1. CECILIA FRECHA PhD
Scientific Researcher, CONICET
Born 25/10/1976 in Buenos Aires, Argentina
Laboratory of Neurotoxins and Neuroplasticity (LaNyN),
Institute of Cellular Biology and Neuroscience (IBCN), Faculty of Medicine, UBA
Paraguay 2155, 2nd & 3rd Floor. Zip Code 1121, CABA, Argentina. Tel: +541159509500
ext 2219 frechacecilia@gmail.com
EDUCATION
RESEARCH EXPERIENCE
European PhD
University of Granada.
Supervisor: Dr. Francisco Martin Molina
Title: Physiologically regulated lentiviral vector for gene therapy of
Wiskott-Aldrich syndrome.
29/06/2007
Diploma of Advanced Studies (DEA)
Degree in Cellular and Molecular Immunology
Institute of Parasitology and Biomedicine IPB “Lopez-Neyra” –
Spanish Research Council (CSIC), Granada, Spain.
Supervisor: Dr. Francisco Martín Molina
Title: Optimization of lentiviral vectors for gene therapy of
immunodeficiencies.
20/12/2005
Bachelor’s degree in Biochemistry
Universidad de Buenos Aires, Argentina
Facultad de Farmacia y Bioquímica
10/05/2002
2. Cecilia Frecha
Page 2
FELLOWSHIPS
Scientific Researcher (Fix Position)
Category II, Argentinean Research Council (CONICET).
Institute of Cellular Biology and Neuroscience (IBCN),
Laboratory of Neurotoxins and Neuroplasticity (LaNyN),
Faculty of Medicine, University of Buenos Aires
Oct 2014
Researcher
Argentinean Research Council (CONICET).
Institute of Cellular Biology and Neuroscience (IBCN),
Laboratory of Neurotoxins and Neuroplasticity (LaNyN),
Faculty of Medicine, University of Buenos Aires
Supervisor: Dr. Diana Jerusalinsky.
Dec 2013-Oct 2014
Postdoctoral Position
International Agency for Research on Cancer (IARC)- WHO
Team: Infections and Cancer Biology. Supervisor: Dr.
Massimo Tommasino
May 2012- May 2013
Postdoctoral Position
Ecole Normale Supérieure de Lyon. Laboratory of Viral
Enveloppes and Retrovirus Engineering. Supervisor: Dr.
François-Loic Cosset
Apr 2009-May 2012
Postdoctoral Position
Ecole Normale Supérieure de Lyon. Laboratory of Viral
Enveloppes and Retrovirus Engineering. Supervisor: Dr.
François-Loic Cosset
May 2007- May 2009
PhD Fellow Nov 2004 - May 2007
Institute of Parasitology and Biomedicine IPB “Lopez-Neyra” –
Spanish Research Council (CSIC), Granada, Spain.
Supervisor: Dr. Francisco Martin Molina.
Graduate Research Assistant
University of Granada. Laboratory of Molecular Immunology.
Supervisor: Dr. E. García-Olivares, Profesor de la Universidad de
Granada.
2004-2003
Undergraduate Research Assistant
Universidad de Buenos Aires, FFyB, Laboratorio de Inmunología
Celular. Supervisor: Dr. M. Estela Roux.
1999-2002
3. Cecilia Frecha
Page 3
PRIZES AND DISTINCTIONS
PUBLICATIONS
ResearcherID: A-5786-2010
Scientific Researcher (Fix Position)
Category II
Argentinean Research Council (CONICET), Argentina
Oct 2014
Research Contract
Argentinean Research Council (CONICET), Argentina
Dec 2013-Oct 2014
Post-Doctoral Fellowship
International Agency for Research on Cancer (IARC)- WHO
Marie Curie Actions FP7, France
May 2012- May 2013
Post-Doctoral Fellowship
European Consortium for Persisting Transgenesis (PERSIST) FP7,
France
May 2010 - May 2012
Post-Doctoral Fellowship
French Agency for Research on AIDS, ANRS, France
May 2007 - May 2010
PhD Fellowship
Andalusian Research Council, Spanish Research Agency,
Spain
Nov 2004 - May 2007
Graduate Research Fellowship Nov 2003- Nov 2004
San Cecilio’s Hospital Foundation, Spain
Undergraduate Research Fellowship
Faculty of Pharmacy and Biochemistry, University of Buenos Aires,
Argentina
2000-2002
Young Investigator Award Awarded by the European Consortium
for Adoptive Engineering T cell targeting to activate cancer killing.
