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1. Schröppel B, Fischereder M, Wiese P, Segerer S, Huber S,
Kretzler M, Heiss P, Sitter T, Schlöndorff D: Expression of glucose
transporters in human peritoneal mesothelial cells. Kidney Int 1998, 53:
1278-1287
4,9
2. Segerer S, Meister P: Die erworbene, zystische
Nierenerkrankung bei chronischen Dialysepatienten: eine retrospektive
Studie an 125 Autopsien (Teil 1, Zysten). Pathologe 1998, 19: 292-298
0,3
3. Segerer S, Meister P: Die erworbene, zystische
Nierenerkrankung bei chronischen Dialysepatienten: eine retrospektive
Studie an 125 Autopsien (Teil 2, Tumoren). Pathologe 1998, 19: 368-
372
0,3
4. Segerer S, Bogner J, Walli R, Loch O, Goebel FD.
Hyperlipidemia under treatment with proteinase inhibitors. Infection
1999, 27: 77-81
1,6
5. Segerer S, Mack M, Regele H, Kerjaschki D, Schlöndorff D.
Expression of the chemokine receptor CCR5 in human kidney diseases.
Kidney Int 1999, 56:52-64
4,9
6. Eitner F, Cui Y, Hudkins KL, Stokes MB, Segerer S, Mack M,
Lewis PL, Abraham AA, Schlöndorff D, Gallo G, Kimmel PL, Alpers CE.
Chemokine receptor CCR5 and CXCR4 expression in HIV-associated
kidney disease. J Am Soc Nephrol 2000, 11:856-867
7,1
7. Huber SM, Braun GS, Segerer S, Veh RW, Horster MF:
Metanephrogenic mesenchyme-to-epithelium transition induces
profound expression changes of ion channels. Am J Physiol 2000, 279:
F65
4,4
8. Segerer S, Regele H, Mack M, Kain R, Cartron JP, Colin Y,
Kerjaschki D, Schlöndorff D. The duffy antigen receptor for chemokines
is up-regulated during acute renal transplant rejection and crescentic
glomerulonephritis. Kidney Int 2000, 58: 1546-1556
4,9
9. Segerer S, Cui Y, Hudkins KL, Goodpaster T, Eitner F, Mack M,
Schlöndorff D, Alpers CE. Expression of the chemokine monocyte
chemoattractant protein-1 and its receptor chemokine receptor 2 in
human crescentic glomerulonephritis. J Am Soc Nephrol 2000, 11: 2231-
2242
7,1
10. Segerer S, Cui Y, Eitner F, Goodpaster T, Hudkins KL, Mack M,
Cartron JP, Colin Y, Schlöndorff D, Alpers CE. Expression of
chemokines and chemokine receptors during human renal transplant
rejection. Am J Kidney Dis 2001, 37: 518-531
4
11. Segerer S, Tenada S, Hudkins KL, Cui Y, Farr A, Alpers CE.
Cryoglobulinemic glomerulonephritis in Thymic Stromal Lymphopoeitin
Transgenic Mice. Am J Path. 2001, 159: 2355-2369
5,5
12. Hudkins KL, Le QC, Segerer S, Johnson RJ, Davis CL, Giachelli
CM, Alpers CE. Osteopontin expression in cyclosporin toxicity. Kidney
Int 2001, 60. 635-640
4,9
13. Anders HJ, Vielhauer V, Cohen C, Kretzler M, Segerer S, Luckow B,
Weller L, Gröne HJ, Schlöndorff D. Chemokine and chemokine receptor
expression during induction and resolution of immune complex
glomerulonephritis. J Am Soc Nephrol 2001, 12: 919-931
7,1
14. Segerer S, Eitner F, Cui Y, Hudkins KL, Alpers CE. Cellular injury
associated with renal thrombotic microangiopathy in human
immunodeficiency virus- infected macaques. J Am Soc Nephrol 2002,
13: 370-378
7,1
15. Segerer S, Hudkins KL, Taneda S, Wen M, Cui Y, Segerer M, Farr
A, Alpers CE. Oral interferon alpha treatment of mice with
cryoglobulinemic glomerulonephritis. Am J Kidney Dis 2002, 39: 876-
888
4
16. Segerer S, Hughes E, Hudkins KL, Mack M, Goodpaster T, Alpers
CE. Expression of the fractalkine receptor (CX3CR1) in human kidney
diseases. Kidney Int 2002, 62: 488-495
4,9
17. Alpers CE, Hudkins KL, Segerer S, Sage HE, Pichler R, Couser
WG, Johnson RJ, Bassuk JH. Localization of SPARC in developing,
mature, and renal allograft rejection. Kidney Int 2002, 62: 2073-2086
4,9
18. Wen M, Segerer S, Dantes M, Brown P, Hudkins KL,
Goodpasture T, Kirk L, LeBoeuf RC, Alpers CE. Renal Lesions in
Apolipoprotein E Deficient Mice. Lab Invest. 2002, 82: 999-1006
4,5
19. Braun GS, Veh RW, Segerer S, Horster MF, Huber SM.
Developmental expression and functional significance of Kir channel
subunits in ureteric bud and nephron epithelia. Pflügers Archiv 2002,
445: 321-30
3,8
20. Taneda S, Hudkins KL, Cui Y, Farr AG, Alpers CE, Segerer S.
Growth factor expression in a murine model of cryoglobulinemia. Kidney
Int 2003, 63: 576-590
4,9
21. Lee JS, Frevert CW, Thorning DR, Segerer S, Alpers CE,
Cartron JP, Colin Y, Wong VA, Martin TR, Goodman RB. Enhanced
expression of the Duffy antigen during suppurative pneumonia. J
Histochem Cytochem 2003, 51: 159-166
2,3
22. Segerer S, Böhmig GA, Exner M, Colin Y, Cartron JP,
Kerjaschki D, Schlöndorff D, Regele H. When renal allografts turn Darc.
Transplantation 2003, 75:1030-1034
3,6
23. Mühlfeld AS, Segerer S, Hudkins KL, Carling MD, Wen M, Farr
AG, Ravetch JV, Alpers CE. Deletion of the Fc receptor IIb in TSLP
transgenic mice aggravates membranoproliferative glomerulonephritis.
Am J Kidney Dis 2003, 163: 1127-1136
4
24. Spencer MW, Muhlfeld AS, Segerer S, Hudkins KL, Kirk E,
LeBoeuf RC, Alpers CE. Hyperglycemia and Hyperlipidemia Act
Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB
Mice. Am J Nephrol. 2004, 24: 20-31
2,2
25. Segerer S, Banas B, Wörnle M, Schmid H, Cohen C, Kretzler M,
Mack M, Kiss E, Nelson PJ, Schlöndorff D, Gröne HJ. CXCR3 is
involved in tubulointerstitial injury in human glomerulonephritis. Am J
Path.2004, 164: 635-49
5,5
26. Eis V, Luckow B, Vielhauer V, Siveke JT, Linde Y, Segerer S, De
Lema GP, Cohen CD, Kretzler M, Mack M, Horuk R, Murphy PM, Gao
JL, Hudkins KL, Alpers CE, Grone HJ, Schlondorff D, Anders HJ.
Chemokine Receptor CCR1 but not CCR5 mediates leukocyte
recruitment and subsequent Renal Fibrosis after Unilateral Ureteral
Obstruction. J Am Soc Nephrol. 2004, 15: 337-47
7,1
27. Mühlfeld AS, S Segerer, Hudkins KL, Farr AG, Bao L, Kraus D,
Holers VM, Quigg R, Alpers CE. Overexpression of complement inhibitor
Crry does not prevent cryoglobulin-associated membranoproliferative
glomerulonephritis. Kidney Int 2004, 65:1214-1223
4,9
28. Anders HJ, Belemezova E, Eis V, Segerer S, Vielhauer V, Perez
de Lema G, Kretzler M, Cohen CD, Frink M, Horuk R, Hudkins KL,
Alpers CE, Mampaso F, Schlöndorff D. Late onset of treatment with a
chemokine receptor CCR1 antagonist prevents progression of lupus
nephritis in MRL(Fas)lpr mice. J Am Soc Nephrol. 2004, 15:1504-13
7,1
29. Vielhauer V, Berning E, Eis V, Kretzler M, Segerer S, Strutz F,
Horuk R, Grone HJ, Schlondorff D, Anders HJ. CCR1 blockade reduces
interstitial inflammation and fibrosis in mice with glomerulosclerosis and
nephrotic syndrome. Kidney Int. 2004, 66: 2264-78, 2004
4,9
30. Bruhl H, Vielhauer V, Weiss M, Mack M, Schlondorff D, Segerer
S: Expression of DARC, CXCR3 and CCR5 in giant cell arteritis.
Rheumatology 2005, 44: 309-13
4,0
31. Ninichuk V, Gross O, Reichel C, Khandoga A, Pawar RD, Ciubar
R, Segerer S, Belemezova E, Radomska E, Luckow B, de Lema GP,
Murphy PM, Gao JL, Henger A, Kretzler M, Horuk R, Weber M,
Krombach F, Schlondorff D, Anders HJ. Delayed C Chemokine Receptor
Receptor 1 blockade prolongs survival in collagen 4A3-deficient mice
with Alport disease. J Am Soc Nephrol 2005, 16: 977-985
7,1
32. Segerer S, Böhmig GA, Exner M, Kerjaschki D, Regele H,
Schlöndorff D. Role of CXCR3 in cellular but not humoral renal allograft
rejection Transplant Int 2005, 18: 676-680
2,3
33. Patole PS, Grone HJ, Segerer S, Ciubar R, Belemezova E,
Henger A, Kretzler M, Schlondorff D, Anders HJ. Viral Double-Stranded
RNA aggravates lupus nephritis through Toll-Like Receptor 3 on
glomerular mesangial cells and antigen-presenting cells. J Am Soc
Nephrol 2005, 16:1326-1338
7,1
34. Notohamiprodjo M, Segerer S, Huss R, Hildebrandt B, Soler D,
Djafarzadeh R, Buck W, Nelson PJ, von Luettichau I. CCR10 is
expressed in cutaneous T-cell lymphoma. Int J Cancer. 2005, 115:641-7
4,6
35. Gross O, Koepke ML, Beirowski B, Schulze-Lohoff E, Segerer S,
Weber M. Nephroprotection by antifibrotic and anti-inflammatory effects
of the vasopeptidase inhibitor AVE7688. Kidney Int 2005, 68:456-63
4,9
36. de Lema GP, Maier H, Franz TJ, Escribese M, Chilla S, Segerer
S, Camarasa N, Schmid H, Banas B, Kalaydjiev S, Busch DH, Pfeffer K,
Mampaso F, Schlondorff D, Luckow B. Chemokine receptor Ccr2
deficiency reduces renal disease and prolongs survival in MRL/lpr lupus-
prone mice. J Am Soc Nephrol. 2005, 16:3592-3601
7,1
37. Pawar RD, Patole PS, Zecher D, Segerer S, Kretzler M,
Schlondorff D, Anders HJ. Toll-Like Receptor-7 modulates immune
complex glomerulonephritis. J Am Soc Nephrol. 2006, 17:141-149
7,1
38. Patole PS, Schubert S, Hildinger K, Khandoga S, Khandoga A,
Segerer S, Henger A, Kretzler M, Werner M, Krombach F, Schlondorff D,
Anders HJ. Toll-like receptor-4: renal cells and bone marrow cells signal
for neutrophil recruitment during pyelonephritis.
