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Defects Generation During Coating Activity
Defects Nature Reason Picture
Picking And
Sticking
Coating removes a
piece of the tablet
from the core.
 Over wetting
 Under drying
 Poor Tablets Quality
Bridging Coating fills in the
letters or logo on the
tablet.
 Poor Design of the Tablets
Embossing
 High Coating Solution
Viscosity
 High percentage of solids in
the solution
 Improper atomization
pressure
 Excess application of the
solution.
Defects Nature Reason Picture
Twinning - Two tablets stick together
- Common issue in Capsule
shape tablets
 Low Pan RPM with
high spray rate
 Tooling Design
Peeling - Slight coating sheet
removed from the coated
tablets
 Coating solution not
sticking properly
 Over wetting
 High moisture
content in the core
tablets.
Defects Generation During Coating Activity
Defects Generation During Coating Activity
Defects Nature Reason Picture
Erosion Soft Tablet
Generation
 An Over Wetted Tablet
Surface
 Inadequate Drying
 Lack Of Tablet Surface
Strength
Mottled
Colour
Colour spots on
tablets
 Actual spray rate differs
from target rate.
 The tablets are cold
 Improper preparation of
solution
Shade
Variation
Uneven Spray rate  Gun Choking
 Solid Particles not dissolved
in water or solvent
 Improper preparation of
solution
Problems during coating and trouble shooting

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Problems during coating and trouble shooting

  • 2. Defects Generation During Coating Activity Defects Nature Reason Picture Picking And Sticking Coating removes a piece of the tablet from the core.  Over wetting  Under drying  Poor Tablets Quality Bridging Coating fills in the letters or logo on the tablet.  Poor Design of the Tablets Embossing  High Coating Solution Viscosity  High percentage of solids in the solution  Improper atomization pressure  Excess application of the solution.
  • 3. Defects Nature Reason Picture Twinning - Two tablets stick together - Common issue in Capsule shape tablets  Low Pan RPM with high spray rate  Tooling Design Peeling - Slight coating sheet removed from the coated tablets  Coating solution not sticking properly  Over wetting  High moisture content in the core tablets. Defects Generation During Coating Activity
  • 4. Defects Generation During Coating Activity Defects Nature Reason Picture Erosion Soft Tablet Generation  An Over Wetted Tablet Surface  Inadequate Drying  Lack Of Tablet Surface Strength Mottled Colour Colour spots on tablets  Actual spray rate differs from target rate.  The tablets are cold  Improper preparation of solution Shade Variation Uneven Spray rate  Gun Choking  Solid Particles not dissolved in water or solvent  Improper preparation of solution