(ATTACK), Montpellier, France
2010
Best Oral Presentation Award Awarded by the French Society for
Gene and Cell Therapy. Paris, France.
2009
4. Cecilia Frecha
Page 4
Original Papers
Frecha C, Chevalier SA, van Uden P, Rubio I, Siouda M, Saidj D, Cohen C, Lomonte P, Accardi R,
Tommasino M.Expression of the Epidermodysplasia Verruciformis-Associated Genes EVER1 and
EVER2 Is Activated by Exogenous DNA and Inhibited by LMP1 Oncoprotein from Epstein-Barr
Virus. J Virol. Jan 15;89(2):1461-7. 2015
Girard-Gagnepain A, Amirache F, Costa C, Lévy C, Frecha C, Fusil F, Nègre D, Lavillette D,
Cosset FL, Verhoeyen E.Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene
transfer into early-cytokine-stimulated and resting HSCs. Blood. Aug 21;124(8):1221-31. 2014
Siouda M, Frecha C, Accardi R, Yue J, Cuenin C, Gruffat H, Manet E, Herceg Z, Sylla BS,
Tommasino M. Epstein-Barr virus down-regulates tumor suppressor DOK1 expression.
PLoS Pathog. May 8;10(5):e1004125. 2014
Lévy C, Amirache F, Costa C, Frecha C, Muller CP, Kweder H, Buckland R, Cosset FL, Verhoeyen
E. Lentiviral Vectors Displaying Modified Measles Virus gp Overcome Pre-existing Immunity in In
Vivo-like Transduction of Human T and B Cells. Mol Ther. Sep;20(9):1699-712. 2012
Schoenhals M, Frecha C, Bruyer A, Caraux A, Veyrune JL, Jourdan M, Moreaux J, Cosset FL,
Verhoeyen E, Klein B. Efficient transduction of healthy and malignant plasma cells by lentiviral
vectors pseudotyped with measles virus glycoproteins. Leukemia. Jul;26(7):1663-70. 2012
Humbert JM, Frecha C, Amirache Bouafia F, N'guyen TH, Boni S, Cosset FL, Verhoeyen E, Halary
F. Measles virus glycoproteins pseudotyped lentiviral vectors are highly superior over VSV-G
pseudotypes for genetic modification of monocyte-derived DCs. J Virol. May;86(9):5192-203. 2012
Frecha C*, Costa C*, Nègre D, Amirache F, Trono D, Rio P, Bueren J, Cosset FL, and Verhoeyen E.
A novel lentivector targets gene transfer into hHSC in marrow from patients with BM-failure-
syndrome and in vivo in humanized mice. Blood. Feb 2;119(5):1139-50. 2012
Frecha C, Lévy C, Costa C, Nègre D, Amirache F, Buckland R, Russell SJ, Cosset FL, Verhoeyen
E. Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent
lymphocytes requires binding to both SLAM and CD46 entry receptors. J Virol. Jun;85(12):5975-85.
