Nanoliposomes-for-Cosmetics.pdf

About Us
CD Bioparticles is an established drug delivery company which provides customized
solutions for developing and producing new, biocompatible drug delivery systems.
CD Bioparticles offers both products and services to support cosmetic formulation
development. In cosmetics, since skin is the first defensive barrier against external
factors and prevents many substances from entering the underlying layers or
systemic circulation, there are some limitations to deliver the active ingredient to
the target site. By using liposomes, we are able to overcome some restrictions such
as low penetration, solubility, stability, duration of effect and high side effects or
costs, and improve some other characteristics. Liposome-encapsulation largely
reduces the amount of the active ingredient required for effectiveness as compared
to non-encapsulated, pure active ingredients.
We offer fully certified high-quality nanoliposomes for cosmetics.
• Use FDA GRAS grade materials for high safety.
• Nanoliposomes have good heat, PH and shear stability and is easy to use.
• Many types of nanoliposomes encapsulate different natural active
substances to match customers' needs.
• Provide GMP grade nanoliposomes.
• Immediate and expert scientific support.
Today we offer you:

Table of Contents
Clipos™ Nanoliposomal Resveratrol ................................................................................... 4
Clipos™ Nanoliposomal THC ................................................................................................5
Clipos™ Nanoliposomal Vitamin A Palmitate ....................................................................6
Clipos™ Nanoliposomal Vitamin C ......................................................................................7
Clipos™ Nanoliposomal Curcumin ......................................................................................8
Clipos™ Nanoliposomal Alpha Lipoic Acid ........................................................................9
Clipos™ Nanoliposomal Vitamins ........................................................................................10
Clipos™ Nanoliposomal Coenzyme Q10 ...........................................................................11
Clipos™ Nanoliposomal Azelaic Acid .................................................................................12
Clipos™ Nanoliposomal Soy Isoflavone ............................................................................13
Clipos™ Nanoliposomal Phenylethyl Resorcinol .............................................................14
Clipos™ Nanoliposomal Vitamin E .....................................................................................15
Clipos™ Nanoliposomal Ferulic Acid .................................................................................16
Clipos™ Nanoliposomal Phytosterol ..................................................................................17
Clipos™ Nanoliposomal Lutein ...........................................................................................18
Clipos™ Nanoliposomal Salicylic Acid ...............................................................................19
Clipos™ Nanoliposomal Retinaldehyde .............................................................................20
Clipos™ Nanoliposomal Sulfur ............................................................................................21
Clipos™ Nanoliposomal Ceramide .....................................................................................22

4 www.cd-bioparticles.net
Clipos™ Nanoliposomal Resveratrol
Catalog no: CDPR-0001
CAS number: 501-36-0
Clipos™ Nanoliposomal Resveratrol has a particle size of
less than 30nm and enables the resveratrol to be steadily
encapsulated in nano-carriers, greatly improving the
absorption efficiency and bioavailability. Clipos™
Nanoliposomal Resveratrol is amphiphilic and suitable for both water-soluble and
oil soluble system, allowing a wide range of uses. Resveratrol has many targets in
the skin, so it can be used as a skincare product to produce whitening, anti-
wrinkle, anti-bacteria, anti-inflammation, acne curing and anti-aging effects. It is
an emerging natural active substance with high efficiency.
Features:
• Clipos™ Nanoliposomal Resveratrol uses FDA GRAS grade materials for safety.
• Clipos™ Nanoliposomal Resveratrol is stable to heat, pH and shearing, so it is
convenient to use.
• Clipos™ Nanoliposomal Resveratrol greatly improves the stability and
bioavailability of resveratrol.
• Clipos™ Nanoliposomal Resveratrol can improve the stability of other active
matters in the product and facilitate absorption.
• Clipos™ Nanoliposomal Resveratrol is 100% water soluble and 100% oil soluble
(amphiphilic), allowing a wide range of uses.
Usage:
Add it at room temperature. You may heat it to over 40°
C to speed up the
dissolution. Recommended dosage: 1-5%. The optimum pH range of the system is
3.0-6.5, and the finished product should be protected from direct exposure to
sunlight (using opaque packaging). It is recommended to add UV absorber to day
care products.
Storage:
Keep it away from light at a temperature below 25°
C.

