It presents the history of the Earth through geologic time. It discusses the earth's structure, composition, and processes. Issues, concerns, and problems pertaining to natural hazards are also included. It also deals with the basic principles and processes in the study of biology.

1. GENERAL BIOLOGY
LESSON 1 LEARNING ACTIVITY SHEET
Activity 1: Create a timeline consisting of people and event who worked for the
development of the cell theory. Use the template below in completing your timeline.

2. GENERAL BIOLOGY
LESSON 1 LEARNING ACTIVITY SHEET
Guide Questions:
1. Who are the major contributors of the cell theory?
Theodor Schwann, Matthias Jakob Schleiden, and Rudolf Virchow
2. In a 1665 publication called Micrographia Robert Hooke coined the term “cell” for the
box like structure, he observed. What is the historical importance of his observation?
Hooke's discovery led to the understanding of cells as the smallest units of life, the
foundation of cell theory. It also helps other scientists in microscopoe constuction,
staining techniques, and lenses to see some other components inside of a cell.
Activity 2: The Meaning of Cell Theory
POSTULATES OF CELL THEORY SELF EXPLANATION
All living things are composed of one or
more cells
All living organisms are made up of one or
more cells, which are considered the
fundamental units of life because cells
provide structure for the body, take in
nutrients from food, and carry out
important functions.
Cell is the basic unit of life All the functions taking place inside the
body of organisms are performed by cells.
All new cells arise from existing cell This means that cells don't just appear out
of thin air. New cells are always made
from current cells.
Energy flow (metabolism and
biochemistry) occurs within cells
Energy flow occurs within cells. Hereditary
information (DNA) is passed on from cell
to cell. All cells have the same basic
chemical composition. All living organisms
in the kingdoms of life are composed of
and depend on cells to function normally.
Cells carry genetic material (DNA) passed
to daughter cell during cell division
The DNA will replicate in the parent cell
which then will have the chromatics split
to create a new cell (daughter cell)
containing the exact same DNA.
All cells are essentially the same in
chemical composition
All living cells arise from pre-existing cells
by division, energy flow (metabolism and
biochemistry) occurs within cells, cells
contain hereditary information (DNA)
which is passed from cell to cell during cell
division, all cells are basically the same in
chemical composition in organisms of
similar species.
Guide Questions:
1. How does Antoine Van Leuwenhoek contribute to the development of cell theory?
Leunwenhoek’ work was very important to debunking the theory of spontaneous
generation. Due to his observation we understand today that cells come from other cells.
He was the first person to examine many cells, including red blood cells. He was also the
first person to see the nucleus of these blood cells. Before him, the notion of cells as the
building blocks of living things was not widely accepted. We are also more knowledgeable
now of the world of microbiology and how these tiny organism work to sustain the circle
of life.

3. GENERAL BIOLOGY
LESSON 1 LEARNING ACTIVITY SHEET
2. If all cells only arise from pre-existing cells then where do first cell came from?
The first cell is thought to have arisen by the enclosure of self-replicating RNA and
associated molecules in a membrane composed of phospholipids.
Reflection:
3. What are the three concepts I learned from this Lesson (Cell Theory)
1) All living organisms are composed of one or more cells.
2) The cell is the basic unit of structure and organization in organisms.
3) Cells arise from pre-existing cells.
Activity 3: Cell Structure and their Function
CELL STRUCTURES FUNCTIONS
1. Nucleolus Assemble and produce ribosome
components within the cell. Besides that,
nucleolus mainly acts as a suspension
medium for cell-organelles in the nucleus
of the cell.
2. Nucleus Cell organelle that houses DNA and directs
synthesis of ribosomes and proteins
3. Ribosomes Protein synthesis
4. Vesicle Storage and transport; digestive function
in plant cells
5. Rough endoplasmic reticulum Manufactures membranes and secretory
proteins
6. Golgi apparatus Modifies, sorts, tags, packages and
distributes lipids and proteins
7. Cytoskeleton Maintains cells’ shape, secure organelles
on specific positions, allows cytoplasm and
vesicles to move within the cell, and
enables unicellular organisms to move
independently
8. Smooth endoplasmic reticulum Serves as a transitional area for vesicles
that transport ER products to various
destinations
9. Mitochondria ATP production or cellular respiration
10. Vacuoles Vacuoles are responsible for a wide variety
of important functions in a cell including
nutrient storage, detoxification, and waste
exportation.
11. Cytosal The cytosol has no single function and is
instead the site of multiple cell processes.
12. . Lysosome Digestion of macromolecules; recycling or
worn out organelles
13. Centrosome Unspecified role in cell division in animal
cells; organizing center of microtubules in
animal cells
14. Cell Membrane Separates cell from external environment;
controls passage of organic molecules,
ions, water, oxygen and wastes into and
out of the cell.

4. GENERAL BIOLOGY
LESSON 1 LEARNING ACTIVITY SHEET
Guide Questions:
1. Is the cell in the picture that of a plant or an animal?
A animal cell
2. Give three reasons for your answer?
1) There is no chloroplast.
2) The shape is circle (irregular).
3) Do not contain plastids
Activity 4: Comparing Plant and Animal Cell
Guide Questions:
1. Which cell parts are present only in plant cell?
Chloroplast and cell wall
2. Which cell parts are present only in animal cell?
Centrioles
3. Which cell parts are found in both cells?
Nucleus, Mitochondria, Cytoplasm, Golgi apparatus, Endoplasmatic reticulum, Ribosomes
Activity 5: Cell Analogy
Nucleus City Hall
Mitochondria Hydraulic dam
Cell Light City
Ribosomes Small stores
Protein Widget
Golgi Apparatus Postal Office

5. GENERAL BIOLOGY
LESSON 1 LEARNING ACTIVITY SHEET
Nucleolus Construction Engineer’s Union
Lysosomes Scrap yards
Cell Membrane Fence
Vesicles Special Carts
Reflection:
What are the three concepts I learned from this topic (Cellular Structure)
1) A cell consists of three parts: the cell membrane, the nucleus, and, between
the two, the cytoplasm.
2) Plant cells have cell walls and chloroplasts.
3) Eukaryotic cells share many similarities.
Activity 6: Reflective Reading and Writing
Douglas Malloch's poem Be the Finest of Whatever You Are repeatedly reminds us
to be the best of whatever we can be. We must never be ashamed of who we are, because
no job is too small or too big. Every work in this world is equally important to the people.
People are sometimes discriminated against because of their jobs, thus your success will
be determined solely by how you do your job. It, too, has different sections and functions,
just like a cell. Every part, no matter how tiny or large, is important.