2011
Frecha C*, Levy C*, Costa C, Rachinel N, Salles G, Cosset FL, and Verhoeyen E. Lentiviral
vectors and transduction of human cancer B-cells. Blood Jul 22;116(3):498-500. 2010
Frecha C, Lévy C, Cosset FL, Verhoeyen E. Advances in the field of lentivector-based transduction
of T and B lymphocytes for gene therapy. Mol Ther. Oct;18(10):1748-57. 2010
5. Cecilia Frecha
Page 5
Frecha C, Costa C, Lévy C, Nègre D, Russell SJ, Maisner A, Salles G, Peng KW, Cosset FL,
Verhoeyen E. Efficient and stable transduction of resting B lymphocytes and primary chronic
lymphocyte leukaemia cells using measles virus gp displaying lentiviral vectors. Blood. Oct
8;114(15):3173-80. 2009
Toscano MG, Benabdellah K, Muñoz P, Frecha C, Cobo M, Martín F. Was cDNA sequences
modulate transgene expression of was promoter-driven lentiviral vectors. Hum Gene Ther. Nov;
20(11):1279-90. 2009
Frecha C., Costa C., Nègre D., Gauthier M., Peng K., Russell S., Cosset FL. and Verhoeyen E.
Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral
vector pseudotyped with measles virus glycoproteins., Blood. Dec 15;112(13):4843-52. 2008
Frecha C, Toscano MG, Costa C, Saez-Lara MJ, Cosset FL, Verhoeyen E, Martin F. Improved
lentiviral vectors for Wiskott-Aldrich syndrome gene therapy mimic endogenous expression profiles
throughout haematopoiesis. Gene Ther. Jun;15(12):930-41. 2008
Frecha C., Szécsi J., Cosset F.L. and Verhoeyen E. Strategies for targeting lentiviral vectors. Curr
Gene Ther. Dec;8(6):449-60. 2008
Toscano MG, Frecha C, Benabdellah K, Cobo M, Blundell M, Thrasher AJ,Garcia-Olivares E,
Molina IJ, Martin F. Hematopoietic-specific lentiviral vectors circumvent cellular toxicity due to
ectopic expression of Wiskott-Aldrich syndrome protein. Hum Gene Ther. Feb;19(2):179-97. 2008
Sáez-Lara-MJ, Frecha C, Martín F, Rosa M., Santisteban-Bailón, Abadía F, Gil A, Fontana L.
Transplantation of human CD34+ stem cells from umbilical cord blood to rats with thioacetamide–
induced liver cirrhosis. Xenotransplantation. Nov;13(6):529-35. 2006
Andreu N, García-Rodríguez M, Volpini V, Frecha C, Molina I, Fontan G and Fillat C. A novel
WASP complex mutation identified in a WAS patient results in an aberrant product at the C-terminus
from two transcripts with unusual polyA signals. J. Hum. Genet. 51(2):92-7. 2006
Munoz-Fernandez R, Blanco FJ, Frecha C, Martin F, Kimatrai M, Abadia-Molina AC, García-
Pacheco JM, Olivares EG. Follicular dendritic cells are related to bone marrow stromal cell
progenitors and to myofibroblasts. J Immunol. Jul 1;177(1):280-9. 2006
Martin F, Toscano M, Blundell M, Frecha C, Srivastava G, Santamaria M, Thrasher A, Molina I.
Lentiviral vectors transcrptionally targeted to hematopoietic cells by wasp gene proximal promoter
sequences restore Wiskott-Aldrich Syndrome defects. Gene Ther. Apr;12(8):715-23. 2005
Toscano MG, Frecha C, Ortega C, Santamaria M, Martin F, Molina IJ. Efficient lentiviral
transduction of Herpesvirus saimiri immortalized T cells as a model for gene therapy in primary
immunodeficiencies Gene Ther. Jun;11(12):956-61. 2004
6. Cecilia Frecha
Page 6
Olmos S, Blois S, Frecha C, Marquez G and Roux ME. Cytokines mediating inflammation in a
model of secondary immunodeficiency in wistar rats: immunomodulation triggered by
thymomodulins. J.Inflammation Nov;4 (2) : 29-39. 2006
Delettieres D, Frecha C, Roux ME. Early appearance of TNF-alpha and other cytokines in bronchus
associated lymphoid tissues (BALT) from growing Wistar rats. What is the role of TNF-alpha? Clin
Dev Immunol. Sep-Dec;11(3-4):253-9. 2004
Roux, M.E., Marquez, M.G., Olmos S., Frecha C. and Florin-Christensen, A. Compartmentalisation
between gut and lung mucosa in a model of secondary immunodeficiency. Effect of Thymomodulin.
