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Orofacial Pain
Dr. Ossama El-Shall
Part 1 of 2
Pain
5/18/2021 9:03 PM Oelshall
“An unpleasant sensory
and emotional experience
associated with actual or
potential tissue damage,
or described in terms of
such damage.”
Orofacial pain (OFP) is the presenting
symptom of a broad spectrum of diseases
5/18/2021 9:03 PM Oelshall
Disease of the
oro-facial
structures
Generalized
musculoskeletal or
rheumatic disease
Peripheral or
CNS disease
Psychological
abnormality
As a symptom, it may be due to
The pain may be referred
from other sources
(eg. cervical muscles or
intracranial pathology).
or
OFP may also occur in the absence
of detectable physical, imaging, or
laboratory abnormalities
Cranial nerves responsible for orofacial pain
5/18/2021 9:03 PM Oelshall
 Trigeminal nerve,(CN V) is the dominant
nerve that relays sensory impulses from the
orofacial area to the central nervous system.
 Facial (CN VII),
 Glossopharyngeal (CN IX),
 Vagus (CN X) nerves
Trigeminal nerve
5/18/2021 9:03 PM Oelshall
 Skin of face,
 Forehead and scalp
 The top of the head
 Conjunctiva and bulb of the eye
 Oral and nasal mucosa
 External aspect of the tympanic membrane
 Teeth
 Anterior two-thirds of tongue
 Masticatory muscles
 TMJ
 Meninges of anterior and middle cranial fossae
The most common facial pain disorder resulted
from involvement of trigeminal nerve is
Trigeminal neuralgia
5/18/2021
5/18/2021 9:03 PM Oelshall
▪ One disease affecting the
trigeminal nerve is trigeminal
neuralgia.
▪ A person experiencing
trigeminal neuralgia may suffer
an episode of facial pain that can
last as long as two minutes.
▪ The cause of this disease is
not currently known, but it may
have to do with blood vessels
putting pressure on the trigeminal
nerve as it leaves the brain
stem.
trigeminal neuralgia
Facial (CN VII)
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•Bell’s palsy is a weakness or
paralysis of the muscles on one
side of the face.
•The facial nerve is often
damaged by inflammation and
causes one side of the face to
droop.
•Other symptoms of Bell’s palsy
may be pain in or behind the
ear, drooping, excessive tearing
or dry eyes, numbness on one
side of the face, or increased
sensitivity to sound.
Bell’s Palsy
Glossopharyngeal (CN IX)
5/18/2021 9:03 PM Oelshall
 Mucosa of the pharynx;
 Palatine tonsils;
 Posterior one-third of the
tongue;
 Internal surface of the
tympanic membrane;
 Skin of the external ear
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Oelshall
Glossopharyngeal Neuralgia
Glossopharyngeal
neuralgia is a condition
believed to be caused by
irritation of the 9th
cranial nerve.
In which there are
repeated episodes of
severe pain in the
tongue, throat, ear, and
tonsils, which can last
from a few seconds to a
few minutes.
vagus (CN X)
5/18/2021 9:03 PM Oelshall
 Skin at the back of
the ear;
 Posterior wall and floor
of external auditory
meatus.
 Tympanic membrane.
 Meninges of posterior
cranial fossa.
 Pharynx.
 Larynx.
5/18/2021
 The vagus nerve is one of the largest nerve
systems in the body.
 The name vagus is Latin for "wandering,"
which describes the long and complicated
path this nerve takes through the body and
all of the different systems it comes in
contact with.
 In some cases this nerve is linked to medical
conditions such as low blood pressure, and in
other cases doctors will stimulate this nerve
to help treat disorders such as epilepsy.
Classification of the pain
5/18/2021 9:03 PM Oelshall
I- According to location
II- According to origin
I- According to location
5/18/2021 9:03 PM Oelshall
1- Neuritis
Inflammation of nerve ending induced by chemical,
microbial or toxic agents …..Burning sensation
II- Neuralgia
Paroxysmal pain along the course of the nerve
III-Psychogenic
No anatomical distribution, no clinical cause, not
interfere with eating or sleeping
II- According to origin
5/18/2021 9:03 PM Oelshall
1. Somatic pain
2. Neurogenous pain
3. Psychogenic pain
4. Referred pain
5. Vascular pain & headache.
SOMATIC PAIN
Somatic pain
It resulting from stimulation of normal neural
structures that innervates body tissue
5/18/2021 9:03 PM Oelshall
Origin: Skin & MM
Nature: Burning or pricking in nature
Character: Localized
Pts can identify its site
For Example:
Thermal pain: Pizza, hot instrument
Chemical pin: aspirin burn
Mechanical: traumatic ulcer
Superfacial ulceration due to systemic
disease eg; leukemia
Superficial
Deep
Deep pain
5/18/2021 9:03 PM Oelshall
joint
Muscle
Bone
Collection of
infected fluid in
bone as in
abscess
OVER
stretching or
Contraction
Rupture
of some fibers
TMJ
Character of deep somatic pain
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1- Bone pain will be throbbing in nature
2- May be referred involve area supplied with
the same sensory nerve
3- Muscle and joint pain: dull aching in nature.
4- Patient can hardly identify the source of the
pain.
II- According to origin
5/18/2021 9:03 PM Oelshall
1. Somatic pain
2. Neurogenous pain
3. Psychogenic pain
4. Referred pain
5. Vascular pain & headache.
NEUROGENOUS PAIN
Neurogenous pain
1-Trigeminal neuralgia
2-Glossopharyngeal n. Paroxysmal
3-Occipital neuralgia.
4- Post herpetic neuralgia
5- Post traumatic pain
6- Atypical odontalgia Non paroxysmal
7- Bell’s palsy
8- Frey’s auriculo-temporal syndrome
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II- According to origin
5/18/2021 9:03 PM Oelshall
1. Somatic pain
2. Neurogenous pain
3. Psychogenic pain
4. Referred pain
5. Vascular pain & headache.
PSYCHOGENIC PAIN
Psychogenic pain
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1- Burning mouth syndrome
2- Atypical orofacial pain
3- Myofacial pain dysfunction syndrome
II- According to origin
5/18/2021 9:03 PM Oelshall
1. Somatic pain
2. Neurogenous pain
3. Psychogenic pain
4. Referred pain
5. Vascular pain & headache.
Referred pain
Referred pain
 Is pain that perceived at a location other than the site
of the painful stimulus.
 An example is the case of angina pectoris brought on
by a myocardial infarction, where pain is often felt in
the neck, shoulders, and back rather than in the
thorax (chest), the site of the injury
 Referred pain is not felt at the site of disease but felt
at distance site
 Radiating pain is the extension of pain from original site
to another site with persistance of pain at original site
5/18/2021
II- According to origin
5/18/2021 9:03 PM Oelshall
1. Somatic pain
2. Neurogenous pain
3. Psychogenic pain
4. Referred pain
5. Vascular pain & headache.
Vascular pain & headache
Vascular pain & headache.
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1-Tension Headache
2-Migraine.
3-Cluster headache.
4-Cranial arteritis.
Tension headache
 A tension headache is the most common type
of headache.
 It can cause mild, moderate, or intense pain
behind your eyes and in your head and neck.
 Some people say that a tension headache feels
like a tight band around their forehead.
 Most people who experience tension
headaches have episodic headaches
5/18/2021
Migraine
 Migraine is a neurological condition that can
cause multiple symptoms.
 It's frequently characterized by intense,
debilitating headaches.
 Symptoms may include nausea, vomiting,
difficulty speaking, numbness or tingling,
and sensitivity to light and sound.