Kidney Int 2005, 68: 2582-2587
4,9
39. Segerer S, Hoffmann U, Rummele P, Kruger B, Pietrzyk M,
Hofstadter F, Banas B, Kramer BK. Expression of the chemokine
receptor CXCR3 in human renal allografts-a prospective study. Nephrol
Dial Transplant. 2006, 21: 1373-1381
3,2
40. Hoffmann U, Banas B, Kruger B, Pietrzyk M, Obed A, Segerer S,
Kammerl M, Rummele P, Riegger GA, Kramer BK. Expression of
cyclooxygenase-1 and cyclooxygenase-2 in human renal allograft
rejection- a prospective study. Transpl Int 2006, 19:203-212
2,3
41. Segerer S, Henger A, Schmid H, Kretzler M, Draganovici D,
Brandt U, Noessner E, Nelson PJ, Kerjaschki D, Schlondorff D, Regele
H. Expression of the chemokine receptor CXCR1 in human glomerular
diseases Kidney Int 2006, 69: 1765-1773
4,9
42. Ninichuk V, Gross O, Segerer S, Hoffmann R, Radomska E,
Buchstaller A, Huss R, Akis N, Schlondorff D, Anders HJ. Multipotent
mesenchymal stem cells reduce interstitial fibrosis but do not delay
progression of chronic kidney disease in collagen4A3-deficient mice.
Kidney Int. 2006, 70:121-129
4,9
43. Patole PS, Pawar RD, Lech M, Zecher D, Schmidt H, Segerer S,
Ellwart A, Henger A, Kretzler M, Anders HJ. Expression and regulation
of Toll-like receptors in lupus-like immune complex glomerulonephritis of
MRL-Fas(lpr) mice. Nephrol Dial Transplant. 2006, 21: 3062-3073
3,2
44. von Luettichau I, Nathrath M, Burdach S, Huss R, Segerer S,
Nelson PJ. Mononuclear infiltrates in osteosarcoma and chemokine
receptor expression. Clin Cancer Res. 2006, 12:5253-5254
6,3
45. Hoffmann U, Banas B, Kruger B, Banas M, Bergler T, Boger C,
Kammerl M, Obed A, Rummele P, Segerer S, Riegger GA, Kramer BK.
SDF-1 expression is elevated in chronic human renal allograft rejection.
Clin Transplant. 2006, 20: 712-718
1,9
46. Pawar RD, Patole PS, Ellwart A, Lech M, Segerer S, Schlondorff
D, Anders HJ. Ligands to Nucleic Acid-Specific Toll-Like Receptors and
the onset of Lupus nephritis J Am Soc Nephrol. 2006, 17:3365-3373
7,1
47. Heller F, Cohen CD, Lindenmeyer MT, Brandt U, Draganovici D,
Fischereder M, Matthias Kretzler, Anders HJ, Sitter T, Kerjaschki D,
Regele H, Schlöndorff D, Segerer S. The contribution of B cells to renal
interstitial inflammation. Am J Pathol. 2007, 170:457-468
5,5
48. Koepke ML, Weber M, Schulze-Lohoff E, Beirowski B, Segerer S,
Gross O. Nephroprotective effect of the HMG-CoA-reductase inhibitor
cerivastatin in a mouse model of progressive renal fibrosis in Alport
syndrome. Nephrol Dial Transplant. 2007, 22: 1720-1729
3,2
49. Mayer V, Hudkins KL, Heller F, Schmid H, Kretzler M, Brandt U,
Anders HJ, Regele H, Nelson PJ, Alpers CE, Schlöndorff D, Segerer S.
Expression of the chemokine receptor CCR1 in human renal allografts.
Nephrol Dial Transplant. 2007, 22:1720-1729
3,2
50. Pawar RD, Ramanjaneyulu A, Kulkarni OP, Lech M, Segerer S,
Anders HJ. Inhibition of Toll-like receptor (TLR)-7 or TLR7 plus TLR9
prevents glomerulonephritis and lung injury in experimental lupus. J Am
Soc Nephrol. 2007, 18:1721-1731
7,1
51. Segerer S, Djafarzadeh R, Gröne HJ, Weingart C, Kerjaschki D,
Weber C, Kungl AJ, Regele H, Proudfoot AEI, Nelson PJ. Selective
binding and presentation of CCL5 by discrete tissue microenvironments
during renal inflammation. J Am Soc Nephrol. 2007, 18:1835-1844
7,1
52. Patole PS, Pawar RD, Lichtnekert J, Leck M, Kulkarni O,
Ramanjaneyulu A, Segerer S, Anders HJ. Coactivation of Toll-like
receptor-3 and -7 in immune complex glomerulonephritis. J Autoimmun.
2007, 29:52-59
3,4
53. Ninichuk V, Khandoga AG, Segerer S, Loetscher P, Schlapbach
A, Revesz L, Feifel R, Khandoga A, Krombach F, Nelson PJ, Schlondorff
D, Anders HJ. The role of interstitial macrophages in nephropathy of
type 2 diabetic db/db mice. Am J Pathol. 2007, 170:1267-76
5,5
54. Derfuss T, Segerer S, Herberger S, Sinicina I, Hufner K, Ebelt K,
Knaus HG, Steiner I, Meinl E, Dornmair K, Arbusow V, Strupp M, Brandt
T, Theil D. Presence of HSV-1 Immediate Early Genes and Clonally
Expanded T-cells with a Memory Effector Phenotype in Human
Trigeminal Ganglia. Brain Pathol. 2007, 17:389-98
3,7
55. von Luettichau I, Segerer S, Wechselberger A, Notohamiprodjo
M, Nathrath M, Kremer M, Henger A, Djafarzadeh R, Burdach S, Huss
R, Nelson PJ. A complex pattern of chemokine receptor expression is
seen in osteosarcoma. BMC Cancer. 2008, 8: 23
2,7
56. Kulkarni O, Pawar RD, Purschke W, Eulberg D, Selve N,
Buchner K, Ninichuk V, Segerer S, Vielhauer V, Klussmann S, Anders
HJ. Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in
MRL-(Fas)lpr mice. J Am Soc Nephrol. 2007, 18: 2350-2358
7,1
57. Ninichuk V, Clauss S, Kulkarni O, Schmid H, Segerer S,
Radomska E, Eulberg D, Buchner K, Selve N, Klussmann S, Anders HJ.
Late Onset of Ccl2 Blockade with the Spiegelmer mNOX-E36-3'PEG
prevents glomerulosclerosis and improves glomerular filtration rate in
db/db mice. Am J Pathol. 2008, 172: 628-37
5,5
58. Segerer S, Heller F, Lindenmeyer MT, Schmid H, Cohen CD,
Draganovici D, Mandelbaum J, Nelson PJ, Gröne HJ, Gröne EF, Figel
AM, Nössner E, Schlöndorff D. Compartment specific expression of
dendritic cell markers in human glomerulonephritis. Kidney Int. 2008,
74:37-46
4,9
59. Lehmann I, Fischereder M, Böhmig GA, Regele H, Exner M,
Raith M, Weiss N, Segerer S. The source matters: No impact of the
CCL2/MCP-1-2518G polymorphism of the donor on renal allograft
outcome during the first year of transplantation. Transplant Proc. 2008,
40:3359-3361
1,0
60. Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M,
Middleton J, Richmond A, Graham G, Segerer S, Nibbs R, Rot A. Duffy
antigen/receptor for chemokines transports chemokines and supports
their pro-migratory activity in vitro and in vivo. Nature Immunol 2009,
10:101-108
26
61. Clauss S, Gross O, Kulkarni O, Avila-Ferrufino A, Radomska E,
Segerer S, Eulberg D, Klussmann S, Anders HJ. Ccl2/Mcp-1 blockade
reduces glomerular and interstitial macrophages but does not ameliorate
renal pathology in collagen4A3-deficient mice with autosomal recessive
Alport nephropathy. J Pathol. 2008, 218: 40-47
5,8
62. Lichtnekert J, Vielhauer V, Zecher D, Kulkarni OP, Clauss S,
Segerer S, Hornung V, Mayadas TN, Beutler B, Akira S, Anders HJ.
Dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif
in immune complex glomerulonephritis. Am J Physiol Renal Physiol.
2009, 296: F867-874
4,5
63. Pawar RD, Castrezana-Lopez L, Allam R, Kulkarni OP, Segerer
S, Radomska E, Meyer TN, Schwesinger CM, Akis N, Gröne HJ, Anders
HJ. Bacterial lipopeptide triggers massive albuminuria in murine lupus
nephritis by activating Toll-like receptor 2 at the glomerular filtration
barrier. Immunology. 200, 128(1 Suppl):e206-221
3,4
64. Kulkarni O, Eulberg D, Selve N, Zöllner S, Allam R, Pawar RD,
Pfeiffer S, Segerer S, Klussmann S, Anders HJ. Anti-Ccl2 Spiegelmer
permits 75% dose reduction of cyclophosphamide to control diffuse
proliferative lupus nephritis and pneumonitis in MRL-Fas(lpr) mice. J
Pharmacol Exp Ther. 2009, 328: 371-377
4,0
65. Vielhauer V, A Ramanjaneyulu, MT Lindenmeyer, CD Cohen,
Draganovici D, Mandelbaum J, Eltrich N, Nelson PJ, Anders HJ,
Pruenster M, Rot A, Schlöndorff D, Segerer S. Efficient renal recruitment
of macrophages and T cells in mice lacking the Duffy antigen/receptor
for chemokines. Am J Path 2009, 175:119-131
5,9
66. Segerer S, Johnson Z, Rek A, Baltus T, von Hundelshausen P,
Kungl AJ, Proudfoot AEI, Weber C, Nelson PJ. The basic residue cluster
55
KKWVR59
in CCL5 is required for in vivo biologic function Mol Immunol
2009, 46: 2533-2538
3
67. Lech M, Avila-Ferrufino A, Allam R, Segerer S, Khandoga A,
Krombach F, Garlanda C, Mantovani A, Anders HJ. Resident dendritic
cells prevent postischemic acute renal failure by help of single
immunoglobulin interleukin-1 receptor-related protein. J Immunol 2009,
183:4109-4118
6
68. Sayyed SG, Hägele H, Kulkarni OP, Endlich K, Segerer S,
Eulberg D, Klussmann S, Anders HJ. Podocytes produce homeostatic
chemokine stromal cell-derived factor-1/CXCL12, which contributes to
glomerulosclerosis, podocyte loss and albuminuria in a mouse model of
type 2 diabetes. Diabetologia. 2009, 52:2445-2454
6,4
69. Geleff S, Draganovici D, Jaksch P, Segerer S. The role of
chemokine receptors in acute lung allograft rejection. Eur Resp J,
35:167-175; 2010
5,5
70. Sostak P, Padovan CS, Eigenbrod S, Roeber S, Segerer S,
Schankin C, Siegert S, Saam T, Theil D, Kolb HJ, Kretzschmar H,
Straube A. Cerebral angiitis in four patients with chronic GVHD. Bone
Marrow Transplant. 2010, 45: 1181-1188
3,4
71. Neusser MA, Lindenmeyer MT, Moll AG, Segerer S, Edenhofer I,
Sen K, Stiehl DP, Kretzler M, Gröne HJ, Schlöndorff D, Cohen CD.
Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Am J
Pathol. 2010, 176:594-607
5,9
72. Jedlicka J, Soleiman A, Draganovici D, Mandelbaum J, Ziegler U,
Regele H, Wüthrich RP, Gross O, Anders HJ, Segerer S. Interstitial
inflammation in Alport syndrome. Hum Pathol. 2010, 41: 582-593
3,3
73. Neusser MA, Kraus AK, Regele H, Cohen CD, Fehr T, Kerjaschki
D, Wüthrich RP, Penfold ME, Schall T, Segerer S. The chemokine
receptor CXCR7 is expressed on lymphatic endothelial cells during renal
allograft rejection. Kidney Int. 2010, 77: 801-808
6,4
74. Bergamin B, Senn O, Corsenca A, Dutkowski P, Weber M,
Wüthrich RP, Segerer S, Pechula Thut M. Finding the right position: a
three year, single-center experience with the “self-locating” catheter.
Perit Dial Int. 2010, 30: 519-23
1,9
75. Gross O, Girgert R, Beirowki B, Kretzler M, Kang HG, Kruegel J,
Miosge N, Busse AC, Segerer S, Vogel WF, Müller GA, Weber M. Loss
of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV
collagen disease Matrix Biol 2010, 29: 346-56
3,6
76. Hoffmann U, Bergler T, Segerer S, Rümmele P, Krüger B, Banas
MC, Reinhold S, Banas B, Krämer BK. Impact of chemokine receptor
CX3CR1 in human renal allograft rejection. Transpl Immunol. 2010, 23:
204-8
2,4
77. Lin M, Yin N, Murphy B, Medof ME, Segerer S, Heeger PS,
Schröppel B: Immune cell-derived c3 is required for autoimmune
diabetes induced by multiple low doses of streptozotocin. Diabetes.
2010, 59: 2247-52
8,5
78. Tian Y, Chen J, Gaspert A, Segerer S, Clavien PA, Wüthrich RP,
Fehr T. Kidney Transplantation in Mice Using Left and Right Kidney
Grafts. J Surg Res. 2010, 163: e91-7
2,2
79. Braun N, Alscher DM, Fritz P, Edenhofer I, Kimmel M, Gaspert A,
Reimold F, Bode-Lesniewska B, Ziegler U, Biegger D, Wüthrich RP,
Segerer S. Podoplanin-positive cells are a hallmark of encapsulating
peritoneal sclerosis. Nephrol Dial Transplant 2011, 26:1033-41
3,3
80. Neusser MA, Lindenmeyer MT, Edenhofer I, Gaiser S., Kretzler
M, Regele H, Segerer S, Cohen CD. Intrarenal production of B cell
survival factors in human lupus nephritis Mod. Pathol 2011, 24: 98-107
4,4
81. Lin M, Murphy B, Medof ME, Segerer S, Heeger PS, Schröppel
B. Response to Comment on: Lin et al. Immune Cell-Derived C3 Is
Required for Autoimmune Diabetes Induced by Multiple Low Doses of
Streptozotocin. Diabetes. 2011, 59:2247-2252
8,5
82. Starke A, Lindenmeyer MT, Segerer S, Neusser MA, Rüsi B,
Schmid DM, Cohen CD, Wüthrich RP, Fehr T, Waeckerle-Men Y. Renal
tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses.
Kidney Int. 2010, 78: 38-47
6,4
83. Welsh-Bacic D, Lindenmeyer M, Cohen CD, Draganovici D,
Mandelbaum J, Edenhofer I, Ziegler U, Regele H, Wüthrich RP, Segerer
S: Expression of the chemokine receptor CCR6 in human renal
inflammation. Nephrol Dial Transplant. 2011, 26: 1211-20
3,3
84. Figel AM, Brech D, Prinz PU, Lettenmeyer UK,Hosse J, Turqueti-
Neves A, Mysliwietz J, Anz D, Rieth N, Muenchmeier N, Buchner A,
Porubsky S, Siegert SI, Segerer S, Nelson PJ, Noessner E: Human
renal cell carcinoma induces a dendritic cell subset that uses T-cell
crosstalk for tumor-permissive milieu alterations. Am J Pathol 2011, 179:
436-451
5,9
85. Raina S, Honer M, Krämer SD, Liu Y, Wang X, Segerer S,
Wüthrich RP, Serra AL. Anti-VEGF antibody treatment accelerates
polycystic kidney disease. Am J Physiol Renal Physiol. 2011, 301: F773-
83
3,8
86. Cippa PE, Kraus AK, Edenhofer I, Segerer S, Chen J, Hausmann
M, Liu Y, Guimezanes A, Bardwell PD, Wüthrich RP, Fehr T: The BH3-
mimetic ABT-737 inhibits allogeneic immune responses. Transplant Int.
2011, 24: 722–732
3,2
87. Sen K, Lindenmeyer MT, Gaspert A, Eichinger F, Neusser MA,
Kretzler M, Segerer S, Cohen CD. Periostin is induced in glomerular
injury and expressed de novo in interstitial renal fibrosis. Am J Pathol.
2011, 179: 1756-67
5,2
88. Seleznik GM, Reding T, Romrig F, Saito Y, Mildner A, Segerer S,
Sun LK, Regenass S, Lech M, Anders HJ, McHugh D, Kumagi T, Hiasa
Y, Lackner C, Haybaeck J, Angst E, Perren A, Balmer ML, Slack E,
MacPherson A, Manz M, Weber A, Browning J, Arkan MC, Rülicke T,
Aguzzi A, Prinz M, Graf R, Heikenwalder M: A Lymphotoxin-driven, IL17-
independent pathway to autoimmune pancreatitis and systemic
autoimmunity Gastroenterology. 2012, 143: 1361-74
12,0
89. Berthier CC, Gonzalez-Rivera T, Bethunaickan R, Nair V,
Ramanujam M, Zhang W, Bottinger EP, Segerer S, Davidson A, Kretzler
M. Cross-species transcriptional network analysis defines shared
inflammatory responses in murine and human lupus nephritis. J
Immunol. 2012, 189: 988-1001
5.7
90. Braun N, Fritz P, Ulmer C, Latus J, Kimmel M, Biegger D, Ott G,
Reimold F, Thon KP, Dippon J, Segerer S, Alscher DM. Histological
criteria for encapsulating peritoneal sclerosis - a standardized approach.
PLOS ONE. 2012, 7: e48647
4,1
91. Braun N, Alscher MD, Fritz P, Latus J, Edenhofer I, Reimold F,
Alper SL, Kimmel M, Biegger D, Lindenmeyer M, Cohen CD, Wüthrich
RP, Segerer S: The Spectrum of Podoplanin Expression in
Encapsulating Peritoneal Sclerosis. PLOS ONE. 2012, 7: e48647
4.1
92. Latus J, Ulmer C, Fritz P, Rettenmaier B, Biegger D, Lang T, Ott
G, Kimmel M, Steurer W, Alscher MD, Segerer S, Braun N. Phenotypes
of Encapsulating Peritoneal Sclerosis –Macroscopical Appearance,
Histological Findings and Outcome. Perit Dial Int 2013, 33: 495-502
2.1
93. Cippà PE, Kamarashev J, Chen J, Kraus AK, Segerer S,
Feldmeyer L, Fehr T. Synergistic Bcl-2 inhibition by ABT-737 and
cyclosporine A. Apoptosis. 2013, 18: 315-23
4.8
94. Reimold FR, Braun N, Zsengellér ZK, Stillman IE, Karumanchi
SA, Toka HR, Latus J, Fritz P, Biegger D, Segerer S, Alscher MD,
Bhasin MK, Alper SL: Transcriptional Patterns in Peritoneal Tissue of
Encapsulating Peritoneal Sclerosis, a Complication of Chronic Peritoneal
Dialysis PLOS ONE. 2013, 8: e56389
4.1
95. Braun N, Sen K, Alscher MD, Fritz P, Kimmel M, Morelle J, Goffin
E, Jörres A, Wüthrich RP, Cohen CD, Segerer S. Periostin- a
matricellular protein involved in peritoneal injury during peritoneal
dialysis Perit Dial Int 2013, 33: 515-28
2.1
96. Kraus AK, Cippá PE, Gaspert A, Chen J, Edenhofer I, Wüthrich
RP, Lindenmeyer M, Segerer S, Fehr T. Absence of donor CD40
protects renal allograft epithelium and preserves renal function. Transpl
Int. 2013, 26: 535-44
3.2
97. Wang X, Zhang S, Yang L, Spichtig D, Kapoor S, Koepsell H,
Mohebbi N, Segerer S, Serra AL, Devuyst O, Mei C, Wüthrich RP:
Glycosuria induction via phlorizin-mediated SGLT inhibition prevents
disease progression in Han:SPRD rats with polycystic kidney disease.
Kidney Int. 2013, 84: 962-8
7.9
98. Latus J, Goffin E, Schroeder JA, Fritz P, Ott G, Ulmer C, Steurer
W, Kimmel M, Biegger D, Segerer S, Alscher MD, Braun N. Gadolinium
deposits and delayed peritoneal clearance in patients on peritoneal
dialysis and in patients with encapsulating peritoneal sclerosis Perit Dial
Int. 2014, 34: 561-565
2.1
99. D. Spichtig, H. Zhang, N. Mohebbi, I. Pavik, K. Petzold, G.
Stange, L Saleh, I. Edenhofer, S. Segerer, O. Devuyst, J. Biber, P.
Jaeger, AL. Serra, CA. Wagner: Renal Expression of FGF23 and
Peripheral Resistance to elevated FGF23 in rodent models of Polycystic
Kidney Disease. Kidney Int 2014, 85: 1340-50
7.9
100. Seeger H, Braun N, Latus J, Alscher MD, Fritz P, Edenhofer I,
Biegge D, Lindenmeier M, Wüthrich RP, Segerer S: Platelet-derived
growth factor receptor β (PDGFRβ) expression in human peritoneum.
Nephron Clin Pract. 2014; 128: 178-84
1.7
101. Latus J, Habib SM, Kitterer D, Korte MR, Ulmer C, Fritz P, Davies
S, Lambie M, Alscher MD, Betjes MG, Segerer S, Braun N; on behalf of
the European EPS study group. Histological and clinical findings in
patients with post-transplantation and classical encapsulating peritoneal
sclerosis: a European multicenter study. PLoS One. 2014, 9: e106511
3.5
102. Latus J, Schwab M, Tacconelli E, Pieper FM, Wegener D,
Rettenmaier B, Schwab A, Hoffmann L, Dippon J, Müller S, Fritz P, Zakim
D, Segerer S, Kitterer D, Kimmel M, Gußmann K, Priwitzer M, Mezger B,
Walter-Frank B, Corea A, Wiedenmann A, Brockmann S, Pöhlmann C,
Alscher MD, Braun N. Defining risk for severe acute kidney injury in 456
patients with Hantavirus induced Nephropathia Epidemica. Nephrol,
Dial, Transplant 2015; 30: 245-51
3.5
103. Latus J, Schwab M, Tacconelli E, Pieper FM, Wegener D,
Rettenmaier B, Schwab A, Hoffmann L, Dippon J, Müller S, Fritz P, Zakim
D, Segerer S, Kitterer D, Priwitzer M, Mezger B, Walter-Frank B, Corea
A, Wiedenmann A, Brockmann S, Pöhlmann C, Alscher MD, Braun N.
