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R. Hubert Cyril Lourdes 
3rd M.B.B.S., 
MADHA MEDICAL COLLEGE & RESEARCH INSTITUTE
DEVELOPMENT 
OF 
NOSE
Five facial prominences 
1. FRONTONASAL prominence 
2. MAXILLARY prominence 
3. MEDIAL NASAL prominence 
4. LATERAL NASAL prominence 
5. MANDIBULAR prominence
 Appearance of NASAL PLACODES at the end of 4th 
week of IUL 
 Appears lateral to the FRONTONASAL prominence 
as a LOCAL THICKENING of SURFACE ECTODERM. 
 NASAL PITS are formed on 5th week of IUL, by 
invagination of NASAL PLACODES. 
 NASAL PROMINENCE are formed following the 
formation of NASAL PITS 
NASAL PROMINENCE divided into 2 subdivisions: 
1. LATERAL nasal prominence 
2. MEDIAL nasal prominence
Following 2 weeks after 5th week of IUL, maxillary 
prominence continue to INCREASE IN SIZE. 
Simultaneously, they grow medially, compressing 
the medial nasal prominence towards the midline. 
In the formation of upper lip LATERAL NASAL 
PROMINENCE is not involved 
The deep furrow which separates maxillary 
prominence and later nasal prominence is called as 
NASOLACRIMAL GROOVE. 
Nasolacrimal groove forms NASOLACRIMAL DUCT 
and its upper wider end forms the LACRIMAL SAC.
Development of lateral wall 
of nose 
 During 8th week of IUL 6 to 7 ridges appear 
on the lateral nasal wall, those ridges are 
called as ETHAMO TURBINALS.
 1st ETHAMO TURBINAL 
1. ASCENDING portion forms AGGER NASI 
2. DESCENDING portion forms UNCINATE 
PROCESS 
 2nd ETHAMO TURBINAL forms MIDDLE 
TURBINATE. 
 3rd ETHAMO TURBINAL forms SUPERIOR 
TURBINATE 
 4th and 5th ETHAMO TURBINAL forms 
SUPREME TURBINATE 
 MAXILLO TURBINAL forms INFERIOR 
TURBINATE
 FURROWS between each ETHAMO TURBINALS 
forms respective NASAL MEATUSES 
 1st FURROW :- MIDDLE MEATUS (b/w 1st & 
2nd ET) 
 2nd FURROW :- SUPERIOR MEATUS 
 3rd FURROW :- SUPREME MEATUS 
 4th FURROW :- INFERIOR MEATUS
DEVELOPMENTAL ANOMALIES 
OF 
NOSE
 PROBOSIS DEFORMITY 
 ARHINIA (Nasal aplasia) 
 POLYRHINIA (Double nose) 
 CHOANAL ATRESIA 
 NASAL DERMOID CYST 
 NASAL GLIOMAS 
 NASAL HEMANGIOMA (vascular 
hamartoma)
 NASAL MASS 
1. CYSTIC MASS 
• MENINGOCOELE 
• MENINGOENCEPHALOCOEL 
2. SOLID MASS 
 GLIOMA 
 CRANIOPHARYNGIOMA 
 CLEFT LIP and PALATE 
1. MEDIAN NASAL CLEFT 
2. MEDIAL NASAL CLEFT 
3. LATERAL NASAL CLEFT
ARHINIA
Development 
of 
paranasal air sinuses
Paranasal sinuses develop as OUTPOUCHING from 
mucous membrane of lateral wall of nose. 
