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TUBERCULOUS ARTHRITIS OF
RIGHT ELBOW JOINT
Dr. V. R. Raghul, M.S. 2nd Year PG, Department of Orthopaedics
Prof. Dr. Nalli R Yuvraj, HOD - Department of Orthopaedics
Dr. Pradeep E, Associate Professor
Dr. Arun K V, Associate Professor
Chettinad Hospital and Research Institute, Kelambakkam
INTRODUCTION
Incidence of TB elbow: 2-5% of
all skeletal locations.
The elbow joint is the most
frequently involved joint in
tubercular infections of the
upper limb.
Despite substantial progression
of the disease and ambiguous
symptoms, necessary evaluation
are not performed.
TB arthritis is often
misdiagnosed.
CASE REPORT
A 55-year-old male with complaints of pain over right elbow for
past 6 months.
Swelling and difficulty in movement for past 3 months.
H/o loss of weight. (5kgs lost in the past 6 months)
No other history of constitutional symptoms.
NO H/O cough with expectoration
L/E OF RIGHT ELBOW
5*3cm swelling present over
posteromedial aspect of elbow
extending into distal arm
Muscle wasting present over forearm,
biceps, triceps
Warmth present
Non tender
Firm in consistency
Mobile
Elbow ROM: FFD 60° to 100°; further
restricted and painful
Pre-op Images
RADIOGRAPHS
Right elbow shows arthritic changes:
AP view
Lateral view
MRI
MRI right elbow showed inflamed synovium and joint effusion,
RADIOGRAPH OF CHEST
PA view
Non homogenous opacities
seen in right upper zone and
lower zone and left upper zone
and mid zone.
INVESTIGATIONS
ESR and CRP elevated.
Mantoux positive (17mm)
Sputum for AFB was sent and
was positive
SURGERY
Excision biopsy of the
swelling was done
Sent for histopathology gene
xpert and microbiology
LJ media: shows typical
rough and tough buff-
colored colonies
AFB: Long slender,
beaded, less uniformly
stained and red
coloured acid-fast
acid-fast bacilli
MGIT Tube:
Mycobacterial
Growth Indicator
Tube from tissue bit
and pus was positive.
Rapid card test:
Card Test for
Mycobacterium
tuberculosis
yielded a
positive result
Histopathology Report: Features consistent with caseating granulomatous
inflammation.
DIAGNOSIS
Tuberculous Arthritis of right elbow joint
Patient was started on ATT
• FDC
• 4 HRZE for 2 months (Intensive phase)
followed by 4 HRE continuation phase,
patient is in the 5th month maintenance
phase
6 MONTHS FOLLOW UP
6 MONTHS FOLLOW UP
RADIOGRAPHS
AP view
Lateral view
DISCUSSION
Osteoarticular TB and AIDS have
grown increasingly widespread in
developing countries.
Increased HIV incidence due to factors like
immigration, alcoholism, chronic diseases,
homelessness, and limited healthcare access.
Osteoarticular tuberculosis affects
1%-3% of cases, with 2%-4% in
immuno-depressed individuals.
Osteoarticular TB primarily affects spinal,
upper limb joints, and elbows.
DISCUSSION
Tubercle bacilli spread from pulmonary lesions
cause musculoskeletal involvement.
Tuberculous arthritis causes chronic pain, edema,
and function loss, with slow diagnosis and poor
therapy outcomes.
50% of individuals have no radiological pulmonary
involvement, TB history possible.
Positive tuberculin skin test confirms diagnosis,
negative results don't rule out TB.
DISCUSSION
Early lesions may be missed due to non-specific radiological
findings; periarticular osteopenia may progress, leading to joint
narrowing.
Joint obliteration, fibrous ankylosis, osteoarticular tuberculosis,
osteoporosis, erosions, and progressive cartilage constriction
may develop without treatment.
MRI assesses soft-tissue masses, 99mTc bone scans detect
osteomyelitis early.
CT-guided percutaneous biopsy aids diagnosis, mycobacterial
culture confirms diagnosis, and biopsies are the best tool for early
treatment in osteoarticular TB.
DISCUSSION
Disability is determined by diagnosis and treatment period for
osteoarticular tuberculosis.
Osteoarticular tuberculosis treated with chemotherapy and non weight-
bearing joint exercises.
Osteoarticular tuberculosis treated with chemotherapy and joint
exercises.
Surgery may be necessary for biopsy and confirmation, and joint
arthrodesis or replacement may be considered.
CONCLUSION
In conclusion, immunocompromised and endemic individuals with
unexplained soft-tissue edema, swelling, and discomfort should be
investigated for osteoarticular tuberculosis.
Early diagnosis and therapy may improve function.
An enlarged elbow should be checked for pyogen
arthritis, gout, pigmented villonodular synovitis,
haemophilic arthropathy, rheumatoid arthritis, synovial
osteochondromatosis, and malignancies.
REFERENCES
1. Tangadulrat P, Suwannaphisit S (March 08, 2021) Tuberculosis Septic Arthritis of the Elbow: A
Case Report and Literature Review. Cureus 13(3): e13765. doi:10.7759/cureus.13765
2. Domingo, A., Nomdedeu, M., Tomás, X. et al. Elbow tuberculosis: an unusual location and
diagnostic problem. Arch Orthop Trauma Surg 125, 56–58 (2005).
3. Dhillon MS, Goel A, Prabhakar S, Aggarwal S, Bachhal V. Tuberculosis of the elbow: A
clinicoradiological analysis. Indian J Orthop. 2012 Mar;46(2):200-5.
