Bone ossification types: Intramembranous and Endochondral ossification

1. FSC204A61:
FORENSIC
ANTHROPOLOGY
Dr. Suchita Rawat (MSc, MPhil, PhD)

2. Bone hierarchical structure
Fig. 1. Bone hierarchical structure. The V, IV, and III levels construct the mechanical support structure for
bone tissues, and the II and I levels construct the microenvironment for the bone tissue cells.
HAP: hydroxyapatite; GAGs: glycosaminoglycans; NCPs: non-collagenous proteins (osteocalcin,
osteonectin, osteopontin, adhesion proteins and proteoglycans)
The main component of the ECM is
collagen fibers (85–90%), which are
periodically arranged by collagen fibrils
with a diameter of approximately 35–60
nm and a length of 1 μm.

3. BONE FORMATION
Key terms: Osteogenesis, ossification,
calcification, osteoid (from osteoblast)
8 weeks

5. BONE FORMATION
Fig. 3.
Embryonic bone
development.
a)Intramembran
ous bone
formation
b)Endochondral
ossification.

6. This Photo by Unknown Author is licensed under CC BY-SA