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Enter any bar or public place and canvass opinions on
cannabis and there will be a different opinion for each
person canvassed. Some opinions will be well-informed from
respectable sources while others will be just formed upon no
basis at all. To be sure, research and conclusions based on
the research is difficult given the long history of
illegality.
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Nevertheless, there is a groundswell of opinion that cannabis
is good and should be legalised. Many States in America and
Australia have taken the path to legalise cannabis. Other
countries are either following suit or considering options.
So what is the position now? Is it good or not?

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The National Academy of Sciences published a 487 page report
this year (NAP Report) on the current state of evidence for
the subject matter. Many government grants supported the work
of the committee, an eminent collection of 16 professors.
They were supported by 15 academic reviewers and some 700
relevant publications considered. Thus the report is seen as
state of the art on medical as well as recreational use. This
article draws heavily on this resource.

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The term cannabis is used loosely
here to represent cannabis and
marijuana, the latter being sourced
from a different part of the plant.
More than 100 chemical compounds
are found in cannabis, each
potentially offering differing
benefits or risk.

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A person who is "stoned" on smoking cannabis might experience
a euphoric state where time is irrelevant, music and colours
take on a greater significance and the person might acquire
the "nibblies", wanting to eat sweet and fatty foods. This is
often associated with impaired motor skills and perception.
When high blood concentrations are achieved, paranoid
thoughts, hallucinations and panic attacks may characterize
his "trip".

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In the vernacular, cannabis is often characterized as "good
shit" and "bad shit", alluding to widespread contamination
practice. The contaminants may come from soil quality (eg
pesticides & heavy metals) or added subsequently. Sometimes
particles of lead or tiny beads of glass augment the weight
sold.

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A random selection of therapeutic effects appears here in
context of their evidence status. Some of the effects will be
shown as beneficial, while others carry risk. Some effects
are barely distinguished from the placebos of the research.

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Cannabis in the treatment of epilepsy is inconclusive on
account of insufficient evidence.
Nausea and vomiting caused by chemotherapy can be ameliorated
by oral cannabis.
A reduction in the severity of pain in patients with chronic
pain is a likely outcome for the use of cannabis.

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Spasticity in Multiple Sclerosis
(MS) patients was reported as
improvements in symptoms.
Increase in appetite and decrease
in weight loss in HIV/ADS patients
has been shown in limited evidence.

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According to limited evidence cannabis is ineffective in the
treatment of glaucoma.
On the basis of limited evidence, cannabis is effective in
the treatment of Tourette syndrome.
Post-traumatic disorder has been helped by cannabis in a
single reported trial.
Limited statistical evidence points to better outcomes for
traumatic brain injury.
There is insufficient evidence to claim that cannabis can
help Parkinson's disease

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Limited evidence dashed hopes that cannabis could help
improve the symptoms of dementia sufferers.
Limited statistical evidence can be found to support an
association between smoking cannabis and heart attack.
On the basis of limited evidence cannabis is ineffective to
treat depression
The evidence for reduced risk of metabolic issues (diabetes
etc) is limited and statistical.
Social anxiety disorders can be helped by cannabis, although
the evidence is limited. Asthma and cannabis use is not well
supported by the evidence either for or against.

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Post-traumatic disorder has been helped by cannabis in a
single reported trial.
A conclusion that cannabis can help schizophrenia sufferers
cannot be supported or refuted on the basis of the limited
nature of the evidence.
There is moderate evidence that better short-term sleep
outcomes for disturbed sleep individuals.

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Pregnancy and smoking cannabis are
correlated with reduced birth
weight of the infant.
The evidence for stroke caused by
cannabis use is limited and
statistical.
Addiction to cannabis and gateway
issues are complex, taking into
account many variables that are
beyond the scope of this article.
These issues are fully discussed in
the NAP report.
CANCER
The NAP report highlights the
following findings on the issue of
cancer:
The evidence suggests that smoking
cannabis does not increase the risk
for certain cancers (i.e., lung,
head and neck) in adults.
There is modest evidence that
cannabis use is associated with one
subtype of testicular cancer.
There is minimal evidence that
parental cannabis use during
pregnancy is associated with
greater cancer risk in offspring.

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RESPIRATORY DISEASE
The NAP report highlights the following findings on the issue
of respiratory diseases:
Smoking cannabis on a regular basis is associated with
chronic cough and phlegm production.
Quitting cannabis smoking is likely to reduce chronic cough
and phlegm production.

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IMMUNE SYSTEM
The NAP report highlights the following findings on the issue
of the human immune system:
There exists a paucity of data on the effects of cannabis or
cannabinoid-based therapeutics on the human immune system.
There is insufficient data to draw overarching conclusions
concerning the effects of cannabis smoke or cannabinoids on
immune competence.

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