Scientific Publications and Scholarly National and International Presentations
List of Publications_Dr Kerrie Smith
1. Original research papers in peer-reviewedjournals:
1) Mouapi K.N,Bell J.D, Smith K.A, Ariëns R.A.S,PhilippouH,MaurerM.C. CharacterizingReactive
Glutaminesinthe FibrinogenαCRegiontoProbe forSourcesof Factor XIIISubstrate Specificity.
Blood(2016);127(18):2241-8
2) AveryC.A,Pease R.J, SmithK.A, BoothbyM, WhitwoodH.M,Grant P.J, andFishwickC.W.G.(±)
cis-Bisamidoepoxides:A novel seriesof potentFXIII-A inhibitors.EuropeanJournal of Medicinal
Chemistry. (2015) Jun 15;98:49-53
3) Cordell P.A,Newell L.M,StandevenK.F,AdamsonP.J,SimpsonK.R, SmithK.A, JacksonC.L,
Grant P.J,Pease R.J.Normal Bone DepositionoccursinMice DeficientinFactorXIII-A and
Transglutaminase 2.Matrix Biology. (2015) Apr;43:85-96.
4) AjjanR.A,GamlenT, StandevenK.F,Mughal S,HessK, Smith K.A, DunnE.J, AnwarM.M,
Rabbani N,ThornalleyP.J,PhilippouHandGrant P.J.Diabetesisassociatedwithpost-
translational modificationsinplasminogennresultinginreducedplasmingenerationand
enzyme specificactivity.Blood. (2013) Jul 4;122(1):134-42
5) Smith K.A, Pease R.J,AveryC.A,BrownJ.M,AdamsonP.J,Cooke E.J, Neergaard-PetersenS,
Cordell PA,AriënsR.A.S,FishwickC.W.G,PhilippouH,Grant P.J.The ActivationPeptide Cleft
ExposedbyThrombinCleavage of FXIII-A2ContainsaRecognitionSiteforthe Fibrinogenα
Chain.Blood. (2013) Mar 14;121(11):2117-26. Editorial: KohlerHP.InteractionbetweenFXIII
and fibrinogen.Blood. (2013) Mar 14;121(11):1931-2.
6) HooperJ.M.W, StuijverD.J.F,Orme S.M,Zaane vanB, HessK, GerdesV.E,Phoenix F,Rice P,
Smith K.A, Alzahrani S,Standeven K.F,andAjjanR.A.Thyroiddysfunctionandfibrinnetwork
structure:A mechanismforincreasedthromboticriskinhyperthyroidindividuals.The Journal of
Clinical Endocrinology&Metabolism (2012) May;97(5):1463-73.
7) HowesJ,RichardsonV.R, Smith K.A, SchroederV,Somani R,Shore A,HessK, AjjanR, Pease R.J,
KeenJ.N,StandevenK.F,GrantP.J,CarterA.M. ComplementC3isa Novel PlasmaClot
ComponentwithAnti-FibrinolyticProperties.DiabVascDisRes. (2012) Jul;9(3):216-25.
8) HessK, Alzahrani S,Mathai M, SchroederV,CarterA.M, Howell G,KokoT, Strachan M.W.J,
Price J.F, Smith K.A, Grant P.J,AjjanR.A.A novel mechanismforhypofibrinolysisindiabetes:
The role of ComplementC3.Diabetologia. (2012) Apr;55(4):1103-13.
9) Smith K.A, AdamsonP.J,Pease R.J,BalmforthA.J,BrownJ.M,AriensR.A.S,CordellP.A,
PhilippouH,GrantP.J.InteractionsbetweenfactorXIIIandthe αCregionof fibrinogen.Blood.
(2011) Mar 24;117(12):3460-8. Editorial: Lord ST. Coming full circle with factor XIII. Blood. (2011)
Mar 24;117(12):3255-6.