Int J Immunopathol Pharmacol. May-Aug;16(2):151-6. 2003
Book Chapters
Frecha C, Fusil F, F Cosset FL, and Verhoeyen E. In vivo gene delivery into hCD34+ cells in a
humanized mouse model. Methods Mol Biol. 737:367-90. 2011
Patents
Verhoeyen, E, Frecha, C, Costa, C. and Cosset, FL. Lentiviral vectors for targeted gene transfer into
hCD34+ cells and T-cells. (European Patent application N° 07290918.7, applicant: INSERM,
23/07/2008)
7. Cecilia Frecha
Page 7
COMMUNICATIONS TO INTERNATIONAL MEETINGS (37)
C Levy, F Amirache, C Costa, C Frecha, H Kweder, R Buckland, E Verhoeyen, F L Cosset.
Engineering Measles Virus glycoproteins pseudotypes for in vivo gene transfer into T and B cells.
European Society of Gene and Cell Therapy British Society for Gene Therapy Collaborative
Congress 2011 October 27–31, 2011 The Brighton Centre, Brighton United Kingdom.
A Girard, F Amirache, C Costa, C Frecha, D Negre, D Lavillette, F-L Cosset, E Verhoeyen. A
new lentiviral vector pseudotype outperforms by far VSV-G-LVs for gene transfer into
hematopoietic stem cells. European Society of Gene and Cell Therapy British Society for Gene
Therapy Collaborative Congress 2011 October 27–31, 2011 The Brighton Centre, Brighton
United Kingdom.
Cecilia Frecha, Camille Lévy, Caroline Costa, Didier Nègre, Nicolas Rachinel, Gilles Salles, FL
Cosset and Els Verhoeyen. A novel lentiviral vector pseudotype allows efficient transduction of
quiescent human T and healthy and malignant B lymphocytes. Cellular Therapy of Cancer
Symposium. September 24-27th , 2010, Montpellier, France. Oral Presentation and Young
Investigator´s Award
Camille Lévy, Cecilia Frecha, Caroline Costa, Nicolas Rachinel, Gilles Sales, François-Loic
Cosset, and Els Verhoeyen. Efficient gene transfer in quiescent malignant B cells by a Measles
virus gp pseudotyped lentiviral vector. 9ème congrès de la Société Francophone de Thérapie
Cellulaire et Génique, 13-15 Juin 2010, Paris, France. Poster presentation
Cecilia Frecha, Caroline Costa, Camille Lévy, Didier Nègre, Andrea Maisner, Stephen J. Russell,
Nicholas Rachinel, Gilles Salles, FL Cosset and Els Verhoeyen. Efficient gene transfer in
Quiescent healthy and cancer B cells by a Measles virus gp pseudotyped LV. 13th Annual
meeting of the American Society for Gene and Cell Therapy; May 17- 22nd 2010, Washington,
USA. Oral presentation.
Cecilia Frecha. Measles virus gp-pseudotyped lentiviral vectors for transduction of quiescent B-
cells. 2nd PERSIST Annual Meeting, January 13-16th, 2010, Leukerbad, Switzerland. Oral
presentation
Cecilia Frecha, Caroline Costa, Camille Lévi, Didier Nègre, Steve Russell, Kay-Wey Peng, FL
Cosset and Els Verhoeyen. Measles virus gp pseudotyped LVs allow efficient transduction of
quiescent healthy and cancer B-cells. XVIIth Annual Congress of the European Society of Gene
and Cell Therapy, November 20-25th, 2009, Hannover, Germany. Oral presentation.