 Migraines often run in families and affect
all ages
5/18/2021
Cluster headache
 Cluster headache (CH) is a neurological
disorder characterized by recurrent
severe headaches on one side of the head,
typically around the eye.
 There is often accompanying eye watering,
nasal congestion, or swelling around the eye
on the affected side.
 These symptoms typically last 15 minutes to
3 hours
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Cranial arteritis.
 Or Temporal arteritis is a form of vasculitis
(inflammation of the blood vessels) in
temporal arteries.
 Also known as giant cell arteritis or Horton's
arteritis
 Frequently it causes headaches, scalp
tenderness, jaw pain and vision problems.
Untreated, it can lead to blindness.
5/18/2021
Cranial arteritis
5/18/2021
FACIAL NEURALGIAS
Facial Neuralgias
5/18/2021 9:03 PM Oelshall
The classic neuralgias that affect the craniofacial
region are a unique group of neurologic disorders
involving the cranial nerves and are characterized by
II.Neurogenous pain
Brief episodes of
shooting, often
electric shock–
like pain along
the course of
the affected
nerve branch.
pain-free periods
between attacks
and refractory
periods
immediately
after an attack,
during which a
new episode
cannot be
triggered
trigger zones on
the skin or
mucosa that
precipitate
painful attacks
when touched.
5/18/2021 9:03 PM Oelshall
These clinical characteristics differ from
neuropathic pain, which tends to be
- constant
- has a burning quality
- without the presence of trigger zones.
II.Neurogenous pain
Facial Neuralgias resulting in Neurogenous pain
1-Trigeminal neuralgia
2-Glossopharyngeal n. Paroxysmal
4- Post herpetic neuralgia
5- Post traumatic pain
6- Atypical odontalgia Non paroxysmal
7- Bell’s palsy
8- Frey’s auriculo-temporal syndrome
5/18/2021 9:03 PM Oelshall
TRIGEMINAL NEURALGIA
tic douloureux
5/18/2021 9:03 PM Oelshall
II.Neurogenous pain
People with this pain often twitch, which is where trigeminal
neuralgia gets its French nickname 'tic douloureux’,
meaning "painful twitch”.
TRIGEMINAL NEURALGIA
tic douloureux
5/18/2021 9:03 PM Oelshall
It is a sharp sever paroxysmal pain along the course of
trigeminal nerve with un-definitive etiology
It is the most common of the cranial neuralgias
• Chiefly affects individuals older than 50 years of age.
When younger individuals are involved, suspicion of a
detectable underlying lesion such as a tumor, an
aneurysm, or multiple sclerosis must be increased.
II.Neurogenous pain
Etiology and Pathogenesis.
5/18/2021 9:03 PM Oelshall
The cause of the majority of cases of TN remains
controversial, but approximately 10% of cases have
detectable underlying pathology such as:
1- Tumor of the cerebellar pontine angle,
2- Multiple sclerosis, MS
3- A vascular malformation.
The remainder of cases of TN (90%) are classified as
idiopathic.
Several theories exist regarding the etiology of TN.
II.Neurogenous pain
5/18/2021
5/18/2021 9:03 PM Oelshall
 The most widely accepted theory
is that a majority of cases of
TN are caused by an
atherosclerotic blood vessel
(usually the superior cerebellar
artery) pressing on and grooving
the root of the trigeminal nerve.
 This pressure results in focal
demyelinization and
hyperexcitability of nerve fibers,
which will then fire in response
to light touch, resulting in brief
episodes of intense pain.
II.Neurogenous pain
5/18/2021
5/18/2021 9:03 PM Oelshall
 Evidence for this theory includes the
observation that neurosurgery that removes
the pressure of the vessel from the nerve root
by use of a microvascular decompression
procedure eliminates the pain in a majority of
cases.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
 Additional evidence for this theory was obtained
from a study using tomographic magnetic
resonance imaging (MRI), which showed that
contact between a blood vessel and the
trigeminal nerve root was much greater on the
affected side.
5/18/2021
MRI can detect blood vessels (arrow) that may
be compressing the trigeminal nerve
Clinical Features
5/18/2021 9:03 PM Oelshall
The majority of patients with TN present with
characteristic clinical features, which include episodes
of intense shooting stabbing pain that lasts for a few
seconds and then completely disappears.
The pain has an electric shock–like quality and is
unilateral except in a small percentage of cases.
The maxillary branch is the branch that is most
commonly affected, followed by the mandibular branch
and (rarely) the ophthalmic branch. Involvement of
more than one branch occurs in some cases.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
 Pain in TN is precipitated by light touch on a
“trigger zone” present on the skin or mucosa within
the distribution of the involved nerve branch.
 Common sites for trigger zones include the nasolabial
fold and the corner of the lip.
II.Neurogenous pain
TRIGGER FACTORS
Touching Washing of
face Shaving
Teeth
cleaning Cold breeze Eating
Talking
Application
of lotions and
cosmetics
patients often protect the trigger zone with their hand or
an article of clothing.
5/18/2021 9:03 PM Oelshall
 Intraoral trigger zones can confuse the
diagnosis by suggesting a dental disorder,
and TN patients often first consult a dentist
for evaluation.
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5/18/2021 9:03 PM Oelshall
 Just after an attack,
there is a refractory
period when touching
the trigger zone will
not precipitate pain.
 The number of attacks
may vary from one or
two per day to several
per minute.
5/18/2021 9:03 PM Oelshall
 Half an inch finger sign: The patient points
to the trigger area with his finger away by
half an inch to avoid touching it.
II.Neurogenous pain
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Diagnosis.
 The diagnosis is based on the history of
shooting pain along a branch of the trigeminal
nerve, precipitated by touching a trigger
zone, and possibly examination that
demonstrates the shooting pain.
 A routine cranial nerve examination will be
normal in patients with idiopathic TN, but
sensory and/or motor changes may be evident
in patients with underlying tumors or other
CNS pathology.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
 Local anesthetic blocks, which temporarily
eliminate the trigger zone, may also be
helpful in diagnosis.
 Since approximately 10% of TN cases are
caused by detectable underlying pathology,
enhanced MRI of the brain is indicated to
rule out tumors, multiple sclerosis, and
vascular malformations.
Treatment
1. Medical
2. Surgical
5/18/2021
(tegratol),
1. Medical
5/18/2021
Mechanism of action of anticonvulsants,
antiepileptic or antiseizure drugs)
 Anticonvulsants suppress the excessive
rapid firing of neurons during seizures.
 Anticonvulsants also prevent the spread
of the seizure within the brain.
 Conventional antiepileptic drugs may block
sodium channels or enhance γ-
aminobutyric acid (GABA) function.
5/18/2021
 Several antiepileptic drugs have multiple or
uncertain mechanisms of action.
 Next to the voltage-gated sodium channels
and components of the GABA system, their
targets include GABAA receptors, the GAT-1
GABA transporter, and GABA transaminase.
 Additional targets include voltage-
gated calcium channels, SV2A, and α2δ.
 By blocking sodium or calcium channels,
antiepileptic drugs reduce the release of
excitatory glutamate, whose release is
considered to be elevated in epilepsy, but also
that of GABA. 5/18/2021
 This is probably a side effect or even the
actual mechanism of action for some
antiepileptic drugs, since GABA can itself,
directly or indirectly, act proconvulsively.
 Another potential target of antiepileptic
drugs is the peroxisome proliferator-
activated receptor alpha.
5/18/2021
5/18/2021 9:03 PM Oelshall
Since TN may have temporary or
permanent spontaneous remissions, drug
therapy should be slowly withdrawn if a
patient remains pain free for 3 months.
