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Emergency management of oral
and maxillofacial trauma
including prophylactic
antibiotherapy.
Dr. NDAYISHIMIYE Samuel
Dental Surgeon.
OUTLINES
• Introduction
• Etiology of oral and maxillofacial trauma
• Assessment of patient with OMF trauma
• Soft tissues trauma
• Mandible fracture and emergency management
• Midface fractures and emergency management
• Dental trauma
• Complications of oral and maxillofacial trauma
• Prophylactic ntibiotherrapy
• References
Introduction
• What is tissue trauma?
• Is the damage of tissues by physical , thermal, chemicals agents.
• When do we say maxillofacial trauma is an emergency?
• Airway compromise
• Brain injury
• C-spine injury
• Avulsion of tissues.
Introduction contd..
• Oral and maxillofacial region is crucial area that serves in Airway , esthetic,
mastication and speech.
• Facial injuries deserve special attention because of their complications and
esthetic significance.
• Facial trauma are life threatening because of airway compromise, bleeding,
and infections.
• injury causes include moto-vehicle accidents ,falls, sports, fights, and
domestic violence.
• Facial trauma is among the common causes of maxillofacial emergencies
• May be associated with other life threatening injury like C-spine, brain
injury and extremities..
Etiology of OMF trauma
• Most of cause of the injuries include moto-vehicle , accidents ,falls, sports,
fights, and domestic violence.
• Motorcycle(24.7%)
• Moto-car(20.9%)
• Fall accident(17.6%)
• Bicycle(14.3%)
• Assault(7.7%)
• Domestic violence(7.1%)
• Sports accident(5.5%)
• Others(2.2%)
Classification of oral and maxillofacial injuries
Soft tissues trauma
Abrasions
Contusions
Echymosis
Lacerations
avulsion
Hard tissues trauma
fractures
Upper face fractures
Mid-face fractures
Lower face fractures
Displacement
dislocations
Teeth and dento-alveolar
injuries.
Emergency management of OMF Trauma
• emergency management of oral and maxillofacial trauma patient requires
advanced trauma life support(ATLS)
• Triage
• Primary survey
• Resuscitation
• Adjunct to primary survey
• ABCDE
• Secondary survey
• Adjunct to secondary survey
• Definitive care
Emergency management contd,……
• Secondary survey(AMPLE)
Head to toe examination
Allergy
Medications
Past illness/pregnancy
Last meal
Exposure/event.
• Triage: who is more critical?
based on ABC priorities.
Primary survey:
Airway and C spine protection.
Breathing and Ventilation
Circulation with hemorrhage
control
Disability (neurological status GCS,
sensation, movement and motor
power)
Exposure/environmental control.
Emergency management contd,……
• Airway
• Call the patient if not responding consider
the Airway to be compromised.
• Inspect for foreign body, facial,
mandibular, laryngeal or tracheal fracture.
• Suction of all clots, and secretions.
• Jaw-thrust or chin-lift maneuver to open
airways.
• Oro-tracheal intubation for unconscious
without gag reflex.
• Prevent excessive movement of C spine
• Might have C spine injury.
• C collar placement.
• Breathing and ventilation
• Ensure chest expansion
• Pulse oximeter to see hemoglobin
saturation.
• Look for signs of tension pneumothorax,
massive hemothorax,open
pneumothorax, tracheal or laryngeal
injuries.
• Supplemental oxygen
• tension pneumothorax affect both
respiration and circulation
• Needle decompression
Emergency management contd,……
• Areas of tension pneumothorax needle decompression, jaw thrust
and chin lift for airway and breathing management
Emergency management contd,……
• Circulation
• Assess cardiac output and bleeding.
• Quick identification and control of
hemorrhage is crucial.
• If tension pneumothorax is excluded,
hypotension is the cause of chock until
proven otherwise.
• 3 elements of CO assessment
• Level of consciousness: stable/altered
• Skin perfusion : pink face, extremities/gray
facial skin/pale and cold extremities.
