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Natural Product Radiance Vol 4(1) January-February 200518
Article
Essential oils as Therapeutics
S C Garg
Department of Chemistry
Dr. Harisingh Gour University, Sagar 470 003, Madhya Pradesh, India
E-mail: profscgarg@hotmail.com
Abstract
Essential oils are the volatile secondary plant metabolites which mainly
consist of terpenoids and benzenoids. Research in the later half of 20th century
has revealed that many curative properties attributed to various plants in
indigenous medicine are also present in their essential oils. These oils exert a
number of general effects from the pharmacological viewpoint. When applied
locally, the essential oils mix readily with skin oils, allowing these to attack the
infective agents quickly and actively. Therapeutic properties of various essential
oils based on folklore, experiences and claims of aromatherapists and scientific
studies have been summarised in this review. In vitro studies conducted by the
author on antimicrobial and anthelmintic properties of some essential oils have
also been discussed.
Keywords: Essential oils, Therapeutics, Aromatherapy, Antimicrobial,
Anthelmintic.
IPC Code; Int. cl.7
āŽÆ C11B 9/00, A61P/00, A61P 31/00, A61P 33/10
Introduction
Herbal medicines are the gift of
ā€˜Mother Natureā€™ to its children, the
mankind. The fragrance of myriad flowers
and herbs enchants man, elevates the
mood and leads to feeling good. Essential
oils, the secondary plant metabolites, and
the most sublime extractive of plants,
found their way from herbal medicine.
Inhaling the aromas for therapeutic
purposes and then use of essential oils in
whatever way they are useful in therapy
became the basis of aromatherapy. The
recorded history of ancient civilizations
indicate the use of aromatic plants like
lavender, cedar and cypress for curing
ailments, offerings to deities and
anointments. In 1928, a French chemist
Dr. Rene Gattefosse, while working on
essential oils badly burned his hand in
laboratory and desperately plunged it into
the nearest vat containing lavender oil. He
wasastonishedtoseehowquicklythepain
ceased having no blisters and the skin
healed quickly than normal without
forming a scar. Later on he studied the
therapeutic benefits of essential oils and
coined the word ā€œAromatherapieā€ (the
anglicized form is Aromatherapy) and
published first treatise on aromatherapy
in 19371
. Thus, Aromatherapy is defined
as the use of essential oils for therapeutic
purposes.
Aromatherapy has been accepted
as a part of nursing care in the United
Kingdom.Britishnursesareinsuredbythe
Royal College of Nurses to use essential
oils both topically and inhalation for
improved patient care. Lavender oil with
its mild sedative powers is being tested as
a drug replacement to treat older patients
sufferinginsomnia,anxietyanddepression
and to make terminal care patients more
comfortable. In New York hospitals vanilla
oilisreleasedunderpatientā€™snosestohelp
them relax before an MRI scan. Italian
research has shown it to relieve anxiety
and fear.
Modes of essential oil usage
Inhalation for respiratory tract
infections and physiological effect, topical
application for burns, skin and muscular
problems, compress for swellings and
ingestion for intestinal complaints are
some suitable modes. Taking a bath in
water with few drops of some essential oils
isalsoveryuseful.Massagewith1-3%(few
drops) of essential oils in cold pressed
carrier oils (vegetable oils) is another
mode of application of essential oils.
Except lavender and tea tree oils which
are very mild, the essential oil should be
used after dilution in carrier oils or
inhaled directly from a cotton wool or
floatingonthetopofhotwater.Asessential
oils have specific effects they are also used
in various combinations working in
harmony having synergistic effect on the
body.
Natural Product Radiance Vol 4(1) January-February 2005 19
Article
Therapeutics properties of
some essential
oils
Therapeutic
properties of various
essential oils based on
folklore, experiences
and claims of
aromatherapists and
scientific studies have
been summarised in this
review2-20
.
Lavender, Lavandula
angustifolia Mill. syn. L. officinalis
Chaix (Lamiaceae) oil: For centuries
Tea tree (Melaleuca alternifolia)
lavender oil obtained from the flowering
tips of the evergreen shrub, has been used
in perfumes and aromatherapy. Lavender
oil is rich in linalyl acetate, geraniol and
cineole.Itisanaturalantibiotic,antiseptic,
anti-depressant and sedative. It is often
used to treat scalds, minor burns, cuts,
grazes, inflammation, eczema, dermatitis,
headaches, insomnia, acne, dandruff,
boils, rheumatism4
, arthritis, leucorrhoea,
dysmenorrhoea and stretch marks6, 8, 9
.
Lavender reduces anxiety, stress and
tension and therefore it is used for
calming, soothing and relaxation10
. It is
used by way of vapours from oil burners,
massage, bath water and inhaler. A few
drops in a bath of warm water before bed
time will relieve anxiety and alleviate
insomnia while having the bath with cool
waterinstead,willmakeonefeelrefreshed
and energized.
Tea tree, Melaleuca
alternifolia Cheel (Myrtaceae) oil :
It was used as a disinfectant by Australian
soldiers during first world war. It was a
part of the first aid kits of Australian
soldiers for bites and infections during the
second world war. Commercial houses
claimittobethegreatestnaturalantiseptic
of the world. Aromatherapy claims it to
be effective in clearing colds and sour
throat if its vapours are inhaled through
Basil (Ocimum basilicum)
Rose (Rosa damascena)
Eucalyptus (Eucalyptus globulus) Jasmine (Jasminum officinale)
Sandal tree (Santallum album)
Lavender
(Lavendula
officinalis)
Natural Product Radiance Vol 4(1) January-February 200520
Article
steam. Mouth sores and gingivitis can be
checked by the mouth wash made by
putting a few drops of the tea tree oil into
a cup of warm water. It is ascribed with
anti-inflammatory properties. The oil acts
as an antiseptic for treating boils, rashes,
cuts and scrapes as well as insects bites,
stings and carbuncles. It can be applied
directly to the skin. The oil promotes
healing of minor wounds and minimise
any future scarring. It has been shown
effective against Methicillin Resistant
Staphylococcus aureus (MRSA)
bacteria12
.Tea tree oil helps in regulating
Sebum production. A gel containing 5%
tea tree oil has been shown as effective in
the treatment of acne as a lotion with 5%
benzoyl peroxide with far less scaling and
itching13
. A solution containing 0.5% tea
tree oil could offer protection against
Pityrosporum ovale, a common
dandruff causing fungus and head lice. It
could check fungal infection under toe-
nails and bromhidrosis (smelly foot). The
oil has been shown effective against
Candida albicans and Trichomonas
vaginalis, two of the organisms that
cause vaginal infections14
. Tampons
moistened with a few drops of the oil or
its douches for a week are recommended
for this purpose. The oil has been found
effective in chronic cystitis. Cytotoxicity
evaluation of the oil using human cell lines
supports the use of tea tree oil in topical
applications but not for ingestion
purposes15
. Biological activity of tea tree
oil has been recently reviewed16
.
Sandalwood, Santalum
album Linn. (Santalaceae) oil:
Sandalwood oil has been used in Indian
Ayurvedic system for centuries. It is
renowned for its sublime, aphrodisiac,
diuretic and urinary antiseptic properties.
The oil is extracted by steam or
hydrodistillation from roots and wood.
India is the biggest exporter of this oil. It
supports the lymphatic system, nervous
andcardiovascularsystemandrelievesthe
symptoms of sciatica and lumbago. It has
been found to help remove negative
programming from the cells and increases
oxygen around the pituitary and pineal
glands9
. Sandalwood oil removes
depression, anxiety, nervousness, stress
and insomnia. It helps to soften dry,
mature or wrinkled skin. It may also
reduce irritation from hives and other
rashes. Topical application helps remove
acne and herpes. Ī±- and Ī²ā€“Santolol and
santenone are main constituents of the
sandalwood oil. Sandalwood oil has been
shown to have antiviral activity against
Herpes simplex 1 and 2. The essential
oil appeared to interfere with the virusā€™s
ability to replicate17
.
Eucalyptus, Eucalyptus
globulus Labill.(Myrtaceae) oil: The
essential oil from the leaves is rich in
cineole and affects the respiratory system.