Cecilia Frecha, Camille Lévi, Caroline Costa, Didier Nègre, Steve Russell, FL Cosset and Els
Verhoeyen. Targeted lentiviral transduction of different cell types of the hematopoietic system. V
Congress of the Spanish Society of Gene and Cell Therapy, September 30th – October 2nd ,
2009, Granada, Spain. Oral presentation.
8. Cecilia Frecha
Page 8
Cecilia Frecha, Caroline Costa, Camille Lévi, Didier Nègre, Steve Russell, Kay-Wey Peng, FL
Cosset and Els Verhoeyen. Measles virus gp pseudotyped LVs allow efficient transduction of
quiescent healthy and cancer B-cells. V Congress of the Spanish Society of Gene and Cell
Therapy, September 30th – October 2nd , 2009, Granada, Spain. Oral Presentation
Pilar Muñoz, Miguel G. Toscano, Karim Benabdellah, Cecilia Frecha, Marien Cobo and
Francisco Martin. Wasp cDNA sequences modulate transgene expression of WAS promoter-
driven lentiviral vectors. V Congress of the Spanish Society of Gene and Cell Therapy,
September 30– October 02 , 2009, Granada, Spain. Poster presentation
Frecha C, Costa C, Nègre D, Russell S, Peng KW, Cosset FL and Verhoeyen E. Measles virus gp
pseudotyped LVs allow efficient transduction of quiescent B-cells by using a highway to the
nucleus. 8ème congrès de la Société Francophone de Thérapie Cellulaire et Génique, 21-23 Juin
2009, Paris, France. Best Oral Presentation Award
Frecha, C. Exploiting the natural tropism of measles virus glycoproteins to target LV transfer to
quiescent blood lymphocytes. European consortium CONSERT VI annual meeting, January
14-17, 2009, Leukerbad, Switzerland. Oral presentation.
Frecha, C. Costa, C, Nègre, D, Gauthier, Cosset, FL, and Verhoeyen, E. Stable transduction of
quiescent T- cells without induction of cycle progression by a novel lentiviral vector pseudotyped
with measles virus glycoproteins. European Society of Gene Therapy, 16th
Verhoeyen, E, Frecha C, Costa, C, Granier, C, Negre, D, Cosset, FL. New lenti-vector co-
displaying RD114 and SCF target gene transfer to HSCs in vivo. European Society of Gene
Therapy, 16th Annual Congress, November 13-16, 2008 Bruges, Belgium. Poster presentation
Toscano, M, Munoz, P, Benabdellah K, Frecha, C. Cobo, M, Martin F. WASP intragenic
sequences enhance hematopoietic specificity of WASp-promoter-driven lentiviral vectors.
European Society of Gene Therapy, 16th Annual Congress, November 13-16, 2008 Brugge,
Belgium. Poster presentation
Frecha, C., Costa, C, Nègre, D, Gauthier, E, Russell, SJ, Cosset, FL, and Verhoeyen, E “Stable
transduction of quiescent T-cells without induction of cycle progression by a novel lentiviral
vector pseudotyped with measles virus glycoproteins.” 7th Congress of the French Society for
Gene and Cell Therapy, June 15-17, 2008 Presqu’ile de Giens, France. Oral presentation.
Verhoeyen, E, Frecha, C., Costa, C, Granier, C, Nègre, D, Cosset, FL “New lenti vectors co-
displaying RD114 and SCF target gene transfer to HSCs in in vivo-like conditions.” 7th Congress
of the French Society for Gene and Cell Therapy, June 15-17, 2008 Presqu’ile de Giens, France.