• Pulse: rapid thread, absent central pulse point
for immediate need of resuscitation.
• External bleeding has to be controlled by
direct pressure on wound. Tourniquet may be
applied if direct pressure on extremity is not
effective.
• Major areas of internal bleeding are chest,
abdomen , retroperitoneum, pelvis and long
bones.
• Use of imaging helps. Chest x-ray, pelvic x-ray,
FAST(focused assessment with sonography for
trauma)
• Replacement of intravascular volume.
Emergency management contd,……
• Disability
• GCS
• Pupillary size and reaction
• Determine spinal cord injury level
• Decreased consciousness may indicate
Brain hypoxia,
 hypo-perfusion ,
 hypoglycemia,
direct cerebral injury
• Adequate oxygenation and perfusion to prevent secondary brain injury
Emergency management contd,……
• Exposure and environmental control
removal of garments for thorough examination
Cover with blanket to prevent hypothermia
Warm IV fluids to the body temperature.
Emergency management contd,……
• Secondary survey(AMPLE)
Head to toe examination
Allergy
Medications
Past illness/pregnancy
Last meal
Exposure/event.
Assessment of patient with OMF trauma
• History of mechanism of injury is the key(from the patient or
whiteness who were at the scene if patient is unconscious)
• Examination should be quick and proper.
• Begin with overall inspection noting any facial
asymmetries,wound,hemorrhage,serous discharge and ecchymosis.
• Neurological examination of 12 CN.
• Assessment of sensory nerves(ophthalmic , maxillary and
mandibular.)
Assessment cont’d,..
• Soft tissues injuries
• Lips(through band through lacerations)
• Facial symmetry
• Occlusion : disturbed in maxillofacial fractures.
• Peri-orbital and conjuctival ecchymosis,
• Palatal and sublingual hematoma
• CSF leakage(rhinorrhea, otorrhea)
• Tenderness in facial area
• Step deformity
• Respiration pattern
• C spine dermatomes.
Soft tissues injuries and their management
• Hematoma:
 is localized collection of the blood in
subcutaneous, intramuscularly or submucosal.
 Most are reabsorbed
 Persistent ones may require incision and drainage.
 Antibiotic cover for prevention of hematoma
infection.
• Abrasions:
 friction between an object and soft tissue surface.
 Epidermis involved but sometimes deeper layers’
 Painful.
 Mngt: clean and irrigate with saline
 Foreign body removal.
 Topical antibiotics
• Contusion:
 due to blow or fall against hard and brunt object.
 Blood extravasation from subcutaneous or
submucosa causing bruises.
 Look for the osseous trauma!!!
 Mgt: ice pack.
Soft tissues injuries and their management
• Lacerated and avulsive wound
Most frequently accoutered type of wound.
Vehicle accidents, Low velocity missiles or
bomb splinters.
Contused tissues , muscles are also lacerated
and devitalized.
May be associated with Injury to underlying
vessels, nerves or bone.
Contaminated with dust, sand, mud, bone
splinters,…
Lacerations and avulsive wounds best
sutured in first 6hrs. Not latter than 24 hrs
Suturing layer by layer(Skin,muscle,fascia.
And mucosa)
Debridement and irrigation
Open dressing with tetracycline 1%
Prophylactic antibiotics( broad spectrum
antibiotics: Amoxicillin,
Augmentin,Ceftriaxone, not cloxacillin!!! Add
metronidazole if tissues are infected :
Clindamycin of allergic to penicillins and
Cepharosporins)
Oral mouthwashes(Rhexedine,
Chlorhexidine,hydrogen peroxide,…)
Intra-oral wounds never be clean!!!
Soft tissues injuries and their management
• Penetrating and punctured
wound
Caused by pin pointed objects
like knife , bullet, bomb splinters.
Careful clinical examination
Other investigations like CT scan
are required.
