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GASTRIC OUTLET OBSTRUCTION
AND
ITS SURGICAL MANAGEMENT
DEFINITION
• Gastric Outlet Obstruction is clinical or
pathophysiological consequence of any
disease process that produces mechanical
impediment to gastric emptying
Gastric Outlet Obstruction
Etiology
BENIGN
• Peptic Ulcer disease
• Ingestion of Caustics
• Trichobezoars ( Hairballs)
• Adult hypertrophic Pyloric stenosis
• Pyloric mucosal diaphragm
• Pancreatic Pseudocysts
• BARIATRIC PROCEDURES
• Vertical banded gastroplasty
• Roux-en-Y gastric bypass
ETIOLOGY
• MALIGNANT
• Carcinoma of Stomach
• Periampullary carcinomas
Carcinoma Head of pancreas
ampullary carcinoma
Carcinoma of second part of duodenum
cholangiocarcinomas
PRESENTATION
• HISTORY
Epigastric or left hyochondrial pain
> which is most common feature in peptic ulcer disease
vomiting
>unpleasant smell
> copious amounts
>projectile
>NON BILIOUS
>contains undigested food particles taken hours to
several days ago
History
• Feeling of unwell
• Anorexia
• Nausea
• Early satiety
• Weight loss
• Abdominal swelling
EXamination
• GENERAL PHYSICAL EXAMINATION
• Chronically ill looking patient
• Wasted
• Dehydrated
• Pale
• Left supraclavicular lymphadenopathy (with
malignant obstruction)
Examination
• ABDOMINAL
• Distended stomach ( fullness in epigastrium)
• Visible Gastric Peristalisis
• Succussion splash
• Hepatosplenomegally
• Look for Ascities ( sign of Carcinoma spread)
Epigastric fullness
Succussion splash
• Sloshing sound heard through stethoscope
place over epigastrium during sudden
movement of the patient
.
CLINICAL FEATURES
METABOLIC EFFECTS
• Vomiting of Hydochloric acid ( HCL) leads to
hypochloremic metabolic alkalosis
• Kidneys respond by excreting Bicarbonate and
conserving chloride
• This bicarbonate is excreted with sodium
• So with time patient becomes more
profoundly dehydrated and hyponatremic
Metabolic effects
• Because of dehydration body responds to
preserve intravascular volume by sodium
retention
• Now potassium and hydrogen are excreted in
preference to preserve sodium
• This leads to paradoxical aciduria ( acidic urine
despite metabolic alkalosis)
• Hypokalemia ensues
Metabolic effects
• Alkalosis leads to lowering of circulating
ionised calcium
• This can lead to tetany
INVESTIGATIONS
CBC
S/E
LFT
Test for H pylori
Investigations
• ABG s : Metabolic Alkalosis
• Urine C/E: paradoxical aciduria
Radiology
• Plane Xray Erect Abdomen:
Large Gastric shadow and Large amount of
Gastric fluid
Plane Xray Abdomen
Barium Meal
• 6 hour peroid of fasting is observed prior to
study
• Barium sulphate is ingested by the patient
• Xray images are taken at 20 to 30 minutes
interval in supine position
Barium meal
Upper GI endoscopy
visualize Gastric Outlet
Biopsy
Gastric outlet obstruction
CT scan
• For extraluminal obstruction
• Periampullary carcinomas
Management
• Two Aims
1.Correct metabolic abnormality
2.Deal with mechanical obstruction
Correcting Metabolic Abnormalities
• Pass double large Bore IV line
• Pass wide bore nasogastric tube to empty the
stomach
• Sometimes an orogastric tube is required to
lavage and empty the stomach as nasogastric
tube may not be sufficiently large to deal with
contents of the stomach
Correcting metabolic abnormalities
• Intravenous Normal Saline (0.9% NaCI) with
Potassium Supplementation
• Correct anemia
management
• Early cases may settle with conservative
management
• NPO
• ANTACIDS
• PPI
• as the edema around the ulcer diminishes as
the ulcer is healed
Surgery for benign GOO
Pyloroplasty with vagotomy
Truncal Vagotomy and Antrectomy and
Billroth Reconstructions
PYLOROPLASTY
• FINEY
• JABOULEYS
• Heineke-Mikulicz
GASTROJEJUNOSTOMY
BALLOON DIALATATION
• ENDOSCOPIC DALATION
• Repeated dilatations needed
• May cause perforation
Endoscopic stenting for unresectable
tumor
stenting

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