• 50%
reduction
in
aerosol
emissions
• 25%
reduction
in
particles
• 49%
reduction
in
black
carbon
• improvement
of
1.5%
in
fuel
consumption
21. ………………………………………………………………………………………………………
Next
Steps:
North
American
Expansion,
Extensive
Testing
Program
21
• northern
production
zone
• 50
trials,
27
locations
• nursery
sites
established:
• Swift
Current,
Saskatchewan
• Minot,
North
Dakota,
SDSU
• winter
crop
development
in
the
south:
• Successful
testing
in
Mississippi
valley
and
Southeast
(Univ
Florida)
• North
America
production
potential
exceeds
40MM
acres
without
impacting
food
production
22. ………………………………………………………………………………………………………
Continued
Development:
ETL
technology
• our
ETL
technology
is
a
proprietary,
field-‐
validated
crop
improvement
platform
that
creates
enhanced
crops
• the
platform
is
able
to
efficiently
introduce
or
stack
multiple
traits
simultaneously
into
engineered
plant
chromosomes
• the
ability
to
introduce
all
of
these
traits
in
one
cycle
is
far
superior
to
current
trait
introduction
methods
that
require
multiple
cycles
• ETL
will
significantly
increase
the
amount
of
oil
per
acre
yielded
and
further
enhance
the
superior
economics
of
Resonance-‐carinata
• ETL
technology
viability
supported
by
licensing
agreement
with
Dow
Agrosciences,
which
has
licensed
ETL
for
use
in
food
crops
22www.calyxbio.com
23. ………………………………………………………………………………………………………
Continuous
Improvement:
breeding
&
trait
stacking
23
• Breeding:
• largest
Brassica
Carinata
collection
in
the
world,
over
1,000
accessions
• hybrid
development,
extensive
testing
program
with
over
>50
trials,
winter
and
summer
nurseries
• molecular
markers,
haploidy,
hybrids,
genome
sequencing,
advanced
breeding
tools
• Traits:
• unique
trait
stacking
ability:
proven
chromosome
engineering
technology
(Engineered
Trait
Loci
-‐
ETL)
• extensive
trait
collection
related
to
oil
and
yield
23
24. ………………………………………………………………………………………………………
Business
Milestones
ü Initial
commercial
rollout
–
6,000
acres
seeded
and
harvested
in
2012
ü secured
strategic
partnership
with
PGF
Biofuels
for
logistics,
handling
&
commercial
contracting
in
North
America
&
Australia
ü commercial
test
flights
ü acquired
majority
ownership
of
Agrisoma
Biosciences
Inc.
ü Introduced
higher
yielding
line
of
Resonance
carinata
in
2013
q secure
off-‐take
agreements
q biojet
fuel
production
underway
q Certification
of
carinata
under
Renewable
Fuel
Standard
in
USA
q meal
approval
in
Canada
q continue
trials
in
USA
in
advance
of
commercialization
q continue
field
trials
of
ETL
Carinata
to
achieve
commercial
status
by
2015
24www.calyxbio.com
25. ………………………………………………………………………………………………………
Why
Calyx?
ü timing:
16
years
of
science
and
$20
million
of
aggregate
investment
-‐
commercial
product
now
ready
ü management
track
record
of
building
companies
and
delivering
returns
to
shareholders
ü proprietary
technologies:
Calyx
owns
master
license
for
“ETL”
chromosome
technology
and
Agrisoma
owns
the
breeder
rights
for
Carinata
ü 2012
saw
first
significant
seed
sales
and
crop/revenue
growth
–
6,000+
acres
planted
ü great
crop
performance
on-‐farm
in
spite
of
2012’s
severe
drought
conditions
in
much
of
North
America
ü huge
market
for
oilseed
feedstock
–
currently
a
feedstock
shortage
exists
globally
including
North
America
–
strong
demand
means
farmers
will
quickly
adopt
Carinata
ü Carinata
provides
feedstock
better
suited
to
fuel
and
industrial
uses
than
other
feedstocks,
thereby
enabling
biofuel
production
to
be
more
economic
–
sustainable
competitive
advantage
25www.calyxbio.com
26. ………………………………………………………………………………………………………
Calyx
Bio-‐Ventures
capital
structure
26
Calyx
Bio-‐Ventures
Inc.
(CYX-‐T)
capital
structure
common
shares
issued
&
outstanding:
29.8
million
fully
diluted:
39.3
million
recent
price:
$0.27
market
capitalization:
~$8
million
v Closed
on
$4.0M
in
December
2012
@
$0.30/unit
with
a
½
warrant
(1-‐year)
at
$0.60
www.calyxbio.com
Calyx’s
ownership:
50.0%
BDC
Venture
Capital’s
ownership:
49.9%
Others:
0.1%
v Each
party
responsible
for
pro-‐rata
portion
of
Agrisoma
funding
Agrisoma
Biosciences
Inc.,
capital
structure
27. ………………………………………………………………………………………………………
Calyx Bio-Ventures Management
27
Wm. Hugh Notman, President & CEO
• Partner at Stirling Mercantile Corporation, corporate
finance advisory
• Corporate director of public and private companies
Richard Whittall, Director
• CEO Newstrike Capital Inc. ($300M Market Cap)
• Corporate director of several public and private
companies
• Former Director of Burcon Nutrascience
Kevin Rathbun CFA, Corporate Development
• Former CFO of Realm Energy (bought out in 2011)
• Director of Newstrike Capital Inc.
Keir Reynolds, Investor Relations
• President of Mammoth Market Advisory Corp.
• Raised in excess of $120M in public venture capital
Stuart MacGregor, Director
• President of MacGregor Equities Inc., a Toronto
based manager of an investment partnership
with a focus on private equity investments;
previously, a Partner of Polar Capital
Corporation
David T Howard, Director
• Previously a director of JRI International Ltd., a
privately-owned agriculture company and
SemBioSys Genetics, Inc., an ag-biotech
company
Louis P Lacasse, Director
• President of GeneChem Management Inc.,
manager of a specialized biotechnology venture
fund
www.calyxbio.com
28. ………………………………………………………………………………………………………
Agrisoma - Management Team
• Steven Fabijanski, PhD President & CEO
• 20+ years senior executive experience in the agriculture and biotechnology industry,
previously built and sold a seed company specializing in oilseed technology (Sold to
Pioneer)
• Patrick Crampton, MBA VP Business Development
• 15+ years global marketing and product management for Syngenta Seeds
• Michael Lindenbaum, PhD VP Technology
• 15+ years R & D, inventor, as well as the scientific and technical leader of the ETL
technology applications
28
Supported by management and advisors with decades of agricultural business experience:
• Daryl Males – Agrisoma Product Manager (previously product development manager at Viterra Inc.)
• Mejda Lortie – Director of Government & Regulatory Affairs (previously government affairs leader at Biotech Canada)
www.calyxbio.com