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TUBERCULOSIS
Medicina Interna III
Integrantes: Gabriela Santos
Aylin Fong
Emely
DEFINICIÓN
Es una enfermedad infecto contagiosa, transmisible,
curable, usualmente crónica, de presentación clínica
variable, producidas por micobacterias del complejo
Micobacterium tuberculosis que puede causar
incapacidad de por vida o la muerte.
ETIOLOGIA  Las micobacterias pertenecen a la familia
Mycobacteriaceae y al orden Actinomycetales:
● MYCOBACTERIUM TUBERCULOSIS
● Es el mas frecuente en el hombre (95 a 99%)
● Su pared celular esta constituida por lípidos
ac. grasos α-alquilicos y βhidroxilicos.
● Se tiñe con ZN(carbolfucina) y con AR.
Micobacterium tuberculosis Características
• Bacilo aerobio fino, ácido-alcohol
resistente.
• No esporógeno.
• Mide de 0,5 por 3 μm.
por 3 μm.
EPIDEMIOLOGIA
• La OMS calcula que en 2016 ocurrieron
alrededor de 10.4 millones (intervalo, 8.8 a
12.2 millones) de nuevos casos de TB en
todo el mundo, 95% de los cuales ocurrió en
países en vías de desarrollo en el continente
asiático (6.5 millones), Africa (2.6 millones),
el Medio Oriente (0.77 millones) y
Latinoamérica (0.26 millones)
• Durante los últimos años se han reducido las
cifras de casos informados, y se ha iniciado
su reducción o estabilización en naciones
industrializadas.
DE LA EXPOSICIÓN A LA
INFECCIÓN
01
02
03
04
M. tuberculosis se transmite casi
siempre desde un paciente con TB
pulmonar contagiosa a otras
personas por medio de las gotitas
respiratorias que la tos, el estornudo
o la fonación convierten en un
aerosol.
Estas gotas diminutas se secan
pronto; las menores (<5 a 10 μm de
diámetro) pueden permanecer
suspendidas en el aire durante horas
y alcanzar las vías respiratorias
terminales al ser inhaladas.
Con cada golpe de tos se
pueden expulsar nada
menos que 3000 gotitas
contagiosas.
Uno de los factores más
importantes para la transmisión de
los bacilos tuberculosos es el
hacinamiento en espacios mal
ventilados, porque se intensifica el
contacto con el enfermo.
DE LA INFECCIÓN A LA
ENFERMEDAD
Cuando la infección se adquiere
en etapas avanzadas de la vida,
es mayor la probabilidad de que
el sistema inmunitario maduro
contenga la infección, al menos
en forma temporal.
La enfermedad clínica que se
desarrolla poco después
de la infección se clasifica
como tuberculosis primaria.
A B
F
E D
C
El riesgo de enfermar después
de infectarse depende ante todo
de factores endógenos.
Sin embargo, el bacilo inactivo puede
persistir por años antes de reactivarse y
producir tuberculosis secundaria
(o posprimaria)
El factor de riesgo más importante
es sin duda la infección simultánea
por VIH, que suprime la inmunidad
celular.
El riesgo de que una infección
latente por M. tuberculosis se
convierta en un proceso activo
depende directamente del grado
de
inmunodepresión del paciente.