Clinical course and long-term outcome in 456 patients with Hantavirus-
induced Nephropathia epidemica, Germany, 2001-2012. Emerg Infect
Dis. 2015; 21: 76-83
7.3
104. Latus J, Kitterer D, Segerer S, Artunc F, Alscher MD, Braun N.
Severe thrombocytopenia in hantavirus-induced nephropathia
epidemica. Infection. Infection. 2015; 43: 83-7
2.9
105. Latus J, Kitterer D, Dippon J, Müller S, Artunc F, Segerer S,
Alscher MD, Braun N. Polyuria in hantavirus infection reflects disease
severity and is associated with prolonged hospital stay – a systematic
analysis of 335 patients from Southern Germany. Nephron Exp Nephrol.
2015 [epub ahead of print]
1.7
106. Thalhammer C, Segerer S, Augustoni M, Jacomella V, Clemens
RK, Wüthrich RP, Amann-Vesti BR, Husmann M. Acute effects of
haemodialysis on central venous and arterial pressure characteristics.
Nephrology (Carlton). 2015; 20: 91-5
1.9
107. Kapoor S, Rodriguez D, Riwanto M, Edenhofer I, Segerer S,
Mitchell K, Wüthrich RP. Effect of Sodium-Glucose Cotransport Inhibition
on Polycystic Kidney Disease Progression in PCK Rats. PLoS One.
2015;10(4): e0125603
3.5
108. Latus J, Kitterer D, Segerer S, Artunc F, Alscher MD, Braun N.
Determination of procalcitonin levels in patients with nephropathia
epidemica - a useful tool or an unnecessary diagnostic procedure?
Kidney Blood Press Res. 2015; 40: 22-30
2.1
109. Seleznik G, Seeger H, Bauer J, Fu K, Czerkowicz J, Papandile A,
Poreci U, Rabah D, Ranger A, Cohen CD, Lindenmeyer M, Chen J,
Edenhofer I, Anders HJ, Lech M, Wüthrich RP, Ruddle NH, Moeller MJ,
Kozakowski N, Regele H, Browning JL, Heikenwalder M, Segerer S.
The lymphotoxin β receptor is a potential therapeutic target in renal
inflammation. Kidney Int. 2015 [epub ahead of print]
8.5
110. Kitterer D, Latus J, Ulmer C, Fritz P, Biegger D, Ott G, Alscher
MD, Witowski J, Kawka E, Joerres A, Seeger H, Segerer S, Braun N.
Activation of Nuclear Factor of Activated T Cells 5 in the peritoneal
membrane of uremic patients. Am J Physiol Renal Physiol. 2015, 308:
F1247-58
3.2
111. Kitterer D, Gürzing K, Segerer S, Alscher MD, Amann K, Braun
N, Latus J. Diagnostic impact of percutaneous renal biopsy. Clin
Nephrol. 2015, 84: 311-22
1.1
112. Kitterer D, Segerer S, Steurer W, Dippon J, Geissler A, Ulmer C,
Braun N, Alscher MD, Latus J. C-reactive protein levels in combination
with abdominal CT scans is a useful tool to predict the macroscopic
appearance in late-stage EPS patients prior to surgery. Int J Nephrol
Renovasc Dis. 2015, 8: 83-90
113. Kitterer D, Artunc F, Segerer S, Alscher MD, Braun N, Latus J.
Evaluation of lipase levels in patients with nephropathia epidemica--no
evidence for acute pancreatitis. BMC Infect Dis. 2015, 15: 286
2.6
114. Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S,
Cohen CD, Neuhauss SC, Loffing J. The Rho-GTPase binding protein
IQGAP2 is required for the glomerular filtration barrier. Kidney Int. 2016
[epub ahead of print]
8.5
115. Kitterer D, Segerer S, Alscher MD, Braun N, Latus J. Puumala
Hantavirus-Induced Hemorrhagic Fever with Renal Syndrome must be
considered across the borders of nephrology to avoid unnecessary
diagnostic procedures. PLoS One. 2015, 10: e0144622.
3.2
116. Prange JA, Bieri M, Segerer S, Burger C, Kaech A, Moritz W,
Devuyst O. Human proximal tubule cells form functional microtissues.
Pflugers Arch. 2015 [Epub ahead of print]
4.1
117. Rodriguez D, Kapoor S, Edenhofer I, Segerer S, Riwanto M,
Kipar A, Yang M, Mei C, Wüthrich RP. Inhibition of Sodium-
GlucoseCotransporter 2 with Dapagliflozin in Han: SPRD Rats with
Polycystic Kidney Disease. Kidney Blood Press Res. 2015;40: 638-47
2.1
118. Riwanto M, Kapoor S, Rodriguez D, Edenhofer I, Segerer S,
Wüthrich RP. Inhibition of Aerobic Glycolysis Attenuates Disease
Progression in Polycystic Kidney Disease. PLoS One. 2016 11:
e0146654
3.2
119. Kraus AK, Chen J, Edenhofer I, Ravens I, Gaspert A, Cippà PE,
Mueller S, Wuthrich RP, Segerer S, Bernhardt G, Fehr T. The Role of T
Cell Costimulation via DNAM-1 in Kidney Transplantation. PLoS One.
2016, 11: e0147951
3.2
Fallbeschreibungen
120. Meister P, Segerer W, Segerer S, Auer K. Interstitielle Nephritis
mit akutem Nierenversagen bei Ascaris-lumbricoides-Infektion.
Pathologe 1995, 16: 434-438
0,3
121. Segerer S, Feth M, Segerer W. Fieber, Diarrhoe und akutes
polyurisches Nieren-versagen-Hantavirusinfektion, Nephropathia
epidemica. Spektrum der Nephrologie 1997, 2
122. Segerer S, Dietz-Laukemann P, Schattenkirchner M. RS3PE-
Syndrom. Z Rheumatologie 1999, 58: 35-38
0,7
123. Segerer S, Mühlhöfer A, Gross M, Kellner W, Spengel FA,
Pfeifer J. Angina abdominalis- Duplexsonographische Diagnose und
perkutane Revaskularisierung VASA 200, 29, 141-145
0,5
124. Schröppel B, Segerer S, Keuneke C, Cohen CD, Schlöndorff D.
Hyponatremic encephalopathy after preparation for colonoscopy.
5,9
Gastrointestinal Endoscopy 2001, 53: 527-529
125. Schwegler I, Segerer S. A painful fistula. Circulation. 2011, 123:
2606
14.6
126. Schleich A, Gerber L, Wüthrich RP, Segerer S. Peri-renal
Hematoma After Intraperitoneal Cefazolin Treatment for Peritonitis. Perit
Dial Int. 2011, 31: 505-507
1.9
127. Kocher C, Segerer S, Schleich A, Caduff R, Wyler LG, Müller V,
Beck B, Blum J, Kamarachev J, Mueller NJ. Skin lesions, malaise, and
heart failure in a renal transplant recipient. Transpl Infect Dis. 2012, 14:
391-7
2.0
128. Cippà PE, Auinger K, Wüthrich RP, Segerer S. An infectious
cause of acute kidney injury with low serum potassium. BMJ Case Rep.
2016 [epub ahead of print]
Übersichtsarbeiten
129. Floege J, S Segerer, J Schäffer, KM Koch. Langzeitbetreuung
von Dialysepatienten II. 2-Mikroglobulin assoziierte Amyloidose und
erworbene zystische Nierenerkrankung. Internist 1999, 40: 64-69
0,3
130. Schlöndorff D, S Segerer. Pathogenesis of glomerulonephritis, a
perspective from the last 30 years. J Nephrology 1999, 12 suppl. 2,
S131-141
1,1
131. Segerer S, PJ Nelson, D Schlöndorff. Chemokines, chemokine
receptors, and renal disease: from basic science to pathophysiologic
and therapeutic studies. J Am Soc Nephrol 2000, 11: 152-176
7,1
132. Segerer S. The Role of chemokines and chemokine receptors in
progressive renal diseases. Am J Kidney Dis. 2003, 41(S1): S15-S18
4
133. Segerer S, Alpers CE. Chemokines and chemokine receptors in
renal pathology. Curr Opin Nephrol Hypertens. 2003, 12: 243-249
4,1
134. Segerer S, Nelson PJ. Chemokines in renal diseases.
ScientificWorldJournal 2005, 5: 835-844
135. Segerer S, Schlöndorff D. Role of chemokines for the localization
of leukocytes subsets in the kidney. Semin Nephrol 2007, 27: 260-74
1,9
136. Segerer S, Schlöndorff D. B cells and tertiary lymphoid organs in
renal inflammation. Kidney Int 2008, 73: 533-7
4,9
137. Gross O, Borza DB, Anders HJ, Licht C, Weber M, Segerer S,
Torra R, Gubler MC, Heidet L, Harvey S, Cosgrove D, Lees G, Kashtan
C, Gregory M, Savige J, Ding J, Thorner P, Abrahamson DR, Antignac
C, Tryggvason K, Hudson B, Miner JH. Stem cell therapy for Alport
syndrome: the hope beyond the hype. Nephrol Dial Transplant. 2009,
24: 731-4
3,2
138. Segerer S, Jedlicka J, Wüthrich R. Atypical chemokine receptors
in renal inflammation. Nephron Exp Nephrol 2010, 115: e89-e95
2,0
139. Wüthrich RP, Segerer S. Mechanismen der renalen
Salzregulation und ihre medikamentöse Beeinflussung. Cardiovasc 5: 6-
10, 2009
140. Lindenmeyer M, Noessner E, Nelson PJ, Segerer S. Dendritic
cells in experimental renal inflammation - part I. Nephron Exp Nephrol.
2011, 119: e83-90
2.7
141. Noessner E, Lindenmeyer M, Nelson PJ, Segerer S. Dendritic
Cells in Human Renal Inflammation - Part II. Nephron Exp Nephrol. 2011
119: e91-8
2.7
142. Seeger H, Bonani M, Segerer S. The role of lymphatics in renal
inflammation. Neprol Dial Transplant. 2012 27:2634-41
3.6
143. Thalhammer C, Pfammatter T, Segerer S. Vascular accesses for
hemodialysis - an Update. Vascular accesses for hemodialysis - an
0.9
update. Vasa. 2013, 42: 252-6
144. Thalhammer C, Segerer S. Hemodialysis vascular access. Dtsch
Med Wochenschr 2014, 139: 1562-4
0.7
145. Seeger H, Segerer S. The role of lymphatic vessels in renal
injury. J Clin Cell Immunol 2014, 5: 255
146. Seeger H, Kitterer D, Latus J, Alscher MD, Braun N, Segerer S.
The potential role of NFAT5 and osmolarity in peritoneal injury. Biomed
Res Int. 2015: 578453.