5/18/2021 9:03 PM Oelshall
 Clinicians treating TN must be aware that
drug therapy often becomes less effective
over time and that progressively higher
doses may be required for pain control.
 In cases in which drug therapy is
ineffective or in which the patient is unable
to tolerate the side effects of drugs after
trials of several agents, surgical therapy is
indicated.
II.Neurogenous pain
2. Surgical
SURGICAL
1. Injection of phenol or alcohol into
a trigeminal ganglion
2. Radiofrequency coagulation of a
branch
3. Sectioning of sensory root of
trigeminal ganglion inside the
cranium
4. Microvascular decompression
PREVENTION
While the condition itself can't be prevented, there are
a number of things patients can do to
avoid triggering attacks:
 Wash with cotton pads and warm water over the
face
 Rinse the mouth with water after eating, if tooth-
brushing triggers pain
 Eat and drink food and beverages at room temperature
 Chew on the unaffected side
 Eat soft foods, if eating is becoming a problem
POSTHERPETIC NEURALGIA
5/18/2021 9:03 PM Oelshall
II.Neurogenous pain
POSTHERPETIC NEURALGIA
5/18/2021 9:03 PM Oelshall
 Etiology and Pathogenesis.
Herpes zoster, is caused by the reactivation of latent
varicella-zoster virus that results in both pain and
vesicular lesions along the course of the affected
nerve.
Approximately 15 to 20% of cases of herpes zoster
involve the trigeminal nerve although the majority of
these cases affect the ophthalmic division of the fifth
nerve, resulting in pain and lesions in the region of the
eyes and forehead.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
Herpes zoster of the maxillary and mandibular
divisions is a cause of facial and oral pain as
well as of lesions.
In a majority of cases, the pain of herpes
zoster resolves within a month after the lesions
heal.
Pain that persists longer than a month is
classified as postherpetic neuralgia (PHN)
although some authors do not make the
diagnosis of PHN until the pain has persisted
for longer than 3 or even 6 months.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
 PHN may occur at
any age, but the
major risk factor
is increasing age.
 Elderly patients
also have an
increased risk of
experiencing severe
pain for an
extended period of
time.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
Clinical Manifestations.
Patients with PHN experience persistent pain,
paresthesia, hyperesthesia, and allodynia
months to years after the zoster lesions have
healed.
The pain is often accompanied by a sensory
deficit, and there is a correlation between
the degree of sensory deficit and the severity
of pain.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
Management.
 Many treatment options are available for
the management of PHN, and the method
chosen should depend on the severity of
the symptoms as well as the general
medical status of the patient.
 Treatment includes topical and systemic,
drug therapy and surgery.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
 Topical therapy includes the use of topical
anesthetic agents, such as lidocaine, or analgesics,
particularly capsaicin.
 Lidocaine used either topically or injected gives
short-term relief from severe pain.
 Capsaicin, an extract of hot chili peppers that
depletes the neurotransmitter substance when used
topically, has been shown to be helpful in reducing
the pain of PHN, but the side effect of a burning
sensation at the site of application limits its
usefulness for many patients.
II.Neurogenous pain
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 The use of tricyclic antidepressants is a well-
established method of reducing the chronic
burning pain that is characteristic of PHN.
 Because a significant number of elderly
patients cannot tolerate the sedative or
cardiovascular side effects associated with
tricyclic antidepressants, the use of other
drugs, particularly gabapentin, has been
advocated.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
 When medical therapy has been ineffective
in managing intractable pain, nerve blocks or
surgery at the level of the peripheral nerve
or dorsal root have been effective for some
patients.
 The best therapy for PHN is prevention.
There is evidence that the use of antiviral
drugs, particularly famciclovir, along with a
short course of systemic corticosteroids
during the acute phase of the disease may
decrease the incidence and severity of PHN
II.Neurogenous pain
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II.Neurogenous pain
Glossopharyngeal Neuralgia
5/18/2021 9:03 PM
Oelshall
Glossopharyngeal Neuralgia
Glossopharyngeal
neuralgia is a condition
believed to be caused by
irritation of the 9th
cranial nerve.
In which there are
repeated episodes of
severe pain in the
tongue, throat, ear, and
tonsils, which can last
from a few seconds to a
few minutes.
5/18/2021
Orofacial Pain
Dr. Ossama El-Shall
Part 2 of 2
POST-TRAUMATIC
NEUROPATHIC PAIN
5/18/2021 9:03 PM Oelshall
II.Neurogenous pain
POST-TRAUMATIC NEUROPATHIC PAIN
5/18/2021 9:03 PM Oelshall
Etiology and Pathogenesis.
 Trigeminal nerve injuries may result from
facial trauma or
surgical procedures, such as the removal of impacted
third molars, the placement of dental implants, the
removal of cysts or tumors of the jaws, or osteotomies.
 In some individuals, nerve injury results only in
numbness whereas others experience pain that may be
either spontaneous or triggered by a stimulus.
 The pain associated with nerve injury often has a burning
quality.
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
Total nerve section (neurotmesis)
Frequently causes permanent nerve damage, resulting in
anesthesia and/or dysesthesia.
Nerve injuries
Minor nerve injuries (neurapraxia)
Do not result in axonal degeneration but may cause
temporary symptoms of parasthesia for a few hours or days.
Serious nerve damage (axonotmesis)
Results in the degeneration of neural fibers although the
nerve trunk remains intact.
It cause symptoms for several months but have a good
prognosis for recovery after axonal regeneration is
complete.
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Manifestation
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Patients with nerve damage may experience
persistent burning pain arising from trauma plus:
II.Neurogenous pain
Anesthesia=loss of sensation
Paraesthesia=feeling of pins and needles
Allodynia=Pain by non painful stimuli
Hyperalgesia=Exaggerated response to
mild painful stimuli
Treatment
5/18/2021 9:03 PM Oelshall
 Systemic steroids during 1st week of
trauma
 Narcotic analgesic
 Topical capsaicin
 Tricyclic antidepressant
II.Neurogenous pain
Bell’s palsy
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II.Neurogenous pain
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It is peripheral facial weakness of
unknown etiology affecting any age group
of either sex.
How did Bell’s palsy get its name?
Sir Charles Bell was a Scottish surgeon
who described the nerve supply to the
facial muscles over 200 years ago.
Bell’s palsy
II.Neurogenous pain
5/18/2021 9:03 PM Oelshall
 Bell’s palsy is recognized as a unilateral
paralysis of the facial nerve.
 The dysfunction has been attributed to an
inflammatory reaction involving the facial
nerve.
 A relationship has been demonstrated between
Bell’s palsy and the isolation of herpes simplex
virus 1 from nerve tissues.
 Bell’s palsy must be differentiated from
other causes of facial nerve paralysis, such as
herpes zoster of the geniculate ganglion
(Ramsay Hunt syndrome).
Pathogenesis of Bell’s palsy
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Geneculate ganglion
Stylomastoid foramen
Facial nerve
Petrosal artery Stylomastoid artery
Fibrous C T
Middle meningeal External carotid
Inflammation of Facial
nerve inside the canal
demyelination & edema
loss blood supply
II.Neurogenous pain
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 Its etiology is unknown and there is no local
or systemic causes can be identified.
 It may be immunologically mediated or
associated with infection especially viral
infection
II.Neurogenous pain
5/18/2021
Clinically
5/18/2021 9:03 PM Oelshall
 Very rapid onset, patient may wake up with facial paralysis
 Bell’s palsy begins with slight pain around one ear and along the
mandibular angle, followed by an abrupt paralysis of the muscles on
that side of the face.
