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Pathophysiology of malaria
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It is a disaccharide composed of the monosaccharides glucose come from blood and galactose ( ??) synthesized in golgi apperatus in mammary gland both linked by glycosidic link. It is only found in milk in its natural state , synthesized in mammary gland. It is found in form of opaque solution. Less sweet than sucrose. (5% sucrose=10% lactose) (double). Low soluble--- crystalization Fermentation Maillard reaction In order to digest lactose, your body digestive tract produces the enzyme lactase. Lactase is produced by the small intestine and secreted to break down lactose into its simpler forms of sugar—glucose and galactose. These simple sugars are easily absorbed into the bloodstream and used as energy.
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INTRODUCTION Aminoglycosides are a class of antibiotics used mainly in the treatment of aerobic gram-negative bacilli infections, although they are also effective against other bacteria including Staphylococci and Mycobacterium tuberculosis. They are often used in combination with other antibiotics. Streptomycin – 1944 Actinomycetes – Streptomyces griseus Bactericidal antibiotics which is interfere with protein synthesis Used to treat aerobic Gram –ve bacteria Exhibit ototoxicity and nephrotoxicity MECHANISM OF ACTION These drugs inhibit protein synthesis in the bacteria, there permeability is increased and cell contents leak out and death of cell occurs. These drugs leave bactericidal action. CLINICAL USES Gram –ve bacillary infection – Septicaemia, pelvic & abdominal sepsis Bacterial endocarditis – enterococcal, streptococcal or staphylococcal infection of heart valves Pneumonias, Tuberculosis Tularemia Plague, Brucellosis Topical – Neomycin, Framycetin:- Infections of conjunctiva or external ear and also used it before surgery. COMMON INDICATIONS OF AMINOGLYCOSIDES Gram negative bacillary infections particularly septicemia, meningitis, UTI’s renal, pelvic and abdominal sepsis. Bacterial endocarditis: usually gentamicin is preferred as a part of regimen. Other infections such as tuberculosis, plague, brucellosis etc. Topical uses: neomycin, framycetin and sisomicin are used for various topical infections. NURSING IMPLICATIONS The renal function should be regularly monitored. Patients should be regularly enquired about any side effects. Patients should be warned for not driving or operating the machinery. Patient should be advised to take plenty of water during the course. Monitor the sign and symptoms of hearing loss.
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It is a disaccharide composed of the monosaccharides glucose come from blood and galactose ( ??) synthesized in golgi apperatus in mammary gland both linked by glycosidic link. It is only found in milk in its natural state , synthesized in mammary gland. It is found in form of opaque solution. Less sweet than sucrose. (5% sucrose=10% lactose) (double). Low soluble--- crystalization Fermentation Maillard reaction In order to digest lactose, your body digestive tract produces the enzyme lactase. Lactase is produced by the small intestine and secreted to break down lactose into its simpler forms of sugar—glucose and galactose. These simple sugars are easily absorbed into the bloodstream and used as energy.
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