5
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Tetrahydrocurcumin (ultra-pure whitening element)
is a natural functional whitening ingredient
extracted from the roots of Ginger Curcuma longa.
Clipos™ Nanoliposomal THC
Thanks to its potent activity against tyrosinase, the whitening effect of this product is
better than that of arbutin; it can effectively inhibit the formation of oxygen free
radicals as well as eliminating the formed free radicals. Featured with significant
antioxidant effects, such as anti-aging of human skin, skin repair, lightening pigments,
and clearing freckles, it is widely applied in various skincare products for whitening,
freckle eliminating, and anti-oxidation. Tetrahydrocurcumin is hardly soluble in water
while easy to be oxidized and discolored, which limits its application in cosmetics.
Clipos™ Nanoliposomal THC has a particle size of less than 30nm and enables
tetrahydrocurcumin to be steadily wrapped in nano-carriers, greatly improving the
absorption efficiency and bioavailability. This overcomes the original defects and
maintains the advantages with a more convenient and wider range of uses.
Features:
• Clipos™ Nanoliposomal THC solves the problem of tetrahydrocurcumin’s tendency to
be oxidized and discolored.
• Clipos™ Nanoliposomal THC uses FDA GRAS materials for safety.
• Clipos™ Nanoliposomal THC has a good stability towards heat, pH and shearing and
is easy to use.
• Clipos™ Nanoliposomal THC greatly improves the stability and bioavailability of
tetrahydrocurcumin.
• Clipos™ Nanoliposomal THC improves the stability of other actives in the product
and promotes absorption.
• Clipos™ Nanoliposomal THC is 100% water soluble and 100% oil soluble
Usage:
C to speed up the dissolution.
Recommended dosage: 1-5%. The optimum pH range of the system is 3.0-6.5, and the
finished product should be protected from direct exposure to sunlight (using opaque
packaging). It is recommended that UV absorber should be added to day care
products.
Storage:
C.

CAS number: 79-81-2
Clipos™ Nanoliposomal Vitamin A Palmitate has a
particle size of less than 30nm and enables the
Vitamin A to be steadily encapsulated in
Clipos™ Nanoliposomal Vitamin A Palmitate
nanocarriers. Vitamin A palmitate is a vitamin A derivative and a fat-soluble
antioxidant. Clipos™ Nanoliposomal Vitamin A Palmitate is water-soluble,
transparent, highly effective and non-irritating vitamin A, which can repair cells
and protect against UV-induced skin aging, promote the metabolism of epidermis
and keratinocytes, and facilitate and strengthen the exfoliation of keratinocytes
and the growth of new cells, as well as the production of collagen and elastic
fibers, while helping to maintain the normal metabolic cycle of cells.
Features:
• Clipos™ Nanoliposomal Vitamin A Palmitate uses FDA GRAS grade materials for
safety.
• Clipos™ Nanoliposomal Vitamin A Palmitate is stable to heat, pH and shearing,
so it is convenient to use.
• Clipos™ Nanoliposomal Vitamin A Palmitate is 100% water soluble and 100% oil
soluble (amphiphilic), allowing a wide range of uses.
• Clipos™ Nanoliposomal Vitamin A Palmitate greatly improves the stability and
bioavailability of vitamin A.
Usage:
C to speed up the
dissolution. Recommended dosage: 1-5%. Metal ions such as iron ions must be
avoided in the system. Better effect with products such as vitamin C and vitamin E.
Storage:
C.

