Diabetic neuropathy.pptx
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Diabetic neuropathy can cause significant burden through pain, loss of function, and independence. It is caused by factors like high blood glucose, vascular damage, and inflammation damaging the nerves over time. The condition is growing as the number of diabetes patients increases. Screening tests evaluate sensation, and medications can help manage neuropathic pain, with treatments customized to each individual.
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It is the group of metabolic disorders which characterised by hyperglycemia and abnormalities of carbohydrate, fat and protein metabolism. resulting from defects in insulin secretion, insulin action, or. Both .
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Life style
Genetics factor
Obesity
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Type :-1 Diabetes (insulin dependent)
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The exact cause of type 1 diabetes is unknown. Usually, the body's own immune system — which normally fights harmful bacteria and viruses — mistakenly destroys cells which the insulin-producing (islets of Langerhans) cells in the pancreas. Other possible causes include:
Genetics
Exposure to viruses and other environmental factors
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Causes:-
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Type :-1 Diabetes (insulin dependent)
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Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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Diabetic neuropathy.pptx
- 1. DIABETIC NEUROPATHY: PROBLEMS, CAUSES AND SOLUTIONS
- 2. DIABETIC NEUROPATHY CAN BE DEFINED AS: • “The presence of symptoms and/or signs of peripheral nerve dysfunction in people with diabetes after other causes have been excluded”
- 5. BURDEN OF DIABETES NEUROPATHY Cost to the Patient: Pain Loss of function Depression Loss of independence Loss of earnings Cost to society: Number of patients growing of Diabetes (Diabetic Capital-world) Workforce Increasing prevalence across all age groups
- 18. WHAT CAUSES DIABETIC NEUROPATHIES? • Metabolic factors - such as high blood glucose, long duration of diabetes, abnormal blood fat levels, and possibly low levels of insulin • Neurovascular factors, leading to damage to the blood vessels that carry oxygen and nutrients to nerves • Autoimmune factors that cause inflammation in nerves • Mechanical injury to nerves • Lifestyle factors, such as smoking or alcohol use
- 25. DIABETIC PERIPHERAL NEUROPATHY SCREENING TESTS • Test sensation • Biothesiometer • Tuning fork • 10 gm monofilament • Ankle reflexes
- 37. PAIN MANAGEMENT MEDICATIONS IN DPN Arch Gen Intern Med. 2018;2(4):1-5. DOI: 10.4066/ 2591-7951.1000060
- 38. ALGORITHM FOR THE TREATMENT OF DIABETIC PAINFUL NEUROPATHY VOLUME 11, ISSUE 6, P521-534, JUNE 01, 2012,DOI:https://doi.org/10.1016/S1474-4422(12)70065-0
- 41. CUSTOMISING TREATMENT The search for pain management