It is antibacterial, antifungal, antiviral,
anticatarrhal, mucolytic, expectorant and
antidepressant. Inhalation of the oil is
effective in asthma, bronchitis, colds, flu,
catarrh and sinus infections8
. For this
sprinkle a few drops of the oil on a damp
cloth and hold it close to the nose and
exhale through the mouth for about a
minute. It sooths dry coughs. Topical
application of the dilute oil is effective in
burns, warts, insect bites, lice, herpes and
foot odour9
. It combats skin infections
such as boils and pimples. Mixed with
carrier oil it can be used as a liniment to
reduce swellings and muscle aches and
pains. It promotes alertness, clears the
mind. Eucalyptus oil has been used
successfully from as early as 1789.
Jasmine, Jasminum
officinale Linn. (Oleaceae) oil:
Jasmine was introduced in Europe from
India and Persia. It is best known for
its use in perfumes. Benzyl acetate, linalyl
acetate, geraniol, linalool and jasmone
are its main constituents. It is beneficial
for the skin reducing problems such as
dry, irritated or sensitive skin, muscle
spasms,sprains,laryngitis,dysmenorrhea,
labour pain, frigidity, depression,
and nervous exhaustion. It induces
relaxation9
.
Rose, Rosa Ɨ damascena
Mill. (Rosaceae)oil: Roseoilhasalong
history of medicinal and cosmetic use. It
is perhaps the most precious of all
essential oils obtained by steam
distillation, enfleurage or solvent
extraction form petals. Its invigorating
fragrance is almost intoxicating and
aphrodisiac like. It enhances the
frequency of every cell, bringing balance
and harmony to the body. It is anti-
haemorrhaging, anti-infectious and
prevents scarring. It may help in chronic
bronchitis, conjunctivitis, asthma,
depression, emotional shock, stress18
,
tension, aged and dry skin, frigidity,
impotence, wrinkles, thrush and
gingivitis6, 9
.
Rose oil passeries are being tried
as a contraceptive. It is stimulating and
elevating to the mind, creating a sense of
well being. It is a muscle relaxant. It tones
thecapillaries,improvesbloodcirculation
to the skin surface and revitalises it, thus
refreshing a personā€™s looks and increases
confidence.
Basil, Ocimum basilicum
Linn. (Lamiaceae) oil: Basil is native
of India where it is regarded as a sacred
Natural Product Radiance Vol 4(1) January-February 2005 21
Article
herb and used traditionally in Indian
system of medicine. Now it is grown in
Mediterranean and European countries
also. The essential oil from the leaves and
inflorescence, extracted by steam
distillation, is rich in methyl chavicol and
linalool. It has been found to be beneficial
for alleviating mental fatigue, spasms,
rhinitis, and as a first aid treatment for
wasp stings and snake bites. It may also
help when there is a loss of smell due to
chronic nasal catarrh9
. It can be used as
a mouthwash for relieving toothache. It
has antibacterial and expectorant qualities
apart from being useful in the treatment
of ringworm and some skin diseases.
Coriander, Coriandrum
sativum Linn. (Apiaceae) oil: The
seed oil has anti-inflammatory and
sedative properties9
. A communication
from Cairo University indicates that the oil
lowers glucose levels by normalizing
insulin levels and supporting pancreas
function. The main constituents of the oil
are linalyl acetate, carvacrol and linalool
oxide.
Clove, Syzygium
aromaticum (Linn.) Merrill & Perry
(Myrtaceae) oil: The oil of clove bud is
used as an antiseptic and anesthetic in
mouth infections. It is used in European
hospitals to dental infections. It is also
used in thyroid dysfunction11, 15
. Eugenol
is the main constituent of the oil.
Chamomile, Matricaria
recutita Linn. (Asteraceae) oil: Oil
from the flowers has chamazulene which
gives the oil its classical anti-inflammatory
properties which have been shown
comparable to hydrocortisone19
. It is
renowned for its calming ability and skin
care. It may help in leg cramps, muscle
tension, insomnia and allergies. It
stimulates appetite and combats
diarrhoea. It helps heal acne and reduces
other types of skin inflammation.
Roman chamomile,
Chamaemelum nobile (Linn.) All.
syn. Anthemis nobilis Linn.
(Asteraceae) oil: The oil may also be
used as an anti-inflammatory but it is used
more often in aromatherapy as an
antispasmodic and sedative.
Peppermint, Mentha
piperita Linn. (Lamiaceae) oil: The
mentha oil helps to reduce fevers, nausea,
vomiting and aids in respiratory function.
It helps in headaches, migraines, motion
sickness and sinusitis6, 8
. It helps cooling
the body during hot summer days.
Menthol, menthone and cineole are the
main constituents of the oil.
Petitgrain, Citrus
aurantium Linn. (Rutaceae) oil: The
oil is obtained from the leaves and twigs
of the bitter orange tree. It has a gentle
sedative action on inhalation and is useful
in cases of insomnia and fatigue. It re-
establishes nerve equilibrium. Terpene
alcohols and linalyl acetate are the main
constituents of the oil. Lemon, orange and
other citrus oils improve mood and
increase alertness.
Rosemary, Rosmarinus
officinalis Linn. (Lamiaceae) oil:
The oil is extracted by steam distillation
of leaves and flowering tops. The oil can
be used in arthritic pain6, 8
, asthma,
bronchitis, catarrh, memory loss, mental
fatigue and muscular pain. It may be
beneficialforskinconditionsanddandruff
and may help fight candida and support
immune system. It is a carminative also.
Ī±ā€“Pinene, camphene, borneol, bornyl
acetate,camphorandcineolearethemain
constituents of the oil. Rosemary oil and
its main constituent bicyclic ether 1,
8-cineole act as an activating, refreshing
remedyagainstexhaustion.Thelocomotor
activity of the test animals increased
significantly by inhalation of this ether or
this oil2
. Pregnant ladies, epileptic and
hypertensive persons should avoid its use.
Juniper berry, Juniperus
communis Linn. (Cupressaceae)
oil: Juniper has long been known for its
antiseptic and diuretic properties. The
essential oil is obtained by steam
distillation from the berries. The oil may
work as a detoxifier, astringent and
cleanser, reducing dermatitis, oozing
eczema and acne. It has also been used to
promote better nerve and kidney
function8
. It helps to reduce cellulite.
Ī±ā€“Pinene, sabinene and juniperene are
its important constituents.
Sweet Marjoram, Origanum
majorana Linn. (Lamiaceae) oil: It
is calming to the respiratory system and
assists in relieving spasms and migraine
headaches. It increases peristaltic
movements of intestine. It is soothing to
nerves and works as diuretic8
. Sabinene,
Ī±ā€“terpineol, terpineneā€“4ā€“ol, geraniol and
linalool are the main constituents of the oil.
Thyme, Thymus vulgaris
Linn. (Lamiaceae) oil: It has a
spasmolytic and antiseptic effect and it has
been successfully administered
precutaneously to babies suffering from
pertusis.Thymol,carvacrolandcamphene
are its main constituents. Valnet20
found it
to destroy anthrax and bacillus and a
stronger antiseptic than phenol. Camphor,
borneol, thymol and menthol are said to
possess stronger bactericidal properties
than those of phenol. Borneol was used
as a prophylactic to plague in middle ages.
The active bactericidal constituent of the
Natural Product Radiance Vol 4(1) January-February 200522
Article
essential oil of garlic, allicin, retains its
effect even in dilution of 1:1,25,00. The
oil of wintergreen mainly containing
methyl salicylate is used topically in the
treatment of rheumatism.
Essential oils of Juniper berries
and dwarf pine needles acted in the same
way against exhaustion. Contingent
negative variation (CNV) (it is a slow
upward shift in brain waves recorded by
the electro encephalogram EEG) studies
have showed that jasmine oil brought
about an effect similar to the
administration of caffeine, i.e. an increase
CNV after inhalation where as lavender oil
caused CNV to decrease, similar to the
administration of tranquillizers, thus
leading to a sedation3
.