7
CAS number: 50-81-7
Clipos™ Nanoliposomal Vitamin C has a particle size of less
than 30nm and enables the Vitamin C to be steadily
Clipos™ Nanoliposomal Vitamin C
Nanoliposomal Vitamin C is amphiphilic and suitable for both water-soluble and oil
soluble system, allowing a wide range of uses. Vitamin C is an important antioxidant,
involved in multiple reactions in vivo which has functions such as promoting collagen
production, blocking melanin synthesis, scavenging free radicals, and preventing skin
aging.
Features:
• Clipos™ Nanoliposomal Vitamin C is a non-chemically modified stable L-C nano
product that works directly and efficiently without the need of vivo transformation.
• Clipos™ Nanoliposomal Vitamin C uses GRAS (Recognized Safety) grade materials
for safety and non-irritation.
• Clipos™ Nanoliposomal Vitamin C is 100% water soluble and 100% oil soluble
• Clipos™ Nanoliposomal Vitamin C greatly improves the stability and bioavailability
of vitamin C.
• Clipos™ Nanoliposomal Vitamin C is stable to heat, pH and shearing, so it is
convenient to use.
Usage:
Add it at ordinary temperature. You may heat it to over 40°
C to speed up the
dissolution. Recommended dosage: 1-5%. Better effect with products containing
vitamin E and ferulic acid.
Storage:
C.

Clipos™ Nanoliposomal Curcumin has a particle size of
less than 30nm and enables the curcumin to be steadily
Clipos™ Nanoliposomal Curcumin
Nanoliposomal Curcumin is amphiphilic and suitable for both water-soluble and
oil soluble system, allowing a wide range of uses. Curcumin has a variety of
biological activities, such as anti-oxidation, anti-infection, anti-inflammatory,
anti-coagulation, anti-atherosclerosis and inhibition of tumor growth. The
application of curcumin in skincare products has been widely recognized, and
has been increasingly applied to whitening, anti-allergy,anti-inflammatory and
other products.
Features:
• Clipos™ Nanoliposomal Curcumin uses FDA GRAS grade materials for safety.
• Clipos™ Nanoliposomal Curcumin is stable to heat, pH and cuts, so it is
convenient to use.
• Clipos™ Nanoliposomal Curcumin greatly improves the stability and
bioavailability of nano-curcumin.
• Clipos™ Nanoliposomal Curcumin improves the stability and absorption of
other actives in the product.
• Clipos™ Nanoliposomal Curcumin is 100% water soluble and 100% oil
soluble (amphiphilic).
Usage:
Add it at room temperature. You may heat to above 40°
C to speed up
dissolution rate. Recommended dosage: 1-5%.
Storage:
C.

9
CAS number: 62-46-4
Clipos™ Nanoliposomal Alpha Lipoic Acid has a particle
size of less than 30nm and enables the alpha lipoic acid
to be steadily encapsulated in nano-carriers, greatly
improving the absorption efficiency and bioavailability.
Clipos™ Nanoliposomal Alpha Lipoic Acid
Clipos™ Nanoliposomal Alpha Lipoic Acid is amphiphilic and suitable for both
water-soluble and oil soluble system, allowing a wide range of uses. Alpha lipoic
acid is an enzyme existing in mitochondria. Lipoic acid is effective in removing dark
eye circles, wrinkles and spots. In addition, it enhances metabolism, improving the
body’s blood circulation, so that the skin will no longer be dull and the appearance
or pores will be minimized, making your skin enviously firm and delicate.
Features:
• Clipos™ Nanoliposomal Alpha Lipoic Acid uses FDA GRAS grade materials for
safety.
• Clipos™ Nanoliposomal Alpha Lipoic Acid has good heat, pH and shear stability
and is easy to use.
• Clipos™ Nanoliposomal Alpha Lipoic Acid greatly improves ALA's stability and
bioavailability.
• Clipos™ Nanoliposomal Alpha Lipoic Acid improves the stability and absorption
of other actives in the product.
• Clipos™ Nanoliposomal Alpha Lipoic Acid is 100% water soluble and 100% oil
soluble (amphiphilic) for a wide range of applications.
Usage:
Add it at room temperature. You may heat it to above 40°
C to speed up its
dissolution, Recommended dosage: 1-3%. Better effect with products containing
lipoic acid.
Storage:
C.