Poster presentation
9. Cecilia Frecha
Page 9
Frecha, C. “Improved lentiviral vectors for wiskott-aldrich syndrome gene therapy mimic
endogenous expression profiles throughout haematopoiesis” 4th CONSERT Annual meeting,
January 24-26, 2008, Leukerbad Switzerland. Oral presentation
Frecha, C, Verhoeyen E, Toscano M, Costa C, Cosset FL, and Martin F. “Lentiviral vectors for
wiskott-aldrich syndrome gene therapy mimic endogenous expression profiles throughout
haematopoiesis” European Society of Gene Therapy, 15th Annual Congress, October 27-30,
2007 Rotterdam, The Netherlands. Oral presentation
Frecha, C, Toscano, M, Verhoeyen,E, Cosset,FL, Martin, F “Study of the performance of a
lentiviral vector carrying a fragment of the WASP proximal promoter in the CD34-derived
haematopoietic lineages” European Society of Gene Therapy, 14th Annual Congress, November
9-12, 2006 Athens, Greece. Poster presentation
Toscano, M, Benabdellah, K, Frecha, C, Molina, I, Martin, F “ Gene therapy of haematopoietic
disorders: Fine tunning of therapeutic vectors” European Society of Gene Therapy, 14th Annual
Congress, November 9-12, 2006 Athens, Greece Poster presentation
C.Frecha, M. Toscano, A. Thrasher, F.Martín. “Promoter regulation study of a haematopoietic-
specific lentiviral vector in umbilical cord blood-derived CD34 cells”. European Society of Gene
Therapy, 13th Annual Congress, October 29- November 1st 2005, Prague, Czech Republic
Poster presentation
C.Frecha, K. Benabdellah, MG Toscano, F.Martín. “ Restriction analyses in lentivirus vector-
transduced CD34+ cells from umbilical cord blood”. European Society of Gene Therapy, 13th
Annual Congress, October 29- November 1st 2005, Prague, Czech Republic Poster presentation
K. Benabdellah, MG Toscano, C. Frecha, A Thrasher, F. Martin “ Lentiviral vectors for
haematopoietic-specific expression”. European Society of Gene Therapy, 13th Annual Congress,
October 29- November 1 2005, Prague, Czech Republic Poster presentation
MG Toscano, C Frecha, K Benabdellah, A J Thrasher, F Martin, I J Molina “ Moderate ectopic
WASP expression by lentiviral vectors does not alter cell viability, but overexpression results in
toxic effects in non-haematopoietic cells.” European Society of Gene Therapy, 13th Annual
Congress, October 29- November 1 2005, Prague, Czech Republic Poster presentation
F.Martín , M. Toscano, M.Blundell, C.Frecha, G.K.Srivastava, M. Santamaría, A. Thrasher, I.J.
Molina “ Reconstitución functional de células de pacientes con el Síndrome de Wiskott-Aldrich
mediante vactores lentivirales específicos de células hematopoyéticas.” XXX Congress of the
Spanish Society of Immunology, May 25- 28 2004, Santander, Spain. Poster presentation
10. Cecilia Frecha
Page 10
M. Toscano, C.Frecha, I.J. Molina, F.Martín “ Diagnóstico de pacientes con Síndrome de
Wiskott-Aldrich mediante anticuerpos monoclonales con patrones diferenciados de reactividad en
Citometría y Western Blot.” XXX Congress of the Spanish Society of Immunology. May 25- 28
2004, Santander, Spain. Poster presentation
M. Toscano, F.Martín , C.Frecha, A. Thrasher, I.J. Molina “ Lentiviral vectors are efficient tools
to achieve stable gene expression in Herpesvirus Saimiri-immortalized T cell lines”. European
Society of Gene Therapy, 11th Annual Congress, November 14-17 2003, Edinburgh, UK Poster
presentation
I.J.Molina, M.García Toscano, C.Frecha, C.Ortega, A.Trasher, M.Santamaría, F.Martín “Vectores
