The machinery industry is constantly changing, and the needs are doing the same. F+ Healthcare makes the best granulation equipment in this regard, and customers typically choose them because of their high quality. Before we can help you understand why F+ Healthcare is the best in the industry, it is crucial to understand who we are and what we do. Website- https://fve.international/granulation-equipment-manufacturer/

1. We've
got you
www.fve.international

2. We Are Committed
To Saving Lives.
Our purpose is
deeply rooted in the
belief that all lives
have equal value.
We are
accomplishing that by
building indigenous
manufacturing
capability and sharing
technology across
the globe
Thus ensuring ACCESS
to AFFORDABLE Life
Saving Drugs to
everyone
We have over 700 manufacturing installations in 53
countries.
Our Mission

3. Our consortium manufactures
safe
1997
2005
2012
2015
2016
Clean Room
Equipment &
Panels Containment
Systems (Isolators)
Granulation
Equipment
Capsule Filling
Machines
Water Generation
System
safe

4. OSD Formulation Process Flow

5. OSD Formulation Solutions
Sieving Granulation Drying Milling Blending Coating
1. Vibro Sifter
2. Turbo
Sifter
1. Rapid
Mixer
Granulator
2. Fluid Bed
Processor
1. Fluid Bed
Dryer
2. Vacuum
Tray Dryer
1. Multi Mill
2. Co Mill
1. Bin Blender
2. Octagonal
Blender
3. Double
Cone
Blender
4. V blender
1. Fluid Bed
Coater
2. Auto
Coater
Compres
sion
1. Tablet
Compres
sion
Machine
2. Capsule
filling
Machine

6. Oral Solid Dosage Process Equipment
(Granulation/Tablet line)
Features:
• cGMP Model
• Stainless Steel Construction
• Multi Deck Unit
• Works on gyro principle.
• Gyratory motion is obtained from specially designed gyro
motor which is fitted underneath the vibrating assembly.
• Vibrating assembly is isolated from the base by means of
specially designed springs.
Benefits:
• Less Power Consumption
• Easy to dismantle for Cleaning Screen
• Noiseless Operation
• Dust Free Arrangement
Vibro Sifter

7. Turbo Sifter
Features :
• Works through vacuum transfer system
• Carrier between FBD/FBP and Co-mill.
Benefits :
• Easy to assemble, operate & clean.
• Dust Free Operation
• Continuous Operation
• Cycle time reduction

8. Rapid Mixer Granulator
Features:
• Uniform Granules by Gentle Processing
• Uniform Mixing And Granulation
• Fully Automatic Operation Based On PLC Control
• Better Productivity And Lesser Mixing Time
• Less Handling, More Hygienic
• Bowl Shape Design To Have No Dead Spaces
Benefits:
• Unique “Impeller” design reduces the process
time while ensuring homogenous mixing and
formation of uniform granules
• Unique “Chopper” design ensures effective
reduction of oversized agglomerates,
distribution of binder fluids and ideal
compaction of granules.
• Unique “Discharge Port” design which ensures
emptying of the granules from the main bowl
in shortest time.

9. Features:
• cGMP Model
• Stainless Steel Construction
• Three Stage Filtration
• Precise Temperature Control
• PLC controlled Operation
• Explosion Relief Flap
• Minimum Change Overtime
• Intelligent process control & safety
interlocks
Benefits:
• Reduced change over time
• Specially designed for minimum drying
time.
• 100% Discharge
Fluid Bed Dryer

10. Features :
• PLC operations through recipe with 21 CFR compliance (as option).
• Three Stage Filtration i.e Pre-Filtration, Fine Filtration & HEPA Filtration.
• Spray gun in the machine designed for precise control of the coating process.
• Spray nozzle in “Single / Multi” nozzle configuration.
• Provision of peristaltic pump for delivering spray medium through the nozzle.
• Sampling port is provided to take out sample of the material during process for
testing without interrupting process cycle.
• Special design Temperature port is provided to monitor & maintain accurate
temperature through out process cycle.
• Fully sealed pneumatically controlled damper with “ 0 – 100%” positioning for
accurate air monitoring and control.
Benefits :
• Reduced investment and downtime.
• Reduced process time due to unique bowl design.
• Easy for cleaning through CIP.
• Easy and quick change over.
• Safe operation.
Fluid Bed Processor

11. Fluid Bed Coater
Features :
• PLC operations through recipe with 21 CFR compliance (as option).
• Three Stage Filtration i.e Pre-Filtration, Fine Filtration & HEPA Filtration.
• Spray gun in the machine designed for precise control of the coating process.
• Spray nozzle in “Single / Multi” nozzle configuration.
• Provision of peristaltic pump for delivering spray medium through the nozzle.
• Sampling port is provided to take out sample during process without interrupting the cycle.
• Temperature port is provided to monitor through out process cycle.
• Fully sealed pneumatically controlled damper with “ 0 – 100%” positioning .
Benefits :
• Reduced investment and downtime.
• Reduced process time due to unique bowl design.
• Easy for cleaning through CIP.
• Easy and quick change over.
• Safe operation.
TANGENTIAL
WURSTER