CAS number: 79-81-2, 127-47-9, 10191-41-0
Clipos™ Nanoliposomal Vitamin A, E & K is a new multivitamin nanoliposome
preparation, designed for anti-aging, eye bags and dark circles. Vitamin A can
guarantee the normal state of skin tissue and maintain the normal regeneration of
basal cells. Vitamin E is a highly effective antioxidant that protects cell activity.
Menaquinone (Vitamin K2) can control blood clotting and significantly reduce the
congestion of capillaries in the lower part of the eye. The nano-multivitamin has
little incompatibility, with a structure that can be easily combined with water
molecules, showing unique advantages in the formulation.
Features:
• Clipos™ Nanoliposomal Vitamins is safe, non-toxic, non-irritating and
biodegradable.
• Clipos™ Nanoliposomal Vitamins does not contain any preservative system.
Usage:
Add at room temperature, and heating to above 40°
C can speed up the dissolution
rate. Recommended dosage: 1-5%. Better effects with Nanoliposomal Coenzyme
Q10, Nanoliposomal Azelaic Acid, etc.
Storage:
Recommended to store at 2-8°
C
Clipos™ Nanoliposomal Vitamins

Clipos™ Nanoliposomal Coenzyme Q10 has a particle size of less
than 30nm and enables the coenzyme Q10 to be steadily
encapsulated in nano-carriers, greatly improving the absorption
efficiency and bioavailability. Coenzyme Q10 has stronger
antioxidant function, and it can effectively eliminate free radicals
and has good anti-aging, anti-wrinkle and whitening functions.
Clipos™ Nanoliposomal Coenzyme Q10
11
Features:
• Clipos™ Nanoliposomal Coenzyme Q10 uses FDA GRAS grade materials for
safety.
• Clipos™ Nanoliposomal Coenzyme Q10 has good heat, pH and sheer stability
and is easy to use.
• Clipos™ Nanoliposomal Coenzyme Q10 greatly improves the stability and
bioavailability of CoQ10.
• Clipos™ Nanoliposomal Coenzyme Q10 can improve the stability of other active
• Clipos™ Nanoliposomal Coenzyme Q10 is 100% water soluble and 100% oil
soluble (amphiphilic), allowing a wide range of uses.
Usage:
Add it at ordinary temperature. Heat it to over 40°
Recommended dosage: 1-5%. Better effect with products containing lipoic acid.
Storage:
C.

Clipos™ Nanoliposomal Azelaic Acid has a particle
size of less than 30nm and enables the azelaic
acid to be steadily encapsulated in nano-carriers,
Clipos™ Nanoliposomal Azelaic Acid
Features:
• Clipos™ Nanoliposomal Azelaic Acid uses FDA GRAS materials for safety.
• Clipos™ Nanoliposomal Azelaic Acid is stable to heat, pH and shearing, so it is
convenient to use.
• Clipos™ Nanoliposomal Azelaic Acid overcomes the original shortcomings of
azelaic acid while maintaining the advantages and improving bioavailability.
• Clipos™ Nanoliposomal Azelaic Acid improves the stability of other actives in the
product and facilitates absorption.
Usage:
It allows a wide range of applications, and can be used in various systems such as
freshener, essence, cream, and lotions. Add it at room temperature. You may heat it
to over 40°
C to speed up the dissolution. Recommended dosage: 1-5%.
Storage:
C.
greatly improving the absorption efficiency and bioavailability. It is a good solution
to the deficiency of azelaic acid while maintaining the original advantages. It has
good compatibility and is very effective in regulating the normal secretion of sebum,
eliminating acne and whitening skin. Azelex, known as azelaic acid, is a natural
saturated dicarboxylic acid containing nine carbon atoms and is an important
medium-long chain dibasic acid, featured with the effect of inhibiting excessive
secretion of grease, eliminating acne and skin whitening, as well as high security.

Clipos™ Nanoliposomal Soy Isoflavone has a particle size of less
than 30nm and enables the soy isoflavones to be steadily
encapsulated in nano-carriers, greatly improving the absorption
efficiency and bioavailability. Nanoliposomal is water-soluble even
when it contains an oil-soluble active substance such as soy
isoflavone. The solution is completely clear and transparent, so the
product is applicable to clear hydrogel formulations.
Clipos™ Nanoliposomal Soy Isoflavone
13
Features:
• Shearing stability
• pH stability
• Heat stability
• Improvement on skin texture
• Low viscosity
Usage:
Recommended dosage: 1% – 3%
Storage:
Store with its original packaging at room temperature (<25°
C).

