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Stem Cell Research – India 
Stem Cell Research India
July 2012
Executive Summary
              • The Stem Cell Therapy market in India was valued at INR x1 units in 20‐‐ which is expected to 
               reach INR x2 units approximately by 20‐‐
              • The Stem Cell Banking Market was worth INR y1 units in 20‐‐ and is expected to reach INR y2
  Market        units  in 20‐‐
              • India is projected to see a rise in number of stem cell bank and stem cell depositors in near
                India is projected to see a rise in number of stem cell bank and stem cell depositors in near           
                future
              Drivers:                                                   Challenges:
                •Favorable Regulatory Environment
                                                                           • High Cost of Therapy
                                                                             High Cost of Therapy
                •High Patient Population
                                                                           • Capital intensive nature of research is 
 Drivers &      •Application in Drug Development
                                                                             decelerating the market
Challenges      •Increasing Awareness
                                                                           • ‘Development Costs’ of Stem Cell 
                •Growing Medical Tourism
                                                                             resulting in slow progress of the market 
                •Increasing Health Expenditure
                •Increasing Health Expenditure

                                                                       • Efforts to increase awareness in stem cell
              •Increasing partnerships
  Trends      •Increasing investments
                                                                       • Easy financing opportunities in stem cell 
                                                                         banking

                                                              Major Players
                       Stem Cell Banks              Company A, Company B, Company C, Company D, Company E, Company F
Competition                                         Organization A, Organization B, Organization C, Organization D, 
                                                    Organization A Organization B Organization C Organization D
               Stem Cell Research Organizations
                                                    Organization E, Organization F, Organization G, Organization H


                                  STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                                           2
•Introduction
•Market Overview
•Drivers & Challenges
•Value Chain
•Market Trends
 M k tT d
•Potential Stem Cell Sources
•Competition
   Stem Cell Banks
   Research Organizations
    Research Organizations
•Recent Developments
•Strategic Recommendations
       g
•Appendix
       STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT   3
Stem cell banking and therapeutic application are the two 
key area of concern which are bridged by stem cell research
  Stem Cell can be the solution to a myriad of diseases like Parkinson's disease, amyotrophic lateral sclerosis, spinal 
  cord injury, burns, heart disease, diabetes and arthritis and also for neurological problems like autism and cerebral 
                     palsy and is also becoming an important tool for testing potential drug toxicity

                    Stem Cell Therapy                                                        Stem Cell Banking

                                                                   • It is a concept of preserving the stem cells for specific 
• It is an emerging therapy wherein a damaged tissue                 future therapeutic uses
  that cannot heal itself is repaired by the use of stem cell      • The extraction of cord blood stem cells take about 10–15 
• Stem cells are the unspecialized blood cell that has the           minutes and is applicable to both normal and caesarean 
  capacity to replicate and produce its own blood cells,             deliveries
  platelets, red and white blood cells                             • The cells can be cryo‐frozen and kept stored for decades in 
• The “Cord Blood” is a rich source of stem cells and a 
  The  Cord Blood is a rich source of stem cells and a               liquid nitrogen
                                                                     liquid nitrogen
  critical input for such surgical treatments                      • Cord blood is more like a ‘biological future health 
                                                                     insurance’ for the newborn baby and its future offspring’s 
                                                                     and siblings

                                                                              Public Banks                       Private Banks

                                                                    •Use not restricted               •For use of family only
                                                                    •No remuneration collected        •Facility paid for by family
                                                                    •Usage subject to availability    •Availability guaranteed

The benefits of stem cell is manifold as the cell’s usage is not just restricted to the child but siblings or family members 
                               can use the cells if required, after a tissue matching is done

                                             STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                                            4
Stem cell therapy market is poised to grow at a very high 
rate due to increasing therapeutic applications
Stem Cell Therapy Market – Overview                                     Market Size and Growth
• The Stem Cell Therapy market in India was valued at                  INR units
  INR x1 units in 20‐‐
                                                                       80
• The market is expected to reach INR x6 units                                                                                   x6
                                                                                                         X%
  approximately by 20‐‐, growing at a CAGR of X% for                   60                                                x5
                                                                                                                 x4
  this time period                                                                               x2
                                                                                                         x3
                                                                       40                  x1
• The stem cell research is a key factor that propels the                      x0
  therapeutic market                                                   20
• Almost m stem cell transplants are carried out in                      0
  India annually that is growing gradually                                    20‐‐     20‐‐     20‐‐e   20‐‐e   20‐‐e   20‐‐e   20‐‐e