• Gun shot injuries
They are penetrating injuries
but classified separately due to
their complicated management.
They are penetrating ,
perforating and avulsive.
Hard tissue trauma and their management
• Midface Fractures
• Lefort I
 Detached maxillary alveolar process
 Management:MMF,ORIF
• Lefort II(Pyramidal)
 Detached Maxilla(mobile maxilla)
 Management:MMF,ORIF
• Lefort III(transverse, cranio-facial disjunction)
 The face is detached from the cranial cavity
Airway compromises
Assending meningitis
Cavernous thrombosis
Management:ORIF
Hard tissue trauma and their management
• Features: facial echymoses, facial
tenderness,conjunctiva echymoses, disturbed
occular movements, Step deformities, CSF
Rhinorrhea and Otorhea, Malocclusion, anterior
open bites.palatal echymoses
• Usually associated with Head injury( traumatic
brain injury),C-spine injury or Chest And
extremities fractures .
• Downward and posterior displacement of
detached segment.
• Emergency Airway compromises , highly bleed!!!
• ATLS
• Antibiotics+Painkillers+ mouthwash
• Investigation: FBC,renal function,liver anzymes, CT-
scan of head and neck without contrast.
Hard tissue trauma and their management
• Mandibular fractures
 Features: swelling on site, trissmuss, sublingual hematoma,
Malocclusion (open bites),step deformity upon palpation.
 Investigation:OPG,PA of Skull,Lateral skull
 Classification: symphysial,parasymhysial,angle, and ramus
and condyle of the mandible.
 Bilateral parasymphysial or body of mandible fractures have
downward and posterior displacement due to suprahyoid
muscles that cause Airway compromise
 Open or closed, displaced or non displaced.
 Treatment: Airway patency!!!!
 IM Dexamethasone
 Antibiotics+ pain killers and mouthwash
 Advise patients to lye in rescue position.
 Management is close with(MMF) or is for ORIF
Hard tissue trauma and their management
• Dental trauma and management
• Avulsion: do not throw avulsed tooth!! Keep it in
NS,Milk wait for a dentist to do re-implantation.
Emergency treatment:Pain management,
prophylaxis antibiotics+ mouthwash. Re-
implantation and fixation.
• Subluxation: Teeth are mobile, not in their
anatomical position, Emergency treatment:Pain
management,Oral hygiene And prophylaxis+ soft
diet then dentist will split the teeth
• Crown fractures: Oral hygiene,cover with Calcium
hydroxide.
• Dento-alveolar fractures: segment of teeth in same
region displaced from their location, mobile,
painful.Emergency treatment: pain management,
Prophylactic antibiotics + mouthwash. MMF,
interdental wiring of composite splitting.
Complications of oral and maxillofacial trauma
• Immediate and early: Airway obstruction, Bleeding, nerve injuries,
Pain, swelling, malocclusion, Shock, death.
• Intermediate: Trismus , Infections, Sepsis , Infective endocarditis,
meningitis ,Cavernous thrombosis, Fascial space infections, death.
• Late: Osteomyelitis, facial deformity, Malunion,malocclusions, scars,
PTSD(post-traumatic stress disorder , TMJ ankylosis.
PROPHYLACTIC ANTIBIOTHERRAPY
• MODE OF ACTION
• Cell wall active agents
• Protein synthesis inhibitors
• DNA synthesis inhibitors
PENICILLINS
Narrow spectrum
• Natural penicillins
• Pen G and Pen V are effective on Gram + cocci and Bacilli,
few gram- cocci and spirochetes like Treponema pallidum
but Fail on gram – Bacilli
• Used in prophylactis of rheumatic fever in children with
pharyngitis
• Mixed aerobic and anaerobic infection
• Very very narrow spectrum
• Called also Antistaphylococcal penicillins
• Methicillin:interstitial nephritis
• Nafcillin:nephrititis,neutropenia
• Cloxacillin
• Dicloxacillin
• They are active only on staphylococcus
Wide spectrum
• Ampicillin
• Amoxicillin
• Active on both Gram +and gram – bacteria
• Enterococci.