CAS number: 85-27-8
Clipos™ Nanoliposomal Phenylethyl Resorcinol has a
particle size of less than 30nm and enables the
phenylethyl resorcinol to be steadily encapsulated in
nano-carriers, greatly improving the absorption
efficiency and bioavailability. Clipos™ Nanoliposomal
Clipos™ Nanoliposomal Phenylethyl Resorcinol
Features:
• Clipos™ Nanoliposomal Phenylethyl Resorcinol uses FDA GRAS grade materials
for safety.
• Clipos™ Nanoliposomal Phenylethyl Resorcinol greatly improves the stability and
bioavailability.
• Clipos™ Nanoliposomal Phenylethyl Resorcinol can improve the stability of other
active matters in the product and facilitate absorption.
Usage:
Add it at room temperature. Heat it to above 40°
Recommended dosage: 0.1-5%. The optimum pH range of the system is 3.0-6.5,
and the finished product should be protected from direct sunlight (using opaque
packaging). It is recommended to add UV absorber to day care products.
Storage:
C.
Phenylethyl Resorcinol is amphiphilic and suitable for both water-soluble and oil
soluble system, allowing a wide range of uses. Phenylethyl resorcinol is a new high-
efficiency skin whitening agent derived from silver pine. It is clinically proven that its
whitening ability is equivalent to that of hydroquinone, approved by various
countries and gradually used in cosmetics.

CAS number: 10191-41-0, 7695-91-2, 59-02-9
Clipos™ Nanoliposomal Vitamin E has a particle
size of less than 30nm and enables the vitamin E
to be steadily encapsulated in nano-carriers,
Clipos™ Nanoliposomal Vitamin E
15
Features:
• Clipos™ Nanoliposomal Vitamin E is 100% water soluble and 100% oil soluble
(amphiphilic) for a wide range of application.
• Clipos™ Nanoliposomal Vitamin E greatly improves the stability and bioavailability
of vitamin E.
• Clipos™ Nanoliposomal Vitamin E has good heat, pH and shear stability and is
easy to use.
• Clipos™ Nanoliposomal Vitamin E is rich in active substances, which can be up to
20%.
• Clipos™ Nanoliposomal Vitamin E uses FDA GRAS grade materials for safety.
• Clipos™ Nanoliposomal Vitamin E can increase the amount of vitamin E infiltrated
into the depth of the epidermis while traditional oil-in-water emulsion loose
vitamin E can only stay on the skin surface.
Usage:
C to speed up the
dissolution. Recommended dosage: 1-5%. Better effect with products containing
Nanoliposomal Coenzyme Q10.
Storage:
Recommended to store it at 2-8°
C
greatly improving the absorption efficiency and bioavailability. Clipos™
Nanoliposomal Vitamin E is amphiphilic and suitable for both water-soluble and oil
soluble system, allowing a wide range of uses. Vitamin E can reduce the aging of
tissue cells and the production of streak tissue, improve the effect of vitamin A,
and prevent the oxidation of vitamin A and vitamin C. The external use of vitamin E
has been proven to be effective in supplying vitamin E to the skin.

Clipos™ Nanoliposomal Ferulic Acid has a particle size
of less than 30nm and enables the ferulic acid to be
steadily encapsulated in nano-carriers, greatly
Clipos™ Nanoliposomal Vitamin E is amphiphilic and
suitable for both water-soluble and oil soluble system,
Clipos™ Nanoliposomal Ferulic Acid
Features:
• Clipos™ Nanoliposomal Ferulic Acid uses FDA GRAS (Generally Recognized as
Safe) materials so it is safe.
• Clipos™ Nanoliposomal Ferulic Acid has a good stability towards heat, pH and
shearing, so it is easy to use.
• Clipos™ Nanoliposomal Ferulic Acid greatly improves the stability and
bioavailability of ferulic acid.
• Clipos™ Nanoliposomal Ferulic Acid improves the stability and absorption of
other actives in the product.
• Clipos™ Nanoliposomal Ferulic Acid is 100% water soluble and 100% oil soluble
Usage:
Add this product at room temperature and heat it to above 40°
C to speed up its
dissolution. Recommended dosage: 1-5%. It works better with products such as
Nanoliposomal Vitamin C and E.
Storage:
C.
allowing a wide range of uses. Ferulic acid is an intercellular adhesive that binds the
polysaccharides among cells to make the skin firm and elastic. It is effective in
eliminating free radicals, anti-thrombus, anti-bacteria, anti-inflammation, inhibiting
tumor, preventing hypertension, and heart diseases, enhancing the vitality of sperm
as well as other health functions and protecting the skin.

