This document discusses various veterinary drug delivery systems including tablets, boluses, and feed additives. Tablets are less commonly used for animals than humans because animals may chew and spit them out. A bolus is a large compressed tablet, ranging from 3-16g, commonly used to provide higher dosages to larger animals. Feed additives can deliver drugs through an animal's food or water and come in medicated articles, medicated feed, or compressed blocks. Drinking water medications are either dry powders mixed into liquid or concentrated solutions added directly to water.

1. VETERINARY DRUG
DELIVERY SYSTEM
Presented by:
Karthik swamy B.M
M pharm 2nd sem
(pharmaceutics)
Under the guidance of:
PNVN Murthy SIR
V.L COLLEG OF PHARMCY
RAICHUR

2. CONTENTS
• INTRODUCTION
• TABLETS
• BOLUSES
• FEED ADDITIVES

3. INTRODUCTION
Veterinary dosage forms are drug prepartions
desgined for used in or topical application to one
or more species of domestic animal and/or other
species of veterinary interest.
“veterinary science is vital to study and follow
practies to protect animal production practies,
herd health and monitoring the spread of
disease”

4. Tablets and boluses
Solid dosage form like
compressed tablet is
most common in case
of humans. They are
less popular in animals
because
administration is
uncertain. Why the
administration is
uncertain….???

5. It is uncertain because one cannot be
sure the tablet is swallowed, spit out,
or drop from mouth after
administration.” Typically the tablet are
chewed by the animals and due to
undesirable taste of certain drug the
animals can spit out that tablet from
the mouth, this will result in loss of
dosage form. To avoid this the
flavoring agents, sweeteners pan be
added to the formulation.

6. Drugs are given on the basis of body
weight of the animal or body surface
area of animal.
Example-
1.15g of drug for each 150 kg body
weight
2.75g of drug for each 750 kg body
weight of cow or horses. A special
tablet called a “bolus” is commonly
used these large dosage. A bolus is
nothing more than a very large tablet ,

7. A special tablet called a “bolus” is
commonly used to provide larger
dosages.a bolous is nothing more than
A very large tablet which can range
from 3 to 16g or more.
Bolus formulation poses challegens
because of the high drug to excipent
ratio. Less room is left for
diluent,binders and other adjuvant.

8. Examples of bolus :
1. petazole-1500 and lamisole-300 is highly
effective and easily available in the
market and frequently prescribed against
all common round worms in GIT tract and
lung worms in poultry, cattle and sheep
2. 27g copper and 500mg selenium bolus
for cows and cattle
for long acting slow release of routine
supplementation.
Note: BOLUS are adminstered by an

9. Bolus gun

10. Feed Additives
Feed additive are preparations used in
veterinary medicine to deliver the API via
the water or food given to the animals.
They may be either solid or liquid and
sometimes also called as premix.

11. • Feed additives are mainly of
three types
• 1.Type A – medicated articles
• 2.Type B – medicated feed
• 3.Type C –medicated feed

12. • Type A – medicated articles Contain one or
more API Sold to licensed feed mill Product
are diluted with water or food and then
consumed.
• Type B – medicated feed Contain Type A
medicated articles With this it contain
nutrients (not less than 25% of total weight)
Product are diluted with water or food and
then consumed
• Type C – medicated feed This contains
compressed or molded blocks It also contains
the nutrients Product are diluted with water or

13. Drinking Water Medication
• Drinking Water Medications are
mainly categorized into two classes
• Dry Powder: Dry powder
reconstituted into liquid concentrate
and then mix into drinking water.
• Concentrated Solution: Dispensed
directly into drinking water in
medicinal proportion.

14. THANK YOU