THANK YOU

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TB in Elbow Joint.pptx

  • 1. TUBERCULOUS ARTHRITIS OF RIGHT ELBOW JOINT Dr. V. R. Raghul, M.S. 2nd Year PG, Department of Orthopaedics Prof. Dr. Nalli R Yuvraj, HOD - Department of Orthopaedics Dr. Pradeep E, Associate Professor Dr. Arun K V, Associate Professor Chettinad Hospital and Research Institute, Kelambakkam
  • 2. INTRODUCTION Incidence of TB elbow: 2-5% of all skeletal locations. The elbow joint is the most frequently involved joint in tubercular infections of the upper limb. Despite substantial progression of the disease and ambiguous symptoms, necessary evaluation are not performed. TB arthritis is often misdiagnosed.
  • 3. CASE REPORT A 55-year-old male with complaints of pain over right elbow for past 6 months. Swelling and difficulty in movement for past 3 months. H/o loss of weight. (5kgs lost in the past 6 months) No other history of constitutional symptoms. NO H/O cough with expectoration
  • 4. L/E OF RIGHT ELBOW 5*3cm swelling present over posteromedial aspect of elbow extending into distal arm Muscle wasting present over forearm, biceps, triceps Warmth present Non tender Firm in consistency Mobile Elbow ROM: FFD 60° to 100°; further restricted and painful Pre-op Images
  • 5. RADIOGRAPHS Right elbow shows arthritic changes: AP view Lateral view
  • 6. MRI MRI right elbow showed inflamed synovium and joint effusion,
  • 7. RADIOGRAPH OF CHEST PA view Non homogenous opacities seen in right upper zone and lower zone and left upper zone and mid zone.
  • 8. INVESTIGATIONS ESR and CRP elevated. Mantoux positive (17mm) Sputum for AFB was sent and was positive
  • 9. SURGERY Excision biopsy of the swelling was done Sent for histopathology gene xpert and microbiology
  • 10.
  • 11.
  • 12. LJ media: shows typical rough and tough buff- colored colonies AFB: Long slender, beaded, less uniformly stained and red coloured acid-fast acid-fast bacilli MGIT Tube: Mycobacterial Growth Indicator Tube from tissue bit and pus was positive. Rapid card test: Card Test for Mycobacterium tuberculosis yielded a positive result
  • 13. Histopathology Report: Features consistent with caseating granulomatous inflammation.
  • 14. DIAGNOSIS Tuberculous Arthritis of right elbow joint Patient was started on ATT • FDC • 4 HRZE for 2 months (Intensive phase) followed by 4 HRE continuation phase, patient is in the 5th month maintenance phase
  • 18. DISCUSSION Osteoarticular TB and AIDS have grown increasingly widespread in developing countries. Increased HIV incidence due to factors like immigration, alcoholism, chronic diseases, homelessness, and limited healthcare access. Osteoarticular tuberculosis affects 1%-3% of cases, with 2%-4% in immuno-depressed individuals. Osteoarticular TB primarily affects spinal, upper limb joints, and elbows.
  • 19. DISCUSSION Tubercle bacilli spread from pulmonary lesions cause musculoskeletal involvement. Tuberculous arthritis causes chronic pain, edema, and function loss, with slow diagnosis and poor therapy outcomes. 50% of individuals have no radiological pulmonary involvement, TB history possible. Positive tuberculin skin test confirms diagnosis, negative results don't rule out TB.
  • 20. DISCUSSION Early lesions may be missed due to non-specific radiological findings; periarticular osteopenia may progress, leading to joint narrowing. Joint obliteration, fibrous ankylosis, osteoarticular tuberculosis, osteoporosis, erosions, and progressive cartilage constriction may develop without treatment. MRI assesses soft-tissue masses, 99mTc bone scans detect osteomyelitis early. CT-guided percutaneous biopsy aids diagnosis, mycobacterial culture confirms diagnosis, and biopsies are the best tool for early treatment in osteoarticular TB.
  • 21. DISCUSSION Disability is determined by diagnosis and treatment period for osteoarticular tuberculosis. Osteoarticular tuberculosis treated with chemotherapy and non weight- bearing joint exercises. Osteoarticular tuberculosis treated with chemotherapy and joint exercises. Surgery may be necessary for biopsy and confirmation, and joint arthrodesis or replacement may be considered.
  • 22. CONCLUSION In conclusion, immunocompromised and endemic individuals with unexplained soft-tissue edema, swelling, and discomfort should be investigated for osteoarticular tuberculosis. Early diagnosis and therapy may improve function. An enlarged elbow should be checked for pyogen arthritis, gout, pigmented villonodular synovitis, haemophilic arthropathy, rheumatoid arthritis, synovial osteochondromatosis, and malignancies.
  • 23. REFERENCES 1. Tangadulrat P, Suwannaphisit S (March 08, 2021) Tuberculosis Septic Arthritis of the Elbow: A Case Report and Literature Review. Cureus 13(3): e13765. doi:10.7759/cureus.13765 2. Domingo, A., Nomdedeu, M., Tomás, X. et al. Elbow tuberculosis: an unusual location and diagnostic problem. Arch Orthop Trauma Surg 125, 56–58 (2005). 3. Dhillon MS, Goel A, Prabhakar S, Aggarwal S, Bachhal V. Tuberculosis of the elbow: A clinicoradiological analysis. Indian J Orthop. 2012 Mar;46(2):200-5.