Antimicrobial and anthelmintic
activities of some essential oil
bearing plants
Anacardium occidentale
Linn. (Anacardiaceae): On
neuropharmacological studies the oil has
been found to be CNS depressant on the
basis of its activity on behaviour, sodium
pentobarbitone induced hypnosis, rota
rod performance, conditioned avoidance
response and pain threshold of albino
rats21
. The oil has shown strong
antibacterial activity against
Pseudomonas mangiferae, P.
aeruginosa, Salmonella sp.,
Bacillus mycorides, Vibrio cholerae
and Xanthomonas campestris 22
.
Artemisia pallens Wall. ex
DC. (Asteraceae): The essential oil has
strong antimicrobial activity against
Escherichia coli, Vibrio cholerae,
Bacillus subtilis, Staphylococcus
aureus, Salmonella typhi,
Aspergillus sp., Chrysosporium
indicum, Trichophyton
mentagrophytes 23
.Theoilhasexhibited
good anthelmitic activity against
Pheritma posthuma (earthworm),
Taenia solium (tape worms) and
Ascaris lumbricoides (round
worms)24
.
Capillipedium foetidium
(Poaceae): The oil has shown strong
antibacterial and antifungal efficacy25
.
Curcuma longa Linn.
(Zingiberaceae): The essential oil is
effective against the conditions caused by
Aspergillus sp., Bacillus subtilis,
Corynebacterium diphtheriae,
Staphylococcus aureus, Salmonella
typhi and Escherichia coli 26
.
Elettaria cardamomum
Maton (Zingiberaceae): The essential
oil contains: cineole, 30.7; limonene,
14.3; and terpenyl acetate, 28.1%.
Bacillus subtilis, Corynebacterium
diphtheriae, Staphylococcus aureus,
Salmonella typhi, Shigella sp.,
Escherichia coli, Aspergillus niger,
A. fumigatus, Rhizopus oryzae,
Fusarium psidi and Curvularia
lunatawerefoundsusceptibletotheoil27
.
Eupatorium triplinerve
Vahl (Asteraceae): The oil from the
flowers is rich in thymohydroquinone
dimethyl ether (50.36%). It has shown
good in vitro efficacy against Bacillus
subtilis, Diplococcus pneumoniae,
Vibrio cholerae and helminths,
Ascaris lumbricoides and Taenia
solium28
.
Feronia limonia (Linn.)
Swingle syn. F. elephantum Correa
(Rutaceae): The essential oil is very rich
in methyl chavicol 68.3%, Escherichia
coli, Pseudomonas aeruginosa,
Shigella shiga, Staphylococcus sp.,
Proteus vulgaris, Trichoderma
virideandTrichophyton rubrum,have
been found susceptible for the oil29
.
Myrtus communis Linn.
(Myrtaceae): The oil from the leaves of
Myrtus communis var. microphylla
caused strong inhibition to the growth of
Trichoderma viride, Candida
albicans, C. utilis and Aspergillus
niger which cause dermatitis30
.
Pavonia odorata Willd.
(Malvaceae): The oil has shown strong
anthelmintic activity against tapeworms
and roundworms24
. Staphylococcus
aureus, Diplococcus pneumoniae,
Trichophyton mentagorophytes,
Chrysosporium indicum and
Botrydiplodia sp. were also reported
susceptible to the oil31
.
Piper betle Linn. cv. ā€˜Sagar
banglaā€™ (Piperaceae): Cultivar ā€˜Sagar
banglaā€™ is highly active against the
Keratinophilic fungi and bacterial
organisms, Bacillus subtilis, B.
pumulus, Staphylococcus aureus,
Salmonella typhi and Vibrio
cholerae.Theessentialoilwasalsofound
to be more effective against tapeworms
(Taenia solium) and hookworms
(Bunostomum trigonocephalum)
than the synthetic anthelmintics,
Piperazine phosphate and Hexyl
resorcinol32
.
Zingiber officinale Rosc.
(Zingiberaceae): The oil has strong
insect repellent activity against,
Periplaneta americana and Bruchus
pisorum33
.
Essentialoilsisolates,cumaldehyde
(Cuminum cyminum Linn.),
1,8-cineole [Luvunga scandens
Natural Product Radiance Vol 4(1) January-February 2005 23
Article
Table 1 : Summary of essential oils used in various diseases/problems
S.No. Diseases/other problems Essential oils
1. Abcesses Lavender, Tea tree.
2. Accumulation of toxins Birch, Carrot seed, Juniper.
3. Acne Bergamot, Chamomile, Geranium, Lavender, Palmarosa,
Patchouli, Sandalwood, Tea tree.
4. Amenorrhoea (missing or scanty period) Basil, Clary sage, Marjoram.
5. Anxiety Lavender, Chamomile, Tea tree, Geranium.
6. Arthritis Birch, Black pepper, Chamomile, Eucalyptus, Ginger, Juniper,
Rosemary.
7. Asthma Clary sage, Cypress, Frankincense, Lavender, Marjoram.
8. Boils Bergamot, Chamomile, Lavender.
9. Bronchial infections (including colds, flu Basil, Benzoin, Cajeput, Cedarwood, Eucalyptus,
and bronchitis) Frankincense, Ginger, Lavender, Marjoram, Myrtle,
Peppermint, Pine needle, Sandalwood, Tea tree, Thyme.
10. Bruises, Burns Fennel, Marjoram.
11. Cold sores Bergamot, Eucalyptus, Tea tree.
12. Constipation Rose, Fennel.
13. Cystitis Bergamot, Lavender, Sandalwood.
14. Dandruff Lavender, Eucalyptus, Tea tree.
15. Depression Basil, Bergamot, Lavender, Lime, Sandalwood.
16. Dermatitis Birch, Chamomile, Lavender, Palmarosa, Basil.
17. Eczema Bergamot, Birch, Chamomile, Lavender, Melissa, Patchouli.
18. Fevers Eucalyptus, Lemongrass.
19. Griping pains Cardamom seeds, Peppermint.
20. Gout Benzoin, Carrot seed, Juniper, Lemon, Rosemary.
21. Insect bites and Stings Basil, Chamomile, Lavender, Tea tree.
22. Insect repellent Lemongrass, Citronella, Lavender.
23. Insomnia Chamomile, Lavender, Marjoram.
(Roxb.) Buch.-Ham. ex Wight],
caryophyllene and eugenol (Ocimum
sanctum Linn.) possess strong activity
against many pathogenic fungal
organisms34
.
A summary of essential oils used
in various problems and diseases is given
in Table 19
.
Natural Product Radiance Vol 4(1) January-February 200524
Article
S.No. Disease/other problems Essential oils
24. High BP Lavender, Ylang Ylang.
25. Leucorrhoea (white vaginal discharge) Bergamot, Lavender, Myrrh.
26. Menopause (hot flushes, mood swings) Cypress, Chamomile, Fennel.
27. Migraine Lavender.
28. Muscular aches and Pains Basil, Black pepper, Chamomile, Eucalyptus, Ginger,
Grapefruit, Lavender, Marjoram, Rosemary.
29. Nausea Cardamom seed, Chamomile.
30. Pruritis Bergamot, Myrrh, Tea tree.
31. Psoriasis Bergamot, Birch.
32. Pyorrhoea Fennel.
33. Haemorrhoids (Piles) Cypress, Parsley seed.
34. Sprains and Strains Chamomile, Lavender.
35. Herpes Tea tree, Sandalwood.
36. Stretch marks Mandarin, Lavender.
37. Rheumatism Benzoin, Birch, Chamomile, Eucalyptus, Ginger, Juniper,
Lavender, Marjoram, Rosemary.
38. Scars Frankincense, Petitgrain, Lavender.
39. Vaginitis Tea tree.
40. Verrucas, Corns and Warts Lemon, Tea tree.
41. Vertigo Lavender, Peppermint.
42. Worms Chenopodium.
Practical guidelines to use
essential oils in some common health
problems are:
ā€¢ Abdominal pain: Add 2 drops of
bitter orange and 2 drops caraway to
2 cups of hot water and inhale the
fragrant vapours. Alternatively add 2
drops of peppermint oil, 2 drops of
bitter orange, and 2 drops of caraway
oil in one teaspoon of a cold pressed
carrieroilandsmooththisgentlyover
the painful area of abdomen in a
clockwise circulatory motion for few
minutes.