• Hemophillus influenza
• E coli
• Listeria monocytogenus
• Proteus
• Salmonera
• Clavulanic acid
• Sulbactam
• Tazobactam
PENICILLINS
Extended spectrum
• Augmentin(amoxicillin+clavulani
c acid)
• Unasyn(ampicillin+Sulbactam)
Extended broad spectrum
• Antipseudomona penicillins
• Piperacillin
• Carbenicillin
• Ticarcillin
• Zosyn is Piperacillin+ Tazobactam
• Timentin is Ticarcillin+clavulaic
acid
Most Prophylactic combinations used in OMFS
• Amoxicillin 30-50mg/kg TID
• Cloxacillin 30-50mg/kg TID
• Metronidazole 15mg/kg TID
• Ceftriaxone 30mg/kg BID
• Gentamycin 4-7mg/kg OD maximum 160mg
• Augmentin 625mg
• Combination of amoxicillin + metronidazole
• Combination of ceftriaxone + metronidazole
• Combination of ceftriaxone + metronidazole + gentamycin
• Mouth washes
• Rexedine, betadine, chlorhexidine
• Hydrogen peroxide, listerine,..
• Ointments
• Tetracycline 3%
ANTIBIOTICS
• PENICILLINS
• CLINDAMYCINE
• VANCOMYCIN
• METRONIDAZOLE
• MACROLIDES
• TETRACYCLINES
• CEPHALOSPORINS
• ANTIFUNGAL
Thank you
References
• American College Of Surgeons, Committee On Trauma.(2018) ATLS
Manual. The 10th Ed.
• james.R. (2014)'Contemporary oral and maxillofacial surgery 7th
edition’.
• David et al.(2003)Textbook of general and oral surgery. edn.
Philadelphia,PA: Chulchil Livingstone/Elsevier.
• Mohammad et al. (2013). ‘Maxillofacial reconstruction of ballistic
injuries’. A textbook of advanced oral and maxillofacial surgery. P
532-557.

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Emergency management of oral and maxillofacial trauma including_100844.pptx

  • 1. Emergency management of oral and maxillofacial trauma including prophylactic antibiotherapy. Dr. NDAYISHIMIYE Samuel Dental Surgeon.
  • 2. OUTLINES • Introduction • Etiology of oral and maxillofacial trauma • Assessment of patient with OMF trauma • Soft tissues trauma • Mandible fracture and emergency management • Midface fractures and emergency management • Dental trauma • Complications of oral and maxillofacial trauma • Prophylactic ntibiotherrapy • References
  • 3. Introduction • What is tissue trauma? • Is the damage of tissues by physical , thermal, chemicals agents. • When do we say maxillofacial trauma is an emergency? • Airway compromise • Brain injury • C-spine injury • Avulsion of tissues.
  • 4. Introduction contd.. • Oral and maxillofacial region is crucial area that serves in Airway , esthetic, mastication and speech. • Facial injuries deserve special attention because of their complications and esthetic significance. • Facial trauma are life threatening because of airway compromise, bleeding, and infections. • injury causes include moto-vehicle accidents ,falls, sports, fights, and domestic violence. • Facial trauma is among the common causes of maxillofacial emergencies • May be associated with other life threatening injury like C-spine, brain injury and extremities..
  • 5. Etiology of OMF trauma • Most of cause of the injuries include moto-vehicle , accidents ,falls, sports, fights, and domestic violence. • Motorcycle(24.7%) • Moto-car(20.9%) • Fall accident(17.6%) • Bicycle(14.3%) • Assault(7.7%) • Domestic violence(7.1%) • Sports accident(5.5%) • Others(2.2%)
  • 6. Classification of oral and maxillofacial injuries Soft tissues trauma Abrasions Contusions Echymosis Lacerations avulsion Hard tissues trauma fractures Upper face fractures Mid-face fractures Lower face fractures Displacement dislocations Teeth and dento-alveolar injuries.