Buchkapitel:
147. Nelson PJ, Segerer S, Schlöndorff D. Chemoattractants and chemokines in renal
disease. In: Immunologic renal diseases. edn 2. Edited by Neilson EG, Couser WG.
Lippincott Williams & Wilkins: 2001, 521-550
148. Segerer S, F. Strutz, M. Kretzler, D. Schlöndorff. Tissue injury in renal diseases In:
Diseases of the Kidney and Urinary Tract. Edited by Schrier RW, 2006
149. Mühlfeld A, Segerer S, Alpers C. HIV associated thrombotic microangiopathy
Mühlfeld A, Segerer S, Alpers C. HIV associated thrombotic microangiopathy. In: AIDS and
Heart Disease. Edited by Watson RR. Marcel Dekker: 2004, 71-83
150. Nelson PJ, Segerer S, Schlondorff D: Chemokines in Transplantation Biology. In: The
Receptors: The Chemokine Receptors Edited by: J. K. Harrison, N. W. Lukacs: 2007
Zürich, den 15.03.2016 Stephan Segerer

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Literatur Segerer 03 2016 final

  • 1. Originalarbeiten: Impact factor: 1. Schröppel B, Fischereder M, Wiese P, Segerer S, Huber S, Kretzler M, Heiss P, Sitter T, Schlöndorff D: Expression of glucose transporters in human peritoneal mesothelial cells. Kidney Int 1998, 53: 1278-1287 4,9 2. Segerer S, Meister P: Die erworbene, zystische Nierenerkrankung bei chronischen Dialysepatienten: eine retrospektive Studie an 125 Autopsien (Teil 1, Zysten). Pathologe 1998, 19: 292-298 0,3 3. Segerer S, Meister P: Die erworbene, zystische Nierenerkrankung bei chronischen Dialysepatienten: eine retrospektive Studie an 125 Autopsien (Teil 2, Tumoren). Pathologe 1998, 19: 368- 372 0,3 4. Segerer S, Bogner J, Walli R, Loch O, Goebel FD. Hyperlipidemia under treatment with proteinase inhibitors. Infection 1999, 27: 77-81 1,6 5. Segerer S, Mack M, Regele H, Kerjaschki D, Schlöndorff D. Expression of the chemokine receptor CCR5 in human kidney diseases. Kidney Int 1999, 56:52-64 4,9 6. Eitner F, Cui Y, Hudkins KL, Stokes MB, Segerer S, Mack M, Lewis PL, Abraham AA, Schlöndorff D, Gallo G, Kimmel PL, Alpers CE. Chemokine receptor CCR5 and CXCR4 expression in HIV-associated kidney disease. J Am Soc Nephrol 2000, 11:856-867 7,1 7. Huber SM, Braun GS, Segerer S, Veh RW, Horster MF: Metanephrogenic mesenchyme-to-epithelium transition induces profound expression changes of ion channels. Am J Physiol 2000, 279: F65 4,4 8. Segerer S, Regele H, Mack M, Kain R, Cartron JP, Colin Y, Kerjaschki D, Schlöndorff D. The duffy antigen receptor for chemokines is up-regulated during acute renal transplant rejection and crescentic glomerulonephritis. Kidney Int 2000, 58: 1546-1556 4,9 9. Segerer S, Cui Y, Hudkins KL, Goodpaster T, Eitner F, Mack M, Schlöndorff D, Alpers CE. Expression of the chemokine monocyte chemoattractant protein-1 and its receptor chemokine receptor 2 in human crescentic glomerulonephritis. J Am Soc Nephrol 2000, 11: 2231- 2242 7,1 10. Segerer S, Cui Y, Eitner F, Goodpaster T, Hudkins KL, Mack M, Cartron JP, Colin Y, Schlöndorff D, Alpers CE. Expression of chemokines and chemokine receptors during human renal transplant rejection. Am J Kidney Dis 2001, 37: 518-531 4 11. Segerer S, Tenada S, Hudkins KL, Cui Y, Farr A, Alpers CE. Cryoglobulinemic glomerulonephritis in Thymic Stromal Lymphopoeitin Transgenic Mice. Am J Path. 2001, 159: 2355-2369 5,5 12. Hudkins KL, Le QC, Segerer S, Johnson RJ, Davis CL, Giachelli CM, Alpers CE. Osteopontin expression in cyclosporin toxicity. Kidney Int 2001, 60. 635-640 4,9 13. Anders HJ, Vielhauer V, Cohen C, Kretzler M, Segerer S, Luckow B, Weller L, Gröne HJ, Schlöndorff D. Chemokine and chemokine receptor expression during induction and resolution of immune complex glomerulonephritis. J Am Soc Nephrol 2001, 12: 919-931 7,1 14. Segerer S, Eitner F, Cui Y, Hudkins KL, Alpers CE. Cellular injury associated with renal thrombotic microangiopathy in human immunodeficiency virus- infected macaques. J Am Soc Nephrol 2002, 13: 370-378 7,1
  • 2. 15. Segerer S, Hudkins KL, Taneda S, Wen M, Cui Y, Segerer M, Farr A, Alpers CE. Oral interferon alpha treatment of mice with cryoglobulinemic glomerulonephritis. Am J Kidney Dis 2002, 39: 876- 888 4 16. Segerer S, Hughes E, Hudkins KL, Mack M, Goodpaster T, Alpers CE. Expression of the fractalkine receptor (CX3CR1) in human kidney diseases. Kidney Int 2002, 62: 488-495 4,9 17. Alpers CE, Hudkins KL, Segerer S, Sage HE, Pichler R, Couser WG, Johnson RJ, Bassuk JH. Localization of SPARC in developing, mature, and renal allograft rejection. Kidney Int 2002, 62: 2073-2086 4,9 18. Wen M, Segerer S, Dantes M, Brown P, Hudkins KL, Goodpasture T, Kirk L, LeBoeuf RC, Alpers CE. Renal Lesions in Apolipoprotein E Deficient Mice. Lab Invest. 2002, 82: 999-1006 4,5 19. Braun GS, Veh RW, Segerer S, Horster MF, Huber SM. Developmental expression and functional significance of Kir channel subunits in ureteric bud and nephron epithelia. Pflügers Archiv 2002, 445: 321-30 3,8 20. Taneda S, Hudkins KL, Cui Y, Farr AG, Alpers CE, Segerer S. Growth factor expression in a murine model of cryoglobulinemia. Kidney Int 2003, 63: 576-590 4,9 21. Lee JS, Frevert CW, Thorning DR, Segerer S, Alpers CE, Cartron JP, Colin Y, Wong VA, Martin TR, Goodman RB. Enhanced expression of the Duffy antigen during suppurative pneumonia. J Histochem Cytochem 2003, 51: 159-166 2,3 22. Segerer S, Böhmig GA, Exner M, Colin Y, Cartron JP, Kerjaschki D, Schlöndorff D, Regele H. When renal allografts turn Darc. Transplantation 2003, 75:1030-1034 3,6 23. Mühlfeld AS, Segerer S, Hudkins KL, Carling MD, Wen M, Farr AG, Ravetch JV, Alpers CE. Deletion of the Fc receptor IIb in TSLP transgenic mice aggravates membranoproliferative glomerulonephritis. Am J Kidney Dis 2003, 163: 1127-1136 4 24. Spencer MW, Muhlfeld AS, Segerer S, Hudkins KL, Kirk E, LeBoeuf RC, Alpers CE. Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice. Am J Nephrol. 2004, 24: 20-31 2,2 25. Segerer S, Banas B, Wörnle M, Schmid H, Cohen C, Kretzler M, Mack M, Kiss E, Nelson PJ, Schlöndorff D, Gröne HJ. CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis. Am J Path.2004, 164: 635-49 5,5 26. Eis V, Luckow B, Vielhauer V, Siveke JT, Linde Y, Segerer S, De Lema GP, Cohen CD, Kretzler M, Mack M, Horuk R, Murphy PM, Gao JL, Hudkins KL, Alpers CE, Grone HJ, Schlondorff D, Anders HJ. Chemokine Receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent Renal Fibrosis after Unilateral Ureteral Obstruction. J Am Soc Nephrol. 2004, 15: 337-47 7,1 27. Mühlfeld AS, S Segerer, Hudkins KL, Farr AG, Bao L, Kraus D, Holers VM, Quigg R, Alpers CE. Overexpression of complement inhibitor Crry does not prevent cryoglobulin-associated membranoproliferative glomerulonephritis. Kidney Int 2004, 65:1214-1223 4,9
  • 3. 28. Anders HJ, Belemezova E, Eis V, Segerer S, Vielhauer V, Perez de Lema G, Kretzler M, Cohen CD, Frink M, Horuk R, Hudkins KL, Alpers CE, Mampaso F, Schlöndorff D. Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL(Fas)lpr mice. J Am Soc Nephrol. 2004, 15:1504-13 7,1 29. Vielhauer V, Berning E, Eis V, Kretzler M, Segerer S, Strutz F, Horuk R, Grone HJ, Schlondorff D, Anders HJ. CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome. Kidney Int. 2004, 66: 2264-78, 2004 4,9 30. Bruhl H, Vielhauer V, Weiss M, Mack M, Schlondorff D, Segerer S: Expression of DARC, CXCR3 and CCR5 in giant cell arteritis. Rheumatology 2005, 44: 309-13 4,0 31. Ninichuk V, Gross O, Reichel C, Khandoga A, Pawar RD, Ciubar R, Segerer S, Belemezova E, Radomska E, Luckow B, de Lema GP, Murphy PM, Gao JL, Henger A, Kretzler M, Horuk R, Weber M, Krombach F, Schlondorff D, Anders HJ. Delayed C Chemokine Receptor Receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease. J Am Soc Nephrol 2005, 16: 977-985 7,1 32. Segerer S, Böhmig GA, Exner M, Kerjaschki D, Regele H, Schlöndorff D. Role of CXCR3 in cellular but not humoral renal allograft rejection Transplant Int 2005, 18: 676-680 2,3 33. Patole PS, Grone HJ, Segerer S, Ciubar R, Belemezova E, Henger A, Kretzler M, Schlondorff D, Anders HJ. Viral Double-Stranded RNA aggravates lupus nephritis through Toll-Like Receptor 3 on glomerular mesangial cells and antigen-presenting cells. J Am Soc Nephrol 2005, 16:1326-1338 7,1 34. Notohamiprodjo M, Segerer S, Huss R, Hildebrandt B, Soler D, Djafarzadeh R, Buck W, Nelson PJ, von Luettichau I. CCR10 is expressed in cutaneous T-cell lymphoma. Int J Cancer. 2005, 115:641-7 4,6 35. Gross O, Koepke ML, Beirowski B, Schulze-Lohoff E, Segerer S, Weber M. Nephroprotection by antifibrotic and anti-inflammatory effects of the vasopeptidase inhibitor AVE7688. Kidney Int 2005, 68:456-63 4,9 36. de Lema GP, Maier H, Franz TJ, Escribese M, Chilla S, Segerer S, Camarasa N, Schmid H, Banas B, Kalaydjiev S, Busch DH, Pfeffer K, Mampaso F, Schlondorff D, Luckow B. Chemokine receptor Ccr2 deficiency reduces renal disease and prolongs survival in MRL/lpr lupus- prone mice. J Am Soc Nephrol. 2005, 16:3592-3601 7,1 37. Pawar RD, Patole PS, Zecher D, Segerer S, Kretzler M, Schlondorff D, Anders HJ. Toll-Like Receptor-7 modulates immune complex glomerulonephritis. J Am Soc Nephrol. 2006, 17:141-149 7,1 38. Patole PS, Schubert S, Hildinger K, Khandoga S, Khandoga A, Segerer S, Henger A, Kretzler M, Werner M, Krombach F, Schlondorff D, Anders HJ. Toll-like receptor-4: renal cells and bone marrow cells signal for neutrophil recruitment during pyelonephritis. Kidney Int 2005, 68: 2582-2587 4,9 39. Segerer S, Hoffmann U, Rummele P, Kruger B, Pietrzyk M, Hofstadter F, Banas B, Kramer BK. Expression of the chemokine receptor CXCR3 in human renal allografts-a prospective study. Nephrol Dial Transplant. 2006, 21: 1373-1381 3,2