ā€¢ Cough: Mix 3 drops of cedar wood,
2 drops peppermint oil and 1 drop of
cajuput oil with 2 teaspoons of olive
oil and massage on to throat and
chest.
ā€¢ Earache: Add 4 drops of lavender,
cajuputorchamomileoilinhalfalitre
of steaming hot water and inhale the
steam for 10 minutes.
ā€¢ Headache (from cold or allergic
rhinitis): Pour 2 drops each of sweet
marjoram, lavender and peppermint
oilsonatissueandinhaledeeply3times.
ā€¢ Nose bleeding: Cypress oil helps
stop blood loss. Put a few drops on a
cotton wool ball and hold under the
nose to stop bleeding.
Natural Product Radiance Vol 4(1) January-February 2005 25
Article
Conclusion
As such there is reasonable
evidence that aromatherapy has scientific
basis and is gaining acceptance under
holistic system of healing. European
physicians and aromatherapists now
frequently prescribe essential oils for a
variety of complaints including colds and
stuffy nose, sinusitis, insomnia, migraine,
muscle aches and pains and digestive
problems.
References
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Aromatherapy [Aromatherapie ā€œ les
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vegetablesā€].TisserandR,Ed.Davies
L translator Saffron Walder (CW
Daniel Co. Ltd., UK), 1993.
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Ammon HPT, Blood levels of 1,8ā€“
cineole and locomotor activity of
mice after inhalation and oral
administration of rosemary oil,
Planta Med, 1987, 53, 315-318.
3. Torii S, Fukuda H, Kanemoto H,
Miyanchi R, Hamauzu Y and
Kawasaki M, Contingent negative
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Hall, London), 1988, 11, 107-120.
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Fritzer M, Percutaneous absorption
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peroxide in the treatment of acne,
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Phytotherapie, 1985, 15, 9-17.
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Markham LJ, In vitro cytotoxicity
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and 2, Phytomedicine, 1999,
6(2), 119-123.
18. Rimmer L, The chemical use of
aromatherapy in the reduction of
stress, Home Healthcare Nurse,
1998, 16(2), 123-126.
19. Aerteets P, Albring M and Klascheka
F, Pharmacological investigations
with compounds of chamomile:
Investigations on the antiphlogistic
effects of chamazulene and
matricine, Planta Med, 1985, 49,
67-73.
20. Valnet J, The practice of
aromatherapy, (Healing Arts Press,
Rochester), 1990.
21. Garg SC and Kasera HL,
Neuropharmacological studies of
essential oil of Anacardium
occidentale, Fitoterapia, 1984,
55 (3), 131-136.
5. Buchbauer G and Jirovetz L,
Aromatherapy ā€“ use of fragrances
and essential oils as medicaments,
Flavour Fragr J, 1994, 9,
217-222.
6. Gwydion Oā€™Hara, The magic of
aromatherapy, (Llewellyn
Publications, St. Paul, Minnesota),
1998.
7. Lawless J, Essential oils, the
complete guide to the use of oils in
aromatherapy and herbalism,
(Element Book Ltd., Dorert,
Massachusetts), 1999.
8. McDermott Alistair (Ed), Curing
everyday ailments ā€“ The natural way,
(Readers Digest, Sydney), 2000,
pp. 31, 331.
9. Singh Babita, Aromatherapy : The
best way to relax using essential oils,
Agric Watch, 2001, 1(4), 50-62.
10. Buckle J, Aromatherapy: What is it,
Herbalgram, 2003, 57, 50-56.
11. Ludvigson H and Rottman T, Effects
of ambient odours of lavender and
cloves on cognition, stress and
mood, Chem Sense, 1989, 14,
525-536.
12. Carson CF, Cookson BD, Farrelly HD
and Riley TV, Susceptibility of
methicillin resistant
Staphylococcus aureus to the
essential oil of Melaleuca
alternifolia, J Antimicrob
Chemother, 1995, 35, 421-424.
13. Bassett IB, Pannowitz DL and
Barnetson RS, A comparative study
of tea tree oil versus benzoyl
Natural Product Radiance Vol 4(1) January-February 200526
Article
22. Garg SC and Kasera HL, Antibacterial
activity of the essential oil of
Anacardium occidentale,
Indian Perfum, 1984, 28(2),
95-97.
23. Nakhare S and Garg SC,
Antimicrobial activity of the essential
oil of Artemisia pallens Wall.,
Indian Perfum, 1996, 40(4),
116-118.
24. Garg SC, Anthelmintic activity of
some medicinal plant products,
In: Recent Progress in Medicinal
Plants Vol. II - Phytochemistry
and Pharmacology, Eds. S Singh,
VK Singh and JN Govil, (Research
Periodicals and Book Publishing
House, Houston), 2003, 207ā€“217.
25. Garg SC and Dangre SL,
Antimicrobial activity of the essential
oil of Capillipedium foetidum,
Pharmazie, 1984, 39(1), 64;
Antifungal efficacy of some essential
oils, 1988, ibid, 43, 141-142.
26. Garg SC and Jain RK, Antimicrobial
activity of the essential oil of
Curcuma longa, Indian
Perfum, 2003, 47(2), 199-202.
27. Garg SC and Jain RK, Antimicrobial
efficacy of essential oil of Elettaria
cardamomum, Indian Perfum,
2001, 45(2), 115-117.
28. Garg SC and Nakhare S, Studies on
the essential oil from flowers of
Eupatorium triplinerve, Indian
Perfum, 1993, 37(4), 318-323.
29. Garg SC, Antimicrobial activity of the
essential oil of Feronia
elephantum Correa, Indian J
Pharm Sci, 2001, 63(2),
155-157.
30. Garg SC and Dengre SL, Antifungal
efficacy of the essential oil of
Myrtus communis, Herba
Hung, 1988, 27 (2ā€“3), 123-125.
31. Garg SC and Nakhare S,
Antimicrobialefficacyofessentialoil
of Pavonia odorata Wild.,
Ancient Sci Life, 1992, 12 (1-2)
227-230.
32. Garg SC and Jain Rajshree,
Biological activity of the essential oil
of Piper betle L. J Essent Oil
Res, 1992, 4, 600-606.
33. Garg SC and Banerjee AK, Insect and
pest control activity of essential oils,
Indian Perfum, 1997, 41(2),
69-80.
34. Garg SC and Siddiqui N, Antifungal
activity of some essential oil isolates,
Pharmazie, 1992, 47, 467-468.
Recently Sara Burt at Department
of Public Health and Food Safety, Faculty
of Veterinary Medicine, University of
Utrecht, The Netherlands has published a
review entitled, ā€˜Essential oils: their
antibacterial properties and potential
applications in foodsā€™ which conclude that
in vitro studies have demonstrated
antibacterial activity of essential oils (EOs)
against Listeria monocytogenes,
Salmonella typhimurium,
Escherichia coli O157:H7, Shigella
dysenteria, Bacillus cereus and
Staphylococcus aureus at levels
between 0.2 and 10 Āµl/ml. Gram negative
organismsareslightlylesssusceptiblethan
Gram positive bacteria. A number of EO
components have been identified as
effective antibacterials, e.g. carvacrol,
thymol, eugenol, perillaldehyde,
cinnamaldehyde and cinnamic acid,
having minimum inhibitory
concentrations (MICs) of 0.05ā€“5 Āµl/ml
in vitro.Ahigherconcentrationisneeded
to achieve the same effect in foods. Studies
with fresh meat, meat products, fish, milk,
dairy products, vegetables, fruit and
cooked rice have shown that the
concentration needed to achieve a
significant antibacterial effect is around
Antibacterial properties and potential
applications of essential oils in foods
0.5ā€“20 Āµl/g in foods and about 0.1ā€“10
Āµl/ml in solutions for washing fruit and
vegetables. Physical conditions that
improve the action of EOs are low pH, low
temperature and low oxygen levels.