 The eye on the affected side stays open, the corner of the mouth
drops.
 As a result of masseter weakness, food is retained in both the upper
and lower buccal and labial folds.
 The facial expression changes remarkably.
 Due to impaired blinking, corneal ulcerations from foreign bodies can
occur.
 Involvement of the chorda tympani nerve leads to loss of taste
sensation on the anterior two-thirds of the tongue and reduced
salivary secretion.
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How is Bell’s palsy diagnosed?
5/18/2021 9:03 PM Oelshall
 Eyelid drooping and difficulty closing one (or
both) upper eyelids are classic findings in Belle’s
palsy.
 Asymmetric or
incomplete
smiles, decrease
in forehead
wrinkling, nasal
stuffiness, and
mild difficulty
with speaking are
also common
signs.
5/18/2021
 Frequent early
symptoms include
abrupt onset of dry
eye and tingling
around the mouth,
with progression to
more complete
facial palsy
occurring within one
to several days.
5/18/2021
Treatment
5/18/2021 9:03 PM Oelshall
 Systemic corticosteroids within the first few days
after the onset of paralysis.
 Combining steroids with antiherpetic drugs such as
acyclovir may decrease the severity and length of
paralysis.
 It is also helpful to protect the eye with lubricating
drops or ointment and a patch if eye closure is not
possible.
 In chronic condition, surgical decompression of the
nerve in the stylomastoid canal is effective
Disease of Nervous system
Frey’s auriculo-temporal syndrome
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Disease of Nervous system
Frey’s auriculo-temporal
syndrome
5/18/2021 9:03 PM Oelshall
Disease of Nervous system
In this condition there is
flushing and sweating of the skin
of the face innervated by the
auriculotemporal nerve whenever
salivation is stimulated
(gustatory sweating).
Frey’s auriculo-temporal syndrome
5/18/2021 9:03 PM Oelshall
Mandibular nerve
Auriculo-temporal
Disease of Nervous system
Paroted
glands
Sweat
glands
Periauricular &
temporal region
Sympathetic fibers
Etiology
5/18/2021 9:03 PM Oelshall
Surgery
Neoplasm
Inflammation
Damage of
auriculotemporal
nerve
In Parotid
Innervations of sweat
glands by the
parasympathetic
salivary fibers
Clinically
5/18/2021 9:03 PM Oelshall
 During eating:
Flushing, sweating and paroxysmal pain in
periauricular & temporal region
 Between attacks
Hyperesthesia or anesthesia of periauricular &
temporal region
5/18/2021 9:03 PM Oelshall
 Diagnosis:
Nerve block of auriculotemporal will relieve
symptoms.
 Treatment:
Sectioning of auriculotemporal nerve
Examples for Psychogenic pain
5/18/2021
Burning Mouth Syndrome
(Glossodynia)
Myo-fascial pain dysfunction
syndrome
5/18/2021 9:03 PM Oelshall
Psychogenic pain
Burning Mouth Syndrome
(Glossodynia)
Burning Mouth Syndrome
(Glossodynia)
5/18/2021 9:03 PM Oelshall
 The patient suffering from burning sensation
of mucosa without definitive causes
 Pain dose not follow anatomical pathway
 No lab. Findings
 No neurological findings
Psychogenic pain
Etiology
5/18/2021 9:03 PM Oelshall
The cause of BMS is unknown, but a number
of factors have been suspected such as:
1- Hormonal imbalance (postmenopausal)
2- Allergic reaction
3- Dry mouth
4- Chronic rubbing of mucosa
5- Psychogenic
CLINICAL MANIFESTATIONS
5/18/2021 9:03 PM Oelshall
 Women experience symptoms of BMS seven
times more frequently than men.
 Mainly complain at tongue, lips and cheek
 Burning intermittent or constant pain
 Diffuse pain, patient can not identify the site
of the pain
 Pain is relieved by eating drinking or chewing
 Normal oral mucosa or mild atrophic
 Depression symptoms, lack of appetite,
insomnia,
Diagnosis
5/18/2021 9:03 PM Oelshall
1- Exclusion of possibility of any oral or
dental lesions
2-Careful clinical examination & lab
investigation to detect undiagnosed anemia
3- If it unilateral, exam the cranial nerves.
5/18/2021 9:03 PM Oelshall
Myo-fascial pain
dysfunction syndrome
Psychogenic causes
5/18/2021 9:03 PM Oelshall
•MPD, or masticatory myalgia, is a
psychophysiologic disease that primarily
involves
the muscles of mastication and not the TMJ.
•Women are affected more frequently than
men.
5/18/2021
•MPD frequently is confused with painful conditions
affecting the TMJ, such as degenerative arthritis
or internal derangements,
•because patients with primary MPD can develop
these diseases secondarily, and patients with
primary joint disease can develop secondary MPD.
•Better understanding of the causes and
pathogenesis of this condition now makes its
diagnosis easier, however, and its treatment more
effective.
Myo-fascial pain dysfunction syndrome
5/18/2021 9:03 PM Oelshall
 It is a chronic disorder characterized by
Clicking
Trismus
Pain
+ Absence of pathologic abnormality of TMJ
Psychogenic causes
5/18/2021 9:03 PM Oelshall
 Stress seems to be an important factor in the
development of MPD.
 It is hypothesized that centrally induced
increases in muscle activity, frequently combined
with the presence of parafunctional habits such
as clenching or grinding of the teeth, result in
the associated muscle fatigue, pain, and
dysfunction.
 Similar symptoms also occasionally can result,
however, from muscle overextension, muscle
overcontraction, or trauma
5/18/2021 9:03 PM Oelshall
Etiology
5/18/2021 9:03 PM Oelshall
Muscle over
Extension Or Contraction
intermaxillary space over closure of mouth
Muscle fatigue
Oral habits due to psychic factors
Grinding clenching bruxism
5/18/2021 9:03 PM Oelshall
Altered chewing pattern
Chewing on one
side
Deviation of
bite to avoid
painful tooth
Malerupted
tooth
Muscle over
extension, over
contraction or
spasm
Sertonin,
histamin, kinin,
PG release
Inflammation
& pain
Clinically
5/18/2021 9:03 PM Oelshall
1-Unilateral pain
Pain over ear or periauricular area
Pain dull, sharp, pressure, burning as described by
the pts
Pain intensity: mild to sever
Pain may described as a vague pain affecting the
whole side of the face
Pain may radiate to forehead, occipital, temporal,
cervical region or the mandibular angel
Pain increased with tension, fatigue or chewing
5/18/2021 9:03 PM Oelshall
2-Active trigger point
Area of muscle that is tender on palpation
It include temporalis, masseter, digastric,
ptrygoid, sternomastoid
3-Deviation
Deviation of the jaw towards the affected
side on opening
Late clinical manifestations
5/18/2021 9:03 PM Oelshall
 Limitation of the jaw function
The patient cannot open his mouth widely
except with gentle pressure on lower jaw
 Clicking
detected by palpation
Treatment
5/18/2021 9:03 PM Oelshall
 Elimination of local factors (occlusal
adjustment)
 Bite raiser construction
 NSAI drugs. Ibuprofen 400mg tds
 Diazepam
 Muscle relaxant
 Moist heat application
 Muscle exercise
Thank youuuuuuuuu
For listening
Remember
Trigger points
Mention the Trigger points
at trigeminal neuralgia
Thank you

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Facial pain 2021 elshall converted

  • 1. Orofacial Pain Dr. Ossama El-Shall Part 1 of 2
  • 2. Pain 5/18/2021 9:03 PM Oelshall “An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.”