Tuberculosis infographics
60 %
100 %
50 %
75 %
Mercury is the closest
planet from the sun
Mercury
1
Despite being red, Mars
is actually a cold place
Mars
2
Saturn is a gas giant and
has several rings
Saturn
3
Neptune is the farthest
planet from the Sun
Neptune
4
Tuberculosis infographics
Saturn Venus Mars
Mercury is the
smallest planet
Venus Venus is the second
planet from the Sun
Mars is full of iron oxide dust
and a cold place
Saturn is a gas giant and has
several rings
Mars Jupiter is the biggest
planet of them all
Neptune is the farthest
planet from the Sun
Mercury is the closest planet
to the Sun
Treatment for tuberculosis
Tuberculosis infographics
Mercury
Mercury is the
smallest planet
01
Venus
Venus is the second
planet from the Sun
02
Mars
Mars is actually a
very cold place
03
Jupiter
Jupiter is the
biggest planet
04
Venus
Venus has a
beautiful name
05
Neptune
Neptune is very far
from the Earth
06
Tuberculosis infographics
Jupiter
Jupiter is the
biggest planet of
them all
5%
Neptune
Neptune is the
farthest planet
from the Sun
15%
Mercury
Mercury is the
smallest planet of
them all
30%
Saturn
Saturn is a gas
giant and has
several rings
50%
Venus
Venus is the
second planet from
the Sun
85%
The symptoms of tuberculosis
1 2 3
Tuberculosis infographics
Mercury
Mercury is the closest
planet to the Sun and the
smallest of them all
Mars
Despite being red, Mars is
actually a cold place. It’s
full of iron oxide dust
Jupiter
Jupiter is a gas giant and
the biggest planet in the
Solar System
Tuberculosis infographics
3
1 5
4
2
Mercury
Mercury is the
smallest planet
Venus
Venus is the second
planet from the Sun
Mars
Mars is actually a very
cold place
Jupiter
Jupiter is the biggest
planet of them all
Saturn
Saturn is made of
hydrogen and helium
Several tests are used to diagnose tuberculosis
Tuberculosis infographics
Mercury is the closest
planet to the Sun
Mercury
01
Venus
Venus is the second
planet from the Sun
02
Jupiter
Jupiter is the biggest
planet of them all
03
Neptune
Neptune is the farthest
planet from the Sun
04
Saturn
Saturn is a gas giant and
has several rings
05 3
2
1
4 5
Tuberculosis infographics
50%
Saturn
Saturn is a gas giant and
has several rings
60%
Jupiter
Jupiter is the biggest planet
of them all
70%
Neptune
Neptune is the farthest
planet from the Sun
40%
Earth
Earth is the third planet
from the Sun
Tuberculosis infographics
Mercury is the closest planet to the
Sun and the smallest one. The
planet’s name has nothing to do
with the liquid metal
60%
Mercury
Venus has a beautiful name and is
the second planet. It’s terribly hot,
even hotter than Mercury. It’s the
second-brightest natural object
85%
Venus
Tuberculosis infographics
55%
01
Venus has a beautiful
name and is the
second planet from the
Sun. It’s terribly hot
Venus
90%
02
Mercury is the closest
planet to the Sun and
the smallest one in the
Solar System
Mercury
Who is the most susceptible to tuberculosis?
Tuberculosis infographics
Saturn
Saturn is a gas
giant and has
several rings
01
Venus
Venus is the
second planet
from the Sun
02
Neptune
Neptune is the
farthest planet
from the Sun
03
Earth
Earth is the
third planet
from the Sun
04
What causes tuberculosis?
