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Personal Details
French national, 34 years old Address: 11 Grigg Grove, Birmingham B31 5HR
Telephone: +44 (0) 121 477 2608
In partnership, one child
Email: cauchyp@bham.ac.uk
Scientific Background
2011-present: Postdoctoral Research Fellow in molecular haematopoiesis and oncology,
Prof. Bonifer’s group, Cancer Sciences, University of Birmingham
2010: PhD Bioinformatics, Biochemistry, Genomics, Université Aix-Marseille. Title: "Role and
transcriptional context of the transcription factor ETS1 during the DN/DP transition in αβ
thymocyte differentiation", PhD supervised by Dr Andrau and Dr Imbert, CIML CNRS
UMR6102/INSERM U631 and TAGC INSERM U928, Marseille, France
2006: MRes Bioinformatics, University of Glasgow. Research project: "Motif discovery in
Interleukin 2 regulated genes", project work supervised by Dr Imbert, INSERM U599,
Marseille, France
2004: MSc Biology, Université de La Rochelle, France
2000: Undergraduate Microbiology, Imperial College London, London, UK
1997: French Scientific Baccalaureate, Specialisation in Mathematics, “Mention Assez Bien”
Expertise
Wet lab:
Chromatin immunoprecipitation (ChIP), ChIP-Seq, DNAseI-Seq, MNase-Seq, PCR, RT-qPCR,
ChIP-chip and expression microarrays, cell culture, western blot, MACS sorting, FACS, animal
experimentation, patient sample processing.
Bioinformatics:
ChIP-Seq, DNAse-Seq, MNase-Seq & RNA-Seq analysis, programming in Java, Perl, R, PHP
ChIP-chip, expression & m5C microarray analysis, digital footprinting, motif discovery,
sequence analysis, functional and comparative genomics; databases: MySQL, Oracle.
Scientific Communication
Published peer-reviewed publications
Imperato MR, Cauchy P, Obier N, Cockerill PN, Bonifer C. The RUNX1- PU.1 axis in the control of
hematopoiesis. Int J Hematol 2015 Mar 8. DOI: 10.1007/s12185-015-1762-8 [Epub ahead of print]
Zacarias-Cabeza J, Behlocine M, Vanhille L, Cauchy P, Koch F, Fenouil R, Bergon A, Gut A, Gut I,
Eick D, Imbert J, Ferrier P, Andrau JC, Spicuglia S. Transcription dependent generation of a
specialized chromatin structure at the Tcrβ locus. J Immunol 2015 Mar 2. pii: 1400789. [Epub
ahead of print]
Pierre Cauchy, Molecular and Computational Biologist
Obier N, Lin Q, Cauchy P, Hornich V, Zenke M, Becker M, Müller A. Polycomb protein EED is
required for silencing of pluripotency genes upon ESC differentiation. Stem Cell Rev. 2015
Feb;11(1):50-61
Kreher S, Cauchy P, Bonifer C, Mathas S. Cytokine and proinflammatory gene expression in
classical Hodgkin lymphoma: its more than NF- κB! Cytokine. 2015 Jan 10. pii: S1043-
4666(14)00626-7
Kreher S, Bouhlel A, Cauchy P, Lamprecht B, Li S, Hummel F, Köchert K, Anagnostopoulos I,
Hummel M, Hiscott J, Wenzel SS, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R,
Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S. Mapping of transcription
factor motifs in active chromatin identifies key regulators in human lymphoma. Proc Natl Acad
Sci. 2014 Oct 6. pii: 201406985
Ptasinska A, Assi SA, Martinez-Soria N, Piper J, Cauchy P, Imperato MR, Pickin A, James SR,
Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O,
Bonifer C. Identification of a dynamic core transcriptional network in t(8;21) AML regulating
differentiation block and self-renewal. Cell Rep. 2014 Sep 17. pii: S2211-1247(14)00687-1
Drummond MW, Pocock C, Boissinot M, Mills J, Brown J, Cauchy P, Cross NC, Hartley S, Kell J,
Szubert A, Cockerill PN, Bowen DT. A multi-centre phase 2 study of azacitidine in chronic
myelomonocytic leukaemia. Leukemia. 2014 Jul;28(7):1570-2
Piper J, Elze M, Cauchy P, Cockerill PN, Bonifer C, Ott S. Wellington: A novel method for the
accurate identification of digital genomic footprints from DNase-seq data. Nucleic Acids Res.
2013 Nov;41(21):e201
Fenouil R*, Cauchy P*, Koch F*, Descostes N, Cabeza JZ, Innocenti C, Ferrier P, Spicuglia S, Gut M,
Gut I, Andrau JC. CpG islands and GC content dictate nucleosome depletion in a transcription-
independent manner at mammalian promoters. Genome Res. 2012 Dec;22(12):2399-408
Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M,
McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR,
Heidenreich O, Bonifer C. Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide
changes in chromatin structure and transcription factor binding. Leukemia. 2012
Aug;26(8):1829-41
Koch F, Fenouil R, Gut M, Cauchy P, Albert TK, Zacarias-Cabeza J, Spicuglia S, Heidemann M,
Hintermair C, Eick D, Gut I, Ferrier P, Andrau JC. Transcription Initiation Platforms and GTF
recruitment at tissue specific enhancers and promoters. Nat Struct Mol Biol. 2011 Jul
17;18(8):956-63
Cauchy P, Benoukraf T, Ferrier P. Processing ChIP-chip Data: From the Scanner to the Browser.