Synergism has been observed between
carvacrol and its precursor p-cymene and
between cinnamaldehyde and eugenol.
SynergybetweenEOcomponentsandmild
preservation methods has also been
observed. Some undesirable organoleptic
effects can be limited by careful selection
of EOs according to the type of food [Sara
Burt, Int J Food Microbiol, 2004,
94(3), 223-253].

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How to Use Essential Oils for Common Ailments

  • 1. Natural Product Radiance Vol 4(1) January-February 200518 Article Essential oils as Therapeutics S C Garg Department of Chemistry Dr. Harisingh Gour University, Sagar 470 003, Madhya Pradesh, India E-mail: profscgarg@hotmail.com Abstract Essential oils are the volatile secondary plant metabolites which mainly consist of terpenoids and benzenoids. Research in the later half of 20th century has revealed that many curative properties attributed to various plants in indigenous medicine are also present in their essential oils. These oils exert a number of general effects from the pharmacological viewpoint. When applied locally, the essential oils mix readily with skin oils, allowing these to attack the infective agents quickly and actively. Therapeutic properties of various essential oils based on folklore, experiences and claims of aromatherapists and scientific studies have been summarised in this review. In vitro studies conducted by the author on antimicrobial and anthelmintic properties of some essential oils have also been discussed. Keywords: Essential oils, Therapeutics, Aromatherapy, Antimicrobial, Anthelmintic. IPC Code; Int. cl.7 āŽÆ C11B 9/00, A61P/00, A61P 31/00, A61P 33/10 Introduction Herbal medicines are the gift of ā€˜Mother Natureā€™ to its children, the mankind. The fragrance of myriad flowers and herbs enchants man, elevates the mood and leads to feeling good. Essential oils, the secondary plant metabolites, and the most sublime extractive of plants, found their way from herbal medicine. Inhaling the aromas for therapeutic purposes and then use of essential oils in whatever way they are useful in therapy became the basis of aromatherapy. The recorded history of ancient civilizations indicate the use of aromatic plants like lavender, cedar and cypress for curing ailments, offerings to deities and anointments. In 1928, a French chemist Dr. Rene Gattefosse, while working on essential oils badly burned his hand in laboratory and desperately plunged it into the nearest vat containing lavender oil. He wasastonishedtoseehowquicklythepain ceased having no blisters and the skin healed quickly than normal without forming a scar. Later on he studied the therapeutic benefits of essential oils and coined the word ā€œAromatherapieā€ (the anglicized form is Aromatherapy) and published first treatise on aromatherapy in 19371 . Thus, Aromatherapy is defined as the use of essential oils for therapeutic purposes. Aromatherapy has been accepted as a part of nursing care in the United Kingdom.Britishnursesareinsuredbythe Royal College of Nurses to use essential oils both topically and inhalation for improved patient care. Lavender oil with its mild sedative powers is being tested as a drug replacement to treat older patients sufferinginsomnia,anxietyanddepression and to make terminal care patients more comfortable. In New York hospitals vanilla oilisreleasedunderpatientā€™snosestohelp them relax before an MRI scan. Italian research has shown it to relieve anxiety and fear. Modes of essential oil usage Inhalation for respiratory tract infections and physiological effect, topical application for burns, skin and muscular problems, compress for swellings and ingestion for intestinal complaints are some suitable modes. Taking a bath in water with few drops of some essential oils isalsoveryuseful.Massagewith1-3%(few drops) of essential oils in cold pressed carrier oils (vegetable oils) is another mode of application of essential oils. Except lavender and tea tree oils which are very mild, the essential oil should be used after dilution in carrier oils or inhaled directly from a cotton wool or floatingonthetopofhotwater.Asessential oils have specific effects they are also used in various combinations working in harmony having synergistic effect on the body.
  • 2. Natural Product Radiance Vol 4(1) January-February 2005 19 Article Therapeutics properties of some essential oils Therapeutic properties of various essential oils based on folklore, experiences and claims of aromatherapists and scientific studies have been summarised in this review2-20 . Lavender, Lavandula angustifolia Mill. syn. L. officinalis Chaix (Lamiaceae) oil: For centuries Tea tree (Melaleuca alternifolia) lavender oil obtained from the flowering tips of the evergreen shrub, has been used in perfumes and aromatherapy. Lavender oil is rich in linalyl acetate, geraniol and cineole.Itisanaturalantibiotic,antiseptic, anti-depressant and sedative. It is often used to treat scalds, minor burns, cuts, grazes, inflammation, eczema, dermatitis, headaches, insomnia, acne, dandruff, boils, rheumatism4 , arthritis, leucorrhoea, dysmenorrhoea and stretch marks6, 8, 9 . Lavender reduces anxiety, stress and tension and therefore it is used for calming, soothing and relaxation10 . It is used by way of vapours from oil burners, massage, bath water and inhaler. A few drops in a bath of warm water before bed time will relieve anxiety and alleviate insomnia while having the bath with cool waterinstead,willmakeonefeelrefreshed and energized. Tea tree, Melaleuca alternifolia Cheel (Myrtaceae) oil : It was used as a disinfectant by Australian soldiers during first world war. It was a part of the first aid kits of Australian soldiers for bites and infections during the second world war. Commercial houses claimittobethegreatestnaturalantiseptic of the world. Aromatherapy claims it to be effective in clearing colds and sour throat if its vapours are inhaled through Basil (Ocimum basilicum) Rose (Rosa damascena) Eucalyptus (Eucalyptus globulus) Jasmine (Jasminum officinale) Sandal tree (Santallum album) Lavender (Lavendula officinalis)
  • 3. Natural Product Radiance Vol 4(1) January-February 200520 Article steam. Mouth sores and gingivitis can be checked by the mouth wash made by putting a few drops of the tea tree oil into a cup of warm water. It is ascribed with anti-inflammatory properties. The oil acts as an antiseptic for treating boils, rashes, cuts and scrapes as well as insects bites, stings and carbuncles. It can be applied directly to the skin. The oil promotes healing of minor wounds and minimise any future scarring. It has been shown effective against Methicillin Resistant Staphylococcus aureus (MRSA) bacteria12 .Tea tree oil helps in regulating Sebum production. A gel containing 5% tea tree oil has been shown as effective in the treatment of acne as a lotion with 5% benzoyl peroxide with far less scaling and itching13 . A solution containing 0.5% tea tree oil could offer protection against Pityrosporum ovale, a common dandruff causing fungus and head lice. It could check fungal infection under toe- nails and bromhidrosis (smelly foot). The oil has been shown effective against Candida albicans and Trichomonas vaginalis, two of the organisms that cause vaginal infections14 . Tampons moistened with a few drops of the oil or its douches for a week are recommended for this purpose. The oil has been found effective in chronic cystitis. Cytotoxicity evaluation of the oil using human cell lines supports the use of tea tree oil in topical applications but not for ingestion purposes15 . Biological activity of tea tree oil has been recently reviewed16 . Sandalwood, Santalum album Linn. (Santalaceae) oil: Sandalwood oil has been used in Indian Ayurvedic system for centuries. It is renowned for its sublime, aphrodisiac, diuretic and urinary antiseptic properties. The oil is extracted by steam or hydrodistillation from roots and wood. India is the biggest exporter of this oil. It supports the lymphatic system, nervous andcardiovascularsystemandrelievesthe symptoms of sciatica and lumbago. It has been found to help remove negative programming from the cells and increases oxygen around the pituitary and pineal glands9 . Sandalwood oil removes depression, anxiety, nervousness, stress and insomnia. It helps to soften dry, mature or wrinkled skin. It may also reduce irritation from hives and other rashes. Topical application helps remove acne and herpes. Ī±- and Ī²ā€“Santolol and santenone are main constituents of the sandalwood oil. Sandalwood oil has been shown to have antiviral activity against Herpes simplex 1 and 2. The essential oil appeared to interfere with the virusā€™s ability to replicate17 . Eucalyptus, Eucalyptus globulus Labill.