Tuberculosis infographics
Mars
Despite being red, Mars
is a cold place. It’s full
of iron oxide dust
Mercury
Mercury is the closest
planet to the Sun and
the smallest of them all
Venus
Venus has a beautiful
name and is the second
planet from the Sun
Jupiter
Jupiter is a gas giant
and the biggest planet
in the Solar System
Tuberculosis infographics
Mars
Mars is actually a
very cold place
Venus
Venus has a very
beautiful name
Saturn
It's a gas giant with
several rings
Mercury
It’s the closest planet
to the Sun
Follow the link in the graph to modify its data and then paste the new one here. For more info, click here
Mercury
It is the smallest
planet of them all
90%
80%
20%
40%
65%
Countries with high TB rates
Tuberculosis infographics
Jupiter Saturn Neptune Mercury Venus
● Jupiter is the
biggest planet of
them all
● It was named
after the Roman
god of the skies
and lightning
● Saturn is a gas
giant and has
several rings
● It's composed
mostly of
hydrogen
and helium
● Neptune is the
farthest planet
from the Sun
● It's also the
fourth-largest
object by
diameter
● Mercury is the
closest planet to
the Sun
● This planet's
name has nothing
to do with the
liquid metal
● Venus is the
second planet
from the Sun
● It’s a terribly hot
planet and its
atmosphere is
poisonous
Tuberculosis infographics
Mars
Mars is a cold place full
of iron oxide dust
Venus
Venus is the second
planet from the Sun
Sun
It is the star at the center
of the Solar System
Mercury
Mercury is the closest
planet to the Sun
Saturn
Saturn is a gas giant with
several rings
Jupiter
Jupiter is the fifth planet
from the Sun and
Earth
Earth is the third planet
from the Sun
Neptune
Neptune is the farthest
planet of them all
1 2
3 4
5 6
7 8
Tuberculosis infographics
Mercury is the closest
planet from the sun Mercury
Saturn is a gas giant
with several rings Saturn
Mars is a cold place
full of iron oxide dust Mars
Jupiter is biggest
planet of them all Jupiter
Neptune is the farthest
planet of them all Neptune
20%
40%
60%
80%
100%
1
2
3
4
5
Tuberculosis infographics
Tuberculosis prevention
Jupiter
Jupiter is a gas giant and
the biggest planet
A
Mercury
Mercury is the closest
planet to the Sun
B
Mars
Despite being red, Mars is
actually a cold place
C
Venus
Venus is the second planet
from the Sun
D
Neptune
Neptune is the farthest
planet of them all
E
Earth
Earth is the third planet
from the Sun
F
Sun
It is the star at the center
of the Solar System
G
Saturn
Saturn is a gas giant with
several rings
H
Tuberculosis infographics
Dos during treatment
Mercury is the closest planet to the Sun
Venus is the second planet from the Sun
Mars is actually a very cold place
Neptune is far away from Earth
Don’ts during treatment
Mars is actually a very cold place
Jupiter is the biggest planet of them all
Neptune is far away from Earth
Mercury is the closest planet to the Sun
Tuberculosis infographics
Venus
Venus has a beautiful name and is the
second planet from the Sun
Mercury
Mercury is the closest planet to the Sun
and the smallest of them all
Jupiter Jupiter is a gas giant and the biggest
planet in the Solar System
Saturn
Saturn is a gas giant and has several
rings. It's composed mostly of hydrogen
Tuberculosis infographics
85%
70%
50%
Venus
Venus has a beautiful name and is
the second planet from the Sun
Mars
Despite being red, Mars is a cold
place. It’s full of iron oxide dust
Mercury
Mercury is the closest planet to the
Sun and the smallest of them all
Tuberculosis infographics
Step 5
Step 1
Mercury
Mercury is the
smallest planet in the
Solar System
Venus
Venus is the second
planet from the Sun
and it is very hot
Mars
Despite being red,
Mars is actually a very
cold place
Jupiter
Jupiter is the biggest
planet and it is a gas
giant as well
Saturn
Saturn is made of
hydrogen and helium.
It is a gas giant
Step 2 Step 4
Step 3
Pulmonary TB and TB outside the lungs
Tuberculosis infographics
Neptune
Neptune is the fourth-largest
planet in the Solar System
Mercury
Mercury is the smallest
planet in the Solar System
Mars
Despite being red,
Mars is actually a cold place
Earth
Earth is the third planet from
the Sun and where we live on
Venus
Venus has a beautiful name,
but it’s terribly hot
Saturn
Saturn is a gas giant and has
several rings
1
4
2
3
6
5
Testing for latent tuberculosis
Tuberculosis infographics
Venus
Venus has a beautiful
name and is the second
planet from the Sun
01
Jupiter
Jupiter is a gas giant and
the biggest planet in the
Solar System
02
Mars
Despite being red, Mars is
actually a cold place. It’s
full of iron oxide dust
03
Mercury
Mercury is the closest
planet to the Sun and the
smallest of them all
04
85%
Tuberculosis infographics
Mars is a very cold
place. It Is full of iron
oxide dust
Mars
Mercury is the closest
planet to the Sun and
the smallest one
Mercury
Neptune is the
farthest planet from
the Sun
Neptune
25%
50%
Tuberculosis infographics
Mercury is the closest
planet to the Sun
Mercury
Despite being red, Mars is
a cold place
Mars
It’s a gas giant and the
biggest planet
Jupiter
Venus is the second
planet from the Sun
Venus
Saturn is the ringed planet.
