This document summarizes the services offered by nanoimmunotech, a European nanobiotechnology company. It offers exclusive characterization services for nanomaterials to optimize their performance for biotechnological applications. It has qualified staff, state-of-the-art labs, and standardized testing protocols. Nanoimmunotech also provides consultancy and validation for nanosystem design and production as well as biosensor design using its proprietary technologies.

1. nanoimmunotech also offers exclusive services
of biological and physicochemical characteri-
zation of nanostructures and products contai-
ning them, for optimizing their performance
as a first step to their previous use in biotech-
nological applications.
The company has highly qualified and inter-
nationally recognized human resources, state-
of-the-art laboratory capabilities, standardi-
zed protocols. Finally, nanoimmunotech has the
know-how to proper advice and validate the
design and production of various nanosystems
as well as the design of biosensors thanks to
its proprietary technologies.
BUSINESS
AREAS
nanoimmunotech is a new European company in the nanobio-
technology sector, founded in August 2009.
nanoimmunotech core business consists in the bioconju-
gation of micro/nanoparticles and biomolecules aiming
to massively simplify the production of conjugates that
are needed for research and for biotechnological appli-
cations in different sectors (biomedical, pharmaceutics,
cosmetics, veterinary, agro-food, environmental, etc…).
www.nanoimmunotech.eu
the simplest, quickest and most versatile bioconjugation
technology (mono-and multifunctionalization solution)
NITZIPPER is a family of products ready to be used in an easy, immediate and effective conjugation
through a new and revolutionary bioconjugation technology that allows you to combine many diffe-
rent types of micro/ nanostructures, biomolecules (antibodies, dyes, enzymes, linkers, drugs and other
molecules), in practically any combination in an oriented way and without modifying their properties.
NITZIPPER is also a multi-functionalization tool that allows you to join not just two different types of
molecules or micro/nanostructures with each other, but many of them simultaneously, allowing you
to create a multitude of new micro/nanosystems for their use in infinite applications. It is not a specific
solution for a specific application. It is a technology that you can use for improving traditional applica-
tions (antibody labeling, immunoassays, flow cytometry, ELISA, biosensing, magnetic separation, and
many others) but also for exploring the ones you can possibly imagine or need.
A strong and stable union between the different pieces of the micro/nanosystems is performed
thanks to matching linkers named Linker U and Linker T, each one on the surface of NITZIPPER pieces.
More information on www.nitzipper.com
NITBIOSAFE biological (in vitro in vivo) characterization services of nanosystems
NITBIOSAFE is the quality brand offered worldwide by nanoimmunotech, gathering all the necessary ser-
vices for consultancy and biological (in vitro in vivo) characterization of nanostructured materials.
NITBIOSAFE offers you a wide range of characterization techniques that will allow you to easily and
quickly access the true biological properties of your nanostructures:
biocompatibility studies Aggregation tests, sterilization, nanotoxicity, lethal dosis determination,
biodistribution.
immunologic studies Dendritic cells differentiation, coagulation induction by leucocytes, leuco-
cytes proliferation study, nitric oxyde production, chemotaxis assay, phago-
cytosis assay, etc.
hematologic studies Interaction of plasmatic proteins, complement activation, coagulation study.
efficiency studies NITBIOSAFE assays are based on standardized protocols and experimental en-
vironments that ensure optimal laboratory results, implementing USA re-
commendations and all EU regulation regarding nanosafety.
More information on www.nitbiosafe.com
NITCHARACTER physicochemical characterization services of micro/nanosystems
NITCHARACTER is the quality brand offered worldwide by nanoimmunotech, gathering a complete portfolio
of physicochemical characterization services of micro/nanomaterials.
NITCHARACTER provides consultancy and high precision testing using techniques that will allow you
to easily and quickly access the true character of your micro/nanostructures, such as the following
techniques:
– Size and size distribution (DLS, SEM, TEM) - Morphological analysis (TEM, SEM)
– Surface net charge determination (Zeta Potential).
– Chemical and structural composition (EDX, Elemental analysis, ICP-MS, FTIR, XPS,
RMN-1H, TGA).
– Instrinsic properties (SQUID, UV-vis spectroscopy, Fluorescence spectroscopy).
More information on www.nitcharacter.com
NITZIPPER
®

2. BUSINESS
AREAS
CONTACT US
info@nanoimmunotech.es
+34 976 369 300
the marketplace for your complete particle needs
NITPARTICLES aims to offer to its customers the opportunity to find, in a centralized manner, a large
variety of high quality particles (micro- and nanoparticles), some developed by worldwide highly
prestigious companies and others developed in nanoimmunotech’s own laboratories, covering almost
all comprehensive needs.
Accordingly, NITPARTICLES offers a particles distribution service of reliable companies specialized in
the development and production of all types of particles such as magnetic, metal, polymer particles,
among others.
More information on www.nanoimmunotech.eu/en/business-areas/nitparticles
NITBIOSENSING High-precision analytical tools for your bio-applications
Thanks to the built-up knowledge of nanoimmunotech in bioconjugation and aiming to respond to the
increasing demand of analytical tools in a variety of biotechnological applications, nanoimmunotech
has developed a new quality brand, NITBIOSENSING, offering its proprietary revolutionary biosensor
technologies.
NITBIOSENSING currently offers two leading biosensor technologies, a colorimetric biosensor and a ther-
mal biosensor, with highly attractive characteristics, including their specificity, high sensitivity, and
response capacity leading to a short analysis time, versatility and low cost.
colorimetric biosensor The biosensor is based on the detection of an analyte by a colorimetric
method with the use of gold nanoparticles, obtaining a high sensitivity in
detecting the analyte concentration.
thermal biosensor The biosensor technology is based on the visual detection of an analyte by
the color change in the support areas where the analyte is present, produ-
ced as a result of the heat generated by the metal nanoparticles when they
are irradiated with an external light source.
NITPARTICLES