  • 4. 40. Hoffmann U, Banas B, Kruger B, Pietrzyk M, Obed A, Segerer S, Kammerl M, Rummele P, Riegger GA, Kramer BK. Expression of cyclooxygenase-1 and cyclooxygenase-2 in human renal allograft rejection- a prospective study. Transpl Int 2006, 19:203-212 2,3 41. Segerer S, Henger A, Schmid H, Kretzler M, Draganovici D, Brandt U, Noessner E, Nelson PJ, Kerjaschki D, Schlondorff D, Regele H. Expression of the chemokine receptor CXCR1 in human glomerular diseases Kidney Int 2006, 69: 1765-1773 4,9 42. Ninichuk V, Gross O, Segerer S, Hoffmann R, Radomska E, Buchstaller A, Huss R, Akis N, Schlondorff D, Anders HJ. Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice. Kidney Int. 2006, 70:121-129 4,9 43. Patole PS, Pawar RD, Lech M, Zecher D, Schmidt H, Segerer S, Ellwart A, Henger A, Kretzler M, Anders HJ. Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice. Nephrol Dial Transplant. 2006, 21: 3062-3073 3,2 44. von Luettichau I, Nathrath M, Burdach S, Huss R, Segerer S, Nelson PJ. Mononuclear infiltrates in osteosarcoma and chemokine receptor expression. Clin Cancer Res. 2006, 12:5253-5254 6,3 45. Hoffmann U, Banas B, Kruger B, Banas M, Bergler T, Boger C, Kammerl M, Obed A, Rummele P, Segerer S, Riegger GA, Kramer BK. SDF-1 expression is elevated in chronic human renal allograft rejection. Clin Transplant. 2006, 20: 712-718 1,9 46. Pawar RD, Patole PS, Ellwart A, Lech M, Segerer S, Schlondorff D, Anders HJ. Ligands to Nucleic Acid-Specific Toll-Like Receptors and the onset of Lupus nephritis J Am Soc Nephrol. 2006, 17:3365-3373 7,1 47. Heller F, Cohen CD, Lindenmeyer MT, Brandt U, Draganovici D, Fischereder M, Matthias Kretzler, Anders HJ, Sitter T, Kerjaschki D, Regele H, Schlöndorff D, Segerer S. The contribution of B cells to renal interstitial inflammation. Am J Pathol. 2007, 170:457-468 5,5 48. Koepke ML, Weber M, Schulze-Lohoff E, Beirowski B, Segerer S, Gross O. Nephroprotective effect of the HMG-CoA-reductase inhibitor cerivastatin in a mouse model of progressive renal fibrosis in Alport syndrome. Nephrol Dial Transplant. 2007, 22: 1720-1729 3,2 49. Mayer V, Hudkins KL, Heller F, Schmid H, Kretzler M, Brandt U, Anders HJ, Regele H, Nelson PJ, Alpers CE, Schlöndorff D, Segerer S. Expression of the chemokine receptor CCR1 in human renal allografts. Nephrol Dial Transplant. 2007, 22:1720-1729 3,2 50. Pawar RD, Ramanjaneyulu A, Kulkarni OP, Lech M, Segerer S, Anders HJ. Inhibition of Toll-like receptor (TLR)-7 or TLR7 plus TLR9 prevents glomerulonephritis and lung injury in experimental lupus. J Am Soc Nephrol. 2007, 18:1721-1731 7,1 51. Segerer S, Djafarzadeh R, Gröne HJ, Weingart C, Kerjaschki D, Weber C, Kungl AJ, Regele H, Proudfoot AEI, Nelson PJ. Selective binding and presentation of CCL5 by discrete tissue microenvironments during renal inflammation. J Am Soc Nephrol. 2007, 18:1835-1844 7,1 52. Patole PS, Pawar RD, Lichtnekert J, Leck M, Kulkarni O, Ramanjaneyulu A, Segerer S, Anders HJ. Coactivation of Toll-like receptor-3 and -7 in immune complex glomerulonephritis. J Autoimmun. 2007, 29:52-59 3,4
  • 5. 53. Ninichuk V, Khandoga AG, Segerer S, Loetscher P, Schlapbach A, Revesz L, Feifel R, Khandoga A, Krombach F, Nelson PJ, Schlondorff D, Anders HJ. The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice. Am J Pathol. 2007, 170:1267-76 5,5 54. Derfuss T, Segerer S, Herberger S, Sinicina I, Hufner K, Ebelt K, Knaus HG, Steiner I, Meinl E, Dornmair K, Arbusow V, Strupp M, Brandt T, Theil D. Presence of HSV-1 Immediate Early Genes and Clonally Expanded T-cells with a Memory Effector Phenotype in Human Trigeminal Ganglia. Brain Pathol. 2007, 17:389-98 3,7 55. von Luettichau I, Segerer S, Wechselberger A, Notohamiprodjo M, Nathrath M, Kremer M, Henger A, Djafarzadeh R, Burdach S, Huss R, Nelson PJ. A complex pattern of chemokine receptor expression is seen in osteosarcoma. BMC Cancer. 2008, 8: 23 2,7 56. Kulkarni O, Pawar RD, Purschke W, Eulberg D, Selve N, Buchner K, Ninichuk V, Segerer S, Vielhauer V, Klussmann S, Anders HJ. Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice. J Am Soc Nephrol. 2007, 18: 2350-2358 7,1 57. Ninichuk V, Clauss S, Kulkarni O, Schmid H, Segerer S, Radomska E, Eulberg D, Buchner K, Selve N, Klussmann S, Anders HJ. Late Onset of Ccl2 Blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice. Am J Pathol. 2008, 172: 628-37 5,5 58. Segerer S, Heller F, Lindenmeyer MT, Schmid H, Cohen CD, Draganovici D, Mandelbaum J, Nelson PJ, Gröne HJ, Gröne EF, Figel AM, Nössner E, Schlöndorff D. Compartment specific expression of dendritic cell markers in human glomerulonephritis. Kidney Int. 2008, 74:37-46 4,9 59. Lehmann I, Fischereder M, Böhmig GA, Regele H, Exner M, Raith M, Weiss N, Segerer S. The source matters: No impact of the CCL2/MCP-1-2518G polymorphism of the donor on renal allograft outcome during the first year of transplantation. Transplant Proc. 2008, 40:3359-3361 1,0 60. Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham G, Segerer S, Nibbs R, Rot A. Duffy antigen/receptor for chemokines transports chemokines and supports their pro-migratory activity in vitro and in vivo. Nature Immunol 2009, 10:101-108 26 61. Clauss S, Gross O, Kulkarni O, Avila-Ferrufino A, Radomska E, Segerer S, Eulberg D, Klussmann S, Anders HJ. Ccl2/Mcp-1 blockade reduces glomerular and interstitial macrophages but does not ameliorate renal pathology in collagen4A3-deficient mice with autosomal recessive Alport nephropathy. J Pathol. 2008, 218: 40-47 5,8 62. Lichtnekert J, Vielhauer V, Zecher D, Kulkarni OP, Clauss S, Segerer S, Hornung V, Mayadas TN, Beutler B, Akira S, Anders HJ. Dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif in immune complex glomerulonephritis. Am J Physiol Renal Physiol. 2009, 296: F867-874 4,5 63. Pawar RD, Castrezana-Lopez L, Allam R, Kulkarni OP, Segerer S, Radomska E, Meyer TN, Schwesinger CM, Akis N, Gröne HJ, Anders HJ. Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier. Immunology. 200, 128(1 Suppl):e206-221 3,4
  • 6. 64. Kulkarni O, Eulberg D, Selve N, Zöllner S, Allam R, Pawar RD, Pfeiffer S, Segerer S, Klussmann S, Anders HJ. Anti-Ccl2 Spiegelmer permits 75% dose reduction of cyclophosphamide to control diffuse proliferative lupus nephritis and pneumonitis in MRL-Fas(lpr) mice. J Pharmacol Exp Ther. 2009, 328: 371-377 4,0 65. Vielhauer V, A Ramanjaneyulu, MT Lindenmeyer, CD Cohen, Draganovici D, Mandelbaum J, Eltrich N, Nelson PJ, Anders HJ, Pruenster M, Rot A, Schlöndorff D, Segerer S. Efficient renal recruitment of macrophages and T cells in mice lacking the Duffy antigen/receptor for chemokines. Am J Path 2009, 175:119-131 5,9 66. Segerer S, Johnson Z, Rek A, Baltus T, von Hundelshausen P, Kungl AJ, Proudfoot AEI, Weber C, Nelson PJ. The basic residue cluster 55 KKWVR59 in CCL5 is required for in vivo biologic function Mol Immunol 2009, 46: 2533-2538 3 67. Lech M, Avila-Ferrufino A, Allam R, Segerer S, Khandoga A, Krombach F, Garlanda C, Mantovani A, Anders HJ. Resident dendritic cells prevent postischemic acute renal failure by help of single immunoglobulin interleukin-1 receptor-related protein. J Immunol 2009, 183:4109-4118 6 68. Sayyed SG, Hägele H, Kulkarni OP, Endlich K, Segerer S, Eulberg D, Klussmann S, Anders HJ. Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes. Diabetologia. 2009, 52:2445-2454 6,4 69. Geleff S, Draganovici D, Jaksch P, Segerer S. The role of chemokine receptors in acute lung allograft rejection. Eur Resp J, 35:167-175; 2010 5,5 70. Sostak P, Padovan CS, Eigenbrod S, Roeber S, Segerer S, Schankin C, Siegert S, Saam T, Theil D, Kolb HJ, Kretzschmar H, Straube A. Cerebral angiitis in four patients with chronic GVHD. Bone Marrow Transplant. 2010, 45: 1181-1188 3,4 71. Neusser MA, Lindenmeyer MT, Moll AG, Segerer S, Edenhofer I, Sen K, Stiehl DP, Kretzler M, Gröne HJ, Schlöndorff D, Cohen CD. Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Am J Pathol. 2010, 176:594-607 5,9 72. Jedlicka J, Soleiman A, Draganovici D, Mandelbaum J, Ziegler U, Regele H, Wüthrich RP, Gross O, Anders HJ, Segerer S. Interstitial inflammation in Alport syndrome. Hum Pathol. 2010, 41: 582-593 3,3 73. Neusser MA, Kraus AK, Regele H, Cohen CD, Fehr T, Kerjaschki D, Wüthrich RP, Penfold ME, Schall T, Segerer S. The chemokine receptor CXCR7 is expressed on lymphatic endothelial cells during renal allograft rejection. Kidney Int. 2010, 77: 801-808 6,4 74. Bergamin B, Senn O, Corsenca A, Dutkowski P, Weber M, Wüthrich RP, Segerer S, Pechula Thut M. Finding the right position: a three year, single-center experience with the “self-locating” catheter. Perit Dial Int. 2010, 30: 519-23 1,9 75. Gross O, Girgert R, Beirowki B, Kretzler M, Kang HG, Kruegel J, Miosge N, Busse AC, Segerer S, Vogel WF, Müller GA, Weber M. Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease Matrix Biol 2010, 29: 346-56 3,6 76. Hoffmann U, Bergler T, Segerer S, Rümmele P, Krüger B, Banas MC, Reinhold S, Banas B, Krämer BK. Impact of chemokine receptor CX3CR1 in human renal allograft rejection. Transpl Immunol. 2010, 23: 204-8 2,4