Stem Cell Banking Market – Overview 
Stem Cell Banking Market Overview                                       Market Size and Growth
                                                                        Market Size and Growth
• The Stem Cell Banking Market was worth INR y1                        INR units
  units in 20‐‐ and is expected to reach INR y6 units in               10                                                        y6
  20‐‐
                                                                        8
• The stem cell b k
    h          ll banking market is expected to exhibit a
                             k             d      hb                                                     Y%              y5
  CAGR of Y% between 20‐‐ and 20‐‐                                      6                                        y4
• Stem cell banking that was unheard of a few years                     4                                y3
  back but has become popular in the recent past as a                                            y2
                                                                                           y1
                                                                        2      y0
  less traumatic alternative to treat neurological
  diseases and as guarantee for the entire family                       0
  against several other diseases                                              20‐‐     20‐‐     20‐‐e   20‐‐e   20‐‐e   20‐‐e   20‐‐e

                                            STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                                              5
Drivers & Challenges – Summary 



  Drivers
    i

  Favorable Regulatory Environment
                                                                      Challenges
  High Patient Population
                                                                      High Cost of Therapy

  Application in Drug Development
                                                                      Capital Intensive Market

  Increasing Awareness                                                High Development Cost

  Growing Medical Tourism

  Increasing R&D Expenditure




                                     STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                6
Trends – Summary 




         Easy financing opportunities in 
                                                         Increasing Partnerships
                stem cell banking


                                             Key 
                                            Trends

         Efforts to increase awareness 
                                                          Increasing Investments
                   in stem cell




                           STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT            7
Private: Foreign Company – Company A (1/3) 
Company Information                                                           Offices and Centres – India 
                        Company A
                        Street A
Corporate Address
                        City B
                        City B
                        State C
                                                                                          City B
Tel No.                 +91 124 7239

Fax No.
Fax No                  +91 124 4734111
                        +91 124 4734111
Website                 www.CompanyAcom
Year of Incorporation   2005


Products and Services
P d t      dS i                                                                                                 Head Office

Category                Products/Services
                        Engages in collection, isolation and                  Key People
Stem cell banking 
                        storage of cord blood stem cells
                                                                              Name                       Designation
                                                                              Person A                   Chairman
                                                                              Person B                   Managing Director
                                                                              Person C
                                                                              Person C                   CEO




                                                  STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                                8
Private: Foreign Company – Company A (2/3) 
Financial Snapshot
 i    i lS     h                                                            Key Ratios
                                                                            K      i
                                                                                                             y‐o‐y change 
                    Total Income      Net Profit/Loss                                  Particulars 
                                                                                                               (2011‐10)
                                                                                                                           2011   2010   2009     2008

 INR units                                                 INR units         Profitability Ratios
                                                                              Operating Margin
250                                                                ‐20
                                                                    20
                                                                              Net Margin
200           a                                                               Profit Before Tax Margin
                                                                   ‐40        Return on Equity
150                                                  d
                            b          c             R4                       Return on Capital Employed
100                                    R3                                     Return on Working Capital
                                                                   ‐60
 50                         R2                                                Return on Assets
             R1                                                               Return on Fixed Assets
  0                                                                ‐80       Cost Ratios
             20‐‐          20‐‐       20‐‐          20‐‐                      Operating costs (% of Sales)
                                                                              Administration costs (% of 
                                                                                Sales)
Financial Summary                                                             Interest costs (% of Sales)
                                                                              Interest costs (% of Sales)
• The company incurred a net loss of INR d units in FY 20‐‐, as              Liquidity Ratios
                                                                              Current Ratio
  compared to net loss of INR c units in FY 20‐‐
                                                                              Cash Ratio
• The company reported total income of INR R4 units in FY 20‐‐,              Leverage Ratios
  registering an increase of m% over FY 20‐‐                                  Debt to Equity Ratio
                                                                              Debt to Capital Ratio
                                                                                 b        i l    i
• The company earned an operating margin of f% in FY 20‐‐, an                 Interest Coverage Ratio
  increase of g percentage points over FY 20‐‐                               Efficiency Ratios
• The company reported debt to equity ratio of d in FY 20‐‐, a                Fixed Asset Turnover
  decrease of h% over FY 20‐‐                                                 Asset Turnover
                                                                              Current Asset Turnover
                                                                              Working Capital Turnover
                                                                              Capital Employed Turnover
                                                                                                                                  Improved      Decline

