Kala azar.pptx

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Dr Pushkar Kumar

This ppt in short deals with kala-azar...

Health & Medicine

VISCERAL LEISHMANIASIS (KALA-AZAR)
DR. PUSHKAR KUMAR
MBBS,MD(GENERAL MEDICINE)
JUNIOR RESIDENT
DEPARTMENT OF MEDICINE
DMCH,LAHERIASARAI,DARBHANGA

INTRODUCTION
• Zoonotic disease
• About 20 species of
leishmania are
described till date
• Vector-Sand fly
• Local name- Balu
Makkhi
• Host-canine and
rodents
• Accidental host-
Human

Cutaneous
leishmaniasis-
Painless satellite
lesion
Mucocutaneous
leishmaniasis-
ESPUNDIA

• Side effects of
pentavalent
antimonial -
1. cardiac toxicity,
2. arrhythmia,
3. pronged QT,
4. Arthralgia
5. Myalgia
• Pancreatitis,
hypoglycemia and
rash
• Dose-20 mg/kg/day
in divided dose im/iv
for 20 days

DOSING 0F DRUGS USED IN
KALA-AZAR
• Pentamidin isothionate-2-4 mg/kg im for 15 days
(Adverse effect-Type I DM)
• Paromycin-11mg/kg im 21 days
• Side effects-ototoxicity
• Treatment of cutaneous leishmaniasis
1.Pentavalent antimony- 20 days,
2.Antifungal-Azole and allopurinol
• Topical therapy-Intralesional antimony compound and
paramomycin

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