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MANTLE CELL LYMPHOMA:
PRESENTED BY : Maria Mohammad
Content writer
DEFINITION:
 Mantle cell lymphoma (MCL) is a type of
NHL. It develops when B-cells (also called B-
lymphocytes) become abnormal. B-cells are
white blood cells that fight infection.
 The abnormal B-cells (lymphoma cells) usually
build up in lymph nodes, but they can affect
other parts of the body.
SYMPTOMS:
DIAGNOSIS:
 Blood test
 Biopsy
 x-rays and scans
 bone marrow samples
 Colonoscopy
TREATMENT:
 Currently no treatment is available for
advanced MCL.
 Chemotherapy: (e.g : R-CHOP)
 Radiotherapy: Use high energy rays to
destroy cancer cells.
 Immunotherapy: (e.g: Rituximab,
Thalidomide)
 Radioimmunotherapy: (e.g: Zevalin)
 Stem cell transplantation
 Proteasome inhibitors
 Other biological agents: ( Temsirolimus)

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Mantle cell lymphoma

  • 1. MANTLE CELL LYMPHOMA: PRESENTED BY : Maria Mohammad Content writer
  • 2. DEFINITION:  Mantle cell lymphoma (MCL) is a type of NHL. It develops when B-cells (also called B- lymphocytes) become abnormal. B-cells are white blood cells that fight infection.  The abnormal B-cells (lymphoma cells) usually build up in lymph nodes, but they can affect other parts of the body.
  • 4. DIAGNOSIS:  Blood test  Biopsy  x-rays and scans  bone marrow samples  Colonoscopy
  • 5. TREATMENT:  Currently no treatment is available for advanced MCL.  Chemotherapy: (e.g : R-CHOP)  Radiotherapy: Use high energy rays to destroy cancer cells.  Immunotherapy: (e.g: Rituximab, Thalidomide)  Radioimmunotherapy: (e.g: Zevalin)
  • 6.  Stem cell transplantation  Proteasome inhibitors  Other biological agents: ( Temsirolimus)