  • 7. 77. Lin M, Yin N, Murphy B, Medof ME, Segerer S, Heeger PS, Schröppel B: Immune cell-derived c3 is required for autoimmune diabetes induced by multiple low doses of streptozotocin. Diabetes. 2010, 59: 2247-52 8,5 78. Tian Y, Chen J, Gaspert A, Segerer S, Clavien PA, Wüthrich RP, Fehr T. Kidney Transplantation in Mice Using Left and Right Kidney Grafts. J Surg Res. 2010, 163: e91-7 2,2 79. Braun N, Alscher DM, Fritz P, Edenhofer I, Kimmel M, Gaspert A, Reimold F, Bode-Lesniewska B, Ziegler U, Biegger D, Wüthrich RP, Segerer S. Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis. Nephrol Dial Transplant 2011, 26:1033-41 3,3 80. Neusser MA, Lindenmeyer MT, Edenhofer I, Gaiser S., Kretzler M, Regele H, Segerer S, Cohen CD. Intrarenal production of B cell survival factors in human lupus nephritis Mod. Pathol 2011, 24: 98-107 4,4 81. Lin M, Murphy B, Medof ME, Segerer S, Heeger PS, Schröppel B. Response to Comment on: Lin et al. Immune Cell-Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin. Diabetes. 2011, 59:2247-2252 8,5 82. Starke A, Lindenmeyer MT, Segerer S, Neusser MA, Rüsi B, Schmid DM, Cohen CD, Wüthrich RP, Fehr T, Waeckerle-Men Y. Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses. Kidney Int. 2010, 78: 38-47 6,4 83. Welsh-Bacic D, Lindenmeyer M, Cohen CD, Draganovici D, Mandelbaum J, Edenhofer I, Ziegler U, Regele H, Wüthrich RP, Segerer S: Expression of the chemokine receptor CCR6 in human renal inflammation. Nephrol Dial Transplant. 2011, 26: 1211-20 3,3 84. Figel AM, Brech D, Prinz PU, Lettenmeyer UK,Hosse J, Turqueti- Neves A, Mysliwietz J, Anz D, Rieth N, Muenchmeier N, Buchner A, Porubsky S, Siegert SI, Segerer S, Nelson PJ, Noessner E: Human renal cell carcinoma induces a dendritic cell subset that uses T-cell crosstalk for tumor-permissive milieu alterations. Am J Pathol 2011, 179: 436-451 5,9 85. Raina S, Honer M, Krämer SD, Liu Y, Wang X, Segerer S, Wüthrich RP, Serra AL. Anti-VEGF antibody treatment accelerates polycystic kidney disease. Am J Physiol Renal Physiol. 2011, 301: F773- 83 3,8 86. Cippa PE, Kraus AK, Edenhofer I, Segerer S, Chen J, Hausmann M, Liu Y, Guimezanes A, Bardwell PD, Wüthrich RP, Fehr T: The BH3- mimetic ABT-737 inhibits allogeneic immune responses. Transplant Int. 2011, 24: 722–732 3,2 87. Sen K, Lindenmeyer MT, Gaspert A, Eichinger F, Neusser MA, Kretzler M, Segerer S, Cohen CD. Periostin is induced in glomerular injury and expressed de novo in interstitial renal fibrosis. Am J Pathol. 2011, 179: 1756-67 5,2 88. Seleznik GM, Reding T, Romrig F, Saito Y, Mildner A, Segerer S, Sun LK, Regenass S, Lech M, Anders HJ, McHugh D, Kumagi T, Hiasa Y, Lackner C, Haybaeck J, Angst E, Perren A, Balmer ML, Slack E, MacPherson A, Manz M, Weber A, Browning J, Arkan MC, Rülicke T, Aguzzi A, Prinz M, Graf R, Heikenwalder M: A Lymphotoxin-driven, IL17- independent pathway to autoimmune pancreatitis and systemic autoimmunity Gastroenterology. 2012, 143: 1361-74 12,0
  • 8. 89. Berthier CC, Gonzalez-Rivera T, Bethunaickan R, Nair V, Ramanujam M, Zhang W, Bottinger EP, Segerer S, Davidson A, Kretzler M. Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis. J Immunol. 2012, 189: 988-1001 5.7 90. Braun N, Fritz P, Ulmer C, Latus J, Kimmel M, Biegger D, Ott G, Reimold F, Thon KP, Dippon J, Segerer S, Alscher DM. Histological criteria for encapsulating peritoneal sclerosis - a standardized approach. PLOS ONE. 2012, 7: e48647 4,1 91. Braun N, Alscher MD, Fritz P, Latus J, Edenhofer I, Reimold F, Alper SL, Kimmel M, Biegger D, Lindenmeyer M, Cohen CD, Wüthrich RP, Segerer S: The Spectrum of Podoplanin Expression in Encapsulating Peritoneal Sclerosis. PLOS ONE. 2012, 7: e48647 4.1 92. Latus J, Ulmer C, Fritz P, Rettenmaier B, Biegger D, Lang T, Ott G, Kimmel M, Steurer W, Alscher MD, Segerer S, Braun N. Phenotypes of Encapsulating Peritoneal Sclerosis –Macroscopical Appearance, Histological Findings and Outcome. Perit Dial Int 2013, 33: 495-502 2.1 93. Cippà PE, Kamarashev J, Chen J, Kraus AK, Segerer S, Feldmeyer L, Fehr T. Synergistic Bcl-2 inhibition by ABT-737 and cyclosporine A. Apoptosis. 2013, 18: 315-23 4.8 94. Reimold FR, Braun N, Zsengellér ZK, Stillman IE, Karumanchi SA, Toka HR, Latus J, Fritz P, Biegger D, Segerer S, Alscher MD, Bhasin MK, Alper SL: Transcriptional Patterns in Peritoneal Tissue of Encapsulating Peritoneal Sclerosis, a Complication of Chronic Peritoneal Dialysis PLOS ONE. 2013, 8: e56389 4.1 95. Braun N, Sen K, Alscher MD, Fritz P, Kimmel M, Morelle J, Goffin E, Jörres A, Wüthrich RP, Cohen CD, Segerer S. Periostin- a matricellular protein involved in peritoneal injury during peritoneal dialysis Perit Dial Int 2013, 33: 515-28 2.1 96. Kraus AK, Cippá PE, Gaspert A, Chen J, Edenhofer I, Wüthrich RP, Lindenmeyer M, Segerer S, Fehr T. Absence of donor CD40 protects renal allograft epithelium and preserves renal function. Transpl Int. 2013, 26: 535-44 3.2 97. Wang X, Zhang S, Yang L, Spichtig D, Kapoor S, Koepsell H, Mohebbi N, Segerer S, Serra AL, Devuyst O, Mei C, Wüthrich RP: Glycosuria induction via phlorizin-mediated SGLT inhibition prevents disease progression in Han:SPRD rats with polycystic kidney disease. Kidney Int. 2013, 84: 962-8 7.9 98. Latus J, Goffin E, Schroeder JA, Fritz P, Ott G, Ulmer C, Steurer W, Kimmel M, Biegger D, Segerer S, Alscher MD, Braun N. Gadolinium deposits and delayed peritoneal clearance in patients on peritoneal dialysis and in patients with encapsulating peritoneal sclerosis Perit Dial Int. 2014, 34: 561-565 2.1 99. D. Spichtig, H. Zhang, N. Mohebbi, I. Pavik, K. Petzold, G. Stange, L Saleh, I. Edenhofer, S. Segerer, O. Devuyst, J. Biber, P. Jaeger, AL. Serra, CA. Wagner: Renal Expression of FGF23 and Peripheral Resistance to elevated FGF23 in rodent models of Polycystic Kidney Disease. Kidney Int 2014, 85: 1340-50 7.9
  • 9. 100. Seeger H, Braun N, Latus J, Alscher MD, Fritz P, Edenhofer I, Biegge D, Lindenmeier M, Wüthrich RP, Segerer S: Platelet-derived growth factor receptor β (PDGFRβ) expression in human peritoneum. Nephron Clin Pract. 2014; 128: 178-84 1.7 101. Latus J, Habib SM, Kitterer D, Korte MR, Ulmer C, Fritz P, Davies S, Lambie M, Alscher MD, Betjes MG, Segerer S, Braun N; on behalf of the European EPS study group. Histological and clinical findings in patients with post-transplantation and classical encapsulating peritoneal sclerosis: a European multicenter study. PLoS One. 2014, 9: e106511 3.5 102. Latus J, Schwab M, Tacconelli E, Pieper FM, Wegener D, Rettenmaier B, Schwab A, Hoffmann L, Dippon J, Müller S, Fritz P, Zakim D, Segerer S, Kitterer D, Kimmel M, Gußmann K, Priwitzer M, Mezger B, Walter-Frank B, Corea A, Wiedenmann A, Brockmann S, Pöhlmann C, Alscher MD, Braun N. Defining risk for severe acute kidney injury in 456 patients with Hantavirus induced Nephropathia Epidemica. Nephrol, Dial, Transplant 2015; 30: 245-51 3.5 103. Latus J, Schwab M, Tacconelli E, Pieper FM, Wegener D, Rettenmaier B, Schwab A, Hoffmann L, Dippon J, Müller S, Fritz P, Zakim D, Segerer S, Kitterer D, Priwitzer M, Mezger B, Walter-Frank B, Corea A, Wiedenmann A, Brockmann S, Pöhlmann C, Alscher MD, Braun N. Clinical course and long-term outcome in 456 patients with Hantavirus- induced Nephropathia epidemica, Germany, 2001-2012. Emerg Infect Dis. 2015; 21: 76-83 7.3 104. Latus J, Kitterer D, Segerer S, Artunc F, Alscher MD, Braun N. Severe thrombocytopenia in hantavirus-induced nephropathia epidemica. Infection. Infection. 