(Myrtaceae) oil: The essential oil from the leaves is rich in cineole and affects the respiratory system. It is antibacterial, antifungal, antiviral, anticatarrhal, mucolytic, expectorant and antidepressant. Inhalation of the oil is effective in asthma, bronchitis, colds, flu, catarrh and sinus infections8 . For this sprinkle a few drops of the oil on a damp cloth and hold it close to the nose and exhale through the mouth for about a minute. It sooths dry coughs. Topical application of the dilute oil is effective in burns, warts, insect bites, lice, herpes and foot odour9 . It combats skin infections such as boils and pimples. Mixed with carrier oil it can be used as a liniment to reduce swellings and muscle aches and pains. It promotes alertness, clears the mind. Eucalyptus oil has been used successfully from as early as 1789. Jasmine, Jasminum officinale Linn. (Oleaceae) oil: Jasmine was introduced in Europe from India and Persia. It is best known for its use in perfumes. Benzyl acetate, linalyl acetate, geraniol, linalool and jasmone are its main constituents. It is beneficial for the skin reducing problems such as dry, irritated or sensitive skin, muscle spasms,sprains,laryngitis,dysmenorrhea, labour pain, frigidity, depression, and nervous exhaustion. It induces relaxation9 . Rose, Rosa Ɨ damascena Mill. (Rosaceae)oil: Roseoilhasalong history of medicinal and cosmetic use. It is perhaps the most precious of all essential oils obtained by steam distillation, enfleurage or solvent extraction form petals. Its invigorating fragrance is almost intoxicating and aphrodisiac like. It enhances the frequency of every cell, bringing balance and harmony to the body. It is anti- haemorrhaging, anti-infectious and prevents scarring. It may help in chronic bronchitis, conjunctivitis, asthma, depression, emotional shock, stress18 , tension, aged and dry skin, frigidity, impotence, wrinkles, thrush and gingivitis6, 9 . Rose oil passeries are being tried as a contraceptive. It is stimulating and elevating to the mind, creating a sense of well being. It is a muscle relaxant. It tones thecapillaries,improvesbloodcirculation to the skin surface and revitalises it, thus refreshing a personā€™s looks and increases confidence. Basil, Ocimum basilicum Linn. (Lamiaceae) oil: Basil is native of India where it is regarded as a sacred
  • 4. Natural Product Radiance Vol 4(1) January-February 2005 21 Article herb and used traditionally in Indian system of medicine. Now it is grown in Mediterranean and European countries also. The essential oil from the leaves and inflorescence, extracted by steam distillation, is rich in methyl chavicol and linalool. It has been found to be beneficial for alleviating mental fatigue, spasms, rhinitis, and as a first aid treatment for wasp stings and snake bites. It may also help when there is a loss of smell due to chronic nasal catarrh9 . It can be used as a mouthwash for relieving toothache. It has antibacterial and expectorant qualities apart from being useful in the treatment of ringworm and some skin diseases. Coriander, Coriandrum sativum Linn. (Apiaceae) oil: The seed oil has anti-inflammatory and sedative properties9 . A communication from Cairo University indicates that the oil lowers glucose levels by normalizing insulin levels and supporting pancreas function. The main constituents of the oil are linalyl acetate, carvacrol and linalool oxide. Clove, Syzygium aromaticum (Linn.) Merrill & Perry (Myrtaceae) oil: The oil of clove bud is used as an antiseptic and anesthetic in mouth infections. It is used in European hospitals to dental infections. It is also used in thyroid dysfunction11, 15 . Eugenol is the main constituent of the oil. Chamomile, Matricaria recutita Linn. (Asteraceae) oil: Oil from the flowers has chamazulene which gives the oil its classical anti-inflammatory properties which have been shown comparable to hydrocortisone19 . It is renowned for its calming ability and skin care. It may help in leg cramps, muscle tension, insomnia and allergies. It stimulates appetite and combats diarrhoea. It helps heal acne and reduces other types of skin inflammation. Roman chamomile, Chamaemelum nobile (Linn.) All. syn. Anthemis nobilis Linn. (Asteraceae) oil: The oil may also be used as an anti-inflammatory but it is used more often in aromatherapy as an antispasmodic and sedative. Peppermint, Mentha piperita Linn. (Lamiaceae) oil: The mentha oil helps to reduce fevers, nausea, vomiting and aids in respiratory function. It helps in headaches, migraines, motion sickness and sinusitis6, 8 . It helps cooling the body during hot summer days. Menthol, menthone and cineole are the main constituents of the oil. Petitgrain, Citrus aurantium Linn. (Rutaceae) oil: The oil is obtained from the leaves and twigs of the bitter orange tree. It has a gentle sedative action on inhalation and is useful in cases of insomnia and fatigue. It re- establishes nerve equilibrium. Terpene alcohols and linalyl acetate are the main constituents of the oil. Lemon, orange and other citrus oils improve mood and increase alertness. Rosemary, Rosmarinus officinalis Linn. (Lamiaceae) oil: The oil is extracted by steam distillation of leaves and flowering tops. The oil can be used in arthritic pain6, 8 , asthma, bronchitis, catarrh, memory loss, mental fatigue and muscular pain. It may be beneficialforskinconditionsanddandruff and may help fight candida and support immune system. It is a carminative also. Ī±ā€“Pinene, camphene, borneol, bornyl acetate,camphorandcineolearethemain constituents of the oil. Rosemary oil and its main constituent bicyclic ether 1, 8-cineole act as an activating, refreshing remedyagainstexhaustion.Thelocomotor activity of the test animals increased significantly by inhalation of this ether or this oil2 . Pregnant ladies, epileptic and hypertensive persons should avoid its use. Juniper berry, Juniperus communis Linn. (Cupressaceae) oil: Juniper has long been known for its antiseptic and diuretic properties. The essential oil is obtained by steam distillation from the berries. The oil may work as a detoxifier, astringent and cleanser, reducing dermatitis, oozing eczema and acne. It has also been used to promote better nerve and kidney function8 . It helps to reduce cellulite. Ī±ā€“Pinene, sabinene and juniperene are its important constituents. Sweet Marjoram, Origanum majorana Linn. (Lamiaceae) oil: It is calming to the respiratory system and assists in relieving spasms and migraine headaches. It increases peristaltic movements of intestine. It is soothing to nerves and works as diuretic8 . Sabinene, Ī±ā€“terpineol, terpineneā€“4ā€“ol, geraniol and linalool are the main constituents of the oil. Thyme, Thymus vulgaris Linn. (Lamiaceae) oil: It has a spasmolytic and antiseptic effect and it has been successfully administered precutaneously to babies suffering from pertusis.Thymol,carvacrolandcamphene are its main constituents. Valnet20 found it to destroy anthrax and bacillus and a stronger antiseptic than phenol. Camphor, borneol, thymol and menthol are said to possess stronger bactericidal properties than those of phenol. Borneol was used as a prophylactic to plague in middle ages. The active bactericidal constituent of the