  • 7. Emergency management of OMF Trauma • emergency management of oral and maxillofacial trauma patient requires advanced trauma life support(ATLS) • Triage • Primary survey • Resuscitation • Adjunct to primary survey • ABCDE • Secondary survey • Adjunct to secondary survey • Definitive care
  • 8. Emergency management contd,…… • Secondary survey(AMPLE) Head to toe examination Allergy Medications Past illness/pregnancy Last meal Exposure/event. • Triage: who is more critical? based on ABC priorities. Primary survey: Airway and C spine protection. Breathing and Ventilation Circulation with hemorrhage control Disability (neurological status GCS, sensation, movement and motor power) Exposure/environmental control.
  • 9. Emergency management contd,…… • Airway • Call the patient if not responding consider the Airway to be compromised. • Inspect for foreign body, facial, mandibular, laryngeal or tracheal fracture. • Suction of all clots, and secretions. • Jaw-thrust or chin-lift maneuver to open airways. • Oro-tracheal intubation for unconscious without gag reflex. • Prevent excessive movement of C spine • Might have C spine injury. • C collar placement. • Breathing and ventilation • Ensure chest expansion • Pulse oximeter to see hemoglobin saturation. • Look for signs of tension pneumothorax, massive hemothorax,open pneumothorax, tracheal or laryngeal injuries. • Supplemental oxygen • tension pneumothorax affect both respiration and circulation • Needle decompression
  • 10. Emergency management contd,…… • Areas of tension pneumothorax needle decompression, jaw thrust and chin lift for airway and breathing management
  • 11. Emergency management contd,…… • Circulation • Assess cardiac output and bleeding. • Quick identification and control of hemorrhage is crucial. • If tension pneumothorax is excluded, hypotension is the cause of chock until proven otherwise. • 3 elements of CO assessment • Level of consciousness: stable/altered • Skin perfusion : pink face, extremities/gray facial skin/pale and cold extremities. • Pulse: rapid thread, absent central pulse point for immediate need of resuscitation. • External bleeding has to be controlled by direct pressure on wound. Tourniquet may be applied if direct pressure on extremity is not effective. • Major areas of internal bleeding are chest, abdomen , retroperitoneum, pelvis and long bones. • Use of imaging helps. Chest x-ray, pelvic x-ray, FAST(focused assessment with sonography for trauma) • Replacement of intravascular volume.
  • 12. Emergency management contd,…… • Disability • GCS • Pupillary size and reaction • Determine spinal cord injury level • Decreased consciousness may indicate Brain hypoxia,  hypo-perfusion ,  hypoglycemia, direct cerebral injury • Adequate oxygenation and perfusion to prevent secondary brain injury
  • 13. Emergency management contd,…… • Exposure and environmental control removal of garments for thorough examination Cover with blanket to prevent hypothermia Warm IV fluids to the body temperature.
  • 14. Emergency management contd,…… • Secondary survey(AMPLE) Head to toe examination Allergy Medications Past illness/pregnancy Last meal Exposure/event.
  • 15. Assessment of patient with OMF trauma • History of mechanism of injury is the key(from the patient or whiteness who were at the scene if patient is unconscious) • Examination should be quick and proper. • Begin with overall inspection noting any facial asymmetries,wound,hemorrhage,serous discharge and ecchymosis. • Neurological examination of 12 CN. • Assessment of sensory nerves(ophthalmic , maxillary and mandibular.)
  • 16. Assessment cont’d,.. • Soft tissues injuries • Lips(through band through lacerations) • Facial symmetry • Occlusion : disturbed in maxillofacial fractures. • Peri-orbital and conjuctival ecchymosis, • Palatal and sublingual hematoma • CSF leakage(rhinorrhea, otorrhea) • Tenderness in facial area • Step deformity • Respiration pattern • C spine dermatomes.