2015; 43: 83-7 2.9 105. Latus J, Kitterer D, Dippon J, Müller S, Artunc F, Segerer S, Alscher MD, Braun N. Polyuria in hantavirus infection reflects disease severity and is associated with prolonged hospital stay – a systematic analysis of 335 patients from Southern Germany. Nephron Exp Nephrol. 2015 [epub ahead of print] 1.7 106. Thalhammer C, Segerer S, Augustoni M, Jacomella V, Clemens RK, Wüthrich RP, Amann-Vesti BR, Husmann M. Acute effects of haemodialysis on central venous and arterial pressure characteristics. Nephrology (Carlton). 2015; 20: 91-5 1.9 107. Kapoor S, Rodriguez D, Riwanto M, Edenhofer I, Segerer S, Mitchell K, Wüthrich RP. Effect of Sodium-Glucose Cotransport Inhibition on Polycystic Kidney Disease Progression in PCK Rats. PLoS One. 2015;10(4): e0125603 3.5 108. Latus J, Kitterer D, Segerer S, Artunc F, Alscher MD, Braun N. Determination of procalcitonin levels in patients with nephropathia epidemica - a useful tool or an unnecessary diagnostic procedure? Kidney Blood Press Res. 2015; 40: 22-30 2.1 109. Seleznik G, Seeger H, Bauer J, Fu K, Czerkowicz J, Papandile A, Poreci U, Rabah D, Ranger A, Cohen CD, Lindenmeyer M, Chen J, Edenhofer I, Anders HJ, Lech M, Wüthrich RP, Ruddle NH, Moeller MJ, Kozakowski N, Regele H, Browning JL, Heikenwalder M, Segerer S. The lymphotoxin β receptor is a potential therapeutic target in renal inflammation. Kidney Int. 2015 [epub ahead of print] 8.5
  • 10. 110. Kitterer D, Latus J, Ulmer C, Fritz P, Biegger D, Ott G, Alscher MD, Witowski J, Kawka E, Joerres A, Seeger H, Segerer S, Braun N. Activation of Nuclear Factor of Activated T Cells 5 in the peritoneal membrane of uremic patients. Am J Physiol Renal Physiol. 2015, 308: F1247-58 3.2 111. Kitterer D, Gürzing K, Segerer S, Alscher MD, Amann K, Braun N, Latus J. Diagnostic impact of percutaneous renal biopsy. Clin Nephrol. 2015, 84: 311-22 1.1 112. Kitterer D, Segerer S, Steurer W, Dippon J, Geissler A, Ulmer C, Braun N, Alscher MD, Latus J. C-reactive protein levels in combination with abdominal CT scans is a useful tool to predict the macroscopic appearance in late-stage EPS patients prior to surgery. Int J Nephrol Renovasc Dis. 2015, 8: 83-90 113. Kitterer D, Artunc F, Segerer S, Alscher MD, Braun N, Latus J. Evaluation of lipase levels in patients with nephropathia epidemica--no evidence for acute pancreatitis. BMC Infect Dis. 2015, 15: 286 2.6 114. Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S, Cohen CD, Neuhauss SC, Loffing J. The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney Int. 2016 [epub ahead of print] 8.5 115. Kitterer D, Segerer S, Alscher MD, Braun N, Latus J. Puumala Hantavirus-Induced Hemorrhagic Fever with Renal Syndrome must be considered across the borders of nephrology to avoid unnecessary diagnostic procedures. PLoS One. 2015, 10: e0144622. 3.2 116. Prange JA, Bieri M, Segerer S, Burger C, Kaech A, Moritz W, Devuyst O. Human proximal tubule cells form functional microtissues. Pflugers Arch. 2015 [Epub ahead of print] 4.1 117. Rodriguez D, Kapoor S, Edenhofer I, Segerer S, Riwanto M, Kipar A, Yang M, Mei C, Wüthrich RP. Inhibition of Sodium- GlucoseCotransporter 2 with Dapagliflozin in Han: SPRD Rats with Polycystic Kidney Disease. Kidney Blood Press Res. 2015;40: 638-47 2.1 118. Riwanto M, Kapoor S, Rodriguez D, Edenhofer I, Segerer S, Wüthrich RP. Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease. PLoS One. 2016 11: e0146654 3.2 119. Kraus AK, Chen J, Edenhofer I, Ravens I, Gaspert A, Cippà PE, Mueller S, Wuthrich RP, Segerer S, Bernhardt G, Fehr T. The Role of T Cell Costimulation via DNAM-1 in Kidney Transplantation. PLoS One. 2016, 11: e0147951 3.2 Fallbeschreibungen 120. Meister P, Segerer W, Segerer S, Auer K. Interstitielle Nephritis mit akutem Nierenversagen bei Ascaris-lumbricoides-Infektion. Pathologe 1995, 16: 434-438 0,3 121. Segerer S, Feth M, Segerer W. Fieber, Diarrhoe und akutes polyurisches Nieren-versagen-Hantavirusinfektion, Nephropathia epidemica. Spektrum der Nephrologie 1997, 2 122. Segerer S, Dietz-Laukemann P, Schattenkirchner M. RS3PE- Syndrom. Z Rheumatologie 1999, 58: 35-38 0,7 123. Segerer S, Mühlhöfer A, Gross M, Kellner W, Spengel FA, Pfeifer J. Angina abdominalis- Duplexsonographische Diagnose und perkutane Revaskularisierung VASA 200, 29, 141-145 0,5 124. Schröppel B, Segerer S, Keuneke C, Cohen CD, Schlöndorff D. Hyponatremic encephalopathy after preparation for colonoscopy. 5,9
  • 11. Gastrointestinal Endoscopy 2001, 53: 527-529 125. Schwegler I, Segerer S. A painful fistula. Circulation. 2011, 123: 2606 14.6 126. Schleich A, Gerber L, Wüthrich RP, Segerer S. Peri-renal Hematoma After Intraperitoneal Cefazolin Treatment for Peritonitis. Perit Dial Int. 2011, 31: 505-507 1.9 127. Kocher C, Segerer S, Schleich A, Caduff R, Wyler LG, Müller V, Beck B, Blum J, Kamarachev J, Mueller NJ. Skin lesions, malaise, and heart failure in a renal transplant recipient. Transpl Infect Dis. 2012, 14: 391-7 2.0 128. Cippà PE, Auinger K, Wüthrich RP, Segerer S. An infectious cause of acute kidney injury with low serum potassium. BMJ Case Rep. 2016 [epub ahead of print] Übersichtsarbeiten 129. Floege J, S Segerer, J Schäffer, KM Koch. Langzeitbetreuung von Dialysepatienten II. 2-Mikroglobulin assoziierte Amyloidose und erworbene zystische Nierenerkrankung. Internist 1999, 40: 64-69 0,3 130. Schlöndorff D, S Segerer. Pathogenesis of glomerulonephritis, a perspective from the last 30 years. J Nephrology 1999, 12 suppl. 2, S131-141 1,1 131. Segerer S, PJ Nelson, D Schlöndorff. Chemokines, chemokine receptors, and renal disease: from basic science to pathophysiologic and therapeutic studies. J Am Soc Nephrol 2000, 11: 152-176 7,1 132. Segerer S. The Role of chemokines and chemokine receptors in progressive renal diseases. Am J Kidney Dis. 2003, 41(S1): S15-S18 4 133. Segerer S, Alpers CE. Chemokines and chemokine receptors in renal pathology. Curr Opin Nephrol Hypertens. 2003, 12: 243-249 4,1 134. Segerer S, Nelson PJ. Chemokines in renal diseases. ScientificWorldJournal 2005, 5: 835-844 135. Segerer S, Schlöndorff D. Role of chemokines for the localization of leukocytes subsets in the kidney. Semin Nephrol 2007, 27: 260-74 1,9 136. Segerer S, Schlöndorff D. B cells and tertiary lymphoid organs in renal inflammation. Kidney Int 2008, 73: 533-7 4,9 137. Gross O, Borza DB, Anders HJ, Licht C, Weber M, Segerer S, Torra R, Gubler MC, Heidet L, Harvey S, Cosgrove D, Lees G, Kashtan C, Gregory M, Savige J, Ding J, Thorner P, Abrahamson DR, Antignac C, Tryggvason K, Hudson B, Miner JH. Stem cell therapy for Alport syndrome: the hope beyond the hype. Nephrol Dial Transplant. 2009, 24: 731-4 3,2 138. Segerer S, Jedlicka J, Wüthrich R. Atypical chemokine receptors in renal inflammation. Nephron Exp Nephrol 2010, 115: e89-e95 2,0 139. Wüthrich RP, Segerer S. Mechanismen der renalen Salzregulation und ihre medikamentöse Beeinflussung. Cardiovasc 5: 6- 10, 2009 140. Lindenmeyer M, Noessner E, Nelson PJ, Segerer S. Dendritic cells in experimental renal inflammation - part I. Nephron Exp Nephrol. 2011, 119: e83-90 2.7 141. Noessner E, Lindenmeyer M, Nelson PJ, Segerer S. Dendritic Cells in Human Renal Inflammation - Part II. Nephron Exp Nephrol. 2011 119: e91-8 2.7 142. Seeger H, Bonani M, Segerer S. The role of lymphatics in renal inflammation. Neprol Dial Transplant. 2012 27:2634-41 3.6 143. Thalhammer C, Pfammatter T, Segerer S. Vascular accesses for hemodialysis - an Update. Vascular accesses for hemodialysis - an 0.9
  • 12. update. Vasa. 2013, 42: 252-6 144. Thalhammer C, Segerer S. Hemodialysis vascular access. Dtsch Med Wochenschr 2014, 139: 1562-4 0.7 145. Seeger H, Segerer S. The role of lymphatic vessels in renal injury. J Clin Cell Immunol 2014, 5: 255 146. Seeger H, Kitterer D, Latus J, Alscher MD, Braun N, Segerer S. The potential role of NFAT5 and osmolarity in peritoneal injury. Biomed Res Int. 2015: 578453. Buchkapitel: 147. Nelson PJ, Segerer S, Schlöndorff D. Chemoattractants and chemokines in renal disease. In: Immunologic renal diseases. edn 2. Edited by Neilson EG, Couser WG. Lippincott Williams & Wilkins: 2001, 521-550 148. Segerer S, F. Strutz, M. Kretzler, D. Schlöndorff. Tissue injury in renal diseases In: Diseases of the Kidney and Urinary Tract. Edited by Schrier RW, 2006 149. Mühlfeld A, Segerer S, Alpers C. HIV associated thrombotic microangiopathy Mühlfeld A, Segerer S, Alpers C. HIV associated thrombotic microangiopathy. In: AIDS and Heart Disease. Edited by Watson RR. Marcel Dekker: 2004, 71-83 150. Nelson PJ, Segerer S, Schlondorff D: Chemokines in Transplantation Biology. In: The Receptors: The Chemokine Receptors Edited by: J. K. Harrison, N. W. Lukacs: 2007 Zürich, den 15.03.2016 Stephan Segerer