It’s a gas giant
Saturn
Neptune
Neptune is the farthest
planet to the Sun
Mercury is the closest
planet to the Sun
Mercury
Tuberculosis infographics
Venus
Venus has a beautiful name and is the
second planet from the Sun
1,200
3,400
Mercury is the closest planet to the
Sun and the smallest one
Mercury
Jupiter
Jupiter is a gas giant and the biggest
planet in the entire Solar System
5,600
Saturn
It is a gas giant and has several rings.
It’s composed of hydrogen and helium
7,800

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Tuberculosis.pptx

  • 1. TUBERCULOSIS Medicina Interna III Integrantes: Gabriela Santos Aylin Fong Emely
  • 2. DEFINICIÓN Es una enfermedad infecto contagiosa, transmisible, curable, usualmente crónica, de presentación clínica variable, producidas por micobacterias del complejo Micobacterium tuberculosis que puede causar incapacidad de por vida o la muerte.
  • 3. ETIOLOGIA  Las micobacterias pertenecen a la familia Mycobacteriaceae y al orden Actinomycetales: ● MYCOBACTERIUM TUBERCULOSIS ● Es el mas frecuente en el hombre (95 a 99%) ● Su pared celular esta constituida por lípidos ac. grasos α-alquilicos y βhidroxilicos. ● Se tiñe con ZN(carbolfucina) y con AR.
  • 4.
  • 5. Micobacterium tuberculosis Características • Bacilo aerobio fino, ácido-alcohol resistente. • No esporógeno. • Mide de 0,5 por 3 μm. por 3 μm.
  • 6. EPIDEMIOLOGIA • La OMS calcula que en 2016 ocurrieron alrededor de 10.4 millones (intervalo, 8.8 a 12.2 millones) de nuevos casos de TB en todo el mundo, 95% de los cuales ocurrió en países en vías de desarrollo en el continente asiático (6.5 millones), Africa (2.6 millones), el Medio Oriente (0.77 millones) y Latinoamérica (0.26 millones) • Durante los últimos años se han reducido las cifras de casos informados, y se ha iniciado su reducción o estabilización en naciones industrializadas.
  • 7. DE LA EXPOSICIÓN A LA INFECCIÓN 01 02 03 04 M. tuberculosis se transmite casi siempre desde un paciente con TB pulmonar contagiosa a otras personas por medio de las gotitas respiratorias que la tos, el estornudo o la fonación convierten en un aerosol. Estas gotas diminutas se secan pronto; las menores (<5 a 10 μm de diámetro) pueden permanecer suspendidas en el aire durante horas y alcanzar las vías respiratorias terminales al ser inhaladas. Con cada golpe de tos se pueden expulsar nada menos que 3000 gotitas contagiosas. Uno de los factores más importantes para la transmisión de los bacilos tuberculosos es el hacinamiento en espacios mal ventilados, porque se intensifica el contacto con el enfermo.
  • 8. DE LA INFECCIÓN A LA ENFERMEDAD Cuando la infección se adquiere en etapas avanzadas de la vida, es mayor la probabilidad de que el sistema inmunitario maduro contenga la infección, al menos en forma temporal. La enfermedad clínica que se desarrolla poco después de la infección se clasifica como tuberculosis primaria. A B F E D C El riesgo de enfermar después de infectarse depende ante todo de factores endógenos. Sin embargo, el bacilo inactivo puede persistir por años antes de reactivarse y producir tuberculosis secundaria (o posprimaria) El factor de riesgo más importante es sin duda la infección simultánea por VIH, que suprime la inmunidad celular. El riesgo de que una infección latente por M. tuberculosis se convierta en un proceso activo depende directamente del grado de inmunodepresión del paciente.
