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Look Alike And Sound
Alike Medications
PH. Wael Alsorihi
Look Alike And Sound Alike
3/19/2018 1
DEFINITION OF LASA
FACTORS OF ERROR WITH LASA
CATEGORIES IN LASA
FDA AND ISMP LISTS OF LASA
Strategies to avoid errors with LASA
3/19/2018 2
involve medications that are visually similar in physical appearance or
packaging and names of medications that have spelling similarities and/or
similar phonetics
These confusing drug names are one of the main causes of medication error,
There are many sound and look alike drugs that would result in medication error.
These errors may cause harm or even death to patients.
DEFINITION
Look Alike Sound Alike (LASA)
3/19/2018 3
The main reasons for improper dispensing of confusing drug names ,
may due to lack of knowledge of registered pharmacist or due to less number of
pharmacist during rush hours.
Individual factors take into capabilities, limitations, and
characteristics, such as, illegible handwriting, knowledge deficit, etc.
Environmental factors work environment or within the workflow
process, such as drug storage, environmental distractions, drug
shortage, etc.
INDIVIDUAL FACTORS
ENVIRONMENTALFACTORS
UNIQUE FACTORS
Unique factors are special characteristics to look-alike/sound-alike
drug themselves, such as similar dose, similar indication, same
ingredients available in multiple formulations, etc.
https://www.ismp-canada.org/download/PharmacyConnection/PC2014-02
4
LASA drugs-Similar brand names, different generic drugs
Losec® (OMEPRAZOLE) &Lasix® (furosemide)
LASA drugs- Similar brand names , same generic drug
CETRALON ® and CETRO ®, (CETIRIZINE HYDROCHLORIDE )
LASA drugs- Similar brand names with additional letter
Fevadol , Fevadol Plus, FEVADOL EXTRA FEVADOL COLD & FLU
LASA drugs- Similar brand names of the Antibiotics group
CIFLOX ® (CIPROFLOXACIN) , MOXIFLOX ® (MOXIFLOXACIN)
that can easily cause confusion while prescribing, dispensing and
administration ,
LASA drugs- Same drug, different Dosage forms
VOLTAREN® Tablet ,SUPP , Gel , eye Drops , ampules ……
LASA drugs- Same drug, different release characteristics
( NIFEDIPINE ) ADALAT RETARD ® , ADALAT LA
LASA drugs- Same brand or Generic name, different composition
Amphotericin B (Abelcet®)
Liposomal Amphotericin B (AmBisome®)
LASA drugs- Generic Drug pairs
VINCRISTINE
EPHEDRINE
LORAZEPAM
VINBLASTINE
EPINEPHRINE
CLONAZEPAM
FDA
3/19/2018 7
The US Food and Drug Administration
(FDA) list of drug names with
recommended tall man letters was
initiated in 2001 with the agency’s Name
Differentiation Project
ISMP institute for Safe MedicationPractices
Since 2008, ISMP has maintained a list of drug
name pairs and trios with recommended, bolded
tall man (uppercase) letters to help draw attention
to the dissimilarities in look-alike drug names.
The list includes mostly generic-generic drug name
pairs, although a few brand-brand or brand-generic
name pairs are included.
The ISMP list is not an official
list approved by FDA.
It is intended for voluntary
use by healthcare
practitioners and drug
information and technology
vendors.
ISMP
Lorem ipsum dolor sit
amet, consectetur
adipiscing elit, sed do
eiusmod tempor
incididunt ut labore et
dolore magna aliqua.
3/19/2018 8
Any manufacturers’ product
label changes require FDA
approval.
3/19/2018 9
ISMP Confused
Drug name List
3/19/2018 10
Strategies to avoid errors
with LASA
Monitoring
Information
Patient Education
Procurement
Storage
Dispensing
Prescribing
Administration
Procurement
Minimise the availability of multiple medicines
strengths , avoid similar packaging and appearance
compare them with existing packaging.
Dispensing/Supply
Storage
Use Tall Man lettering to emphasise differences in medications with
sound-alike
Use additional warning labels for look-alike medicines. Warning labels
should be uniform throughout the respective facility to facilitate
identification.
Prescribing
Lorem ipsum dolor sit amet,
consectetur adipiscing elit,
sed do eiusmod tempor
incididunt ut labore et
dolore magna aliqua.