  • 17. Soft tissues injuries and their management • Hematoma:  is localized collection of the blood in subcutaneous, intramuscularly or submucosal.  Most are reabsorbed  Persistent ones may require incision and drainage.  Antibiotic cover for prevention of hematoma infection. • Abrasions:  friction between an object and soft tissue surface.  Epidermis involved but sometimes deeper layers’  Painful.  Mngt: clean and irrigate with saline  Foreign body removal.  Topical antibiotics • Contusion:  due to blow or fall against hard and brunt object.  Blood extravasation from subcutaneous or submucosa causing bruises.  Look for the osseous trauma!!!  Mgt: ice pack.
  • 18. Soft tissues injuries and their management • Lacerated and avulsive wound Most frequently accoutered type of wound. Vehicle accidents, Low velocity missiles or bomb splinters. Contused tissues , muscles are also lacerated and devitalized. May be associated with Injury to underlying vessels, nerves or bone. Contaminated with dust, sand, mud, bone splinters,… Lacerations and avulsive wounds best sutured in first 6hrs. Not latter than 24 hrs Suturing layer by layer(Skin,muscle,fascia. And mucosa) Debridement and irrigation Open dressing with tetracycline 1% Prophylactic antibiotics( broad spectrum antibiotics: Amoxicillin, Augmentin,Ceftriaxone, not cloxacillin!!! Add metronidazole if tissues are infected : Clindamycin of allergic to penicillins and Cepharosporins) Oral mouthwashes(Rhexedine, Chlorhexidine,hydrogen peroxide,…) Intra-oral wounds never be clean!!!
  • 19. Soft tissues injuries and their management • Penetrating and punctured wound Caused by pin pointed objects like knife , bullet, bomb splinters. Careful clinical examination Other investigations like CT scan are required. • Gun shot injuries They are penetrating injuries but classified separately due to their complicated management. They are penetrating , perforating and avulsive.
  • 20. Hard tissue trauma and their management • Midface Fractures • Lefort I  Detached maxillary alveolar process  Management:MMF,ORIF • Lefort II(Pyramidal)  Detached Maxilla(mobile maxilla)  Management:MMF,ORIF • Lefort III(transverse, cranio-facial disjunction)  The face is detached from the cranial cavity Airway compromises Assending meningitis Cavernous thrombosis Management:ORIF
  • 21. Hard tissue trauma and their management • Features: facial echymoses, facial tenderness,conjunctiva echymoses, disturbed occular movements, Step deformities, CSF Rhinorrhea and Otorhea, Malocclusion, anterior open bites.palatal echymoses • Usually associated with Head injury( traumatic brain injury),C-spine injury or Chest And extremities fractures . • Downward and posterior displacement of detached segment. • Emergency Airway compromises , highly bleed!!! • ATLS • Antibiotics+Painkillers+ mouthwash • Investigation: FBC,renal function,liver anzymes, CT- scan of head and neck without contrast.
  • 22. Hard tissue trauma and their management • Mandibular fractures  Features: swelling on site, trissmuss, sublingual hematoma, Malocclusion (open bites),step deformity upon palpation.  Investigation:OPG,PA of Skull,Lateral skull  Classification: symphysial,parasymhysial,angle, and ramus and condyle of the mandible.  Bilateral parasymphysial or body of mandible fractures have downward and posterior displacement due to suprahyoid muscles that cause Airway compromise  Open or closed, displaced or non displaced.  Treatment: Airway patency!!!!  IM Dexamethasone  Antibiotics+ pain killers and mouthwash  Advise patients to lye in rescue position.  Management is close with(MMF) or is for ORIF
  • 23. Hard tissue trauma and their management • Dental trauma and management • Avulsion: do not throw avulsed tooth!! Keep it in NS,Milk wait for a dentist to do re-implantation. Emergency treatment:Pain management, prophylaxis antibiotics+ mouthwash. Re- implantation and fixation. • Subluxation: Teeth are mobile, not in their anatomical position, Emergency treatment:Pain management,Oral hygiene And prophylaxis+ soft diet then dentist will split the teeth • Crown fractures: Oral hygiene,cover with Calcium hydroxide. • Dento-alveolar fractures: segment of teeth in same region displaced from their location, mobile, painful.Emergency treatment: pain management, Prophylactic antibiotics + mouthwash. MMF, interdental wiring of composite splitting.
