Dry Spot Blood (DBS) collection and testing has traditionally been characterized similarly to point of care testing (POCT) modalities. Although venipuncture remains the gold standard for phlebotomy, the ADx100 card collection media allows Bayshore Clinical Labs (a CLIA certified lab) to run any serum test and a hemoglobin a1C on the same testing platforms found at the local hospital or commercial laboratories

1. Comparison of Blood Collection and Testing Models
Venipuncture
Accuracy and
testing platform
Most accurate collection method
Reliable collection method for validating
results
Testing performed at CLIA certified
laboratory
Available Tests
Comprehensive menu of clinical chemistry
tests available: lipid panels, glucose,
cotinine, PSA, HbA1c, thyroid, TSH,
hsCRP, homocystiene and many more
5 minutes to perform the draw
98.2% success rate in obtaining the
required tubes in two attempts or less
~5% will need two draw attempts
~2% will not be able to provide a specimen
Trained certified phlebotomist
Supplies: tubes that expire, tourniquets,
alcohol preps, band aids, gauze, needles,
needle holders
Equipment: phlebotomy chair, centrifuges
Staff place collection tube in a rack for 1530 minutes to clot
Staff label transfer tubes and pour off
specimens accordingly
Risk of poor results due to specimen
degradation and hemolysis
Tourniquet technique can increase
cholesterol concentrations 10-15%
Hot and cold temperature exposure can
alter or negate test results.
Time to Perform
Draw
* summithealth.com
Requirements
Specimen
Preparation and
Handling
BayshoreClinical Laboratories
ADx100 Finger Stick
Finger Stick
Most accurate collection method
Reliable collection method for validating
results
Testing performed at CLIA certified
laboratory using same methodologies and
equipment as the local hospital
Comprehensive menu of clinical chemistry
tests available: lipid panels, glucose,
cotinine, PSA, HbA1c, thyroid, TSH,
hsCRP, homocystiene and many more
1.5 minutes to perform draw
99% success rate in obtaining required 4
blood drops
Good for baseline data
Accuracy is not the gold standard for
collection and testing
FDA approved POCT device provides
a “comparable” results and requires
calibration
Mostly limited to lipid panels and
glucose
Same technician conducting biometrics
Supplies, ADx100 card that has a five year
shelf life, alcohol preps, band aids, gauze,
spring activated lancet
No special equipment required
Air dry for sixty minutes and place into
protective pouch
Same technician conducting biometrics
Supplies, alcohol preps, band aids,
gauze, spring activated lancet
No special equipment required
1.5 minutes to perform draw
99% success rate in obtaining required
4 blood drops
Capillary tube is placed into point of
care device.

2. Inherent Patient
Risks
Patient
Compliance
Delivery of
Results
Patient and
Wellness
Management
Patient
Outcomes
Regulatory
Restriction
Excessive bleeding for patients with
coagulation issues on blood thinners or
clotting factors
Bruising or large hematoma
Syncope, fainting or dizziness
Nerve injury if basilica vein is chosen
Arterial nicks, Cellulitis, Phlebitis
Infection risk
Risk of patient adherence and compliance
Medically invasive
Anxiety and needle phobia
Longer wait time
Testing results completed at within 3-5
business days from receipt at the lab
Momentary pain or discomfort
Exposure site may be sore to the touch for
a short period of time
Minute hematoma
Infection risk
Limited risk of patient adherence and
compliance
Momentary pain or discomfort
Exposure site may be sore to the touch
for a short period of time
Minute hematoma
Infection risk
Limited risk of patient adherence and
compliance
Minimally invasive
No needle, limited anxiety
Shorter wait time
Testing results completed at within 3-5
business days from receipt at the lab
Minimally invasive
No needle, limited anxiety
Shorter wait time
Immediate results
Can be a teachable moment
Test accuracy acceptable to patient’s
Wellness coach, HCP, ACO, Medical
home, Quality management program, etc.
Suitable to incorporate into a reliable
action plan
Detailed data accuracy using approved
and accepted diagnostics increases the
effectiveness of intervention
State restrictions in California and
Maryland prevent venous blood draws for
screenings.
Most states require an order from a
licensed physician for all moderate and
highly complex laboratory testing
Test accuracy acceptable to patient’s
Wellness coach, HCP, ACO, Medical home,
Quality management program, etc.
Suitable to incorporate into a reliable action
plan
Detailed data accuracy using approved and
accepted diagnostics increases the
effectiveness of intervention
Most states require an order from a licensed
physician for all moderate and highly
complex laboratory testing
Creates initial awareness
Difficult to assess true risk
Not adopted or reliable enough for
medical professionals to develop a
reliable action plan
Creates awareness
Patient would still need to follow up
with their HCP for venipuncture
Most states require an order from a
licensed physician for all moderate and
highly complex laboratory testing