Administration
Monitoring
Information
Patient
Education
Strategies to avoid errors
with LASA Your Subtitle
3/19/2018 12
Minimise the availability
of multiple medicines
strengths , avoid similar
packaging and
appearance compare
them with existing
packaging.
Procurement
3/19/2018 13
 Use Tall Man lettering to emphasise
 labels for look-alike medication.
 locations separate from each other
Storage
3/19/2018 14
 using both the brand , generic names ,
dosage form, dose and indication for use.
 computerized prescriber order entry (CPOE) should
used Tall Man lettering.
 Minimize the use of Verbal and Telephone orders.
Prescribing
3/19/2018 15
 Identify medicines based on its name and strength and not by its
appearance or location.
 Double checking should be conducted during the dispensing and
supply process.
 Highlight changes in medication appearances to patients upon dispensing
Dispensing
3/19/2018 16
(a)Read carefully the label each time a medication is
prior to administration.
(b)Check the purpose of the medication and the dose
prior to administration
Administration
3/19/2018 17
 Monitor new drugs added to the hospital formulary as they are
released and provide guidelines to These new drugs.
Monitor patients who may have received wrong medications
as result of LASA medication error..
Monitoring
3/19/2018 18
 Update healthcare professionals of changes on the list of LASA and
confusing drug names.
 Provide education on LASA medications to healthcare professionals
at orientation and as part of continuing education
Information
3/19/2018 19
 Inform patients on changes in medication appearances.
 Encourage patients to learn the names of their medications.
Patient Education
3/19/2018 20
Example of the Strategies to avoid errors
with LASA in kfhm
3/19/2018 21
3/19/2018 22
3/19/2018 23
3/19/2018 24
3/19/2018 25
DAPSONE 100 MG
SODIUM BICARBONATE
375MG
FLUDROCORTISONE 0.1MG
3/19/2018 26
3/19/2018 27
2 mg
3/19/2018 28
Ampoule
3/19/2018 29
3/19/2018 30
3/19/2018 31
3/19/2018 32
3/19/2018 33
3/19/2018 34
Reminders, Checklists, Double Checks” and “Rules &
Policies” are used to remind or control people
not necessarily to fix systems.
“Education & Information” is an important strategy
when it is combined with other that strengthen the
system.
Take Home Message
3/19/2018 35
Strategies to Prevent Medication Errors from Look-Alike and Sound-Alike Drug Names

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Strategies to Prevent Medication Errors from Look-Alike and Sound-Alike Drug Names

  • 1. Look Alike And Sound Alike Medications PH. Wael Alsorihi Look Alike And Sound Alike 3/19/2018 1
  • 2. DEFINITION OF LASA FACTORS OF ERROR WITH LASA CATEGORIES IN LASA FDA AND ISMP LISTS OF LASA Strategies to avoid errors with LASA 3/19/2018 2
  • 3. involve medications that are visually similar in physical appearance or packaging and names of medications that have spelling similarities and/or similar phonetics These confusing drug names are one of the main causes of medication error, There are many sound and look alike drugs that would result in medication error. These errors may cause harm or even death to patients. DEFINITION Look Alike Sound Alike (LASA) 3/19/2018 3
  • 4. The main reasons for improper dispensing of confusing drug names , may due to lack of knowledge of registered pharmacist or due to less number of pharmacist during rush hours. Individual factors take into capabilities, limitations, and characteristics, such as, illegible handwriting, knowledge deficit, etc. Environmental factors work environment or within the workflow process, such as drug storage, environmental distractions, drug shortage, etc. INDIVIDUAL FACTORS ENVIRONMENTALFACTORS UNIQUE FACTORS Unique factors are special characteristics to look-alike/sound-alike drug themselves, such as similar dose, similar indication, same ingredients available in multiple formulations, etc. https://www.ismp-canada.org/download/PharmacyConnection/PC2014-02 4
  • 5. LASA drugs-Similar brand names, different generic drugs Losec® (OMEPRAZOLE) &Lasix® (furosemide) LASA drugs- Similar brand names , same generic drug CETRALON ® and CETRO ®, (CETIRIZINE HYDROCHLORIDE ) LASA drugs- Similar brand names with additional letter Fevadol , Fevadol Plus, FEVADOL EXTRA FEVADOL COLD & FLU LASA drugs- Similar brand names of the Antibiotics group CIFLOX ® (CIPROFLOXACIN) , MOXIFLOX ® (MOXIFLOXACIN) that can easily cause confusion while prescribing, dispensing and administration ,