                                                   STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                                                       9
Private: Foreign Company – Company A (3/3) 
Business Highlights

Description           News


Overview              • It was formed as a joint venture between Company A and Company B




Stem Cell Banking     • It provides collection facility from all major cities in India




                      • The company was awarded the most prestigious American Association of Blood Banks  
Recognitions            (AABB) Accreditation




                                    STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                             10
Appendix

Ratio                          Calculations                              Ratio                        Calculations
                               (Operating                                                             Current Assets / Current 
Operating Margin                                                         Current Ratio
                               Income/Revenues)*100                                                   Liabilities 

Net Margin                     (Net Profit / Revenues) *100                                           {(Cash & Bank Balance + 
                                                                         Cash Ratio                   Marketable Securities) / Current 
                               (Income Before Tax / Revenues                                          Liabilities)} 
Profit Before Tax Margin
                               *100 
                                                                                                      Total Liabilities / Shareholders 
                                                                                  q y
                                                                         Debt to Equity 
                               (Net Income / Shareholders 
                               (N I         / Sh h ld                                                 Equity 
                                                                                                      E it
Return on Equity (ROE) 
                               Equity)*100 
                                                                                                      {Total Debt / (Shareholders 
                                                                         Debt to Capital Ratio
                               EBIT / (Total Assets – Current                                         Equity + Total Debt)} 
Return on Capital (ROCE) 
                               Liabilities)*100 
                                                                         Interest Coverage Ratio      EBIT / Interest Expense
                               (Net Income / Working Capital) 
                               (N I        / W ki C i l)
Return on Working Capital
                               *100
                                                                         Fixed Asset Turnover         Sales / Fixed Assets 
Return on Assets               (Net Income / Total Assets)*100 
                                                                         Asset Turnover               Sales / Total Assets 
Return on Fixed Assets         (Net Income / Fixed Assets) *100 

                               (Operating Expenses / Sales)              Current Asset Turnover       Sales / Current Assets 
Operating Costs (% of Sales)
                               *100 

Administration Costs (% of     (Administrative Expenses / Sales)         Working Capital Turnover     Sales / Working Capital 
Sales)                         *100 

Interest Costs (% of Sales)    (Interest Expenses / Sales) *100          Capital Employed Turnover    Sales / Shareholders Equity 
                                                                                                            /



                                               STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                                          11
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Disclaimer: This report is published for general information only Although high standards have been used in the preparation “Netscribes” is 
not responsible for any loss or damage arising from use of this document. This document is the sole property of Netscribes and prior 
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                                                  STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT                                             12

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Market Research Report : Stem Cell Research Marklet in India 2012