Invitedreviewarticles
RichardsonV.R, SmithK.A*, and Carter A.M*. Adipose Tissue Inflammation:Feedingthe
Developmentof Type 2DiabetesMellitus.Invitedreview. Immunobiology. (2013) Dec;
218(12):1497-504
2. Conference proceedings
1. Mouapi,K. N., Smith,K. A.,Ariens,R.A.S., Philippou,H.,&Maurer, M. C.(2016).
Transglutaminase FactorXIIICross-LinksReactive GlutaminesinDisorderedRegionsof
Fibrinogen alphaC.InBiophysical Journal.Vol.110(pp.549A).
2. Simpson,K.R.,Beckers,C.M., Griffin,K.J.,Brown,J., Cordell,P.A., Smith,K.A., Grant, P. J.
(2015). Residenttissue macrophagesare the probable source of plasmaclottingfactorXIII-A.In
Journal of Thrombosis& HaemostasisVol.13(pp.820-821).
3. Schuett,K.,King,R.,Phoenix,F., Smith,K.A.,Maxeiner,S.,Lysaja,K.,Ajjan,R.(2015).
ComplementC3and hypofibrinolysis:apotential role forproteinglycation.InJournal of
Thrombosis&HaemostasisVol.13 (pp.675).
4. Mouapi,K. N.,Bell,J., Smith,K.A.,Ariens,R.,Philippou,H.,&Maurer, M. (2015). Characterizing
reactive glutaminesinfibrinogenalphaC(233-425) and probingfactorXIIIsubstrate specificity.
In Journal of Thrombosis&HaemostasisVol.13 (pp.238).
5. Cordell,P.A.,Newell,L.M., Standeven,K.F.,Adamson,P.J.,Simpson,K.R., Smith,K. A.,Pease,
R. J. (2015). Normal Bone DepositionOccursinMice DeficientinFactorXIII-A and
Transglutaminase 2.InMatrix BiologyVol.43(pp.85-96).
6. Mouapi,K. N.,Bell,J., Smith,K. A, Philippou,H.,Ariens,R.,&Maurer,M. (2015). ProbingFactor
XIIISubstrate SpecificityforFibrinogenalphaC(233-425) Using Maldi-Tof Mass Spectrometry
and 2D 15N-1H HSQC NMR Spectroscopy.InBiophysical Journal Vol.108 (pp.531A).
7. Cooke E. J, Cordell P. A, Pease R. J, Brown J. M, Beckers C. M, Simpson K. R, Grant P. J, Smith K.A.
(2015). Characterisationof cellularfibrinogenphosphorylationanditsfunctional implicationsin
clot formation.InJournal of Thrombosis&Haemostasis.Vol.13(Suppl.2) 1–997.
8. Cooke E.J,Cordell P.A,Pease R.J,Grant P.J, Smith K. A. (2013) Detection,localisationand
quantificationof intracellularphosphorylatedhumanfibrinogenbyproximityligation:anovel
approach forthe characterisationof fibrinogenphosphorylation.InJournal of Thrombosis&
HaemostasisVol.11,978-978.
9. Cordell,P.A., Smith,K. A.,Pease,R.J., & Grant, P. J.(2013). Tyrosine phosphorylationof
macrophage factor XIII-A:apotential mechanismforcontrollingintracellularenzyme activation
and localization.InJournal of Thrombosis&HaemostasisVol.11(pp.830-831).
10. Carter,A. M., Schroeder,V.,Polkinghorne,V.R., Smith,K. A.,Somani,R.,Standeven,K.F.,&
Grant, P. J.(2009). The InflammatoryProteinComplementC3is a Novel Substrate forFactorXIII
and ImpairsFibrinClotLysis.InCirculationVol.120 (pp.S1099).
11. Smith K.A, AdamsonP.JAriensR.A.S,PhilippouH,Grant P.J.(2008). Role of the Fibrinogen
AlphaChaininControllingthe Rate of FactorXIIIActivation:ImplicationsforCoronaryArtery
ThrombusFormation.InCirculationVol.118(Suppl 18), S_363-S_363.
12. Smith K.A, AdamsonP.JAriensR.A.S,PhilippouH,Grant P.J.(2008). The role of the fibrinogen
alphachainin controllingthe rate of FXIIIactivation:Implicationsforcoronaryarterythrombus
formation.InHeartVol.94, A51-A51.