Methods Mol Biol. 2011 719:251-68
Benoukraf T*, Cauchy P*, Fenouil R*, Jeanniard A, Koch F, Jaeger S, Thieffry D, Imbert J, Andrau JC,
Spicuglia S, Ferrier P. CoCAS: a ChIP-on-Chip Analysis Suite. Bioinformatics. 2009 Apr 1;
25(7):954-5
*co-first author
Manuscripts in revision
Klein-Hessling S, Rudolf R, Muhammad K, Knobeloch KP, Maqbool MA, Cauchy P, Andrau JC, Avots
A, Talora C, Ellenrieder V, Screpanti I, Serfling E, Patra AK. NFATc1 activity is critical for T cell
development and to prevent both T cell lymphopenia and leukemia. Nat Commun
Cauchy P, James S, Ptasinska A, Zacarias-Cabeza J, Imperato MR, Assi SA, Piper J, Canestraro M,
Hoogenkamp M, Raghavan M, Loke C, Akiki S, Clokie S, Richards SR, Westhead D, Griffiths MJ, Ott
S, Bonifer C, Cockerill PN. Chronic growth factor signaling in Acute Myeloid Leukemia is
connected to a specific epigenetic signature. Cell Rep
Cauchy P, Zacarias-Cabeza J, Vanhille L, Koch F, Fenouil R, Gut M, Gut I, Maqbool MA, Griffon A,
Imbert J, Ferrier P, Spicuglia S, Andrau JC. Dynamic recruitment of Ets1 to both nucleosome -
occupied and -depleted enhancer regions mediates a transcriptional program switch during
early T-cell differentiation. Nucleic Acids Res
Manuscripts under review
Piper J, Assi SA, Cauchy P, Ladroue C, Cockerill PN, Bonifer C, Ott, S. Differential DNase-seq
footprinting identifies cell-type determining transcription factors. BMC Genomics
Manuscripts submitted
Bevington S, Cauchy P, Piper J, Bertrand E, Lalli N, Ott S, Bonifer C, Cockerill PN. Defining the
molecular mechanisms underlying the epigenetic basis of immunological memory in T
cells.Immunity
Benoukraf T, Cauchy P, Bardet A, Le P, Jaeger S, Imbert J, Thieffry D, Graziani S, Ferrier P. A
data‐morphing approach for the identification of transcription factor binding sites exploiting
high‐throughput sequencing data. BMC Bioinformatics
Manuscripts in preparation
Benoukraf T, Spinelli L, Jaeger S, Cauchy P, Tenen DG, Imbert J, Thieffry D, Ferrier P, Van Helden J.
Peak-footprints: A phylogenetic footprinting pipeline for identifying transcription factor binding
targets from high-throughput chromatin immunoprecipitation (ChIP) profiles.
Goode DK, Obier N, Vijayabaskar MS, Lichtinger M, Hannah, R, Lie-A-Ling M, Lilly AJ, Florowska M,
Batta K, Challinor M, Wallace K, Assi SA, Cauchy P, Gilmour J, Hoogenkamp M, Westhead DR,
Lacaud G, Kouskoff V, Göttgens B, Bonifer C. Comprehensive Genome-Scale Analysis Of A
Complete Developmental Pathway.
Obier N, Lichtinger M, Cauchy P, Assi SA, Vijayabaskar MS, Noailles L, Bonifer C. Role of AP-1
during haemogenic endothelium development.
Stanulovic V, Edginton-White B, Giorgiades E, Patani H, Cauchy P, Vijayabaskar MS, Bonifer C,
Rabbits T, Hoogenkamp M. Role of Lmo2 during early haematopoiesis and T-ALL.
Edginton-White B, Kwon SY, Burgin S, Cauchy P, Assi SA, Cockerill PN, Bonifer C. Aberrant
activation of long terminal repeat elements in hodgkin’s lymphoma
Kreher S, Li S, Lamprecht B, Cauchy P, Bonifer C. Specific binding of an IRF/AP-1 complex in
Hodgkin Lymphoma cells.
Gilmour J, Lichtinger M, Noailles L, Assi SA, Cauchy P, Redgrave L, Bonifer C. The role of Runx1 at
the onset of hematopoiesis.
Loke J, Imperato MR, Ptasinska A, Assi SA, Cauchy P, Griffith M, Raghavan M, Cockerill PN, Bonifer
C Identification of common and distinct epigenetic re-programming properties of Core-Binding
Factor Fusion Proteins.
Assi SA, Cauchy P, Allen K, Ptasinska A, Piper J, Ott S, Cockerill PN, Bonifer C. Identification of
regulatory signatures defines AML specificity.
Ladopoulos V, Moignard V, Hannah R, Cauchy P, Bonifer C, Göttgens B. Systematic
characterization of transcription factor signatures in mouse hematopoietic progenitors
Zacarias-Cabeza J, Imperato MR, Cauchy P, Bonifer C, Cockerill PN. Characterization of regulatory
signatures in FLT3-ITD cell lines.
Imperato MR, Zacarias-Cabeza J, Cauchy P, Piper J, Ott S, Bonifer C, Cockerill PN. Optimisation of
chromatin occupancy detection methods applied to digital genomic footprinting.
Gilding N, Zacarias-Cabeza J, Cauchy P, Piper J, Cockerill PN. Role of FOX and E-Box proteins in
FLT3-ITD AML
Cauchy P, Kahn-Perlès B, Imbert J, Ferrier P, Lecine P. 2HybridTools, an Handy Software to
Facilitate Clone Identification and Mutation Mapping from Yeast Two-Hybrid Screening.
Rosa F, Cauchy P, Rameil P, Algarté-Génin M, Bedotto M, Ferrier P, Imbert J. Identification of two
novel regulatory regions in the IL2RA gene locus.
Conference proceedings
Zacarias-Cabeza J*, Cauchy P*, James S*, Piper J, Ptasinska A, Imperato MR, Canestraro M, Assi
SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C, Cockerill PN. Activating FLT3-ITD receptor
mutations in AML are associated with a specific epigenetic signature composed of a discrete
subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs.
Experimental Hematology. 2014 Aug; 42(8):S67
Ptasinska A, Assi SA, Williamson D, Cauchy P, Tenen D, Cockerill P, Westhead D, Heidenreich O,
Bonifer C. Identification of a dynamic core transcriptional regulatory network for t(8;21) AML.
Experimental Hematology. 2013 Aug 41(8):S16
Obier N, Vijayabaskar MS, Pearson S, Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D,
Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional
programming of chromatin during early hematopoietic development. Epigenetics & Chromatin.