12. Features :
• VTS applied to carry the dried material from
FBP bowl to co-mill, through Vertex flow
pattern by means of rotating impeller,
where the product travels by continuous
centrifugal acceleration.
• 21 CFR Part 11 compliance.
• PLC operation through recipe as set by the
user.
Benefits:
• Accurate Speed control.
• Continuous process.
• Easy for cleaning.
• Less change over time.
Dry Co Mill with VTS

13. .
Features :
• Portable machine on castor wheels.
• Built in Variable Frequency Drive for multiple speeds.
• Multiple combination of Screens / Speeds / Number of Blades available.
• Direction of the Blade rotation can be changed using a Reversing switch for
Hammer or Knife operation.
Benefits :
• Specially designed for high speed Granulating, Pulverizing.
• Utilizes the principle of variable force swing hammer blades having both knife and
impact edges rotating with a selected screen to control particle size reduction.
• Streamlined flow path of material in vertical rotor machine.
Multi Mill

14. Working Principle :
F+ brings you various blending technologies to help you choose blenders from Laboratory to Production
capacities.
 DoubleConeBlenders
 OctagonalBlenders
 ContaBlender
 V-Blender
Blending Solutions

15. Bin blenders are the most widely used blenders owing to the
flexibility it offers with different capacities, closed loop material
transfer and better Mixing Efficiency. It also offers improved
material handling both upstream and downstream.
Features:
• PLC operations through recipe as set by the user.
• Tumbling.
• Rotation in a diagonally eccentric plane.
Benefits :
• Operator friendly
• 360o Rotation
• Easy to install, dismantle & clean.
Bin Blender

16. Octagonal Blender
Features:
• PLC operations through recipe as set by the user.
• 21 CFR Part 11 compliance.
• Material handling through Bin charging or a Vacuum charging system.
• Pneumatically actuated valves for dust free transfers
Benefits :
• Process large volume of material.
• Low Power Consumption.
• Bin charging system ensures Dust free closed system for Charging and
Discharging of Product

17. Features :
• Suitable for dry blending of free flowing solids.
• Materials being blended are constantly being intermixed as the Double Cone rotates.
• Depending on the characteristic of the product, paddle type baffles can be provided on
the shaft for better mixing, uniform blending and de-agglomeration
Benefits :
• Better mixing and Easy discharge
• Specially designed Cone which protects the gear box and motor from over loading.
Double Cone Blender

18. Features :
• Specially designed shape of the blender body results in a near complete
discharge of product material.
• Provision of Internal attachments like lump breakers possible.
• VFD for variable speed.
Benefits :
• Simple design requiring minimum maintenance.
• Quick loading / unloading.
• Easy to clean.
• The Bin charging system can also be incorporated in it which provides
dust free environment for charging and discharging.
V-Blender

19. Tablet Compression Machine
FVE II SE
FVE NX4
• Double sided rotary tablet press
• 10 ton main compression
• Turret with HELICAL RING AND PINION DRIVE with WORM REDUCTION
GEAR BOX
• Two piece turret with ELNP coating
• Manual side control for weight and thickness adjustment
• Two paddle force feeding system
• PLC control with TOUCH SCREEN HMI ALONGWITH PRINTING FACILITY
• Auto lubrication system and drip feed lubrication for punches Manual
Hydraulic Pump
• Double sided rotary tablet press
• 10 ton main compression and 10 ton pre compression
• Turret with Interchangeable Facility Two piece turret with ELNP coating
• Motorized weight and thickness control adjustment
• Three paddle force feeding system
• Powder level sensor
• PLC control with TOUCH SCREEN IPPC ALONGWITH PRINTING FACILITY
• Auto lubrication system and drip feed lubrication for punches
• Auto weight control (AWC) & single tablet rejection(AFR)
• ACVFD for main and force feeder motor

20. Tablet Compression Machine
EFSP (For Effervescent Tablets)
FVE Minitabs
• Single sided rotary tablet press
• 10 ton main compression
• Turret with WORM AND WORM RING DRIVESYSTEM
• Two piece turret with ELNP coating
• Manual control for weight and thickness adjustment inside cabinet
• Gravity feed frame
• Machine with VARIABLE PULLEY FOR TURRETSPEED CHANGE
• Double layer rotary tablet press
• 10ton first layer pre compression and 10 ton final tablet main
compression
• Turret with CENTRE DRIVE
• Two piece turret with ELNP coating
• Manual side control for weight and thickness of 1stand 2nd laver
• Two paddle force feeding system and gravity feed frame
• Single Side Machine Available with 4 ton Pre Compression & 10 ton main
Compression

