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Stefanadis C et al, J Am Col Cardiol 2001 April
ΔΤ - Percutanenous Coronary InterventionsΔΤ - Percutanenous Coronary Interventions
Coronary Thermography
• Thermal heterogeneity exists in vivo in
atherosclerotic plaque
• Statins decrease thermal heterogeneity possibly
by anti-inflammatory mechanism
• Thermal heterogeneity in the culprit lesion is a
prognostic factor for adverse cardiac events after
percutaneous interventions
• Is thermal heterogeneity a sensitive marker for
future cardiac events?
Primary end point: Death, MI, TLR in 12 months
Secondary end points:
-Procedural complications
-Cost effectiveness over 12 months
Stenting of culprit lesion only Stenting of culprit + non-culprit lesions
Randomization
Non-culprit lesion(s) with > 0.10O
C ∆T
Patients with ACS and multivessel disease
THERMO ACS:
Culprit or Multivessel Revascularization based on
Thermography in patients with ACS
…… Thermography Beyond Coronary ArteriesThermography Beyond Coronary Arteries

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4

  • 1. Stefanadis C et al, J Am Col Cardiol 2001 April ΔΤ - Percutanenous Coronary InterventionsΔΤ - Percutanenous Coronary Interventions
  • 2. Coronary Thermography • Thermal heterogeneity exists in vivo in atherosclerotic plaque • Statins decrease thermal heterogeneity possibly by anti-inflammatory mechanism • Thermal heterogeneity in the culprit lesion is a prognostic factor for adverse cardiac events after percutaneous interventions • Is thermal heterogeneity a sensitive marker for future cardiac events?
  • 3. Primary end point: Death, MI, TLR in 12 months Secondary end points: -Procedural complications -Cost effectiveness over 12 months Stenting of culprit lesion only Stenting of culprit + non-culprit lesions Randomization Non-culprit lesion(s) with > 0.10O C ∆T Patients with ACS and multivessel disease THERMO ACS: Culprit or Multivessel Revascularization based on Thermography in patients with ACS
  • 4. …… Thermography Beyond Coronary ArteriesThermography Beyond Coronary Arteries