Maxillary sinus and Ethmoidal sinuses are present 
at birth 
Growth of sinuses continues during childhood and 
early adult life 
Radiologically various sinuses can be identified at 
various milestones of growth. They are: 
I. Maxillary sinus – 4th to 5th month 
II. Ethmoidal sinus – 1 year 
III. Sphenoidal sinus – 4 years 
IV. Frontal sinus – 6 years.
DEVELOPMENTAL ANOMALIES 
OF 
paranasal air sinuses
Unilateral maxillary air sinus aplasia 
Total paranasal sinus aplasia
Unilateral 
maxillary sinus 
aplasia
Unilateral maxillary 
sinus aplasia
Total aplasia of 
paranasal sinuses
Total aplasia of 
paranasal sinuses
Development of Nose and Sinuses

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Development of Nose and Sinuses

  • 1. R. Hubert Cyril Lourdes 3rd M.B.B.S., MADHA MEDICAL COLLEGE & RESEARCH INSTITUTE
  • 3. Five facial prominences 1. FRONTONASAL prominence 2. MAXILLARY prominence 3. MEDIAL NASAL prominence 4. LATERAL NASAL prominence 5. MANDIBULAR prominence
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  • 6.  Appearance of NASAL PLACODES at the end of 4th week of IUL  Appears lateral to the FRONTONASAL prominence as a LOCAL THICKENING of SURFACE ECTODERM.  NASAL PITS are formed on 5th week of IUL, by invagination of NASAL PLACODES.  NASAL PROMINENCE are formed following the formation of NASAL PITS NASAL PROMINENCE divided into 2 subdivisions: 1. LATERAL nasal prominence 2. MEDIAL nasal prominence
  • 7. Following 2 weeks after 5th week of IUL, maxillary prominence continue to INCREASE IN SIZE. Simultaneously, they grow medially, compressing the medial nasal prominence towards the midline. In the formation of upper lip LATERAL NASAL PROMINENCE is not involved The deep furrow which separates maxillary prominence and later nasal prominence is called as NASOLACRIMAL GROOVE. Nasolacrimal groove forms NASOLACRIMAL DUCT and its upper wider end forms the LACRIMAL SAC.
  • 8. Development of lateral wall of nose  During 8th week of IUL 6 to 7 ridges appear on the lateral nasal wall, those ridges are called as ETHAMO TURBINALS.
  • 9.  1st ETHAMO TURBINAL 1. ASCENDING portion forms AGGER NASI 2. DESCENDING portion forms UNCINATE PROCESS  2nd ETHAMO TURBINAL forms MIDDLE TURBINATE.  3rd ETHAMO TURBINAL forms SUPERIOR TURBINATE  4th and 5th ETHAMO TURBINAL forms SUPREME TURBINATE  MAXILLO TURBINAL forms INFERIOR TURBINATE
  • 10.  FURROWS between each ETHAMO TURBINALS forms respective NASAL MEATUSES  1st FURROW :- MIDDLE MEATUS (b/w 1st & 2nd ET)  2nd FURROW :- SUPERIOR MEATUS  3rd FURROW :- SUPREME MEATUS  4th FURROW :- INFERIOR MEATUS
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  • 13.  PROBOSIS DEFORMITY  ARHINIA (Nasal aplasia)  POLYRHINIA (Double nose)  CHOANAL ATRESIA  NASAL DERMOID CYST  NASAL GLIOMAS  NASAL HEMANGIOMA (vascular hamartoma)
  • 14.  NASAL MASS 1. CYSTIC MASS • MENINGOCOELE • MENINGOENCEPHALOCOEL 2. SOLID MASS  GLIOMA  CRANIOPHARYNGIOMA  CLEFT LIP and PALATE 1. MEDIAN NASAL CLEFT 2. MEDIAL NASAL CLEFT 3. LATERAL NASAL CLEFT
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  • 26. Paranasal sinuses develop as OUTPOUCHING from mucous membrane of lateral wall of nose. Maxillary sinus and Ethmoidal sinuses are present at birth Growth of sinuses continues during childhood and early adult life Radiologically various sinuses can be identified at various milestones of growth. They are: I. Maxillary sinus – 4th to 5th month II. Ethmoidal sinus – 1 year III. Sphenoidal sinus – 4 years IV. Frontal sinus – 6 years.
  • 27. DEVELOPMENTAL ANOMALIES OF paranasal air sinuses
  • 28. Unilateral maxillary air sinus aplasia Total paranasal sinus aplasia
  • 31. Total aplasia of paranasal sinuses
  • 32. Total aplasia of paranasal sinuses