21. Tablet Compression Machine
FVE EFSP II
• Single sided rotary tablet press
• 16 ton main compression
• Turret with HELICAL WORM AND WORM RINGDRIVE SYSTEM WITH WORM GEAR BOX
• Two piece turret with ELNP coating
• Manual side control for weight and thickness adjustment
• Gravity feed frame
• Machine with INTERCHANGEABLE FIXEDPULLEY FOR TURRET SPEED CHANGE
• Machine operation through control panel with pushbuttons and rotary potentiometer
• Manual hand pump lubrication system and drip feed lubrication for punches
• Manual hydraulic pump

22. TABLETING PUNCHES
single tip punch
Multi tip punches
Multi design
Dies

23. Auto Coater
Features:
• Stainless Steel Construction
• Automated process to maintain uniformity of coating.
• Precise Temperature Control
• PLC controlled Operation
• Minimum Change Overtime
• Intelligent process control & safety interlocks
• Pan cabinet is absolutely air tight and ensures no
pollution in production environment
Benefits :
• Minimum Operator Intervention.
• Quick Changeover.
• Easy to clean.
• Safety

24. Material Handling Equipment
Lifting and
Positioning Device
Multi-mill
Lifting and Tilting
Device
Conta Blender
Intermediate Bulk
Container

25. Material Handling Equipment
Features :
• Hydraulic operated lifting arm.
• Closed column construction with floor & ceiling fastening.
• Adjustable mount stop.
• Flameproof construction – Optional.
Benefits :
• Ease of control.
• Automatic hydraulic control as position control.
• Good balancing of attachments.
• 360 degree rotation of mast column.
Lifting and Positioning Device

26. Features :
• All contact parts AISI 316 & non contact parts AISI 304.
• Pneumatically operated ON/ OFF valve at bottom.
• Flameproof construction - optional
Benefits :
• Unloaded material with inline process with cone mill, granulator and
IBC for dust free process.
• Fully automatic system, with hydraulic lifting and tilting arrangement
for quick and easy handling.
• Less Operation time.
Material Handling Equipment
Tipper

27. Closed Loop Granulation
Sifting Granulation Drying Milling Blending
Wealsooffer Closedloop wall
mount Units for Granulation for
labswith space constraints.

28. Complete Capsule Filling Line
R&D Model Complete Production Line
Combination : Powder + Pellet + Tablet.
Micro tablets.
Capsule in Capsule.
Liquid in Capsule.
Softgel in Capsule.

29. R & D model for Capsule filling
Features
• Maximum output 1500 to 3000 capsules / hour
• Suitable for R&D Lab, Process Development Lab, Small
size production, trial / batch production
• Capable of filling powder, tablets, micro-tablets, pellets
and liquid under any conditions
• Auto rejection of capsules
• Quick Changeover
• No special tools required for changeover
• Machine manufactured as per cGMP norms
• Inbuilt vacuum pump for capsule separation
Optional Features
• Tablet attachment with NFD (Non Filling Detection)
• Liquid Filling Attachment
• Extra change part for capsule size
• Tablet filling attachment
• Partial filling attachment
• Dosing Disc
• IQ, 0Q, DQ documentation provided on requirement

30. Types of Capsule Filling machines
Manual capsule filling
Capacity
7500 capsules/hr
Semi-Automatic
Capsule filling
machine 20,000-
40,000 capsules/hr
Fully automatic
Capsule filling
machine 25,000 –
200,000 capsules /hr

31. Accessories
Metal
detector
Capsule Sorter
Elevator
Sample
Checkweigher
Capsule
Polisher

32. Automatic Capsule
Loader - Vertical /
Horizontal
Empty Capsule
Sorter
Capsule De-
Duster
Filled & Mini
Capsule Sorter

33. • Combiningour engineeringexpertise in Containment and GranulationFabtechBringsyouContainedGranulation for
Manufacturing of Oncology, Cytotoxic drugs,Hormonesand other suchcriticalformulations.
• Offers fromMaterialloadingtotabletcoating/Capsulefilling line meets OEL5.
• Below imagerepresentsIsolatorforOSDwithPLCwhichoperatesthroughautomation.
OSD Isolator

34. Containment Process
Pass Box Sifting Granulation Drying Milling & Blending Pass Box Compression Coating Discharge
●Isolated process ● AHU ● CIP ● PLC ● 21 CFR compliance

35. A Vast 10,000 Sq. Ft Manufacturing Unit

36. Manufacturing unit for Oral Solid Dosage
Process Equipment

37. Manufacturing unit for Capsule production
line

38. Our Global Landscape
50+
Countriesand
ProductLines
700+
Installations
Acquired The Trust, Support, And
Assurance Of Our Clients Across The
Globe

39. Clients Snapshot

40. Compliance, Certifications &Governance

41. You can reach usdigitally
www.fve.international

42. We’ve got you…
Thank you