  • 5. Natural Product Radiance Vol 4(1) January-February 200522 Article essential oil of garlic, allicin, retains its effect even in dilution of 1:1,25,00. The oil of wintergreen mainly containing methyl salicylate is used topically in the treatment of rheumatism. Essential oils of Juniper berries and dwarf pine needles acted in the same way against exhaustion. Contingent negative variation (CNV) (it is a slow upward shift in brain waves recorded by the electro encephalogram EEG) studies have showed that jasmine oil brought about an effect similar to the administration of caffeine, i.e. an increase CNV after inhalation where as lavender oil caused CNV to decrease, similar to the administration of tranquillizers, thus leading to a sedation3 . Antimicrobial and anthelmintic activities of some essential oil bearing plants Anacardium occidentale Linn. (Anacardiaceae): On neuropharmacological studies the oil has been found to be CNS depressant on the basis of its activity on behaviour, sodium pentobarbitone induced hypnosis, rota rod performance, conditioned avoidance response and pain threshold of albino rats21 . The oil has shown strong antibacterial activity against Pseudomonas mangiferae, P. aeruginosa, Salmonella sp., Bacillus mycorides, Vibrio cholerae and Xanthomonas campestris 22 . Artemisia pallens Wall. ex DC. (Asteraceae): The essential oil has strong antimicrobial activity against Escherichia coli, Vibrio cholerae, Bacillus subtilis, Staphylococcus aureus, Salmonella typhi, Aspergillus sp., Chrysosporium indicum, Trichophyton mentagrophytes 23 .Theoilhasexhibited good anthelmitic activity against Pheritma posthuma (earthworm), Taenia solium (tape worms) and Ascaris lumbricoides (round worms)24 . Capillipedium foetidium (Poaceae): The oil has shown strong antibacterial and antifungal efficacy25 . Curcuma longa Linn. (Zingiberaceae): The essential oil is effective against the conditions caused by Aspergillus sp., Bacillus subtilis, Corynebacterium diphtheriae, Staphylococcus aureus, Salmonella typhi and Escherichia coli 26 . Elettaria cardamomum Maton (Zingiberaceae): The essential oil contains: cineole, 30.7; limonene, 14.3; and terpenyl acetate, 28.1%. Bacillus subtilis, Corynebacterium diphtheriae, Staphylococcus aureus, Salmonella typhi, Shigella sp., Escherichia coli, Aspergillus niger, A. fumigatus, Rhizopus oryzae, Fusarium psidi and Curvularia lunatawerefoundsusceptibletotheoil27 . Eupatorium triplinerve Vahl (Asteraceae): The oil from the flowers is rich in thymohydroquinone dimethyl ether (50.36%). It has shown good in vitro efficacy against Bacillus subtilis, Diplococcus pneumoniae, Vibrio cholerae and helminths, Ascaris lumbricoides and Taenia solium28 . Feronia limonia (Linn.) Swingle syn. F. elephantum Correa (Rutaceae): The essential oil is very rich in methyl chavicol 68.3%, Escherichia coli, Pseudomonas aeruginosa, Shigella shiga, Staphylococcus sp., Proteus vulgaris, Trichoderma virideandTrichophyton rubrum,have been found susceptible for the oil29 . Myrtus communis Linn. (Myrtaceae): The oil from the leaves of Myrtus communis var. microphylla caused strong inhibition to the growth of Trichoderma viride, Candida albicans, C. utilis and Aspergillus niger which cause dermatitis30 . Pavonia odorata Willd. (Malvaceae): The oil has shown strong anthelmintic activity against tapeworms and roundworms24 . Staphylococcus aureus, Diplococcus pneumoniae, Trichophyton mentagorophytes, Chrysosporium indicum and Botrydiplodia sp. were also reported susceptible to the oil31 . Piper betle Linn. cv. ā€˜Sagar banglaā€™ (Piperaceae): Cultivar ā€˜Sagar banglaā€™ is highly active against the Keratinophilic fungi and bacterial organisms, Bacillus subtilis, B. pumulus, Staphylococcus aureus, Salmonella typhi and Vibrio cholerae.Theessentialoilwasalsofound to be more effective against tapeworms (Taenia solium) and hookworms (Bunostomum trigonocephalum) than the synthetic anthelmintics, Piperazine phosphate and Hexyl resorcinol32 . Zingiber officinale Rosc. (Zingiberaceae): The oil has strong insect repellent activity against, Periplaneta americana and Bruchus pisorum33 . Essentialoilsisolates,cumaldehyde (Cuminum cyminum Linn.), 1,8-cineole [Luvunga scandens
  • 6. Natural Product Radiance Vol 4(1) January-February 2005 23 Article Table 1 : Summary of essential oils used in various diseases/problems S.No. Diseases/other problems Essential oils 1. Abcesses Lavender, Tea tree. 2. Accumulation of toxins Birch, Carrot seed, Juniper. 3. Acne Bergamot, Chamomile, Geranium, Lavender, Palmarosa, Patchouli, Sandalwood, Tea tree. 4. Amenorrhoea (missing or scanty period) Basil, Clary sage, Marjoram. 5. Anxiety Lavender, Chamomile, Tea tree, Geranium. 6. Arthritis Birch, Black pepper, Chamomile, Eucalyptus, Ginger, Juniper, Rosemary. 7. Asthma Clary sage, Cypress, Frankincense, Lavender, Marjoram. 8. Boils Bergamot, Chamomile, Lavender. 9. Bronchial infections (including colds, flu Basil, Benzoin, Cajeput, Cedarwood, Eucalyptus, and bronchitis) Frankincense, Ginger, Lavender, Marjoram, Myrtle, Peppermint, Pine needle, Sandalwood, Tea tree, Thyme. 10. Bruises, Burns Fennel, Marjoram. 11. Cold sores Bergamot, Eucalyptus, Tea tree. 12. Constipation Rose, Fennel. 13. Cystitis Bergamot, Lavender, Sandalwood. 14. Dandruff Lavender, Eucalyptus, Tea tree. 15. Depression Basil, Bergamot, Lavender, Lime, Sandalwood. 16. Dermatitis Birch, Chamomile, Lavender, Palmarosa, Basil. 17. Eczema Bergamot, Birch, Chamomile, Lavender, Melissa, Patchouli. 18. Fevers Eucalyptus, Lemongrass. 19. Griping pains Cardamom seeds, Peppermint. 20. Gout Benzoin, Carrot seed, Juniper, Lemon, Rosemary. 21. Insect bites and Stings Basil, Chamomile, Lavender, Tea tree. 22. Insect repellent Lemongrass, Citronella, Lavender. 23. Insomnia Chamomile, Lavender, Marjoram. (Roxb.) Buch.-Ham. ex Wight], caryophyllene and eugenol (Ocimum sanctum Linn.) possess strong activity against many pathogenic fungal organisms34 . A summary of essential oils used in various problems and diseases is given in Table 19 .
  • 7. Natural Product Radiance Vol 4(1) January-February 200524 Article S.No. Disease/other problems Essential oils 24. High BP Lavender, Ylang Ylang. 25. Leucorrhoea (white vaginal discharge) Bergamot, Lavender, Myrrh. 26. Menopause (hot flushes, mood swings) Cypress, Chamomile, Fennel. 27. Migraine Lavender. 28. Muscular aches and Pains Basil, Black pepper, Chamomile, Eucalyptus, Ginger, Grapefruit, Lavender, Marjoram, Rosemary. 29. Nausea Cardamom seed, Chamomile. 30. Pruritis Bergamot, Myrrh, Tea tree. 31. Psoriasis Bergamot, Birch. 32. Pyorrhoea Fennel. 33. Haemorrhoids (Piles) Cypress, Parsley seed. 34. Sprains and Strains Chamomile, Lavender. 35. Herpes Tea tree, Sandalwood. 36. Stretch marks Mandarin, Lavender. 37. Rheumatism Benzoin, Birch, Chamomile, Eucalyptus, Ginger, Juniper, Lavender, Marjoram, Rosemary. 38. Scars Frankincense, Petitgrain, Lavender. 39. Vaginitis Tea tree. 40. Verrucas, Corns and Warts Lemon, Tea tree. 41. Vertigo Lavender, Peppermint. 42. Worms Chenopodium. Practical guidelines to use essential oils in some common health problems are: ā€¢ Abdominal pain: Add 2 drops of bitter orange and 2 drops caraway to 2 cups of hot water and inhale the fragrant vapours. Alternatively add 2 drops of peppermint oil, 2 drops of bitter orange, and 2 drops of caraway oil in one teaspoon of a cold pressed carrieroilandsmooththisgentlyover the painful area of abdomen in a clockwise circulatory motion for few minutes. ā€¢ Cough: Mix 3 drops of cedar wood, 2 drops peppermint oil and 1 drop of cajuput oil with 2 teaspoons of olive oil and massage on to throat and chest. ā€¢ Earache: Add 4 drops of lavender, cajuputorchamomileoilinhalfalitre of steaming hot water and inhale the steam for 10 minutes. ā€¢ Headache (from cold or allergic rhinitis): Pour 2 drops each of sweet marjoram, lavender and peppermint oilsonatissueandinhaledeeply3times. ā€¢ Nose bleeding: Cypress oil helps stop blood loss. Put a few drops on a cotton wool ball and hold under the nose to stop bleeding.
