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25 January 2022: Webinar on Adverse Outcome Pathway co-operative activities between scientific journals and the OECD
The document outlines the importance of collaborative efforts between scientific journals, regulatory bodies, and policy makers to enhance the impact of science on decision-making, particularly through the Adverse Outcome Pathway (AOP) framework. It describes a workshop held in June 2021 focused on strategies for communication, collaboration, and technical support among various stakeholders in the life sciences community. Ongoing and planned activities aim to address challenges in the current publishing paradigm and promote better engagement between scientists and decision-makers.
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25 January 2022: Webinar on Adverse Outcome Pathway co-operative activities between scientific journals and the OECD
- 1. 1 Clemens Wittwehr European Commission– Joint Research Centre (JRC) Webinar on Adverse Outcome Pathway (AOPs) co-operative activities between Scientific journals and the OECD 25 January 2022 The importance of collaboration Science with impact in an era of information overload
- 2. 2 Global scientific output (indicatedby the increased rate of papers published in scientific journals that are accessible to a broader range of scientists through world wide web infrastructures) Issue Uptake of science in decision-making contexts where science should have its greatest impact
- 3. 3 Co-ordination group from Weneeded a workshop! Invitees from American Chemical Society (ACS) American Society of Cellular and Computational Toxicology (ASCCT) Danish National Food Institute Elsevier Endocrine Society European Infrastructure for Translational Medicine (EATRIS) European Society of Toxicology In Vitro (ESTIV) European Teratology Society (ETS) EUROTOX Frontiers Health and Human Services (HHS), Food and Drug Administration (FDA) Health Canada Karolinska Institutet National Institute of Health Sciences Nowegian Institute for Water Research RTI International Society of Environmental Toxicology and Chemistry (SETAC) - Europe Society of Toxicology (SOT) Swiss Centre for Applied Human Toxicology U.S. Army Corps of Engineers (USACE), Engineer Research and Development Center (ERDC) University Antwerpen
- 4. 4 • Firstly, knowledgemanagement is the essential linkage that connects science with its potential impacts more efficiently. The Adverse Outcomes Pathway (AOP) Framework was proposed as one example of a form of knowledge management that deliberately sets out to gather, synthesise and organise knowledge about toxicology in such a way as to make it more easily actionable by regulatory bodies and policy makers. • Secondly, the idea that professional life sciences societies and their affiliated journals play a pivotal role in enabling the forms of co-operation and collaboration required for a closer relationship to be forged between scientists and decision-makers across disciplines, domains, and sectors. Premises
- 5. 5 • Three afternoons,7-9 June 2021 • Biosketches • Introductory talks • AOP perspective • Interactive breakout sessions • Slido polls • Coordination group prepares workshop report (ongoing) Format
- 6. 6 Strand 3 Technical Implementation andSupport Strand 1 Communication, collaboration and shared understanding Instigated by a “champion” (from the workshop) Science with impact in an era of information overload Workshop 7-9 June 2021 Collection of problems and proposed solutions List of possible actions
- 7. 7 Strand 1 -Communication, collaboration and shared understanding Ongoing activities • AOP Framework analysis Planned activities • Society conferences and similar events • Identify training opportunities and training content • Pellston workshops • Tracking the science that impacts decisions • On-going engagement of scientists and policy-makers
- 8. 8 Strand 3 –Technical implementation and support Ongoing activities • AOP-Wiki FAIRness • Tagging of information in the AOP- Wiki • Update of the AOP-Wiki data model • Describing and sharing knowledge about test methods and protocols Planned activities • Nano-publications • Pellston workshops • Topical policy app to provide concise, high quality summaries • Current publishing paradigms, knowledge tagging, FAIR principles
- 9. 9 Strand 3 Technical Implementation andSupport Strand 1 Communication, collaboration and shared understanding Strand 2 Engagement with publishers Instigated by a “champion” (from the workshop) Science with impact in an era of information overload Workshop 7-9 June 2021 Collection of problems and proposed solutions List of possible actions
- 10. 10 Strand 2 -Engagement with publishers AOP • Current publishing paradigm does not really reward AOP-Wiki submissions • AOP-Wiki review process often bottleneck to more wide-spread use ? ?
- 11. 11 Strand 2 -Engagement with publishers AOP Journal • Parallel publication can address review and recognition issue ! !
- 12. 12 Strand 2 -Engagement with publishers AOP Journal • First journals: • Environmental Toxicology and Chemistry • Environmental and Molecular Mutagenesis
- 13. 13 Strand 3 Technical Implementation andSupport Strand 1 Communication, collaboration and shared understanding Strand 2 Engagement with publishers Instigated by a “champion” (from the workshop) Loose observation Future Actions Other trigger Science with impact in an era of information overload Workshop 7-9 June 2021 Collection of problems and proposed solutions List of possible actions
- 14. 14 • Identify championsfor follow-up actions • Instigate these follow-up actions • This OECD activity • Pellston workshops on a well-defined topics Next steps Strand 1 Communication, collaboration and shared understanding Strand 3 Technical Implementation and Support Strand 2 Engagement with publishers • Tracking the science that impacts decisions • On-going engagement of scientists and policy- makers • Topical policy app to provide concise, high quality summaries • Current publishing paradigms, knowledge tagging, FAIR principles
- 15. 15 Stay in touch •EUScience Hub: ec.europa.eu/jrc •Twitter: @EU_ScienceHub •Facebook: EU Science Hub - Joint Research Centre •LinkedIn: Joint Research Centre •YouTube: EU Science Hub