Puritan's Pride Zinc For Acne supplement may help people control their breakouts, but can also have side effects as well. The most common side effect is increased acne as zinc has been shown in studies to increase testosterone. Testosterone is the androgen responsible for the development of pimples. On the other hand, if you are deficient in zinc you may also have skin problems as well as fatigue and trouble concentrating. This product could be beneficial for someone's skin who does not get enough zinc in their diet.