  • 24. Complications of oral and maxillofacial trauma • Immediate and early: Airway obstruction, Bleeding, nerve injuries, Pain, swelling, malocclusion, Shock, death. • Intermediate: Trismus , Infections, Sepsis , Infective endocarditis, meningitis ,Cavernous thrombosis, Fascial space infections, death. • Late: Osteomyelitis, facial deformity, Malunion,malocclusions, scars, PTSD(post-traumatic stress disorder , TMJ ankylosis.
  • 25. PROPHYLACTIC ANTIBIOTHERRAPY • MODE OF ACTION • Cell wall active agents • Protein synthesis inhibitors • DNA synthesis inhibitors
  • 26. PENICILLINS Narrow spectrum • Natural penicillins • Pen G and Pen V are effective on Gram + cocci and Bacilli, few gram- cocci and spirochetes like Treponema pallidum but Fail on gram – Bacilli • Used in prophylactis of rheumatic fever in children with pharyngitis • Mixed aerobic and anaerobic infection • Very very narrow spectrum • Called also Antistaphylococcal penicillins • Methicillin:interstitial nephritis • Nafcillin:nephrititis,neutropenia • Cloxacillin • Dicloxacillin • They are active only on staphylococcus Wide spectrum • Ampicillin • Amoxicillin • Active on both Gram +and gram – bacteria • Enterococci. • Hemophillus influenza • E coli • Listeria monocytogenus • Proteus • Salmonera • Clavulanic acid • Sulbactam • Tazobactam
  • 27. PENICILLINS Extended spectrum • Augmentin(amoxicillin+clavulani c acid) • Unasyn(ampicillin+Sulbactam) Extended broad spectrum • Antipseudomona penicillins • Piperacillin • Carbenicillin • Ticarcillin • Zosyn is Piperacillin+ Tazobactam • Timentin is Ticarcillin+clavulaic acid
  • 28. Most Prophylactic combinations used in OMFS • Amoxicillin 30-50mg/kg TID • Cloxacillin 30-50mg/kg TID • Metronidazole 15mg/kg TID • Ceftriaxone 30mg/kg BID • Gentamycin 4-7mg/kg OD maximum 160mg • Augmentin 625mg • Combination of amoxicillin + metronidazole • Combination of ceftriaxone + metronidazole • Combination of ceftriaxone + metronidazole + gentamycin • Mouth washes • Rexedine, betadine, chlorhexidine • Hydrogen peroxide, listerine,.. • Ointments • Tetracycline 3%
  • 29. ANTIBIOTICS • PENICILLINS • CLINDAMYCINE • VANCOMYCIN • METRONIDAZOLE • MACROLIDES • TETRACYCLINES • CEPHALOSPORINS • ANTIFUNGAL
  • 31. References • American College Of Surgeons, Committee On Trauma.(2018) ATLS Manual. The 10th Ed. • james.R. (2014)'Contemporary oral and maxillofacial surgery 7th edition’. • David et al.(2003)Textbook of general and oral surgery. edn. Philadelphia,PA: Chulchil Livingstone/Elsevier. • Mohammad et al. (2013). ‘Maxillofacial reconstruction of ballistic injuries’. A textbook of advanced oral and maxillofacial surgery. P 532-557.