  • 6. LASA drugs- Same drug, different Dosage forms VOLTAREN® Tablet ,SUPP , Gel , eye Drops , ampules …… LASA drugs- Same drug, different release characteristics ( NIFEDIPINE ) ADALAT RETARD ® , ADALAT LA LASA drugs- Same brand or Generic name, different composition Amphotericin B (Abelcet®) Liposomal Amphotericin B (AmBisome®) LASA drugs- Generic Drug pairs VINCRISTINE EPHEDRINE LORAZEPAM VINBLASTINE EPINEPHRINE CLONAZEPAM
  • 7. FDA 3/19/2018 7 The US Food and Drug Administration (FDA) list of drug names with recommended tall man letters was initiated in 2001 with the agency’s Name Differentiation Project ISMP institute for Safe MedicationPractices Since 2008, ISMP has maintained a list of drug name pairs and trios with recommended, bolded tall man (uppercase) letters to help draw attention to the dissimilarities in look-alike drug names. The list includes mostly generic-generic drug name pairs, although a few brand-brand or brand-generic name pairs are included.
  • 8. The ISMP list is not an official list approved by FDA. It is intended for voluntary use by healthcare practitioners and drug information and technology vendors. ISMP Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. 3/19/2018 8
  • 9. Any manufacturers’ product label changes require FDA approval. 3/19/2018 9
  • 10. ISMP Confused Drug name List 3/19/2018 10
  • 11. Strategies to avoid errors with LASA Monitoring Information Patient Education Procurement Storage Dispensing Prescribing Administration
  • 12. Procurement Minimise the availability of multiple medicines strengths , avoid similar packaging and appearance compare them with existing packaging. Dispensing/Supply Storage Use Tall Man lettering to emphasise differences in medications with sound-alike Use additional warning labels for look-alike medicines. Warning labels should be uniform throughout the respective facility to facilitate identification. Prescribing Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Administration Monitoring Information Patient Education Strategies to avoid errors with LASA Your Subtitle 3/19/2018 12
  • 13. Minimise the availability of multiple medicines strengths , avoid similar packaging and appearance compare them with existing packaging. Procurement 3/19/2018 13
  • 14.  Use Tall Man lettering to emphasise  labels for look-alike medication.  locations separate from each other Storage 3/19/2018 14
  • 15.  using both the brand , generic names , dosage form, dose and indication for use.  computerized prescriber order entry (CPOE) should used Tall Man lettering.  Minimize the use of Verbal and Telephone orders. Prescribing 3/19/2018 15
  • 16.  Identify medicines based on its name and strength and not by its appearance or location.  Double checking should be conducted during the dispensing and supply process.  Highlight changes in medication appearances to patients upon dispensing Dispensing 3/19/2018 16
  • 17. (a)Read carefully the label each time a medication is prior to administration. (b)Check the purpose of the medication and the dose prior to administration Administration 3/19/2018 17
  • 18.  Monitor new drugs added to the hospital formulary as they are released and provide guidelines to These new drugs. Monitor patients who may have received wrong medications as result of LASA medication error.. Monitoring 3/19/2018 18
  • 19.  Update healthcare professionals of changes on the list of LASA and confusing drug names.  Provide education on LASA medications to healthcare professionals at orientation and as part of continuing education Information 3/19/2018 19
  • 20.  Inform patients on changes in medication appearances.  Encourage patients to learn the names of their medications. Patient Education 3/19/2018 20
  • 21. Example of the Strategies to avoid errors with LASA in kfhm 3/19/2018 21
  • 26. DAPSONE 100 MG SODIUM BICARBONATE 375MG FLUDROCORTISONE 0.1MG 3/19/2018 26
  • 35. Reminders, Checklists, Double Checks” and “Rules & Policies” are used to remind or control people not necessarily to fix systems. “Education & Information” is an important strategy when it is combined with other that strengthen the system. Take Home Message 3/19/2018 35