  • 3. Orofacial pain (OFP) is the presenting symptom of a broad spectrum of diseases 5/18/2021 9:03 PM Oelshall Disease of the oro-facial structures Generalized musculoskeletal or rheumatic disease Peripheral or CNS disease Psychological abnormality As a symptom, it may be due to The pain may be referred from other sources (eg. cervical muscles or intracranial pathology). or OFP may also occur in the absence of detectable physical, imaging, or laboratory abnormalities
  • 4. Cranial nerves responsible for orofacial pain 5/18/2021 9:03 PM Oelshall  Trigeminal nerve,(CN V) is the dominant nerve that relays sensory impulses from the orofacial area to the central nervous system.  Facial (CN VII),  Glossopharyngeal (CN IX),  Vagus (CN X) nerves
  • 5. Trigeminal nerve 5/18/2021 9:03 PM Oelshall  Skin of face,  Forehead and scalp  The top of the head  Conjunctiva and bulb of the eye  Oral and nasal mucosa  External aspect of the tympanic membrane  Teeth  Anterior two-thirds of tongue  Masticatory muscles  TMJ  Meninges of anterior and middle cranial fossae
  • 6. The most common facial pain disorder resulted from involvement of trigeminal nerve is Trigeminal neuralgia 5/18/2021
  • 7. 5/18/2021 9:03 PM Oelshall ▪ One disease affecting the trigeminal nerve is trigeminal neuralgia. ▪ A person experiencing trigeminal neuralgia may suffer an episode of facial pain that can last as long as two minutes. ▪ The cause of this disease is not currently known, but it may have to do with blood vessels putting pressure on the trigeminal nerve as it leaves the brain stem. trigeminal neuralgia
  • 8. Facial (CN VII) 5/18/2021 9:03 PM Oelshall
  • 10. 5/18/2021 9:03 PM Oelshall •Bell’s palsy is a weakness or paralysis of the muscles on one side of the face. •The facial nerve is often damaged by inflammation and causes one side of the face to droop. •Other symptoms of Bell’s palsy may be pain in or behind the ear, drooping, excessive tearing or dry eyes, numbness on one side of the face, or increased sensitivity to sound. Bell’s Palsy
  • 11. Glossopharyngeal (CN IX) 5/18/2021 9:03 PM Oelshall  Mucosa of the pharynx;  Palatine tonsils;  Posterior one-third of the tongue;  Internal surface of the tympanic membrane;  Skin of the external ear
  • 12. 5/18/2021 9:03 PM Oelshall
  • 13. 5/18/2021 9:03 PM Oelshall Glossopharyngeal Neuralgia Glossopharyngeal neuralgia is a condition believed to be caused by irritation of the 9th cranial nerve. In which there are repeated episodes of severe pain in the tongue, throat, ear, and tonsils, which can last from a few seconds to a few minutes.
  • 14. vagus (CN X) 5/18/2021 9:03 PM Oelshall  Skin at the back of the ear;  Posterior wall and floor of external auditory meatus.  Tympanic membrane.  Meninges of posterior cranial fossa.  Pharynx.  Larynx.
  • 15. 5/18/2021  The vagus nerve is one of the largest nerve systems in the body.  The name vagus is Latin for "wandering," which describes the long and complicated path this nerve takes through the body and all of the different systems it comes in contact with.  In some cases this nerve is linked to medical conditions such as low blood pressure, and in other cases doctors will stimulate this nerve to help treat disorders such as epilepsy.
  • 16. Classification of the pain 5/18/2021 9:03 PM Oelshall I- According to location II- According to origin
  • 17. I- According to location 5/18/2021 9:03 PM Oelshall 1- Neuritis Inflammation of nerve ending induced by chemical, microbial or toxic agents …..Burning sensation II- Neuralgia Paroxysmal pain along the course of the nerve III-Psychogenic No anatomical distribution, no clinical cause, not interfere with eating or sleeping
  • 18. II- According to origin 5/18/2021 9:03 PM Oelshall 1. Somatic pain 2. Neurogenous pain 3. Psychogenic pain 4. Referred pain 5. Vascular pain & headache.
  • 20. Somatic pain It resulting from stimulation of normal neural structures that innervates body tissue 5/18/2021 9:03 PM Oelshall Origin: Skin & MM Nature: Burning or pricking in nature Character: Localized Pts can identify its site For Example: Thermal pain: Pizza, hot instrument Chemical pin: aspirin burn Mechanical: traumatic ulcer Superfacial ulceration due to systemic disease eg; leukemia Superficial Deep
  • 21. Deep pain 5/18/2021 9:03 PM Oelshall joint Muscle Bone Collection of infected fluid in bone as in abscess OVER stretching or Contraction Rupture of some fibers TMJ
  • 22. Character of deep somatic pain 5/18/2021 9:03 PM Oelshall 1- Bone pain will be throbbing in nature 2- May be referred involve area supplied with the same sensory nerve 3- Muscle and joint pain: dull aching in nature. 4- Patient can hardly identify the source of the pain.
  • 23. II- According to origin 5/18/2021 9:03 PM Oelshall 1. Somatic pain 2. Neurogenous pain 3. Psychogenic pain 4. Referred pain 5. Vascular pain & headache.
  • 25. Neurogenous pain 1-Trigeminal neuralgia 2-Glossopharyngeal n. Paroxysmal 3-Occipital neuralgia. 4- Post herpetic neuralgia 5- Post traumatic pain 6- Atypical odontalgia Non paroxysmal 7- Bell’s palsy 8- Frey’s auriculo-temporal syndrome 5/18/2021 9:03 PM Oelshall
  • 26. II- According to origin 5/18/2021 9:03 PM Oelshall 1. Somatic pain 2. Neurogenous pain 3. Psychogenic pain 4. Referred pain 5. Vascular pain & headache.
  • 28. Psychogenic pain 5/18/2021 9:03 PM Oelshall 1- Burning mouth syndrome 2- Atypical orofacial pain 3- Myofacial pain dysfunction syndrome
  • 29. II- According to origin 5/18/2021 9:03 PM Oelshall 1. Somatic pain 2. Neurogenous pain 3. Psychogenic pain 4. Referred pain 5. Vascular pain & headache.
  • 31. Referred pain  Is pain that perceived at a location other than the site of the painful stimulus.  An example is the case of angina pectoris brought on by a myocardial infarction, where pain is often felt in the neck, shoulders, and back rather than in the thorax (chest), the site of the injury  Referred pain is not felt at the site of disease but felt at distance site  Radiating pain is the extension of pain from original site to another site with persistance of pain at original site 5/18/2021
  • 32. II- According to origin 5/18/2021 9:03 PM Oelshall 1. Somatic pain 2. Neurogenous pain 3. Psychogenic pain 4. Referred pain 5. Vascular pain & headache.
  • 33. Vascular pain & headache
  • 34. Vascular pain & headache. 5/18/2021 9:03 PM Oelshall 1-Tension Headache 2-Migraine. 3-Cluster headache. 4-Cranial arteritis.