2013 Mar; 6(1):S1-P59
Cauchy P, James S, Canestraro M, Ptasinska A, Hoogenkamp M, Assi SA, Piper J, Westhead D,
Bonifer C, Cockerill PN. Runx1 and the molecular basis of AML heterogeneity. Experimental
Hematology. 2012 Aug; 40(8):S65-S66
Oral communications
Cauchy P, Kreher S, Bouhlel A, Lamprecht B, Li S, Hummel F, Köchert K, Anagnostopoulos I,
Hummel M, Hiscott J, Wenzel SS, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R,
Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S. Mapping of
transcription factor motifs in active chromatin identifies key regulators in human lymphoma.
Leukaemia & Lymphoma Research Grantholder’s day, Institute of Child Health, University College
London, London, UK. 2014 Nov
Cauchy P, James S, Zacarias-Cabeza J, Imperato M, Canestraro M, Ptasinksa M, Piper J,
Hoogenkamp M, Bonifer C, Cockerill PN. FLT3-ITD mutations in AML confer a specific gene
regulation signature. Postdoctoral Research Gala, University of Birmingham, Birmingham, UK. 2013
Jul
Cauchy P, Thieffry D, Imbert J, Andrau JC. Discovery of Novel Regulatory Elements in Breast
Cancer Induced Genes using ChIP-chip. Colloque de l’Ecole Doctorale, Université de la
Méditerranée, Marseille, France. 2008 Jun
Cauchy P, Rosa F, Bedotto M, Thieffry D, Imbert J. Discovery of Novel Cis-Regulatory Elements in
the IL2RA Gene and in IL-2 Co-expressed Genes. JOBIM, Marseille, France. 2007 Jul
Poster communications
Cauchy P, James S, Piper J, Zacarias-Cabeza J, Canestraro M, Ptasinska A, Imperato MR, Assi SA,
Hoogenkamp M, Westhead D, Ott S, Bonifer C, Cockerill PN. Activating FLT3-ITD receptor
mutations in AML are associated with a specific epigenetic signature composed of a discrete
subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. EMBL
Transcription and Chromatin, Heidelberg, Germany. 2014 Aug
Obier N, Vijayabaskar MS, Pearson S,Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D,
Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional
programming of chromatin during early hematopoietic development. EMBL Transcription and
Chromatin, Heidelberg, Germany. 2014 Aug
Bevington S, Cauchy P, Mirabella F, James S, Piper J, Ott S, Bonifer C, Cockerill PN. Identification
of DNA elements that maintain epigenetic memory in T cells. London Chromatin Club, King’s
College London, London, UK. 2014 July
Cauchy P, James S, Piper J, Ptasinska A, Zacarias-Cabeza J, Imperato MR, Canestraro M, Assi SA,
Hoogenkamp M, Westhead D, Ott S, Bonifer C, Cockerill PN. Activating FLT3-ITD receptor
mutations in AML are associated with a specific epigenetic signature composed of a discrete
subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. Modern
Trends in Human Leukemia & Cancer, Wilsede, Germany. 2014 Jun
Cauchy P, James S, Zacarias-Cabeza J, Imperato MR, Canestraro M, Ptasinksa M, Piper J,
Hoogenkamp M, Bonifer C, Cockerill PN. A FLT3-ITD AML specific transcriptional signature.
Birmingham Cancer Epigenetics Conference, Birmingham, UK. 2013 May
Obier N, Vijayabaskar MS, Pearson S,Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D,
Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional
programming of chromatin during early hematopoietic development. Epigenetics & Chromatin:
Interactions and Processes Conference, Harvard Medical School, Boston, USA. 2013 Mar
Obier N, Vijayabaskar MS, Pearson S,Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D,
Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional
programming of chromatin during early hematopoietic development. ISEH Conference,
Amsterdam, Netherlands. 2012 Aug
Cauchy P, James S, Canestraro M, Ptasinksa M, Hoogenkamp M, Assi SA, Piper J, Westhead D,
Bonifer C, Cockerill PN. A RUNX1-driven transcriptional signature in FLT3-ITD AML. ISEH
Conference, Amsterdam, Netherlands. 2012 Aug
Fenouil R, Cauchy P, Koch F, Descostes N, Cabeza JZ, Innocenti C, Ferrier P, Spicuglia S, Gut M,
Gut I, Andrau JC. CpG islands and GC content dictate nucleosome depletion in a transcription-
independent manner at mammalian promoters. EMBO Meeting, Heidelberg, Germany. 2012 Aug
Cauchy P, Fenouil R, Koch F, Gut M, Pekowska A, Spicuglia S, Gut I, Ferrier P, Andrau JC. Improved
methods for dynamic ChIP-Seq analysis at multiple developmental stages applied to a genome-
wide Ets1 screening. Wellcome Trust Functional Genomics & Systems Biology Workshop,
Cambridge, UK. 2011 Dec
Fenouil R, Koch F, Cauchy P, Gut M, Gut I, Eick D, Ferrier P. New bioinformatics tools for ChIP-
Seq data preprocessing and analysis. Cold Spring Harbor Laboratory Meeting: Genome
Informatics, New York, USA. 2009 Oct
Koch, F, Fenouil R, Cauchy P, Gut M, Albert TK, Heidermann M, Chapman RD, Santana A, Eick D,
Ferrier P, Andrau JC. High-resolution mapping of TBP and RNA polymerase II phosphorylated
isoforms in vivo reveals new features of initiation and elongation. Cold Spring Harbor Laboratory
Meeting: Mechanisms of Eukaryotic Transcription, New York, USA. 2009 Aug
Cauchy P, Thieffry D, Imbert J, Andrau JC. Discovery of Novel Regulatory Elements in Breast
Cancer Induced Genes using ChIP-chip. Colloque de l’Ecole Doctorale, Université de la
Méditerranée, Marseille, France. 2008 Jun
Cauchy P, Rosa F, Bedotto M, Thieffry , Imbert J. Discovery of Novel Cis-Regulatory Elements in
the IL2RA Gene and in IL-2 Co-expressed Genes. Keystone Lymphocyte Activation and Signaling
Symposium, Snowbird, USA. 2008 Feb
Cauchy P, Rosa F, Bedotto M, Thieffry D, Imbert J. Discovery of Novel Cis-Regulatory Elements in
the IL2RA Gene and in IL-2 Co-expressed Genes. JOBIM, Marseille, France. 2007 Jul
Contributions to oral communications at international conferences
Bonifer C, A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin 6, James S, ,
Hoogenkamp M, Tenen, Ott S, Westhead D, Cockerill PN, Heidenreich O. Reprogramming of
chromatin in Acute Myeloid Leukemia. Epigenetic control of hematopoiesis and leukemogenesis,
IGBMC, Strasbourg, France. 2015 Apr
Ptasinska, A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin 6, James S, ,
Hoogenkamp M, Tenen, Ott S, Westhead D, Cockerill PN, Heidenreich O, Bonifer C. Identification of
a Dynamic Core Transcriptional Network in t(8;21) AML Regulating Differentiation Block and
Self-Renewal. 56th Meeting and Exposition of the American Society of Hematology, San Francisco,
USA. 2014 Dec.