  • 9. Tuberculosis infographics 60 % 100 % 50 % 75 % Mercury is the closest planet from the sun Mercury 1 Despite being red, Mars is actually a cold place Mars 2 Saturn is a gas giant and has several rings Saturn 3 Neptune is the farthest planet from the Sun Neptune 4
  • 10. Tuberculosis infographics Saturn Venus Mars Mercury is the smallest planet Venus Venus is the second planet from the Sun Mars is full of iron oxide dust and a cold place Saturn is a gas giant and has several rings Mars Jupiter is the biggest planet of them all Neptune is the farthest planet from the Sun Mercury is the closest planet to the Sun Treatment for tuberculosis
  • 11. Tuberculosis infographics Mercury Mercury is the smallest planet 01 Venus Venus is the second planet from the Sun 02 Mars Mars is actually a very cold place 03 Jupiter Jupiter is the biggest planet 04 Venus Venus has a beautiful name 05 Neptune Neptune is very far from the Earth 06
  • 12. Tuberculosis infographics Jupiter Jupiter is the biggest planet of them all 5% Neptune Neptune is the farthest planet from the Sun 15% Mercury Mercury is the smallest planet of them all 30% Saturn Saturn is a gas giant and has several rings 50% Venus Venus is the second planet from the Sun 85% The symptoms of tuberculosis
  • 13. 1 2 3 Tuberculosis infographics Mercury Mercury is the closest planet to the Sun and the smallest of them all Mars Despite being red, Mars is actually a cold place. It’s full of iron oxide dust Jupiter Jupiter is a gas giant and the biggest planet in the Solar System
  • 14. Tuberculosis infographics 3 1 5 4 2 Mercury Mercury is the smallest planet Venus Venus is the second planet from the Sun Mars Mars is actually a very cold place Jupiter Jupiter is the biggest planet of them all Saturn Saturn is made of hydrogen and helium Several tests are used to diagnose tuberculosis
  • 15. Tuberculosis infographics Mercury is the closest planet to the Sun Mercury 01 Venus Venus is the second planet from the Sun 02 Jupiter Jupiter is the biggest planet of them all 03 Neptune Neptune is the farthest planet from the Sun 04 Saturn Saturn is a gas giant and has several rings 05 3 2 1 4 5
  • 16. Tuberculosis infographics 50% Saturn Saturn is a gas giant and has several rings 60% Jupiter Jupiter is the biggest planet of them all 70% Neptune Neptune is the farthest planet from the Sun 40% Earth Earth is the third planet from the Sun
  • 17. Tuberculosis infographics Mercury is the closest planet to the Sun and the smallest one. The planet’s name has nothing to do with the liquid metal 60% Mercury Venus has a beautiful name and is the second planet. It’s terribly hot, even hotter than Mercury. It’s the second-brightest natural object 85% Venus
  • 18. Tuberculosis infographics 55% 01 Venus has a beautiful name and is the second planet from the Sun. It’s terribly hot Venus 90% 02 Mercury is the closest planet to the Sun and the smallest one in the Solar System Mercury Who is the most susceptible to tuberculosis?
  • 19. Tuberculosis infographics Saturn Saturn is a gas giant and has several rings 01 Venus Venus is the second planet from the Sun 02 Neptune Neptune is the farthest planet from the Sun 03 Earth Earth is the third planet from the Sun 04 What causes tuberculosis?
