Please fill in all the blanks. 2) T cells have (TCRs), which have an antigen- binding site for a specific epitope. 3) T cells mature under the influence of signals from the and they attack cells that harbor endogenous pathogens during -mediated immune responses. 4) In cell-mediated immunity, - also called CD8 positive (CD8+ cells) because they have membrane protein CD8-act against infected or abnormal body cells, including virus-infected cells, bacteria-infected cells, some fungus- or protozoan-infected cells, some cancer cells, and foreign cells that enter the body as a result of organ transplantation. 5) Two types of - Th1 and Th2-are characterized by a membrane protein, CD4, so they are CD4+ and direct cell-mediated and antibody immune responses, respectively. B Lymphocytes (B Cells) and Antibodies 1. , which in the red bone marrow, make immunoglobulins (Ig) of two types(BCRs) and 2. Immunoglobulins are complementary to epitopes and consist of two identical shorter chains and two identical longer chains joined via bonds to form Y shaped molecules. 3. are inserted into the cytoplasmic membranes of B cells via transmembrane polypeptides. 4. The arms of each heavy and light chain vary in amino acid sequence, and thus each is called a region. 5. The two variable regions form -binding sites. 6. Exact binding between an antigen-binding site and an epitope accounts for the of an antibody immune response. 7. Because an antigen typically has numerous , many different BCRs will recognize any particular antigen's epitopes, but each BCR recognizes only epitope. 8. When an antigenic epitope stimulates a specific B cell, the B cell begins reproducing. a. The daughter B lymphocytes are now called cells, secrete and no longer display 9. Antibodies: a. similar to BCRs in shape but are and lack most of the transmembrane portion of BCRs. b. Antibodies carry the same for an epitope as the BCR of the activated B cell. c. The arms, or (fragment, antigen-binding), of the antibody contain the antigen-binding sites. d. The antibody stem is called the (fragment, crystallizable). e. There are five basic types of stems, and these form the five classes of antibodies: , and .

1. Please fill in all the blanks.
2) T cells have (TCRs), which have an antigen- binding site for a specific epitope. 3) T cells
mature under the influence of signals from the and they attack cells that harbor endogenous
pathogens during -mediated immune responses. 4) In cell-mediated immunity, - also called CD8
positive (CD8+ cells) because they have membrane protein CD8-act against infected or abnormal
body cells, including virus-infected cells, bacteria-infected cells, some fungus- or protozoan-
infected cells, some cancer cells, and foreign cells that enter the body as a result of organ
transplantation. 5) Two types of - Th1 and Th2-are characterized by a membrane protein, CD4,
so they are CD4+ and direct cell-mediated and antibody immune responses, respectively. B
Lymphocytes (B Cells) and Antibodies 1. , which in the red bone marrow, make
immunoglobulins (Ig) of two types(BCRs) and 2. Immunoglobulins are complementary to
epitopes and consist of two identical shorter chains and two identical longer chains joined via
bonds to form Y shaped molecules. 3. are inserted into the cytoplasmic membranes of B cells via
transmembrane polypeptides. 4. The arms of each heavy and light chain vary in amino acid
sequence, and thus each is called a region. 5. The two variable regions form -binding sites. 6.
Exact binding between an antigen-binding site and an epitope accounts for the of an antibody
immune response. 7. Because an antigen typically has numerous , many different BCRs will
recognize any particular antigen's epitopes, but each BCR recognizes only epitope. 8. When an
antigenic epitope stimulates a specific B cell, the B cell begins reproducing. a. The daughter B
lymphocytes are now called cells, secrete and no longer display 9. Antibodies: a. similar to BCRs
in shape but are and lack most of the transmembrane portion of BCRs. b. Antibodies carry the
same for an epitope as the BCR of the activated B cell. c. The arms, or (fragment, antigen-
binding), of the antibody contain the antigen-binding sites. d. The antibody stem is called the
(fragment, crystallizable). e. There are five basic types of stems, and these form the five classes
of antibodies: , and