The document discusses the Innovation Exchange and SBRI Healthcare programs which aim to accelerate the development and adoption of innovative healthcare solutions in England. It provides background on Karen Livingstone, the director of the programs. It then outlines key forces shaping global healthcare and describes the 15 Academic Health Science Networks that work locally and nationally to drive innovation adoption across England. The rest of the document details how the Innovation Exchange identifies healthcare needs and supports companies through funding competitions, needs assessments, and providing support to help ready solutions for adoption across the NHS. It provides examples of companies it has supported in areas like patient engagement, chronic condition management, and early disease detection.
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Karen Livingstone - ECO 17: Transforming care through digital health
1. The Innovation Exchange and SBRI Healthcare
Transforming Health and Social Care Services
4 December 2018
Eco 18
2. 2
• National Director NHS – leading £81m innovation programme
• Fellow of the Judge Business School, Cambridge
• Graduate of the Global Health Leadership, Yale University
• Formerly board member of 5 public and private boards
• Formerly Special advisor to Secretary of State for Health
• Politics graduate with 20+ years of national political
3. Forces shaping global healthcare
• Population pyramids are inverting
• Chronic disease will dwarf other needs
• Patient expectations are rising
• Emerging markets will be a large driver of growth across all
markets
• Financial pressures will require focus on productivity
• Health systems shifting to integrated care and outcomes
based payments
• Explosion of patient level healthcare data
• Innovation is rapidly evolving the life sciences towards
convergence
4. 15 Academic Health Science Networks (AHSNs)
across England.
• 15 Academic Health Science Networks, complete
coverage of England
• Five-year licence to drive innovation, adoption
and spread
• Working nationally to deliver major programmes
such as the Accelerated Access Review and the
Innovation Exchange
• Working locally to support transformation and
improvement, linking with STPs and other key
partners
www.ahsnnetwork.com
5. Evidence assessment frameworks & evaluation of evidence
Innovation support landscape
Proof of
concept Development Testing
Clinical
Trials Adoption 1
Regional
adoption
Wide spread
adoption
SBRI Healthcare
NIA Accelerator
National Institute for
Health Research
Innovation Technology
Payments
Clincal entrepeneurs
Digital accelerator
Med Tech
Accelerator
Venture funding
Innovate UK
Angel funding
Accelerated Access
Collaborative
The INNOVATION Exchange
6. Ideas into Practice
Accelerate solutions
• Define problems: 3-5 year
• Create solutions through
competitive process
• Invest in their co-development
• Develop solutions that bring
patient & economic success
Accelerate adoption
• Define problems: 1-3 year
• Support NHS to adopt ready to
use solutions
• Support innovators to navigate
& connect
• Broker solutions that bring
patient and economic value
The INNOVATION Exchange
7. Contract
Due diligence &
contracting. Fix and
agree milestones.
Interview Panel: 360 assessment
– investor style consideration of
tech, business and clinical
considerations
Clinical assessment: match to identified
need. Provenance of science/technology
approach. Team – engagement of clinical/
user voice
Tech assessment: competitive environment/ IP /
technology development / assessment of project plan &
deliverables
Workshop & briefings: specialist help from problem holders –
guidance to companies on NHS market access & reality of workplace
environment
Needs identification: policy context/service assessments / detailed workplace
considerations
AHSN support
• Access to key clinicians
• Access to patient groups
• Trial/pilot sites
• Roll out from one to many
SBRI team support
• Health Economic analysis &
market access understanding
• Support through ethics
approval & establishing clinical
trials
• Connection to UKTI, HMRA &
others
Approx
300/comp
Approx 130
apply
Approx 60
Approx 15
(12%)
SBRI funds
Phase 1 award: £100k – 6 months
Phase 2 award: up to £1m
9. Creation – case studies
Dovetail:
Working with blockchain
solutions to give patients full
control of their healthcare
records and deliver collaborative
exchange of data between
health services.
Increasing accountability and
mitigating risk and maximising
health outcomes for patients.
Brain Miner is developing
Diagnosis in Dementia (DIADEM),
an automated, extensible, and
personalised healthcare platform for
assisting the clinical diagnosis of
dementia. DIADEM using currently
available imaging data by delivering
a software infrastructure that can
automatically and intelligently
analyse MR imaging data and feed
the results to the end-user clinicians
in a visually intuitive fashion.
Owlstone Medical -
Ambition to save 100,000 lives &
$1.5bn in healthcare costs
Early detection of lung cancer is
first target.
Colorectal Cancer next target:.
Medium term: stratification of
asthma treatment.
Analysis of non-invasive
biomarkers in breath.
Company supported to connect
Clinical leads, patient voice &
backed for investors
10. From bench to bedside – case studies
uMotif/ADI/MyMHealth
iPLATO digital hub with a
population-wide, multi-channel
patient engagement platform
connected to consenting GP
practices. It allows regional
teams working in partnership
with GP surgeries to run
powerful, data driven, patient
engagement campaigns
across SMS.
365 response has a number of
cloud-based technology
solutions for transportation
companies, councils, facilities
management organisations and
community and social care
transport providers.
They offer a complete transport
and flow system, with auditable
compliance.
A range of companies with
patient engagement and
condition management tools.
ADI – pain management
uMotif – participation and
informed patients
My mHealth – chronic condition
management tools.
11. Ideas into Practice
Accelerate solutions
• Define problems: 3-5 year
• Create solutions through
competitive process
• Invest in their co-development
• Develop solutions that bring
patient & economic success
Accelerate adoption
• Define problems: 1-3 year
• Support NHS to adopt ready to
use solutions
• Support innovators to navigate
& connect
• Broker solutions that bring
patient and economic value
The INNOVATION Exchange
12. How the innovation exchange works
1. Innovator support and sign posting
A range of support for Innovators – SMEs, clinical entrepreneurs, digital, medtech, biotech.
Support to engage with the Innovation Exchange and across the NHS
6. Adoption and spread
Some products will be adopted in regionally supported
activity others in nationally led programmes
2. Needs Articulation
Patients, clinical, managerial voices drawn in to help define needs.
Needs will reflect the market opportunity as well as the efficiency expectations of the NHS.
3. Real world validation
Pathway testing of clinically validated innovations – to enable
workflow, training and system planning to be tested.
Economic and impact reviews will be shared across the AHSNs
1billion more people on the planet – 90% of whom will be in merging markets
Half a billion more people older than 50 and >320m people older than 80 by 2030
Chronic Diseases (those that are persistent/long lasting eg arthritis, asthma, COPD diabetes) will account for over 80% of (DALYs – disability adjusted life years)
By 2025 the global economy will almost double compared to today – led by Asia.
By 2023 emerging market pharma sales will account for 45% of the global total (up from 35% now)
NHS productivity shortfall likely to be £28bn by 2023
The Innovation Exchange is an AHSN coordinated approach to identify, select and support the adoption of innovations that improve our economy and patients lives.
The Innovation Exchange has four structured elements: needs articulation; innovator support & signposting; real world validation and spread adoption of supported innovations.
The Innovation Exchange will identify innovations for the Accelerated Access Collaborative and for local adoption.