  • 20. Tuberculosis infographics Mars Despite being red, Mars is a cold place. It’s full of iron oxide dust Mercury Mercury is the closest planet to the Sun and the smallest of them all Venus Venus has a beautiful name and is the second planet from the Sun Jupiter Jupiter is a gas giant and the biggest planet in the Solar System
  • 21. Tuberculosis infographics Mars Mars is actually a very cold place Venus Venus has a very beautiful name Saturn It's a gas giant with several rings Mercury It’s the closest planet to the Sun Follow the link in the graph to modify its data and then paste the new one here. For more info, click here Mercury It is the smallest planet of them all 90% 80% 20% 40% 65% Countries with high TB rates
  • 22. Tuberculosis infographics Jupiter Saturn Neptune Mercury Venus ● Jupiter is the biggest planet of them all ● It was named after the Roman god of the skies and lightning ● Saturn is a gas giant and has several rings ● It's composed mostly of hydrogen and helium ● Neptune is the farthest planet from the Sun ● It's also the fourth-largest object by diameter ● Mercury is the closest planet to the Sun ● This planet's name has nothing to do with the liquid metal ● Venus is the second planet from the Sun ● It’s a terribly hot planet and its atmosphere is poisonous
  • 23. Tuberculosis infographics Mars Mars is a cold place full of iron oxide dust Venus Venus is the second planet from the Sun Sun It is the star at the center of the Solar System Mercury Mercury is the closest planet to the Sun Saturn Saturn is a gas giant with several rings Jupiter Jupiter is the fifth planet from the Sun and Earth Earth is the third planet from the Sun Neptune Neptune is the farthest planet of them all 1 2 3 4 5 6 7 8
  • 24. Tuberculosis infographics Mercury is the closest planet from the sun Mercury Saturn is a gas giant with several rings Saturn Mars is a cold place full of iron oxide dust Mars Jupiter is biggest planet of them all Jupiter Neptune is the farthest planet of them all Neptune 20% 40% 60% 80% 100% 1 2 3 4 5
  • 25. Tuberculosis infographics Tuberculosis prevention Jupiter Jupiter is a gas giant and the biggest planet A Mercury Mercury is the closest planet to the Sun B Mars Despite being red, Mars is actually a cold place C Venus Venus is the second planet from the Sun D Neptune Neptune is the farthest planet of them all E Earth Earth is the third planet from the Sun F Sun It is the star at the center of the Solar System G Saturn Saturn is a gas giant with several rings H
  • 26. Tuberculosis infographics Dos during treatment Mercury is the closest planet to the Sun Venus is the second planet from the Sun Mars is actually a very cold place Neptune is far away from Earth Don’ts during treatment Mars is actually a very cold place Jupiter is the biggest planet of them all Neptune is far away from Earth Mercury is the closest planet to the Sun
  • 27. Tuberculosis infographics Venus Venus has a beautiful name and is the second planet from the Sun Mercury Mercury is the closest planet to the Sun and the smallest of them all Jupiter Jupiter is a gas giant and the biggest planet in the Solar System Saturn Saturn is a gas giant and has several rings. It's composed mostly of hydrogen
  • 28. Tuberculosis infographics 85% 70% 50% Venus Venus has a beautiful name and is the second planet from the Sun Mars Despite being red, Mars is a cold place. It’s full of iron oxide dust Mercury Mercury is the closest planet to the Sun and the smallest of them all
  • 29. Tuberculosis infographics Step 5 Step 1 Mercury Mercury is the smallest planet in the Solar System Venus Venus is the second planet from the Sun and it is very hot Mars Despite being red, Mars is actually a very cold place Jupiter Jupiter is the biggest planet and it is a gas giant as well Saturn Saturn is made of hydrogen and helium. It is a gas giant Step 2 Step 4 Step 3 Pulmonary TB and TB outside the lungs