Cockerill PN, Cauchy P, James S, Piper J, Zacarias-Cabeza J, Canestraro M, Ptasinska A, Imperato
MR, Assi SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C. Activating FLT3-ITD receptor
mutations in AML are associated with a specific epigenetic signature composed of a discrete
subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs.
Molecular Haemotopoiesis 17, SOAS, London, UK. 2014 Oct
Bonifer C, A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin 6, James S, ,
Hoogenkamp M, Tenen, Ott S, Westhead D, Cockerill PN, Heidenreich O. Transcriptional
programming of chromatin in t(8;21) AML. 21
st
CHO congress, Grasse, France. 2014 Sep
Bonifer C, Ptasinska A, Assi SA, Martinez-Soria N, Piper J, Cauchy P, Imperato MR, Pickin A, James
SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich
O. Identification of a dynamic core transcriptional network in t(8;21) AML regulating
differentiation block and self-renewal. ISEH Conference, Montreal, Canada. 2014 Aug
Cockerill PN, Cauchy P, James S, Piper J, Zacarias-Cabeza J, Canestraro M, Ptasinska A, Imperato
MR, Assi SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C. Activating FLT3-ITD receptor
mutations in AML are associated with a specific epigenetic signature composed of a discrete
subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. Modern
Trends in Human Leukemia & Cancer, Wilsede, Germany. 2014 Jun
Bevington S, Cauchy P, Mirabella F, James S, Piper J, Ott S, Bonifer C, Cockerill PN. Identification
of DNA elements that maintain epigenetic memory in T cells. Cold Spring Harbor Gene
Expression & Signaling in the Immune System, New York, USA. 2014 Apr
Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M,
McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR,
Heidenreich O, Bonifer C. Transcriptional programming of chromatin in t(8;21) AML. ISEH
Conference, Vienna, Austria. 2013 Aug
Bevington S, Cauchy P, Mirabella F, James S, Piper J, Ott S, Bonifer C, Cockerill PN. Identification
of DNA elements that maintain epigenetic memory in T cells. FASEB Science Research
Conference, Epigenetics, Chromatin and Transcription, Nassau, Bahamas. 2013 Jun
Bonifer C , Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu
M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN,
Westhead DR, Heidenreich O. Transcriptional programming of chromatin in t(8;21) AML. Modern
Trends in Human Leukemia & Cancer, Wilsede, Germany. 2012 Jun
Peer-reviewing activity
12/2014: BMC Genomics
04/2010: BMC Bioinformatics
Teaching (~50 hours)
02/2015: Research taster for BMed students, University of Birmingham
11/2014: Lectures for BMed students, University of Birmingham: chromatin structure
12/2013: 2-day epigenetics masterclass, University of Birmingham, PhD MIBTP biosciences
11/2013: Lectures for BMed students, University of Birmingham: chromatin structure
02/2013: Practical supervision, University of Birmingham, 1st
year BSc Molecular Biology
12/2012: 2-day epigenetics masterclass, University of Birmingham, PhD MIBTP biosciences
11/2012: Lectures for BMed students, University of Birmingham: chromatin structure
05/2012: Career development workshop, University of Birmingham, BSc students (Paris XI)
11/2011: Lectures for BMed students, University of Birmingham: chromatin structure
05/2010: Lectures at BSc level at ESIL, University of Aix-Marseille II: Transcription regulation
Student supervision
Kate Allen, PhD Systems Biology, Warwick, 2014-to date
Naveen Lalli, MSc Systems Biology, Warwick, 2014
Benjamin Edginton-White, PhD Molecular biology, Birmingham, 2013-to date
Eligio Ianetti, 3-month internship, Epigenetics of Hodgkin Lymphoma, Birmingham, 2013
Lyndsey Wright, PhD MIBTP, Birmingham, 2013
Liam Redgrave, PhD MIBTP, Birmingham, 2013
Sarah Burgin, BMedSc Clinical Sciences, Birmingham, 2013
Charlène Innocenti, MRes Molecular Biology, Marseille, 2008
Aurélie Bergon, MRes Bioinformatics, Structural Biochemistry, Genomics, Marseille, 2008
Marielle Bedotto, MPro Bioinformatics, Structural Biochemistry, Genomics, Marseille, 2007
Training
04/2010: Data-morphing structures and Amadea at ISOFT, Gif s/ Yvette, France
05/2008: Scientific communication, Graduate School, Université d’Aix-Marseille II, France
04/2007: Dynamical modelling of biological regulatory networks, Les Houches, France
05/2004: Project work in behavioural ecology, CNRS UMR7372 CEBC, Chizé, France
02/2000: Medical bacteriology, H.I.A Val de Grâce, Paris, France
08/1998: Project work in evolutionary genetics in Sordaria sp., Imperial College, London, UK
Awards