  • 35. Tension headache  A tension headache is the most common type of headache.  It can cause mild, moderate, or intense pain behind your eyes and in your head and neck.  Some people say that a tension headache feels like a tight band around their forehead.  Most people who experience tension headaches have episodic headaches 5/18/2021
  • 36. Migraine  Migraine is a neurological condition that can cause multiple symptoms.  It's frequently characterized by intense, debilitating headaches.  Symptoms may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.  Migraines often run in families and affect all ages 5/18/2021
  • 37. Cluster headache  Cluster headache (CH) is a neurological disorder characterized by recurrent severe headaches on one side of the head, typically around the eye.  There is often accompanying eye watering, nasal congestion, or swelling around the eye on the affected side.  These symptoms typically last 15 minutes to 3 hours 5/18/2021
  • 39. Cranial arteritis.  Or Temporal arteritis is a form of vasculitis (inflammation of the blood vessels) in temporal arteries.  Also known as giant cell arteritis or Horton's arteritis  Frequently it causes headaches, scalp tenderness, jaw pain and vision problems. Untreated, it can lead to blindness. 5/18/2021
  • 42. Facial Neuralgias 5/18/2021 9:03 PM Oelshall The classic neuralgias that affect the craniofacial region are a unique group of neurologic disorders involving the cranial nerves and are characterized by II.Neurogenous pain Brief episodes of shooting, often electric shock– like pain along the course of the affected nerve branch. pain-free periods between attacks and refractory periods immediately after an attack, during which a new episode cannot be triggered trigger zones on the skin or mucosa that precipitate painful attacks when touched.
  • 43. 5/18/2021 9:03 PM Oelshall These clinical characteristics differ from neuropathic pain, which tends to be - constant - has a burning quality - without the presence of trigger zones. II.Neurogenous pain
  • 44. Facial Neuralgias resulting in Neurogenous pain 1-Trigeminal neuralgia 2-Glossopharyngeal n. Paroxysmal 4- Post herpetic neuralgia 5- Post traumatic pain 6- Atypical odontalgia Non paroxysmal 7- Bell’s palsy 8- Frey’s auriculo-temporal syndrome 5/18/2021 9:03 PM Oelshall
  • 45. TRIGEMINAL NEURALGIA tic douloureux 5/18/2021 9:03 PM Oelshall II.Neurogenous pain People with this pain often twitch, which is where trigeminal neuralgia gets its French nickname 'tic douloureux’, meaning "painful twitch”.
  • 46. TRIGEMINAL NEURALGIA tic douloureux 5/18/2021 9:03 PM Oelshall It is a sharp sever paroxysmal pain along the course of trigeminal nerve with un-definitive etiology It is the most common of the cranial neuralgias • Chiefly affects individuals older than 50 years of age. When younger individuals are involved, suspicion of a detectable underlying lesion such as a tumor, an aneurysm, or multiple sclerosis must be increased. II.Neurogenous pain
  • 47. Etiology and Pathogenesis. 5/18/2021 9:03 PM Oelshall The cause of the majority of cases of TN remains controversial, but approximately 10% of cases have detectable underlying pathology such as: 1- Tumor of the cerebellar pontine angle, 2- Multiple sclerosis, MS 3- A vascular malformation. The remainder of cases of TN (90%) are classified as idiopathic. Several theories exist regarding the etiology of TN. II.Neurogenous pain
  • 49. 5/18/2021 9:03 PM Oelshall  The most widely accepted theory is that a majority of cases of TN are caused by an atherosclerotic blood vessel (usually the superior cerebellar artery) pressing on and grooving the root of the trigeminal nerve.  This pressure results in focal demyelinization and hyperexcitability of nerve fibers, which will then fire in response to light touch, resulting in brief episodes of intense pain. II.Neurogenous pain
  • 51. 5/18/2021 9:03 PM Oelshall  Evidence for this theory includes the observation that neurosurgery that removes the pressure of the vessel from the nerve root by use of a microvascular decompression procedure eliminates the pain in a majority of cases. II.Neurogenous pain
  • 52. 5/18/2021 9:03 PM Oelshall  Additional evidence for this theory was obtained from a study using tomographic magnetic resonance imaging (MRI), which showed that contact between a blood vessel and the trigeminal nerve root was much greater on the affected side.
  • 53. 5/18/2021 MRI can detect blood vessels (arrow) that may be compressing the trigeminal nerve
  • 54. Clinical Features 5/18/2021 9:03 PM Oelshall The majority of patients with TN present with characteristic clinical features, which include episodes of intense shooting stabbing pain that lasts for a few seconds and then completely disappears. The pain has an electric shock–like quality and is unilateral except in a small percentage of cases. The maxillary branch is the branch that is most commonly affected, followed by the mandibular branch and (rarely) the ophthalmic branch. Involvement of more than one branch occurs in some cases. II.Neurogenous pain
  • 55. 5/18/2021 9:03 PM Oelshall  Pain in TN is precipitated by light touch on a “trigger zone” present on the skin or mucosa within the distribution of the involved nerve branch.  Common sites for trigger zones include the nasolabial fold and the corner of the lip. II.Neurogenous pain
  • 56. TRIGGER FACTORS Touching Washing of face Shaving Teeth cleaning Cold breeze Eating Talking Application of lotions and cosmetics patients often protect the trigger zone with their hand or an article of clothing.
  • 57. 5/18/2021 9:03 PM Oelshall  Intraoral trigger zones can confuse the diagnosis by suggesting a dental disorder, and TN patients often first consult a dentist for evaluation.
  • 59. 5/18/2021 9:03 PM Oelshall  Just after an attack, there is a refractory period when touching the trigger zone will not precipitate pain.  The number of attacks may vary from one or two per day to several per minute.
  • 60. 5/18/2021 9:03 PM Oelshall  Half an inch finger sign: The patient points to the trigger area with his finger away by half an inch to avoid touching it. II.Neurogenous pain
  • 61. 5/18/2021 9:03 PM Oelshall Diagnosis.  The diagnosis is based on the history of shooting pain along a branch of the trigeminal nerve, precipitated by touching a trigger zone, and possibly examination that demonstrates the shooting pain.  A routine cranial nerve examination will be normal in patients with idiopathic TN, but sensory and/or motor changes may be evident in patients with underlying tumors or other CNS pathology. II.Neurogenous pain
  • 62. 5/18/2021 9:03 PM Oelshall  Local anesthetic blocks, which temporarily eliminate the trigger zone, may also be helpful in diagnosis.  Since approximately 10% of TN cases are caused by detectable underlying pathology, enhanced MRI of the brain is indicated to rule out tumors, multiple sclerosis, and vascular malformations.
  • 66. Mechanism of action of anticonvulsants, antiepileptic or antiseizure drugs)  Anticonvulsants suppress the excessive rapid firing of neurons during seizures.  Anticonvulsants also prevent the spread of the seizure within the brain.  Conventional antiepileptic drugs may block sodium channels or enhance γ- aminobutyric acid (GABA) function. 5/18/2021
  • 67.  Several antiepileptic drugs have multiple or uncertain mechanisms of action.  Next to the voltage-gated sodium channels and components of the GABA system, their targets include GABAA receptors, the GAT-1 GABA transporter, and GABA transaminase.  Additional targets include voltage- gated calcium channels, SV2A, and α2δ.  By blocking sodium or calcium channels, antiepileptic drugs reduce the release of excitatory glutamate, whose release is considered to be elevated in epilepsy, but also that of GABA. 5/18/2021
  • 68.  This is probably a side effect or even the actual mechanism of action for some antiepileptic drugs, since GABA can itself, directly or indirectly, act proconvulsively.  Another potential target of antiepileptic drugs is the peroxisome proliferator- activated receptor alpha. 5/18/2021
  • 69. 5/18/2021 9:03 PM Oelshall Since TN may have temporary or permanent spontaneous remissions, drug therapy should be slowly withdrawn if a patient remains pain free for 3 months.