  • 1. Insert Cover Image using Slide Master View Do not distort Stem Cell Research – India  Stem Cell Research India July 2012
  • 2. Executive Summary • The Stem Cell Therapy market in India was valued at INR x1 units in 20‐‐ which is expected to  reach INR x2 units approximately by 20‐‐ • The Stem Cell Banking Market was worth INR y1 units in 20‐‐ and is expected to reach INR y2 Market units  in 20‐‐ • India is projected to see a rise in number of stem cell bank and stem cell depositors in near India is projected to see a rise in number of stem cell bank and stem cell depositors in near            future Drivers: Challenges: •Favorable Regulatory Environment • High Cost of Therapy High Cost of Therapy •High Patient Population • Capital intensive nature of research is  Drivers &  •Application in Drug Development decelerating the market Challenges •Increasing Awareness • ‘Development Costs’ of Stem Cell  •Growing Medical Tourism resulting in slow progress of the market  •Increasing Health Expenditure •Increasing Health Expenditure • Efforts to increase awareness in stem cell •Increasing partnerships Trends •Increasing investments • Easy financing opportunities in stem cell  banking Major Players Stem Cell Banks Company A, Company B, Company C, Company D, Company E, Company F Competition Organization A, Organization B, Organization C, Organization D,  Organization A Organization B Organization C Organization D Stem Cell Research Organizations Organization E, Organization F, Organization G, Organization H STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 2
  • 3. •Introduction •Market Overview •Drivers & Challenges •Value Chain •Market Trends M k tT d •Potential Stem Cell Sources •Competition  Stem Cell Banks  Research Organizations Research Organizations •Recent Developments •Strategic Recommendations g •Appendix STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 3
  • 4. Stem cell banking and therapeutic application are the two  key area of concern which are bridged by stem cell research Stem Cell can be the solution to a myriad of diseases like Parkinson's disease, amyotrophic lateral sclerosis, spinal  cord injury, burns, heart disease, diabetes and arthritis and also for neurological problems like autism and cerebral  palsy and is also becoming an important tool for testing potential drug toxicity Stem Cell Therapy Stem Cell Banking • It is a concept of preserving the stem cells for specific  • It is an emerging therapy wherein a damaged tissue  future therapeutic uses that cannot heal itself is repaired by the use of stem cell • The extraction of cord blood stem cells take about 10–15  • Stem cells are the unspecialized blood cell that has the  minutes and is applicable to both normal and caesarean  capacity to replicate and produce its own blood cells,  deliveries platelets, red and white blood cells • The cells can be cryo‐frozen and kept stored for decades in  • The “Cord Blood” is a rich source of stem cells and a  The  Cord Blood is a rich source of stem cells and a liquid nitrogen liquid nitrogen critical input for such surgical treatments • Cord blood is more like a ‘biological future health  insurance’ for the newborn baby and its future offspring’s  and siblings Public Banks Private Banks •Use not restricted •For use of family only •No remuneration collected •Facility paid for by family •Usage subject to availability •Availability guaranteed The benefits of stem cell is manifold as the cell’s usage is not just restricted to the child but siblings or family members  can use the cells if required, after a tissue matching is done STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 4
  • 5. Stem cell therapy market is poised to grow at a very high  rate due to increasing therapeutic applications Stem Cell Therapy Market – Overview  Market Size and Growth • The Stem Cell Therapy market in India was valued at INR units INR x1 units in 20‐‐ 80 • The market is expected to reach INR x6 units x6 X% approximately by 20‐‐, growing at a CAGR of X% for 60 x5 x4 this time period x2 x3 40 x1 • The stem cell research is a key factor that propels the x0 therapeutic market 20 • Almost m stem cell transplants are carried out in 0 India annually that is growing gradually 20‐‐ 20‐‐ 20‐‐e 20‐‐e 20‐‐e 20‐‐e 20‐‐e Stem Cell Banking Market – Overview  Stem Cell Banking Market Overview Market Size and Growth Market Size and Growth • The Stem Cell Banking Market was worth INR y1 INR units units in 20‐‐ and is expected to reach INR y6 units in 10 y6 20‐‐ 8 • The stem cell b k h ll banking market is expected to exhibit a k d hb Y% y5 CAGR of Y% between 20‐‐ and 20‐‐ 6 y4 • Stem cell banking that was unheard of a few years 4 y3 back but has become popular in the recent past as a y2 y1 2 y0 less traumatic alternative to treat neurological diseases and as guarantee for the entire family 0 against several other diseases 20‐‐ 20‐‐ 20‐‐e 20‐‐e 20‐‐e 20‐‐e 20‐‐e STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 5
  • 6. Drivers & Challenges – Summary  Drivers i Favorable Regulatory Environment Challenges High Patient Population High Cost of Therapy Application in Drug Development Capital Intensive Market Increasing Awareness High Development Cost Growing Medical Tourism Increasing R&D Expenditure STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 6