06/2014: LLR Travel Grant, XX WILSEDE MEETING: “Modern trends in leukaemia and cancer”
04/2007: INRIA/EU Travel Grant, “Dynamical Modelling of Biological Regulatory Networks”
Certifications
02/2014: Qualification aux fonctions de maître de conférences (lectureship accreditation)
07/2004: Brevet d'aptitude aux fonctions d'animateur (youth supervision accreditation)
08/1998: Cambridge Certificate of Proficiency in English
Memberships
04/2012-present: International Society for Experimental Hematology
Languages
Bilingual: English, French, Italian
Fluent: German
Working proficiency: Spanish

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Pierre_Cauchy_Scientific_CV_complete

  • 1. Personal Details French national, 34 years old Address: 11 Grigg Grove, Birmingham B31 5HR Telephone: +44 (0) 121 477 2608 In partnership, one child Email: cauchyp@bham.ac.uk Scientific Background 2011-present: Postdoctoral Research Fellow in molecular haematopoiesis and oncology, Prof. Bonifer’s group, Cancer Sciences, University of Birmingham 2010: PhD Bioinformatics, Biochemistry, Genomics, Université Aix-Marseille. Title: "Role and transcriptional context of the transcription factor ETS1 during the DN/DP transition in αβ thymocyte differentiation", PhD supervised by Dr Andrau and Dr Imbert, CIML CNRS UMR6102/INSERM U631 and TAGC INSERM U928, Marseille, France 2006: MRes Bioinformatics, University of Glasgow. Research project: "Motif discovery in Interleukin 2 regulated genes", project work supervised by Dr Imbert, INSERM U599, Marseille, France 2004: MSc Biology, Université de La Rochelle, France 2000: Undergraduate Microbiology, Imperial College London, London, UK 1997: French Scientific Baccalaureate, Specialisation in Mathematics, “Mention Assez Bien” Expertise Wet lab: Chromatin immunoprecipitation (ChIP), ChIP-Seq, DNAseI-Seq, MNase-Seq, PCR, RT-qPCR, ChIP-chip and expression microarrays, cell culture, western blot, MACS sorting, FACS, animal experimentation, patient sample processing. Bioinformatics: ChIP-Seq, DNAse-Seq, MNase-Seq & RNA-Seq analysis, programming in Java, Perl, R, PHP ChIP-chip, expression & m5C microarray analysis, digital footprinting, motif discovery, sequence analysis, functional and comparative genomics; databases: MySQL, Oracle. Scientific Communication Published peer-reviewed publications Imperato MR, Cauchy P, Obier N, Cockerill PN, Bonifer C. The RUNX1- PU.1 axis in the control of hematopoiesis. Int J Hematol 2015 Mar 8. DOI: 10.1007/s12185-015-1762-8 [Epub ahead of print] Zacarias-Cabeza J, Behlocine M, Vanhille L, Cauchy P, Koch F, Fenouil R, Bergon A, Gut A, Gut I, Eick D, Imbert J, Ferrier P, Andrau JC, Spicuglia S. Transcription dependent generation of a specialized chromatin structure at the Tcrβ locus. J Immunol 2015 Mar 2. pii: 1400789. [Epub ahead of print] Pierre Cauchy, Molecular and Computational Biologist
  • 2. Obier N, Lin Q, Cauchy P, Hornich V, Zenke M, Becker M, Müller A. Polycomb protein EED is required for silencing of pluripotency genes upon ESC differentiation. Stem Cell Rev. 2015 Feb;11(1):50-61 Kreher S, Cauchy P, Bonifer C, Mathas S. Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF- κB! Cytokine. 2015 Jan 10. pii: S1043- 4666(14)00626-7 Kreher S, Bouhlel A, Cauchy P, Lamprecht B, Li S, Hummel F, Köchert K, Anagnostopoulos I, Hummel M, Hiscott J, Wenzel SS, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R, Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S. Mapping of transcription factor motifs in active chromatin identifies key regulators in human lymphoma. Proc Natl Acad Sci. 2014 Oct 6. pii: 201406985 Ptasinska A, Assi SA, Martinez-Soria N, Piper J, Cauchy P, Imperato MR, Pickin A, James SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O, Bonifer C. Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal. Cell Rep. 2014 Sep 17. pii: S2211-1247(14)00687-1 Drummond MW, Pocock C, Boissinot M, Mills J, Brown J, Cauchy P, Cross NC, Hartley S, Kell J, Szubert A, Cockerill PN, Bowen DT. A multi-centre phase 2 study of azacitidine in chronic myelomonocytic leukaemia. Leukemia. 2014 Jul;28(7):1570-2 Piper J, Elze M, Cauchy P, Cockerill PN, Bonifer C, Ott S. Wellington: A novel method for the accurate identification of digital genomic footprints from DNase-seq data. Nucleic Acids Res. 2013 Nov;41(21):e201 Fenouil R*, Cauchy P*, Koch F*, Descostes N, Cabeza JZ, Innocenti C, Ferrier P, Spicuglia S, Gut M, Gut I, Andrau JC. CpG islands and GC content dictate nucleosome depletion in a transcription- independent manner at mammalian promoters. Genome Res. 2012 Dec;22(12):2399-408 Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C. Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding. Leukemia. 2012 Aug;26(8):1829-41 Koch F, Fenouil R, Gut M, Cauchy P, Albert TK, Zacarias-Cabeza J, Spicuglia S, Heidemann M, Hintermair C, Eick D, Gut I, Ferrier P, Andrau JC. Transcription Initiation Platforms and GTF recruitment at tissue specific enhancers and promoters. Nat Struct Mol Biol. 2011 Jul 17;18(8):956-63 Cauchy P, Benoukraf T, Ferrier P. Processing ChIP-chip Data: From the Scanner to the Browser. Methods Mol Biol. 2011 719:251-68 Benoukraf T*, Cauchy P*, Fenouil R*, Jeanniard A, Koch F, Jaeger S, Thieffry D, Imbert J, Andrau JC, Spicuglia S, Ferrier P. CoCAS: a ChIP-on-Chip Analysis Suite. Bioinformatics. 2009 Apr 1; 25(7):954-5 *co-first author Manuscripts in revision Klein-Hessling S, Rudolf R, Muhammad K, Knobeloch KP, Maqbool MA, Cauchy P, Andrau JC, Avots A, Talora C, Ellenrieder V, Screpanti I, Serfling E, Patra AK. NFATc1 activity is critical for T cell development and to prevent both T cell lymphopenia and leukemia. Nat Commun Cauchy P, James S, Ptasinska A, Zacarias-Cabeza J, Imperato MR, Assi SA, Piper J, Canestraro M, Hoogenkamp M, Raghavan M, Loke C, Akiki S, Clokie S, Richards SR, Westhead D, Griffiths MJ, Ott S, Bonifer C, Cockerill PN. Chronic growth factor signaling in Acute Myeloid Leukemia is connected to a specific epigenetic signature. Cell Rep
  • 3. Cauchy P, Zacarias-Cabeza J, Vanhille L, Koch F, Fenouil R, Gut M, Gut I, Maqbool MA, Griffon A, Imbert J, Ferrier P, Spicuglia S, Andrau JC. Dynamic recruitment of Ets1 to both nucleosome - occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation. Nucleic Acids Res Manuscripts under review Piper J, Assi SA, Cauchy P, Ladroue C, Cockerill PN, Bonifer C, Ott, S. Differential DNase-seq footprinting identifies cell-type determining transcription factors. BMC Genomics Manuscripts submitted Bevington S, Cauchy P, Piper J, Bertrand E, Lalli N, Ott S, Bonifer C, Cockerill PN. Defining the molecular mechanisms underlying the epigenetic basis of immunological memory in T cells.Immunity Benoukraf T, Cauchy P, Bardet A, Le P, Jaeger S, Imbert J, Thieffry D, Graziani S, Ferrier P. A data‐morphing approach for the identification of transcription factor binding sites exploiting high‐throughput sequencing data. BMC Bioinformatics Manuscripts in preparation Benoukraf T, Spinelli L, Jaeger S, Cauchy P, Tenen DG, Imbert J, Thieffry D, Ferrier P, Van Helden J. Peak-footprints: A phylogenetic footprinting pipeline for identifying transcription factor binding targets from high-throughput chromatin immunoprecipitation (ChIP) profiles. Goode DK, Obier N, Vijayabaskar MS, Lichtinger M, Hannah, R, Lie-A-Ling M, Lilly AJ, Florowska M, Batta K, Challinor M, Wallace K, Assi SA, Cauchy P, Gilmour J, Hoogenkamp M, Westhead DR, Lacaud G, Kouskoff V, Göttgens B, Bonifer C. Comprehensive Genome-Scale Analysis Of A Complete Developmental Pathway. Obier N, Lichtinger M, Cauchy P, Assi SA, Vijayabaskar MS, Noailles L, Bonifer C. Role of AP-1 during haemogenic endothelium development. Stanulovic V, Edginton-White B, Giorgiades E, Patani H, Cauchy P, Vijayabaskar MS, Bonifer C, Rabbits T, Hoogenkamp M. Role of Lmo2 during early haematopoiesis and T-ALL. Edginton-White B, Kwon SY, Burgin S, Cauchy P, Assi SA, Cockerill PN, Bonifer C. Aberrant activation of long terminal repeat elements in hodgkin’s lymphoma Kreher S, Li S, Lamprecht B, Cauchy P, Bonifer C. Specific binding of an IRF/AP-1 complex in Hodgkin Lymphoma cells. Gilmour J, Lichtinger M, Noailles L, Assi SA, Cauchy P, Redgrave L, Bonifer C. The role of Runx1 at the onset of hematopoiesis. Loke J, Imperato MR, Ptasinska A, Assi SA, Cauchy P, Griffith M, Raghavan M, Cockerill PN, Bonifer C Identification of common and distinct epigenetic re-programming properties of Core-Binding Factor Fusion Proteins. Assi SA, Cauchy P, Allen K, Ptasinska A, Piper J, Ott S, Cockerill PN, Bonifer C. Identification of regulatory signatures defines AML specificity. Ladopoulos V, Moignard V, Hannah R, Cauchy P, Bonifer C, Göttgens B. Systematic characterization of transcription factor signatures in mouse hematopoietic progenitors Zacarias-Cabeza J, Imperato MR, Cauchy P, Bonifer C, Cockerill PN. Characterization of regulatory signatures in FLT3-ITD cell lines. Imperato MR, Zacarias-Cabeza J, Cauchy P, Piper J, Ott S, Bonifer C, Cockerill PN. Optimisation of chromatin occupancy detection methods applied to digital genomic footprinting.