  • 70. 5/18/2021 9:03 PM Oelshall  Clinicians treating TN must be aware that drug therapy often becomes less effective over time and that progressively higher doses may be required for pain control.  In cases in which drug therapy is ineffective or in which the patient is unable to tolerate the side effects of drugs after trials of several agents, surgical therapy is indicated. II.Neurogenous pain 2. Surgical
  • 71. SURGICAL 1. Injection of phenol or alcohol into a trigeminal ganglion 2. Radiofrequency coagulation of a branch 3. Sectioning of sensory root of trigeminal ganglion inside the cranium 4. Microvascular decompression
  • 72. PREVENTION While the condition itself can't be prevented, there are a number of things patients can do to avoid triggering attacks:  Wash with cotton pads and warm water over the face  Rinse the mouth with water after eating, if tooth- brushing triggers pain  Eat and drink food and beverages at room temperature  Chew on the unaffected side  Eat soft foods, if eating is becoming a problem
  • 73. POSTHERPETIC NEURALGIA 5/18/2021 9:03 PM Oelshall II.Neurogenous pain
  • 74. POSTHERPETIC NEURALGIA 5/18/2021 9:03 PM Oelshall  Etiology and Pathogenesis. Herpes zoster, is caused by the reactivation of latent varicella-zoster virus that results in both pain and vesicular lesions along the course of the affected nerve. Approximately 15 to 20% of cases of herpes zoster involve the trigeminal nerve although the majority of these cases affect the ophthalmic division of the fifth nerve, resulting in pain and lesions in the region of the eyes and forehead. II.Neurogenous pain
  • 75. 5/18/2021 9:03 PM Oelshall Herpes zoster of the maxillary and mandibular divisions is a cause of facial and oral pain as well as of lesions. In a majority of cases, the pain of herpes zoster resolves within a month after the lesions heal. Pain that persists longer than a month is classified as postherpetic neuralgia (PHN) although some authors do not make the diagnosis of PHN until the pain has persisted for longer than 3 or even 6 months. II.Neurogenous pain
  • 76. 5/18/2021 9:03 PM Oelshall  PHN may occur at any age, but the major risk factor is increasing age.  Elderly patients also have an increased risk of experiencing severe pain for an extended period of time. II.Neurogenous pain
  • 77. 5/18/2021 9:03 PM Oelshall Clinical Manifestations. Patients with PHN experience persistent pain, paresthesia, hyperesthesia, and allodynia months to years after the zoster lesions have healed. The pain is often accompanied by a sensory deficit, and there is a correlation between the degree of sensory deficit and the severity of pain. II.Neurogenous pain
  • 78. 5/18/2021 9:03 PM Oelshall Management.  Many treatment options are available for the management of PHN, and the method chosen should depend on the severity of the symptoms as well as the general medical status of the patient.  Treatment includes topical and systemic, drug therapy and surgery. II.Neurogenous pain
  • 79. 5/18/2021 9:03 PM Oelshall  Topical therapy includes the use of topical anesthetic agents, such as lidocaine, or analgesics, particularly capsaicin.  Lidocaine used either topically or injected gives short-term relief from severe pain.  Capsaicin, an extract of hot chili peppers that depletes the neurotransmitter substance when used topically, has been shown to be helpful in reducing the pain of PHN, but the side effect of a burning sensation at the site of application limits its usefulness for many patients. II.Neurogenous pain
  • 80. 5/18/2021 9:03 PM Oelshall  The use of tricyclic antidepressants is a well- established method of reducing the chronic burning pain that is characteristic of PHN.  Because a significant number of elderly patients cannot tolerate the sedative or cardiovascular side effects associated with tricyclic antidepressants, the use of other drugs, particularly gabapentin, has been advocated. II.Neurogenous pain
  • 81. 5/18/2021 9:03 PM Oelshall  When medical therapy has been ineffective in managing intractable pain, nerve blocks or surgery at the level of the peripheral nerve or dorsal root have been effective for some patients.  The best therapy for PHN is prevention. There is evidence that the use of antiviral drugs, particularly famciclovir, along with a short course of systemic corticosteroids during the acute phase of the disease may decrease the incidence and severity of PHN II.Neurogenous pain
  • 82. 5/18/2021 9:03 PM Oelshall II.Neurogenous pain Glossopharyngeal Neuralgia
  • 83. 5/18/2021 9:03 PM Oelshall Glossopharyngeal Neuralgia Glossopharyngeal neuralgia is a condition believed to be caused by irritation of the 9th cranial nerve. In which there are repeated episodes of severe pain in the tongue, throat, ear, and tonsils, which can last from a few seconds to a few minutes.
  • 85. Orofacial Pain Dr. Ossama El-Shall Part 2 of 2
  • 86. POST-TRAUMATIC NEUROPATHIC PAIN 5/18/2021 9:03 PM Oelshall II.Neurogenous pain
  • 87. POST-TRAUMATIC NEUROPATHIC PAIN 5/18/2021 9:03 PM Oelshall Etiology and Pathogenesis.  Trigeminal nerve injuries may result from facial trauma or surgical procedures, such as the removal of impacted third molars, the placement of dental implants, the removal of cysts or tumors of the jaws, or osteotomies.  In some individuals, nerve injury results only in numbness whereas others experience pain that may be either spontaneous or triggered by a stimulus.  The pain associated with nerve injury often has a burning quality. II.Neurogenous pain
  • 88. 5/18/2021 9:03 PM Oelshall Total nerve section (neurotmesis) Frequently causes permanent nerve damage, resulting in anesthesia and/or dysesthesia. Nerve injuries Minor nerve injuries (neurapraxia) Do not result in axonal degeneration but may cause temporary symptoms of parasthesia for a few hours or days. Serious nerve damage (axonotmesis) Results in the degeneration of neural fibers although the nerve trunk remains intact. It cause symptoms for several months but have a good prognosis for recovery after axonal regeneration is complete.
  • 90. Manifestation 5/18/2021 9:03 PM Oelshall Patients with nerve damage may experience persistent burning pain arising from trauma plus: II.Neurogenous pain Anesthesia=loss of sensation Paraesthesia=feeling of pins and needles Allodynia=Pain by non painful stimuli Hyperalgesia=Exaggerated response to mild painful stimuli
  • 91. Treatment 5/18/2021 9:03 PM Oelshall  Systemic steroids during 1st week of trauma  Narcotic analgesic  Topical capsaicin  Tricyclic antidepressant II.Neurogenous pain
  • 92. Bell’s palsy 5/18/2021 9:03 PM Oelshall II.Neurogenous pain
  • 93. 5/18/2021 9:03 PM Oelshall It is peripheral facial weakness of unknown etiology affecting any age group of either sex. How did Bell’s palsy get its name? Sir Charles Bell was a Scottish surgeon who described the nerve supply to the facial muscles over 200 years ago. Bell’s palsy II.Neurogenous pain
  • 94. 5/18/2021 9:03 PM Oelshall  Bell’s palsy is recognized as a unilateral paralysis of the facial nerve.  The dysfunction has been attributed to an inflammatory reaction involving the facial nerve.  A relationship has been demonstrated between Bell’s palsy and the isolation of herpes simplex virus 1 from nerve tissues.  Bell’s palsy must be differentiated from other causes of facial nerve paralysis, such as herpes zoster of the geniculate ganglion (Ramsay Hunt syndrome).
