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Cholera:
Brief Epidemiology &
Prevention
DR. Rambadan P. Chauhan
MD (PSM), ACME (MET)
Professor-Community Medicine
BKLWR Medical College- Sawarde, District-Ratnagiri
chauhanrambadan@gmail.com
5/11/2021 1
Dr Rambadan Chauhan
Lecture Objectives: (Cholera)
At the end of lecture you {student (s)}
should be able to understand,
Epidemiology of Cholera
Prevention of cholera
Cholera
Agent: Vibrio Cholerae 2 types :Classical & Eltor.
El-Tor: 3 sub types Ogawa,Hikojima & Inaba .
MCC=El Tor Hybrid
Host: All ages & sexes.
Environment: Pilgrimage, marriage, fairs &
festivals, Poor sanitation.
MOT: Feco-oral routine. Contaminated drinks &
foods
Cholera
Incubation Period: Common: 1-2 days Range: few hours to 5 days
Infective Material: Stool and vomit of cases and carriers.
Carrier types: Incubatory 1-5 days. Convalescent carriers 2-3
weeks. Contact/Healthy carriers for 10 days. Chronic Carriers from
3 months to 10 years. Reservoir-Gall bladder.
Clinical Features: Profuse painless watery diarrhea with vomiting.
Rapid severe dehydration. 3stages-Evacuation, collapse &
recovery/death.
Investigations: 1.Microscopy-Gram negative with curved rod with
characteristic scintillating type of movements. 2.Culture
3.Biochemical tests 4.Serology etc
Cholera: Primary Prevention
Primary Prevention:
1.Safe water and sanitary latrines.
2.Hand washing with soap and water.
3.Health education
Specific Protection:
Cholera vaccine: 3 months before Pilgrimage,
marriage, fairs & festivals.
3 types of oral vaccines: 1. Dukoral (WC-rBS)
2.Sanchol and mORCVAX 3. Euvichol
Dosage Schedule: initially 2/3 doses with 1 week
to 1 month interval. Boosters every 3 years.
Age: 2 years and above
Cholera:Secondary Prevention
EDAT: V NEERAC
1.Verification of diagnosis : Hanging drop & Biochemical
tests
2.Notification: Local-National & International
3.Early case finding: The users of the contaminated source
4.Establishment of treatment centres : Temporary/Regular
5.Rehydration therapy: ORS & IVT [75-100 ml/kg/day],
Rapid.
6.Antibiotics- Ciprofloxacin, Azithromycin, Tetracyclines.
7.Chemoprophylaxis to contacts – tetracyclines,
doxycyclines
Cholera: Tertiary Prevention
Disability Limitation:
Investigation of the epidemic to spot the source and
do the needful.
Sanitation: Water supply-Excreta disposal-Fly
control-Disinfection [WEFD]
Rehabilitation:
Vocational support to the family if the head of
family is the lost. [Intersectoral co-operation]
Psychological: Moral support to the family of a dead
patient.
Assignment
Write short notes : 5 marks each
1.Epidemilogy of Cholera
2.Immunoprophylaxis against Cholera
3.Early diagnosis and treatment of Cholera
Long Answer questions: 10 marks
Describe the epidemiology of cholera.
THANKS

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Cholera:Brief Epidemiology and Prevention

  • 1. Cholera: Brief Epidemiology & Prevention DR. Rambadan P. Chauhan MD (PSM), ACME (MET) Professor-Community Medicine BKLWR Medical College- Sawarde, District-Ratnagiri chauhanrambadan@gmail.com 5/11/2021 1 Dr Rambadan Chauhan
  • 2. Lecture Objectives: (Cholera) At the end of lecture you {student (s)} should be able to understand, Epidemiology of Cholera Prevention of cholera
  • 3. Cholera Agent: Vibrio Cholerae 2 types :Classical & Eltor. El-Tor: 3 sub types Ogawa,Hikojima & Inaba . MCC=El Tor Hybrid Host: All ages & sexes. Environment: Pilgrimage, marriage, fairs & festivals, Poor sanitation. MOT: Feco-oral routine. Contaminated drinks & foods
  • 4. Cholera Incubation Period: Common: 1-2 days Range: few hours to 5 days Infective Material: Stool and vomit of cases and carriers. Carrier types: Incubatory 1-5 days. Convalescent carriers 2-3 weeks. Contact/Healthy carriers for 10 days. Chronic Carriers from 3 months to 10 years. Reservoir-Gall bladder. Clinical Features: Profuse painless watery diarrhea with vomiting. Rapid severe dehydration. 3stages-Evacuation, collapse & recovery/death. Investigations: 1.Microscopy-Gram negative with curved rod with characteristic scintillating type of movements. 2.Culture 3.Biochemical tests 4.Serology etc
  • 5. Cholera: Primary Prevention Primary Prevention: 1.Safe water and sanitary latrines. 2.Hand washing with soap and water. 3.Health education Specific Protection: Cholera vaccine: 3 months before Pilgrimage, marriage, fairs & festivals. 3 types of oral vaccines: 1. Dukoral (WC-rBS) 2.Sanchol and mORCVAX 3. Euvichol Dosage Schedule: initially 2/3 doses with 1 week to 1 month interval. Boosters every 3 years. Age: 2 years and above
  • 6. Cholera:Secondary Prevention EDAT: V NEERAC 1.Verification of diagnosis : Hanging drop & Biochemical tests 2.Notification: Local-National & International 3.Early case finding: The users of the contaminated source 4.Establishment of treatment centres : Temporary/Regular 5.Rehydration therapy: ORS & IVT [75-100 ml/kg/day], Rapid. 6.Antibiotics- Ciprofloxacin, Azithromycin, Tetracyclines. 7.Chemoprophylaxis to contacts – tetracyclines, doxycyclines
  • 7. Cholera: Tertiary Prevention Disability Limitation: Investigation of the epidemic to spot the source and do the needful. Sanitation: Water supply-Excreta disposal-Fly control-Disinfection [WEFD] Rehabilitation: Vocational support to the family if the head of family is the lost. [Intersectoral co-operation] Psychological: Moral support to the family of a dead patient.
  • 8. Assignment Write short notes : 5 marks each 1.Epidemilogy of Cholera 2.Immunoprophylaxis against Cholera 3.Early diagnosis and treatment of Cholera Long Answer questions: 10 marks Describe the epidemiology of cholera.