  • 4. Gilding N, Zacarias-Cabeza J, Cauchy P, Piper J, Cockerill PN. Role of FOX and E-Box proteins in FLT3-ITD AML Cauchy P, Kahn-Perlès B, Imbert J, Ferrier P, Lecine P. 2HybridTools, an Handy Software to Facilitate Clone Identification and Mutation Mapping from Yeast Two-Hybrid Screening. Rosa F, Cauchy P, Rameil P, Algarté-Génin M, Bedotto M, Ferrier P, Imbert J. Identification of two novel regulatory regions in the IL2RA gene locus. Conference proceedings Zacarias-Cabeza J*, Cauchy P*, James S*, Piper J, Ptasinska A, Imperato MR, Canestraro M, Assi SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C, Cockerill PN. Activating FLT3-ITD receptor mutations in AML are associated with a specific epigenetic signature composed of a discrete subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. Experimental Hematology. 2014 Aug; 42(8):S67 Ptasinska A, Assi SA, Williamson D, Cauchy P, Tenen D, Cockerill P, Westhead D, Heidenreich O, Bonifer C. Identification of a dynamic core transcriptional regulatory network for t(8;21) AML. Experimental Hematology. 2013 Aug 41(8):S16 Obier N, Vijayabaskar MS, Pearson S, Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D, Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional programming of chromatin during early hematopoietic development. Epigenetics & Chromatin. 2013 Mar; 6(1):S1-P59 Cauchy P, James S, Canestraro M, Ptasinska A, Hoogenkamp M, Assi SA, Piper J, Westhead D, Bonifer C, Cockerill PN. Runx1 and the molecular basis of AML heterogeneity. Experimental Hematology. 2012 Aug; 40(8):S65-S66 Oral communications Cauchy P, Kreher S, Bouhlel A, Lamprecht B, Li S, Hummel F, Köchert K, Anagnostopoulos I, Hummel M, Hiscott J, Wenzel SS, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R, Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S. Mapping of transcription factor motifs in active chromatin identifies key regulators in human lymphoma. Leukaemia & Lymphoma Research Grantholder’s day, Institute of Child Health, University College London, London, UK. 2014 Nov Cauchy P, James S, Zacarias-Cabeza J, Imperato M, Canestraro M, Ptasinksa M, Piper J, Hoogenkamp M, Bonifer C, Cockerill PN. FLT3-ITD mutations in AML confer a specific gene regulation signature. Postdoctoral Research Gala, University of Birmingham, Birmingham, UK. 2013 Jul Cauchy P, Thieffry D, Imbert J, Andrau JC. Discovery of Novel Regulatory Elements in Breast Cancer Induced Genes using ChIP-chip. Colloque de l’Ecole Doctorale, Université de la Méditerranée, Marseille, France. 2008 Jun Cauchy P, Rosa F, Bedotto M, Thieffry D, Imbert J. Discovery of Novel Cis-Regulatory Elements in the IL2RA Gene and in IL-2 Co-expressed Genes. JOBIM, Marseille, France. 2007 Jul Poster communications Cauchy P, James S, Piper J, Zacarias-Cabeza J, Canestraro M, Ptasinska A, Imperato MR, Assi SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C, Cockerill PN. Activating FLT3-ITD receptor mutations in AML are associated with a specific epigenetic signature composed of a discrete
  • 5. subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. EMBL Transcription and Chromatin, Heidelberg, Germany. 2014 Aug Obier N, Vijayabaskar MS, Pearson S,Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D, Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional programming of chromatin during early hematopoietic development. EMBL Transcription and Chromatin, Heidelberg, Germany. 2014 Aug Bevington S, Cauchy P, Mirabella F, James S, Piper J, Ott S, Bonifer C, Cockerill PN. Identification of DNA elements that maintain epigenetic memory in T cells. London Chromatin Club, King’s College London, London, UK. 2014 July Cauchy P, James S, Piper J, Ptasinska A, Zacarias-Cabeza J, Imperato MR, Canestraro M, Assi SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C, Cockerill PN. Activating FLT3-ITD receptor mutations in AML are associated with a specific epigenetic signature composed of a discrete subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. Modern Trends in Human Leukemia & Cancer, Wilsede, Germany. 2014 Jun Cauchy P, James S, Zacarias-Cabeza J, Imperato MR, Canestraro M, Ptasinksa M, Piper J, Hoogenkamp M, Bonifer C, Cockerill PN. A FLT3-ITD AML specific transcriptional signature. Birmingham Cancer Epigenetics Conference, Birmingham, UK. 2013 May Obier N, Vijayabaskar MS, Pearson S,Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D, Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional programming of chromatin during early hematopoietic development. Epigenetics & Chromatin: Interactions and Processes Conference, Harvard Medical School, Boston, USA. 2013 Mar Obier N, Vijayabaskar MS, Pearson S,Hoogenkamp M, Lichtinger M, Cauchy P, Westhead D, Kouskoff D, Lacaud G, Gottgens N, Bonifer C. System-wide studies of the transcriptional programming of chromatin during early hematopoietic development. ISEH Conference, Amsterdam, Netherlands. 2012 Aug Cauchy P, James S, Canestraro M, Ptasinksa M, Hoogenkamp M, Assi SA, Piper J, Westhead D, Bonifer C, Cockerill PN. A RUNX1-driven transcriptional signature in FLT3-ITD AML. ISEH Conference, Amsterdam, Netherlands. 2012 Aug Fenouil R, Cauchy P, Koch F, Descostes N, Cabeza JZ, Innocenti C, Ferrier P, Spicuglia S, Gut M, Gut I, Andrau JC. CpG islands and GC content dictate nucleosome depletion in a transcription- independent manner at mammalian promoters. EMBO Meeting, Heidelberg, Germany. 2012 Aug Cauchy P, Fenouil R, Koch F, Gut M, Pekowska A, Spicuglia S, Gut I, Ferrier P, Andrau JC. Improved methods for dynamic ChIP-Seq analysis at multiple developmental stages applied to a genome- wide Ets1 screening. Wellcome Trust Functional Genomics & Systems Biology Workshop, Cambridge, UK. 2011 Dec Fenouil R, Koch F, Cauchy P, Gut M, Gut I, Eick D, Ferrier P. New bioinformatics tools for ChIP- Seq data preprocessing and analysis. Cold Spring Harbor Laboratory Meeting: Genome Informatics, New York, USA. 2009 Oct Koch, F, Fenouil R, Cauchy P, Gut M, Albert TK, Heidermann M, Chapman RD, Santana A, Eick D, Ferrier P, Andrau JC. High-resolution mapping of TBP and RNA polymerase II phosphorylated isoforms in vivo reveals new features of initiation and elongation. Cold Spring Harbor Laboratory Meeting: Mechanisms of Eukaryotic Transcription, New York, USA. 2009 Aug