  • 8. Natural Product Radiance Vol 4(1) January-February 2005 25 Article Conclusion As such there is reasonable evidence that aromatherapy has scientific basis and is gaining acceptance under holistic system of healing. European physicians and aromatherapists now frequently prescribe essential oils for a variety of complaints including colds and stuffy nose, sinusitis, insomnia, migraine, muscle aches and pains and digestive problems. References 1. Gattefosse M, Gattefosseā€™s Aromatherapy [Aromatherapie ā€œ les huiles esentieles hormones vegetablesā€].TisserandR,Ed.Davies L translator Saffron Walder (CW Daniel Co. Ltd., UK), 1993. 2. Kovar KA, Gropper B, Fries D and Ammon HPT, Blood levels of 1,8ā€“ cineole and locomotor activity of mice after inhalation and oral administration of rosemary oil, Planta Med, 1987, 53, 315-318. 3. Torii S, Fukuda H, Kanemoto H, Miyanchi R, Hamauzu Y and Kawasaki M, Contingent negative variation (CNV) and the psychological effects of odour, In: Perfumery, The Psychology and Biology of Fragrance. St Van Toller and GH Dodd, eds. (Chapman & Hall, London), 1988, 11, 107-120. 4. JagerW,BuchbauerG,JirovetaLand Fritzer M, Percutaneous absorption of lavender oil for a massage oil, J Soc Cosmet Chem, 1992, 43(1), 49-54. peroxide in the treatment of acne, Med J Aust, 1990, 153, 455-458. 14. Belaiche P, Treatment of skin and vaginal infections with the essential oil of Melaleuca alternifolia, Phytotherapie, 1985, 15, 9-17. 15. Hayes AJ, Leach David N and Markham LJ, In vitro cytotoxicity of Australian tea tree oil using human cell lines, J Essent Oil Res, 1997, 9(5), 575-582. 16. Garg SC, A review on biological activity of the tea tree oil, Indian Perfum, 2004, 48(2), 195-197. 17. Benevicca F and Courreges M, Antiviral activity of sandalwood oil against Herpes simplex viruses 1 and 2, Phytomedicine, 1999, 6(2), 119-123. 18. Rimmer L, The chemical use of aromatherapy in the reduction of stress, Home Healthcare Nurse, 1998, 16(2), 123-126. 19. Aerteets P, Albring M and Klascheka F, Pharmacological investigations with compounds of chamomile: Investigations on the antiphlogistic effects of chamazulene and matricine, Planta Med, 1985, 49, 67-73. 20. Valnet J, The practice of aromatherapy, (Healing Arts Press, Rochester), 1990. 21. Garg SC and Kasera HL, Neuropharmacological studies of essential oil of Anacardium occidentale, Fitoterapia, 1984, 55 (3), 131-136. 5. Buchbauer G and Jirovetz L, Aromatherapy ā€“ use of fragrances and essential oils as medicaments, Flavour Fragr J, 1994, 9, 217-222. 6. Gwydion Oā€™Hara, The magic of aromatherapy, (Llewellyn Publications, St. Paul, Minnesota), 1998. 7. Lawless J, Essential oils, the complete guide to the use of oils in aromatherapy and herbalism, (Element Book Ltd., Dorert, Massachusetts), 1999. 8. McDermott Alistair (Ed), Curing everyday ailments ā€“ The natural way, (Readers Digest, Sydney), 2000, pp. 31, 331. 9. Singh Babita, Aromatherapy : The best way to relax using essential oils, Agric Watch, 2001, 1(4), 50-62. 10. Buckle J, Aromatherapy: What is it, Herbalgram, 2003, 57, 50-56. 11. Ludvigson H and Rottman T, Effects of ambient odours of lavender and cloves on cognition, stress and mood, Chem Sense, 1989, 14, 525-536. 12. Carson CF, Cookson BD, Farrelly HD and Riley TV, Susceptibility of methicillin resistant Staphylococcus aureus to the essential oil of Melaleuca alternifolia, J Antimicrob Chemother, 1995, 35, 421-424. 13. Bassett IB, Pannowitz DL and Barnetson RS, A comparative study of tea tree oil versus benzoyl
  • 9. Natural Product Radiance Vol 4(1) January-February 200526 Article 22. Garg SC and Kasera HL, Antibacterial activity of the essential oil of Anacardium occidentale, Indian Perfum, 1984, 28(2), 95-97. 23. Nakhare S and Garg SC, Antimicrobial activity of the essential oil of Artemisia pallens Wall., Indian Perfum, 1996, 40(4), 116-118. 24. Garg SC, Anthelmintic activity of some medicinal plant products, In: Recent Progress in Medicinal Plants Vol. II - Phytochemistry and Pharmacology, Eds. S Singh, VK Singh and JN Govil, (Research Periodicals and Book Publishing House, Houston), 2003, 207ā€“217. 25. Garg SC and Dangre SL, Antimicrobial activity of the essential oil of Capillipedium foetidum, Pharmazie, 1984, 39(1), 64; Antifungal efficacy of some essential oils, 1988, ibid, 43, 141-142. 26. Garg SC and Jain RK, Antimicrobial activity of the essential oil of Curcuma longa, Indian Perfum, 2003, 47(2), 199-202. 27. Garg SC and Jain RK, Antimicrobial efficacy of essential oil of Elettaria cardamomum, Indian Perfum, 2001, 45(2), 115-117. 28. Garg SC and Nakhare S, Studies on the essential oil from flowers of Eupatorium triplinerve, Indian Perfum, 1993, 37(4), 318-323. 29. Garg SC, Antimicrobial activity of the essential oil of Feronia elephantum Correa, Indian J Pharm Sci, 2001, 63(2), 155-157. 30. Garg SC and Dengre SL, Antifungal efficacy of the essential oil of Myrtus communis, Herba Hung, 1988, 27 (2ā€“3), 123-125. 31. Garg SC and Nakhare S, Antimicrobialefficacyofessentialoil of Pavonia odorata Wild., Ancient Sci Life, 1992, 12 (1-2) 227-230. 32. Garg SC and Jain Rajshree, Biological activity of the essential oil of Piper betle L. J Essent Oil Res, 1992, 4, 600-606. 33. Garg SC and Banerjee AK, Insect and pest control activity of essential oils, Indian Perfum, 1997, 41(2), 69-80. 34. Garg SC and Siddiqui N, Antifungal activity of some essential oil isolates, Pharmazie, 1992, 47, 467-468. Recently Sara Burt at Department of Public Health and Food Safety, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands has published a review entitled, ā€˜Essential oils: their antibacterial properties and potential applications in foodsā€™ which conclude that in vitro studies have demonstrated antibacterial activity of essential oils (EOs) against Listeria monocytogenes, Salmonella typhimurium, Escherichia coli O157:H7, Shigella dysenteria, Bacillus cereus and Staphylococcus aureus at levels between 0.2 and 10 Āµl/ml. Gram negative organismsareslightlylesssusceptiblethan Gram positive bacteria. A number of EO components have been identified as effective antibacterials, e.g. carvacrol, thymol, eugenol, perillaldehyde, cinnamaldehyde and cinnamic acid, having minimum inhibitory concentrations (MICs) of 0.05ā€“5 Āµl/ml in vitro.Ahigherconcentrationisneeded to achieve the same effect in foods. Studies with fresh meat, meat products, fish, milk, dairy products, vegetables, fruit and cooked rice have shown that the concentration needed to achieve a significant antibacterial effect is around Antibacterial properties and potential applications of essential oils in foods 0.5ā€“20 Āµl/g in foods and about 0.1ā€“10 Āµl/ml in solutions for washing fruit and vegetables. Physical conditions that improve the action of EOs are low pH, low temperature and low oxygen levels. Synergism has been observed between carvacrol and its precursor p-cymene and between cinnamaldehyde and eugenol. SynergybetweenEOcomponentsandmild preservation methods has also been observed. Some undesirable organoleptic effects can be limited by careful selection of EOs according to the type of food [Sara Burt, Int J Food Microbiol, 2004, 94(3), 223-253].