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Emergency drugs for critical care
- 1. EMERGENCY DRUGS PRESENTED BY : MANU MEHTA ROLL NO : 14 BASIC B.Sc NURSING 3rd YEAR
- 3. *EPINEPHRINE GENERIC NAME : Epinephrine Hydrochloride TRADE NAME : Adrenaclick , primatene mist CHEMICAL CLASS : Catecholamine FUNCTIONAL CLASS : Bronchodilator , nonselective adrenergic agonist MECHANISM OF ACTION
- 4. Decrease firing of carotid and aortic baroreceptors Cardiovascular control center in medulla Increase sympatheti c output Decreases parasympathetic output Increase heart rate
- 5. Vasoconstri ction Increas e force of contrac tion Increase heart rate Increase PVR Increase cardiac output Increase blood pressure to normal
- 6. FUROSEMIDE TREDE NAME : Lasix CHEMICAL CLASS : Sulfonamide derivative FUNCTIONAL CLASS : Loop diuretic MECHANISM OF ACTION Furosemide Ascending loop of henle Acts on And inhibit
- 7. Na+ k+ 2cl - cotransport Inhibition of reabsorption of sodium and chloride Decrease BP , edema with CHF Leads to Leads to
- 8. SODIUM BICARBONATE TRADE NAME : Sodabicarb , Baking Soda CHEMICAL CLASS : NaHco3 FUNCTIONAL CLASS: Antacid Sodium bicarbonate MECHANISM OF ACTION Water , Na+ , Co2 Breaks into
- 9. Increase plasma bicarbonate level Buffers H+ ion concentration Neutralizes gastric acid
- 10. DOPAMINE GENERIC NAME : Dopamine hydrochloride TRADE NAME : Dopamine , CHEMICAL CLASS : Catecholamine FUNCTIONAL CLASS : Adrenergic MECHANISM OF ACTION Dopamine In low dose In high dose
- 11. D1 and D2 receptors Acts on Alpha and beta1 receptors Vasodilation of renal and mesentric artery Vasoconstrictio n and increase cardiac output Increase renal blood flow Increase blood flow Acts on Leads to Leads to
- 12. DOBUTAMINE TRADE NAME : Dobutrex , Dobuject GENARIC NAME : Dobutamine hydrochloride CHEMICAL CLASS : Catecholamine FUNCTIONAL CLASS : Adrenergic direct acting beta1 agonist MECHANISM OF ACTION Dobutamine Stimulate the beta receptors in heart
- 13. Produce strong inotropic effect Alpha 1 agonist activity (vasoconstriction) Alpha 2 agonist affect (vasodilation) Increase myocardial contractility Increase cardiac output Decrease peripheral resistance Improves renal blood flow and urine output
- 14. ATROPINE GENERIC NAME : Atropine sulfate TRADE NAME : Atropine , Atropaza CHEMICAL CLASS : Belladonna alkaloid FUNCTIONAL CLASS : Anti muscarinic ,Anti cholinergic, Anti dysrrhythmic MACHANISM OF ACTION Atropine Muscarinic receptor of Ach blocks
- 15. Reduce muscarinic response of Ach in Smooth muscle Exocrin e gland Cardiac muscle Muscle relaxation Decrease secretion Decrease dysrhythmias leads to leads toleads to leads to
- 16. HYDROCORTISONE GENERIC NAME : Hydrocortisone Sodium Succinate TRADE NAME : Effcorlin, solu - cortef FUNCTIONAL CLASS : Corticosteroid CHEMICAL CLASS : Short – acting glucocorticoid MACHANISM OF ACTION Hydrocortisone Migration of polymorphonuclear leukocytes suppresses
- 17. Fibroblasts , and lysosomal stabilization Suppression of inflammation Leads to
- 18. MORPHINE GENRIC NAME : Morphine sulfate TRADE NAME : Astramorph PF , Avinza , Depo Dur CHEMICAL CLASS : Alkaloid FUNCTIONAL CLASS : Opioid analgesic MECHANISM OF ACTION Depresses pain impulse transmission at the spinal cord level by interacting with opioid receptors.