  • 6. Cauchy P, Thieffry D, Imbert J, Andrau JC. Discovery of Novel Regulatory Elements in Breast Cancer Induced Genes using ChIP-chip. Colloque de l’Ecole Doctorale, Université de la Méditerranée, Marseille, France. 2008 Jun Cauchy P, Rosa F, Bedotto M, Thieffry , Imbert J. Discovery of Novel Cis-Regulatory Elements in the IL2RA Gene and in IL-2 Co-expressed Genes. Keystone Lymphocyte Activation and Signaling Symposium, Snowbird, USA. 2008 Feb Cauchy P, Rosa F, Bedotto M, Thieffry D, Imbert J. Discovery of Novel Cis-Regulatory Elements in the IL2RA Gene and in IL-2 Co-expressed Genes. JOBIM, Marseille, France. 2007 Jul Contributions to oral communications at international conferences Bonifer C, A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin 6, James S, , Hoogenkamp M, Tenen, Ott S, Westhead D, Cockerill PN, Heidenreich O. Reprogramming of chromatin in Acute Myeloid Leukemia. Epigenetic control of hematopoiesis and leukemogenesis, IGBMC, Strasbourg, France. 2015 Apr Ptasinska, A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin 6, James S, , Hoogenkamp M, Tenen, Ott S, Westhead D, Cockerill PN, Heidenreich O, Bonifer C. Identification of a Dynamic Core Transcriptional Network in t(8;21) AML Regulating Differentiation Block and Self-Renewal. 56th Meeting and Exposition of the American Society of Hematology, San Francisco, USA. 2014 Dec. Cockerill PN, Cauchy P, James S, Piper J, Zacarias-Cabeza J, Canestraro M, Ptasinska A, Imperato MR, Assi SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C. Activating FLT3-ITD receptor mutations in AML are associated with a specific epigenetic signature composed of a discrete subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. Molecular Haemotopoiesis 17, SOAS, London, UK. 2014 Oct Bonifer C, A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin 6, James S, , Hoogenkamp M, Tenen, Ott S, Westhead D, Cockerill PN, Heidenreich O. Transcriptional programming of chromatin in t(8;21) AML. 21 st CHO congress, Grasse, France. 2014 Sep Bonifer C, Ptasinska A, Assi SA, Martinez-Soria N, Piper J, Cauchy P, Imperato MR, Pickin A, James SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O. Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal. ISEH Conference, Montreal, Canada. 2014 Aug Cockerill PN, Cauchy P, James S, Piper J, Zacarias-Cabeza J, Canestraro M, Ptasinska A, Imperato MR, Assi SA, Hoogenkamp M, Westhead D, Ott S, Bonifer C. Activating FLT3-ITD receptor mutations in AML are associated with a specific epigenetic signature composed of a discrete subset RUNX1-bound DNaseI hypersensitive sites enriched for AP-1 and C/EBP motifs. Modern Trends in Human Leukemia & Cancer, Wilsede, Germany. 2014 Jun Bevington S, Cauchy P, Mirabella F, James S, Piper J, Ott S, Bonifer C, Cockerill PN. Identification of DNA elements that maintain epigenetic memory in T cells. Cold Spring Harbor Gene Expression & Signaling in the Immune System, New York, USA. 2014 Apr Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C. Transcriptional programming of chromatin in t(8;21) AML. ISEH Conference, Vienna, Austria. 2013 Aug
  • 7. Bevington S, Cauchy P, Mirabella F, James S, Piper J, Ott S, Bonifer C, Cockerill PN. Identification of DNA elements that maintain epigenetic memory in T cells. FASEB Science Research Conference, Epigenetics, Chromatin and Transcription, Nassau, Bahamas. 2013 Jun Bonifer C , Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O. Transcriptional programming of chromatin in t(8;21) AML. Modern Trends in Human Leukemia & Cancer, Wilsede, Germany. 2012 Jun Peer-reviewing activity 12/2014: BMC Genomics 04/2010: BMC Bioinformatics Teaching (~50 hours) 02/2015: Research taster for BMed students, University of Birmingham 11/2014: Lectures for BMed students, University of Birmingham: chromatin structure 12/2013: 2-day epigenetics masterclass, University of Birmingham, PhD MIBTP biosciences 11/2013: Lectures for BMed students, University of Birmingham: chromatin structure 02/2013: Practical supervision, University of Birmingham, 1st year BSc Molecular Biology 12/2012: 2-day epigenetics masterclass, University of Birmingham, PhD MIBTP biosciences 11/2012: Lectures for BMed students, University of Birmingham: chromatin structure 05/2012: Career development workshop, University of Birmingham, BSc students (Paris XI) 11/2011: Lectures for BMed students, University of Birmingham: chromatin structure 05/2010: Lectures at BSc level at ESIL, University of Aix-Marseille II: Transcription regulation Student supervision Kate Allen, PhD Systems Biology, Warwick, 2014-to date Naveen Lalli, MSc Systems Biology, Warwick, 2014 Benjamin Edginton-White, PhD Molecular biology, Birmingham, 2013-to date Eligio Ianetti, 3-month internship, Epigenetics of Hodgkin Lymphoma, Birmingham, 2013 Lyndsey Wright, PhD MIBTP, Birmingham, 2013 Liam Redgrave, PhD MIBTP, Birmingham, 2013 Sarah Burgin, BMedSc Clinical Sciences, Birmingham, 2013 Charlène Innocenti, MRes Molecular Biology, Marseille, 2008 Aurélie Bergon, MRes Bioinformatics, Structural Biochemistry, Genomics, Marseille, 2008 Marielle Bedotto, MPro Bioinformatics, Structural Biochemistry, Genomics, Marseille, 2007 Training 04/2010: Data-morphing structures and Amadea at ISOFT, Gif s/ Yvette, France 05/2008: Scientific communication, Graduate School, Université d’Aix-Marseille II, France 04/2007: Dynamical modelling of biological regulatory networks, Les Houches, France 05/2004: Project work in behavioural ecology, CNRS UMR7372 CEBC, Chizé, France 02/2000: Medical bacteriology, H.I.A Val de Grâce, Paris, France 08/1998: Project work in evolutionary genetics in Sordaria sp., Imperial College, London, UK Awards
  • 8. 06/2014: LLR Travel Grant, XX WILSEDE MEETING: “Modern trends in leukaemia and cancer” 04/2007: INRIA/EU Travel Grant, “Dynamical Modelling of Biological Regulatory Networks” Certifications 02/2014: Qualification aux fonctions de maître de conférences (lectureship accreditation) 07/2004: Brevet d'aptitude aux fonctions d'animateur (youth supervision accreditation) 08/1998: Cambridge Certificate of Proficiency in English Memberships 04/2012-present: International Society for Experimental Hematology Languages Bilingual: English, French, Italian Fluent: German Working proficiency: Spanish