  • 30. Tuberculosis infographics Neptune Neptune is the fourth-largest planet in the Solar System Mercury Mercury is the smallest planet in the Solar System Mars Despite being red, Mars is actually a cold place Earth Earth is the third planet from the Sun and where we live on Venus Venus has a beautiful name, but it’s terribly hot Saturn Saturn is a gas giant and has several rings 1 4 2 3 6 5 Testing for latent tuberculosis
  • 31. Tuberculosis infographics Venus Venus has a beautiful name and is the second planet from the Sun 01 Jupiter Jupiter is a gas giant and the biggest planet in the Solar System 02 Mars Despite being red, Mars is actually a cold place. It’s full of iron oxide dust 03 Mercury Mercury is the closest planet to the Sun and the smallest of them all 04
  • 32. 85% Tuberculosis infographics Mars is a very cold place. It Is full of iron oxide dust Mars Mercury is the closest planet to the Sun and the smallest one Mercury Neptune is the farthest planet from the Sun Neptune 25% 50%
  • 33. Tuberculosis infographics Mercury is the closest planet to the Sun Mercury Despite being red, Mars is a cold place Mars It’s a gas giant and the biggest planet Jupiter Venus is the second planet from the Sun Venus Saturn is the ringed planet. It’s a gas giant Saturn Neptune Neptune is the farthest planet to the Sun Mercury is the closest planet to the Sun Mercury
  • 34. Tuberculosis infographics Venus Venus has a beautiful name and is the second planet from the Sun 1,200 3,400 Mercury is the closest planet to the Sun and the smallest one Mercury Jupiter Jupiter is a gas giant and the biggest planet in the entire Solar System 5,600 Saturn It is a gas giant and has several rings. It’s composed of hydrogen and helium 7,800

Editor's Notes

  1. La tuberculosis (TB), una de las enfermedades más antiguas que ha afectado a seres humanos y que tal vez existió desde las épocas de los prehomínidos, es una causa importante de muerte a nivel mundial. Por lo general, la enfermedad afecta los pulmones, aunque hasta en un tercio de los casos hay compromiso de otros órganos. Sin tratamiento 50 a 65% de los enfermos puede morir en un plazo de 5 años. El contagio suele ocurrir por vía aérea, a través de las gotitas que expulsan los pacientes con TB contagiosa
  2. del complejo de M. tuberculosis, que comprenden ocho distintos grupos, el agente más importante y frecuente de enfermedad en seres humanos es M. tuberculosis
  3. M. tuberculosis es una bacteria aerobia fina, no formadora de esporas, bacilar, que mide 0.5 por 3 μm.
  4. las cifras de casos informados de TB se incrementaron en los países industrializados. Estos incrementos estuvieron relacionados en gran medida con la inmigración desde países con alta prevalencia de TB; infección con VIH; problemas sociales como incremento de la pobreza urbana, número de indigentes y consumidores de drogas, así como la desaparición de los servicios para atención de la TB.
  5. Las demás vías de contagio del bacilo tuberculoso, como la piel o la placenta, son raras y no tienen significación epidemiológica El riesgo de transmisión y adquisición subsiguiente de infección por M. tuberculosis depende sobre todo de factores exógenos. Las probabilidades de entrar en contacto con un caso de TB, la duración e intimidad de ese contacto, el grado de contagiosidad y el ambiente que se comparte con la persona enferma son, todos ellos, factores importantes para la probabilidad de transmisión.
  6. El riesgo de enfermar después de infectarse depende sobre todo de factores endógenos, como las defensas innatas inmunológicas y no inmunológicas y la eficacia funcional de la inmunidad celular. La enfermedad clínica que se desarrolla poco después de la infección se clasifica como tuberculosis primaria y es común en niños en los primeros años de vida y en individuos inmunodeprimidos Esta puede ser grave y diseminada, pero por lo general no se asocia con alta contagiosidad. que, a causa de la formación frecuente de cavitación, es más infecciosa que la enfermedad primaria, El riesgo es mucho más elevado en personas infectadas con VIH. La reinfección de un individuo previamente infectado, que es común en áreas con altas tasas de TB, también puede favorecer el desarrollo de la enfermedad