The final presentation of biotechnology cluster team in the program "Youth and clusters: do clusters visible Russian and global. Samara region - 2014." Submitted materials are developed by program participants - students under the guidance of professional curators in the first phase of the program "Charting clusters" which was held from March 25 to April 22, 2014. The team was tasked with: • create a map of the enterprises and organizations of their cluster, • determine the main directions of development of the industry in the region • answer the question: "What are the competitive capabilities of the Samara region on the economic direction?" September 15, 2014 starts a new stage of program "Charting the Trends" Participants are welcome! Participation in the program For participation in the program, press accreditation and conducting of the program in your region, please contact: smklaster@gmail.com

1. Biotechnological clusterBiotechnological cluster
of Samara Regionof Samara Region
Samara State Technical University
Samara State Medical University
Samara tissue вank
Program “Youth and Clusters:
Making clusters of Russia visible and globally competitive”
Samara region, April 2014

2. Bioresource
Microorganisms
Plant cells
Animal and human
cells
Nucleic acids: DNA
and RNA
Cell features:
-Paladeses glanules
-Mitochondrions
-Chloroplast, etc.

3. Using of biological objects and products of their life to
get useful solutions for usage in various areas.
BiotechnologyBiotechnology
Applicable scope

4. Before Pasteur period: before 1865 (before Paster’s invention of
microcosm in 1865) – bread making, lactic-acid fermentation,
production of vinegar, cheese, alcohol invention.
After Pasteur period: 1866 – 1940 – production of butanol, acetone,
anatoxins, vaccines, whey and other goods by using biosynthetic skills
of bacteria.
Period of antibiotics: 1941 – 1960 – invention of antibiotics; invention
of DNA.
Period of controlled biosynthesis: 1961 – 1975: the skill of bacteria
to hyperexpression of certain materials(amino acid, vitamins, etc.) was
invented.
Period of new biotechnology: after 1975 – modern achievements in
genetic and cell ingeneering.
Historical backgroundHistorical background of biotech in the Worldof biotech in the World

5.  Nutritional
Biotechnologies in Samara regionBiotechnologies in Samara region
Ecological
 Medical

6. Nutrition biotechnology
Problems:
Shortage of protein in nutrition
Shortage of vitamins in nutrition
Production of eco-friendly products

7. Samara RegionSamara Region

8.  Samara bakery № 2 was established in 1933
 OJSC «Тolyattikhleb» was established in 1952
 Samara bakery № 5 was established in 1956
 Samara bakery and confectionery complex was established
in 1988
NutritionalNutritional:: bread makingbread making

9. OJSC "Unimilk" branch MK "Samaralakto" was established in 1932
ОJSC "Koshkinsky of Maslosyrzavod"was established in 2002
LLC Company "Moltorg" was established in 1997
NutritionalNutritional:: production of fermented milk productsproduction of fermented milk products

10. OJSC "Zhigulevskoe Pivo“ was established in1881
OJSC "Samara-Baltica" was established in 2003
OJSC "Factory of sparkling wines and brandies
“Rosinka" (Togliatti) was established in 1980
NutririonalNutrirional:: technology of fermentation industrytechnology of fermentation industry

11.  Laboratory of remaking alimentary raw
materials technologies
 Mini-brewery
 Laboratory of milk remaking
Working process on the basket press –
remaking of apples, growing on the
territory of SBE SR RI
horticultural and medicinal plants "Zhiguli
Valley"
NutritionalNutritional:: Innovative technologies in SSTUInnovative technologies in SSTU

12. Ecological biotechnology
Problems:
Pollution of water, air, soil
Non eco-friendly technologies in manufacturing
industrial goods

13. Waste treatment facilities : Samara, Kinel, Otradnyi, Novokuibyshevsk,
Togliatti, Chapaevsk and others.
Waste treatment facilities of plants:
Kuibyshev oil refinery(Samara), Syzran oil refinery, Novokuibyshevsk oil
refinery, Brewing company «Samara-Baltika»
EcologicalEcological:: tertiary treatmenttertiary treatment

