pharmaceutics basics

1. INTRODUCTION TO
DIFFERENT DOSAGE FORMS
Presented by:
Mr. Parimal Hadge
Datta Meghe Institute of Medical Science(DU)
Salod(H);Sawangi(M); Wardha:

2. Liquid dosage forms

3. Learning objectives:
The learner will be able to learn:
• Different types of dosage form
• Needs of dosage form
• Detail account on Liquid dosage form

4. Liquid dosage forms

5. It may be defined as “A solution is a liquid-preparation that
contains one or more soluble chemical substances dissolved in
a specified solvent”
 Liquid dosage forms are intended for External, Internal or
parenteral use.
 The component of the solution which is present in a large
quantity is known as “SOLVENT” where as the component
present in small quantity is termed as “SOLUTE”
They mainly classified in to two category namely as –
I) Monophasic Liquid dosage forms.
II) Biphasic liquid dosage forms.

6. Advantage
Immediately available for absorption.
Administration convenient, particularly for infants, psychotic
patients.
Easy to color, flavor & sweeten.
Liquids are easier to swallow than solids and are therefore
particularly acceptable for pediatric patient.
A solution is an homogeneous system and therefore the drug
will be uniformly distributed throughout the preparation.
Some drugs like aspirin, KCl can irritate gastric mucosa if used
orally as a solid dosage forms. But this effect can be reduce by
solution system.

7. Disadvantage
Less stable in aqueous system. Incompatibility is faster in
solution than solid dosage form.
Patients have no accurate measuring device.
Accident breakage of container results in complete loss.
Solution often provide suitable media for the growth of micro
organisms.
The taste of a drug, which is often unpleasant, is always more
pronounced when in solution than in a solid form.
 Bulky than tablets or capsule, so difficult to carry transport.

8. Monophasic liquid dosage forms

9. Monophasic liquid dosage forms are represent by true or colloidal
solution.
The component of the solution which is present in a large
quantity is known as “SOLVENT” where as the component
present in small quantity is termed as “SOLUTE”.
A solution is homogenous because the solute is an ionic or
molecular forms of subdivision.
In case of colloidal solutions, the solutes are present as
aggregates although they cannot be seen by necked eye or
ordinary microscope.
It is sub classified as –
I) Internal Use, II) External use

10. Monophasic Liquid Dosage
forms
Internal Use External Use
 Syrup
 Elixirs
 Linctuses
 Drops
 Liniments
 Lotions
 Gargles
 Mouth Wash
 Throat paints
 sprays
 Inhalations
 Nasal drops
 Eye drops
 Eye lotions
 Ear drops

11. References:
• R. M. Mehta text book for pharmaceutics I
• Lachman, A reference book for pharmaceutics
• Martin, A reference book for pharmaceutics

12. Thank you