Clipos™ Nanoliposomal Phytosterol has a particle
size of less than 30nm and enables the phytosterol
to be steadily encapsulated in nano-carriers,
Clipos™ Nanoliposomal Phytosterol
17
Usage:
C to speed up its
dissolution; recommended dosage: 1-5%. It works better with products such as
Nanoliposomal Vitamin A Palmitate and Nanoliposomal Ceramides.
Storage:
C.
greatly improving the absorption efficiency and bioavailability. Clipos™
Nanoliposomal Phytosterol is amphiphilic and suitable for both water-soluble and
oil soluble system, allowing a wide range of uses. Phytosterol is a kind of natural
physiologically active substances beneficial to humans. It can inhibit the cholesterol
absorption of humans, promote the degradation and metabolism of cholesterol,
inhibit the biosynthesis of cholesterol, etc., and has been found to have the
function of inhibiting cardiovascular diseases in animal studies. Also, it is effective
in anti-cancer, anti-tumor, anti-inflammatory, improving immunity, regulating
growth, anti-virus, anti-oxidation, etc.

Clipos™ Nanoliposomal Lutein has a particle size of
less than 30nm and enables the lutein to be steadily
Clipos™ Nanoliposomal Lutein
Features:
• Clipos™ Nanoliposomal Lutein uses FDA GRAS grade materials for safety.
• Clipos™ Nanoliposomal Lutein is stable to heat, pH, and cuts, so it is convenient
to use.
• Clipos™ Nanoliposomal Lutein greatly enhances the stability and bioavailability
of lutein.
• Clipos™ Nanoliposomal Lutein improves the stability and absorption of other
actives in the product.
• Clipos™ Nanoliposomal Lutein is 100% water soluble and has a wide range of
applications.
Usage:
Add under low temperature; recommended dosage: 1-5%.
Storage:
Keep away from light at a temperature below 25°
C.
Nanoliposomal Lutein is amphiphilic and suitable for both water-soluble and oil
soluble system, allowing a wide range of uses. Lutein is a good antioxidant that
protects cells in human body from the damage of free radical. Lutein is good for
vision health as it can resist sunlight, blue light in computer and cellphone screens,
relieve eye fatigue, sore eyes, tears, myopia, and prevent eye diseases such as
cataracts and maculopathy. Lutein also plays a role in filtering blue light and strong
anti-oxidation for the skin, greatly avoiding the damage of light to skin cells and
preventing various kinds of skin disease caused by intense light stimulation.

CAS number: 69-72-7
Clipos™ Nanoliposomal Salicylic Acid has a particle size
of less than 30nm and enables the salicylic acid to be
Clipos™ Nanoliposomal Salicylic Acid is amphiphilic
Clipos™ Nanoliposomal Salicylic Acid
19
Features:
• Clipos™ Nanoliposomal Salicylic Acid uses FDA GRAS grade materials for safety.
• Clipos™ Nanoliposomal Salicylic Acid is stable to heat, pH and shearing, so it is
convenient to use.
• Clipos™ Nanoliposomal Salicylic Acid overcomes the original shortcomings of
salicylic acid while maintaining the advantages and improves bioavailability.
• Clipos™ Nanoliposomal Salicylic Acid can improve the stability of other active
Usage:
C to speed up the
dissolution. Recommended dosage: 1-5%. Divalent or trivalent metal ions such as
iron must be avoided in the system.
Storage:
C.
and suitable for both water-soluble and oil soluble system, allowing a wide range
of uses. Salicylic acid has an excellent ability to clear acne, exfoliate, and clean
pores with safety. Salicylic acid can also lighten pigment spots, shrink pores,
remove fine wrinkles, and improve aging caused by sun exposure, thus becoming
the new favor of skincare products.

