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compression and compaction.pptx
1.
2. CONTENTS:
1. PHYSICS OF TABLET COMPRESSION
2. COMPRESSION
3. CONSOLIDATION
4. EFFECT OF FRICTION
5. DISTRIBUTION OF FORCES
6. COMPACTION PROFILE
7. SOLUBILITY
3. COMPRESSION AND COMPACTION
COMPRESSION:
Compression means reduction of bulk volume of material as a
result of the removal of gaseous phase(air) by applied
pressure.
COMPACTION:
Compaction of the powder is the term is used to describe the
situation in which the materials are subjected to some level of
mechanical force.
COMPACTION =Compression + Consolidation of two phases
(solid-gas) on application of force.
4. 1. PHYSICS OF TABLET COMPRESSION
Tablet compression physics includes:
•Transmission of forces during compression
•Distribution of forces in tablets
•The effect of applied pressure on the relative volume of the
powder Interparticulate adhesion and cohesion forces
•Tablet compression energies
•Mechanical strength of tablets
•Detailed description of the tools used in these studies and
working methods.
5. STEPS INVOLVED IN THE COMPRESSION OF TABLET:
1. Transitional repacking or particle rearrangement
2. Deformation
3. Fragmentation
4. Bonding (here removal of process)
5. Deformation of solid body
6. Ejection
PROCESS OF TABLET COMPRESSION:
1.transitional repacking or particle rearrangement
It can be used for stress applied transformation of removal of
stress