14. Chemicals:
Use of biocatalists in synthesis of new conjugations;
Decrease of byproduct amount;
Increase of production purification rate.
Energetical industry:
Use of ferments to make eco-friendly firing out of agricultural
residues
Increasing environmental friendliness for industrialIncreasing environmental friendliness for industrial
technologiestechnologies
Petrochemical industry:
Biological recultivation technology of oil-
contaminated soil with the help of brewery
wastes(SSTU)

15. Problems:
Increase of injury rate
Oncology
Diseases caused by ecological problems
Medical biotechnologies

16. Opthalmic bank in Eroshevskyi Regional Clinical Opthalmological
Hospital was established in 1973 г.
Its main scientific-practical orientation -
preparation and preservation method
siliconisation of cornea, sclera and amnion
MedicalMedical:: histologic technologieshistologic technologies

17.  10 patents to the technologies of getting cell;
 More than 30 patents to the ways of clinical
use;
 Producing of 100 variants of bioimplants
out of ostein, sinew, fascia, pachymeninx.
Samara State Medical University,
Samara tissue вank was established in 1983 г.:
LYOPHILIZED BIOIMPLANTS "LITOPLAST"®
,
MedicalMedical:: histologic technologieshistologic technologies

18. Samara State Medical University,
Laboratory of cell cultures, was established in 2000
Исследование In vitro на клетках – наиболее этичный метод
исследований на живых объектах!
MedicalMedical:: histologic technologieshistologic technologies

19.  New way of recovery after traumatic lesion of
arthrodial cartilage with the help of allogenic histologic
technologies and video endoscope tools was invented.
Sport
accidents
Video image
endoscopy
Laboratory of cell
culture
Creation of new medical technologiesCreation of new medical technologies

20. MedicalMedical:: cell testscell tests
Panel of cell population in culture for osteoplastic material test, metal
products for osteosynthesis and dental implants.
Macrophages Mesenchimal stromal cells of marrow
Fibroblasts Chondroblast Osteoblast

21. MedicalMedical:: histologic technologieshistologic technologies
Kalinin Samara Region Clinical Hospital
“Center of marrow transplantation and cell-based therapy”
Marrow exfusion
Head of department V.A. Rossievand I.A. Aleksandrova

22. Medical company IDK
Since 1988 OJSC Medical company IDK
has been curing reproductive pathology with
the help of in vitro fertilization(IVF).
This allows thousands of women become
mothers.
Руководитель компании – к.м.н. В.И. Карнаух
ECO
MedicalMedical:: histologic technologieshistologic technologies

23. Key goals:
Delivery of hi-tech health care with the help of histologic technologies for
Samara region citizens;
Development of new bioplastic materials based on umbilical blood plasm.
Crioreservoir for specs of placental blood
Clinical center of histologic technologies(2003 г.)
MedicalMedical:: histologic technologieshistologic technologies

24. Launch of ILV Soyuz-u" with
SPACECRAFT "Bion-M" №1
19 April 2013
Equipment SPACECRAFT "Bion-M"
№ 1 bio-objects and animals
Space medicineSpace medicine

25. TeamTeam ««BIORESOURCEBIORESOURCE»»
Samara State Technical
University
Zudina Anastasia - student
Elena Savenkova - student
Sukhanova Daria - student
Klein Yana - student
Melentieva Anastasia - postgrad
Kiseleva Natalia – postgrad
Samara State
Economic University
Ulanova Elena – student
Sharenkova Polina - student
Mentor- Candidate of Pharmaceutical Sciences, A.P. Zinaida
Маshchenko, mzinaida@yandex.ru
Samara State Medical
University
Krivchenko Kirill - postgraduate
Viktor Ivanov -postgraduate
Andrei Nikolaenko -postgraduate
Werbowski Alexey – postgraduate
Sharafutdinova Anastasia– postgraduate
Mentor- Candidate of Medical Sciences, professor Larisa Volova,
csrl.sam@mail.ru

26. Thank you for your
attention!