Clipos™ Nanoliposomal Retinaldehyde has a particle
size of less than 30nm and enables the retinaldehyde
to be steadily encapsulated in nano-carriers, greatly
Clipos™ Nanoliposomal Retinaldehyde
Features:
• Clipos™ Nanoliposomal Retinaldehyde uses FDA GRAS grade materials for safety.
• Clipos™ Nanoliposomal Retinaldehyde has good heat, pH and sheer stability and
is easy to use.
• Clipos™ Nanoliposomal Retinaldehyde greatly enhances the stability and
bioavailability of retinal.
• Clipos™ Nanoliposomal Retinaldehyde can improve the stability of other active
• Clipos™ Nanoliposomal Retinaldehyde is 100% water soluble and 100% oil
soluble, allowing a wide range of uses.
Usage:
Add it at room temperature; recommended dosage: 1-5%. The optimum pH range
of the system is 3.0-6.5, and the finished product should avoid direct exposure to
sunlight (using opaque packaging). It is recommended to add UV absorber to day
care products.
Storage:
C.
Clipos™ Nanoliposomal Retinaldehyde is amphiphilic and suitable for both water-
soluble and oil soluble system, allowing a wide range of uses. Retinaldehyde (RAL),
also known as vitamin A aldehyde, is a derivative of retinol after oxidation. It can be
used as a skin care product to produce a variety of effects such as anti-aging, skin
rejuvenation, whitening, anti-wrinkle, acne, and keratin. It is an emerging high-
efficiency natural active substance.

Clipos™ Nanoliposomal Sulfur with a particle size of less than
30 nm developed by Nano-transport system (NDS) has
completely solved sulfur’s solubility problem, allowing it to be
stably encapsulated in a nanocarrier, which can greatly increase
its absorption efficiency and bioavailability. Sulfur has long
Clipos™ Nanoliposomal Sulfur
21
Features
• Clipos™ Nanoliposomal Sulfur uses FDA GRAS grade materials for safety.
• Clipos™ Nanoliposomal Sulfur has good heat, pH and shear stability and is easy
to use.
• Clipos™ Nanoliposomal Sulfur improves the stability and absorption of other
actives in the product.
• Clipos™ Nanoliposomal Sulfur is 100% water soluble and 100% oil soluble
(amphiphilic) for a wide range of applications.
Usage:
Add at room temperature, heat it to above 40°
C to speed up its dissolution.
Recommended dosage: 1-3%. Better effect with products containing lipoic acid.
Storage:
Keep it below 25°
C and away from light.
been an effective drug for the treatment of various skin diseases. Sulfur is a sebum
regulating agent that has triple effects on problem skin, namely antibacterial, anti-
inflammatory and sebum regulating. Water-soluble and non-irritating to the skin, in
cosmetics, it can regulate the secretion function of sebaceous glands, and facilitate
skin whitening. It is also effective in anti-bacteria, reducing the appearance of
whelk, acne and dandruff.

CAS number: 100403-19-8
Clipos™ Nanoliposomal Ceramide has a particle size of
less than 30nm and enables the ceramide to be
Clipos™ Nanoliposomal Ceramide
Usage:
Add it at an ordinary temperature; recommended dosage: 5-10%. Better effect with
products such as yeast glucan liposome.
Storage:
C.
improving the absorption efficiency and bioavailability. Clipos™ Nanoliposomal
Ceramide is amphiphilic and suitable for both water-soluble and oil soluble system,
allowing a wide range of uses. Ceramide is the most important component of the
lipid barrier of the skin, and ceramide can repair the skin barrier function. The
application of a skincare product containing ceramide for external use can achieve
the purpose of preventing allergic skin diseases and the effect of suppressing
melanin brown spots.

Phone:1-631-624-4882 Fax:1-631-938-8221 E-mail: info@cd-bioparticles.com
45-1 Ramsey Road, Shirley, NY 11967, USA
Contact Us

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