2. Defects Generation During Coating Activity
Defects Nature Reason Picture
Picking And
Sticking
Coating removes a
piece of the tablet
from the core.
Over wetting
Under drying
Poor Tablets Quality
Bridging Coating fills in the
letters or logo on the
tablet.
Poor Design of the Tablets
Embossing
High Coating Solution
Viscosity
High percentage of solids in
the solution
Improper atomization
pressure
Excess application of the
solution.
3. Defects Nature Reason Picture
Twinning - Two tablets stick together
- Common issue in Capsule
shape tablets
Low Pan RPM with
high spray rate
Tooling Design
Peeling - Slight coating sheet
removed from the coated
tablets
Coating solution not
sticking properly
Over wetting
High moisture
content in the core
tablets.
Defects Generation During Coating Activity
4. Defects Generation During Coating Activity
Defects Nature Reason Picture
Erosion Soft Tablet
Generation
An Over Wetted Tablet
Surface
Inadequate Drying
Lack Of Tablet Surface
Strength
Mottled
Colour
Colour spots on
tablets
Actual spray rate differs
from target rate.
The tablets are cold
Improper preparation of
solution
Shade
Variation
Uneven Spray rate Gun Choking
Solid Particles not dissolved
in water or solvent
Improper preparation of
solution