oral pathology

1. Calcifying epithelial
odontogenic tumor
DONE BY
 TAQI HUSSAIN
 JASIM MOHAMMED
 HUSSAIN MAHDI

2. Reference
 Shafers textbook of oral pathology – 7th edition
 • Reichart P, Philipsen HP. Odontogenic tumours and
allied
 lesions.London: Quintessence Books, 2004.
 • Lucas’s pathology of tumor of the oral tissue - HA
Cawson
 • Text Book of oral and maxillofacial pathology –
Neville .
 • Odontogenic tumours: a short version.
 • Bouckaert MM, Raubenheimer EJ, Jacobs FJ.
Calcifying epithelial
 odontogenic tumor with intracranial extension: report
of a case and
 review of the literature. Oral Surg Oral Med Oral Pathol
Oral Radiol
 Endod 2000; 90: 656–62.
 https://en.wikipedia.org/wiki/Calcifying_epithelial_odontogenic_t
umor#See_also
 http://www.clinicalimagingscience.org/article.asp?issn=2156-
7514;year=2013;volume=3;issue=2;spage=11;epage=11;aulast=
Misra

3. Is A Rare, Aggressive, Benign
Odontogenic Tumor Of Epithelial
Origin Accounting For Only About
1% Of All Odontogenic Tumors.
First Recognized By Pindborg

4. epithelial element of the enamel
I'm the cause
hahahah

5. INTRAOSSEOUS TUMORS
(TUMORS WITHIN THE BONE)
ARE MORE LIKELY (94%)
VERSUS EXTRAOSSEUS
TUMORS (6%)
Type of it

6. Clinically
Why slight predilection for
females ?? Why!!

7. Ranging in age
from 20–60 years

8. INTRAOSSEOUS
PAINLESS MASS
SLOWLY GROWING
POST. MAND.

9. Extraosseus
Painless
Firm Gingival Mass
Antr.
Mucosa show ulceration
due to trauma
Headache

10. • A locally invasive
epithelial neoplasm
structure amyloid like
nature

11.  Epithelial cell
 sheets and nests of polyhedral
epithelial cells with an abundant
eosinophilic, granular cytoplasm
 Cellular outlines were distinct and
intercellular bridges were noted
 Considerable nuclear
polymorphism was a frequent
finding
 Extracellular amyloid-like substance
and calcified

12. Calcification deposit
 Are seen to be
associated with
amyloid deposit &
can be either
calcified amyloid or
collagen
 As the amyloid gets
calcified it looses it
congo red positivity

13. The calcification can be formed
as lamellae by fusion of small
calcific referred as
liesegang rings

14. Variations in
histo.
 Occurrence of amyloid
like
 Cementum ike like
 clear cells
 Langerhans cells
 Myoepithelial cell
Clear cell variant

15. Radiographic
On radiographs, it appears as
a radiolucency (dark area)
and is known for sometimes
having small Radiopacities
(white areas) within it
Usually associated with
impacted /unerupted

16. Radiographic
Large become
multilocular with
poor defined
border soap
bubble

17. Radiographic
Small unilocular associated wit
impacted teeth
The extraossuse type show ridge
erosion

18. Differential diagnosis
Ameloblastoma
When dentin & enamel present is
• Regional odontodysplasia
complete radiolucent
 Dentigerous cyst
 Odonto. Keratocyst
 Myxoma
Dentigerous cyst

19. Treatment
Surgical removal by enculation
Is more aggressive in maxilla
So is more dangerous

20. Treatment
 Some Times If Extensive
Replacement Of Bone By Plate
 Recurrence rate is 10% - 15%

21. Treatment
 Easy to enucleated
 Size 1-4 cm
 Grayish white or yellow
 When bisecting reveals calcified particles
 The tumor is solid or contain minute cystic
space