  • 7. Trends – Summary  Easy financing opportunities in  Increasing Partnerships stem cell banking Key  Trends Efforts to increase awareness  Increasing Investments in stem cell STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 7
  • 8. Private: Foreign Company – Company A (1/3)  Company Information Offices and Centres – India  Company A Street A Corporate Address City B City B State C City B Tel No. +91 124 7239 Fax No. Fax No +91 124 4734111 +91 124 4734111 Website www.CompanyAcom Year of Incorporation 2005 Products and Services P d t dS i Head Office Category Products/Services Engages in collection, isolation and  Key People Stem cell banking  storage of cord blood stem cells Name Designation Person A Chairman Person B Managing Director Person C Person C CEO STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 8
  • 9. Private: Foreign Company – Company A (2/3)  Financial Snapshot i i lS h Key Ratios K i y‐o‐y change  Total Income Net Profit/Loss Particulars  (2011‐10) 2011 2010 2009 2008 INR units INR units Profitability Ratios Operating Margin 250 ‐20 20 Net Margin 200 a Profit Before Tax Margin ‐40 Return on Equity 150 d b c R4 Return on Capital Employed 100 R3 Return on Working Capital ‐60 50 R2 Return on Assets R1 Return on Fixed Assets 0 ‐80 Cost Ratios 20‐‐ 20‐‐ 20‐‐ 20‐‐ Operating costs (% of Sales) Administration costs (% of  Sales) Financial Summary  Interest costs (% of Sales) Interest costs (% of Sales) • The company incurred a net loss of INR d units in FY 20‐‐, as  Liquidity Ratios Current Ratio compared to net loss of INR c units in FY 20‐‐ Cash Ratio • The company reported total income of INR R4 units in FY 20‐‐,  Leverage Ratios registering an increase of m% over FY 20‐‐ Debt to Equity Ratio Debt to Capital Ratio b i l i • The company earned an operating margin of f% in FY 20‐‐, an  Interest Coverage Ratio increase of g percentage points over FY 20‐‐ Efficiency Ratios • The company reported debt to equity ratio of d in FY 20‐‐, a  Fixed Asset Turnover decrease of h% over FY 20‐‐ Asset Turnover Current Asset Turnover Working Capital Turnover Capital Employed Turnover Improved Decline STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 9
  • 10. Private: Foreign Company – Company A (3/3)  Business Highlights Description  News Overview • It was formed as a joint venture between Company A and Company B Stem Cell Banking • It provides collection facility from all major cities in India • The company was awarded the most prestigious American Association of Blood Banks   Recognitions (AABB) Accreditation STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 10
  • 11. Appendix Ratio Calculations Ratio Calculations (Operating  Current Assets / Current  Operating Margin Current Ratio Income/Revenues)*100 Liabilities  Net Margin (Net Profit / Revenues) *100 {(Cash & Bank Balance +  Cash Ratio Marketable Securities) / Current  (Income Before Tax / Revenues  Liabilities)}  Profit Before Tax Margin *100  Total Liabilities / Shareholders  q y Debt to Equity  (Net Income / Shareholders  (N I / Sh h ld Equity  E it Return on Equity (ROE)  Equity)*100  {Total Debt / (Shareholders  Debt to Capital Ratio EBIT / (Total Assets – Current  Equity + Total Debt)}  Return on Capital (ROCE)  Liabilities)*100  Interest Coverage Ratio EBIT / Interest Expense (Net Income / Working Capital)  (N I / W ki C i l) Return on Working Capital *100 Fixed Asset Turnover Sales / Fixed Assets  Return on Assets (Net Income / Total Assets)*100  Asset Turnover Sales / Total Assets  Return on Fixed Assets (Net Income / Fixed Assets) *100  (Operating Expenses / Sales)  Current Asset Turnover  Sales / Current Assets  Operating Costs (% of Sales) *100  Administration Costs (% of  (Administrative Expenses / Sales)  Working Capital Turnover Sales / Working Capital  Sales) *100  Interest Costs (% of Sales) (Interest Expenses / Sales) *100  Capital Employed Turnover  Sales / Shareholders Equity  / STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 11
  • 12. Thank you for the attention The Stem Cell Research Market – India report is part of Research on India’s Healthcare Series. For more detailed information or customized research requirements please contact: Phone: +91 33 4064 6214 91 33 4064 6214 E‐Mail: sales@netscribes.com Follow us on: About Netscribes Netscribes is a knowledge‐consulting and solutions firm with clientele across the globe. The company’s expertise spans areas of investment &  g g f g p y p p f business research, business & corporate intelligence, content‐management services, and knowledge‐software services. At its core lies a true  value proposition that draws upon a vast knowledge base. Netscribes is a one‐stop shop designed to fulfil clients’ profitability and growth  objectives. Disclaimer: This report is published for general information only. Although high standards have been used in the preparation,  Netscribes is Disclaimer: This report is published for general information only Although high standards have been used in the preparation “Netscribes” is  not responsible for any loss or damage arising from use of this document. This document is the sole property of Netscribes and prior  permission is required for guidelines on reproduction. STEM CELL  RESEARCH MARKET IN INDIA 2012.PPT 12