lentivirales conteniendo el gen terapéutico: hacia una expresión regulada y estable en protocolos
de terapia génica.” XXIX Congress of the Spanish Society of Immunology, May 27 - 30 2003,
Cádiz, Spain. Poster presentation
M.García Toscano, F.Martín C.Frecha, C.Ortega, M.Santamaría, I.J.Molina “Modelos de rescate
en inmunodeficiencias primarias mediante transducción de célulasT inmortalizadas con
Herpesvirus Saimiri con vectores lentivirales.” XXIX Congress of the Spanish Society of
Immunology May 27 - 30 2003, Cádiz, Spain Poster presentation
I.J. Molina, M. Toscano, C.Frecha, M.Santamaría, M. Blumdell, A. Thrasher F.Martín “ Toward
gene therapy of Wiskott-Aldrich Syndrome with regulated lentiviral vectors” European Society of
Gene Therapy, 11th Annual Congress, November 14-17 2003, Edinburgh, UK Poster presentation
Olmos S, Frecha CA, Blois SM, et al. Relationship between TCR γδ T cells with TNFα and NFk
B in intestinal intraepithelial lymphocytes (iIEL) in a model of secondary immunodeficiency in
Wistar rats 42nd Annual Meeting of the American Society for Cell Biology, Dec 14-18, 2002 S
Francisco, CA. Mol Biol of the Cell 13: 162A-163A Meeting Abstract: 911 Published: NOV
2002
S.M. Venturiello, M.L. Verzoletti, C.Frecha, M.E.Roux. “Study of different cell phenotypes in
Bronchus Associated Lymphoid Tissue (BALT) in early Trichinella spirallis rat infection.” 10th
International Congress of Parasitology. August 4-9, 2002 Vancouver Convention and Exhibition
Centre, Vancouver, Canada. Poster presentation
Frecha C, Olmos S, Roux ME. “Relationship between γδT cells and cytokines in the Bronchus
Associated Lymphoid Tissue (BALT) of growing Wistar rats.” Society for Mucosal Immunology,
11th International Congress of Mucosal Immunology, June 16-20 2002, Wyndham Palace Resort
and Spa, Orlando, Florida, USA. Poster presentation
Frecha C, Olmos S, Arias K, Roux M.E. “Brochioalveolar Lymphocytes of Wistar rats.
Colocalisation between TCR γδ+ y TNFα+.” XLVII Annual Meeting of the Argentinean Society
of Clinical Research (SAIC) and XLXII Annual Meeting of the Argentinean Society of
Immunology (SAI) November 20-23 2002, Mar del Plata, Argentina Poster presentation
11. Cecilia Frecha
Page 11
LANGUAGES
Memberships
Frecha C, Olmos S, Sosa G, Roux ME. “Posnatal appearance of TNFa, IL-6 and IL-10 in the
(BALT) of growing Wistar rats.” Mucosal Immunology Satellite Meeting, 28-30 July, 2001,
Reykjavik, Iceland. Poster presentation
Olmos S, Frecha CA, Roux ME. Relationship between TH2 cytokines and DNA fragmentation.
Study in intestinal villi of Wistar rats. Mol Biol of he Cell 12: 419A Supplement: Suppl. S
Meeting Abstract: 2306 Published: NOV 2001
Frecha C, Olmos S, Roux ME. “Postnatal appearance of TNFa and IL-10 in the Bronchus
Associated Lymphoid Tissue (BALT) of growing Wistar rats.” VIII Ibero American Congress of
Cell Biology and I Congress of Cell Biology Peruvian Society, September 2001 Lima, Peru.
Poster presentation
Frecha C, Olmos S, Roux ME. “Early appearance of TNF-α, IL-6 e IL-10 in the BALT of
growing Wistar rats.”. XLVI SAIC y XLXI SAI, November 22 - 25 2000, Mar del Plata,
Argentina Poster presentation
• Spanish (mother tongue)
• English
• French
• International Society for Neurochemistry 2014
• European Society for Gene and Cell Therapy Since 2005
• Argentinean Society of Clinical Immunology 2000-2001