  • 95. Pathogenesis of Bell’s palsy 5/18/2021 9:03 PM Oelshall Geneculate ganglion Stylomastoid foramen Facial nerve Petrosal artery Stylomastoid artery Fibrous C T Middle meningeal External carotid Inflammation of Facial nerve inside the canal demyelination & edema loss blood supply II.Neurogenous pain
  • 96. 5/18/2021 9:03 PM Oelshall  Its etiology is unknown and there is no local or systemic causes can be identified.  It may be immunologically mediated or associated with infection especially viral infection II.Neurogenous pain
  • 98. Clinically 5/18/2021 9:03 PM Oelshall  Very rapid onset, patient may wake up with facial paralysis  Bell’s palsy begins with slight pain around one ear and along the mandibular angle, followed by an abrupt paralysis of the muscles on that side of the face.  The eye on the affected side stays open, the corner of the mouth drops.  As a result of masseter weakness, food is retained in both the upper and lower buccal and labial folds.  The facial expression changes remarkably.  Due to impaired blinking, corneal ulcerations from foreign bodies can occur.  Involvement of the chorda tympani nerve leads to loss of taste sensation on the anterior two-thirds of the tongue and reduced salivary secretion.
  • 99. 5/18/2021 9:03 PM Oelshall How is Bell’s palsy diagnosed?
  • 100. 5/18/2021 9:03 PM Oelshall  Eyelid drooping and difficulty closing one (or both) upper eyelids are classic findings in Belle’s palsy.
  • 101.  Asymmetric or incomplete smiles, decrease in forehead wrinkling, nasal stuffiness, and mild difficulty with speaking are also common signs. 5/18/2021
  • 102.  Frequent early symptoms include abrupt onset of dry eye and tingling around the mouth, with progression to more complete facial palsy occurring within one to several days. 5/18/2021
  • 103. Treatment 5/18/2021 9:03 PM Oelshall  Systemic corticosteroids within the first few days after the onset of paralysis.  Combining steroids with antiherpetic drugs such as acyclovir may decrease the severity and length of paralysis.  It is also helpful to protect the eye with lubricating drops or ointment and a patch if eye closure is not possible.  In chronic condition, surgical decompression of the nerve in the stylomastoid canal is effective Disease of Nervous system
  • 104. Frey’s auriculo-temporal syndrome 5/18/2021 9:03 PM Oelshall Disease of Nervous system
  • 105. Frey’s auriculo-temporal syndrome 5/18/2021 9:03 PM Oelshall Disease of Nervous system In this condition there is flushing and sweating of the skin of the face innervated by the auriculotemporal nerve whenever salivation is stimulated (gustatory sweating).
  • 106. Frey’s auriculo-temporal syndrome 5/18/2021 9:03 PM Oelshall Mandibular nerve Auriculo-temporal Disease of Nervous system Paroted glands Sweat glands Periauricular & temporal region Sympathetic fibers
  • 107. Etiology 5/18/2021 9:03 PM Oelshall Surgery Neoplasm Inflammation Damage of auriculotemporal nerve In Parotid Innervations of sweat glands by the parasympathetic salivary fibers
  • 108. Clinically 5/18/2021 9:03 PM Oelshall  During eating: Flushing, sweating and paroxysmal pain in periauricular & temporal region  Between attacks Hyperesthesia or anesthesia of periauricular & temporal region
  • 109. 5/18/2021 9:03 PM Oelshall  Diagnosis: Nerve block of auriculotemporal will relieve symptoms.  Treatment: Sectioning of auriculotemporal nerve
  • 110. Examples for Psychogenic pain 5/18/2021 Burning Mouth Syndrome (Glossodynia) Myo-fascial pain dysfunction syndrome
  • 111. 5/18/2021 9:03 PM Oelshall Psychogenic pain Burning Mouth Syndrome (Glossodynia)
  • 112. Burning Mouth Syndrome (Glossodynia) 5/18/2021 9:03 PM Oelshall  The patient suffering from burning sensation of mucosa without definitive causes  Pain dose not follow anatomical pathway  No lab. Findings  No neurological findings Psychogenic pain
  • 113. Etiology 5/18/2021 9:03 PM Oelshall The cause of BMS is unknown, but a number of factors have been suspected such as: 1- Hormonal imbalance (postmenopausal) 2- Allergic reaction 3- Dry mouth 4- Chronic rubbing of mucosa 5- Psychogenic
  • 114. CLINICAL MANIFESTATIONS 5/18/2021 9:03 PM Oelshall  Women experience symptoms of BMS seven times more frequently than men.  Mainly complain at tongue, lips and cheek  Burning intermittent or constant pain  Diffuse pain, patient can not identify the site of the pain  Pain is relieved by eating drinking or chewing  Normal oral mucosa or mild atrophic  Depression symptoms, lack of appetite, insomnia,
  • 115. Diagnosis 5/18/2021 9:03 PM Oelshall 1- Exclusion of possibility of any oral or dental lesions 2-Careful clinical examination & lab investigation to detect undiagnosed anemia 3- If it unilateral, exam the cranial nerves.
  • 116. 5/18/2021 9:03 PM Oelshall Myo-fascial pain dysfunction syndrome Psychogenic causes
  • 117. 5/18/2021 9:03 PM Oelshall •MPD, or masticatory myalgia, is a psychophysiologic disease that primarily involves the muscles of mastication and not the TMJ. •Women are affected more frequently than men.
  • 118. 5/18/2021 •MPD frequently is confused with painful conditions affecting the TMJ, such as degenerative arthritis or internal derangements, •because patients with primary MPD can develop these diseases secondarily, and patients with primary joint disease can develop secondary MPD. •Better understanding of the causes and pathogenesis of this condition now makes its diagnosis easier, however, and its treatment more effective.
  • 119. Myo-fascial pain dysfunction syndrome 5/18/2021 9:03 PM Oelshall  It is a chronic disorder characterized by Clicking Trismus Pain + Absence of pathologic abnormality of TMJ Psychogenic causes
  • 120. 5/18/2021 9:03 PM Oelshall  Stress seems to be an important factor in the development of MPD.  It is hypothesized that centrally induced increases in muscle activity, frequently combined with the presence of parafunctional habits such as clenching or grinding of the teeth, result in the associated muscle fatigue, pain, and dysfunction.  Similar symptoms also occasionally can result, however, from muscle overextension, muscle overcontraction, or trauma
  • 121. 5/18/2021 9:03 PM Oelshall
  • 122. Etiology 5/18/2021 9:03 PM Oelshall Muscle over Extension Or Contraction intermaxillary space over closure of mouth Muscle fatigue Oral habits due to psychic factors Grinding clenching bruxism
  • 123. 5/18/2021 9:03 PM Oelshall Altered chewing pattern Chewing on one side Deviation of bite to avoid painful tooth Malerupted tooth Muscle over extension, over contraction or spasm Sertonin, histamin, kinin, PG release Inflammation & pain
  • 124. Clinically 5/18/2021 9:03 PM Oelshall 1-Unilateral pain Pain over ear or periauricular area Pain dull, sharp, pressure, burning as described by the pts Pain intensity: mild to sever Pain may described as a vague pain affecting the whole side of the face Pain may radiate to forehead, occipital, temporal, cervical region or the mandibular angel Pain increased with tension, fatigue or chewing
  • 125. 5/18/2021 9:03 PM Oelshall 2-Active trigger point Area of muscle that is tender on palpation It include temporalis, masseter, digastric, ptrygoid, sternomastoid 3-Deviation Deviation of the jaw towards the affected side on opening
  • 126. Late clinical manifestations 5/18/2021 9:03 PM Oelshall  Limitation of the jaw function The patient cannot open his mouth widely except with gentle pressure on lower jaw  Clicking detected by palpation
  • 127. Treatment 5/18/2021 9:03 PM Oelshall  Elimination of local factors (occlusal adjustment)  Bite raiser construction  NSAI drugs. Ibuprofen 400mg tds  Diazepam  Muscle relaxant  Moist heat application  Muscle exercise
  • 131. Mention the Trigger points at trigeminal neuralgia