3. What is a Trigeminal Neuralgia ?
Defined by - International Association for the Study of Pain (ISAP)
•“ A sudden and usually unilateral severe brief stabbing , recurrent pain in the
distribution of one or more branches of the fifth cranial nerve.”
•It is an excruciating, short-lasting (<2 minutes), unilateral facial pain that may be
spontaneous or triggered by gentle, innocuous stimuli and separated by pain-
free intervals of varying duration
4. Why trigeminal neuralgia is important
• One of the most excruciating, agonising pains
• Recurrent episodes
• Disturbs the quality of life significantly
• Often wrongly diagnosed as pain of “dental origin” and patient may end up
with teeth extraction before the actual diagnosis is made
• Can cause severe psychological disturbances, patients may even develop
suicidal tendencies
5. Epidemiology
• Incidence - 4.3 per 100,000
• Female > male ( male preponderance in Indian studies)
• Right side > Left side ( 3:2)
• Mostly unilateral (95%)
• Bilateral (5%) ----- 18% in pts with MS (multiple sclerosis)
8. VASCULAR COMPRESSION
1. Superior Cerebellar A.
2. AICA
3. Serpentine Basilar A.
4. PICA.
5. Large pontine branches of Basilar A.
6. Combination of the above.
1. Superior Petrosal V.
2. Transverse Pontine V.
3. V. of Cerebellopontine fissure.
4. V. of Middle Cerebellar Peduncle.
5. Common stem of veins draining the lateral
part of cerebellar hemisphere.
ARTERIAL VENOUS
MIXED - ARTERIAL AND VENOUS
12. Not all facial pains are trigeminal neuralgias
Taking a good history
13.
14. Atypical Trigeminal Neuralgia – TN 2
• Pain is aching, throbbing or burning for more than 50% of the time
and there is constant background pain but strictly confined to the
anatomical distribution of the trigeminal divisions.
• Can be multiple neurovascular conflicts
16. • Normal neurological examination
• May be decreased sensation over involving area
• Absent corneal sensation – suspect CP angle tumor
• Hypertension (Neurogenic HTN )
• d/t Vascular compression over vagal REZ / ventrolateral medulla
• After MVD surgery reports of disappearance of hypertension
17. TN- on contralateral side of CP angle tumor due to
1. Brian stem distortion
2. Arachnoiditis
3. Contralateral vascular cross compression
** INSPITE OF PRESENCE OF CP ANGLE MASS – ACTUAL VASCULAR COMPRESSION CAN BE
A CAUSE OF TN. In such cases ONLY TUMOR EXCSION WILL Not RELIEVE PAIN . MVD is
REQUIRED
23. Management of TN
1. Management of severe pain – crisis in ER
2. Medical Management
3. Surgical Management
a) Percutaneous procedures
b) Microvascular Decompression (MVD)
4. Stereotactic radiosurgery
24. Management of acute crisis in ER
• NSAIDS and Opiates usually do not work
• No best medication yet in acute episode
• i.v infusion of Fosphenytoin – useful in some pateints ( needs ECG
monitoring)
• Local 8% spray of lidocaine
27. Psychological support
• The fear, loneliness, and depression associated with TN may require
psychological, social, or other nonmedical help.
• Support groups can help to reduce feelings of isolation and despair
and can also provide high-quality information
30. Percutaneous procedures are NOT first choice
Indications
1. Failed medical therapy
2. Unfit for MVD
3. Elderly > 65 years age
4. Previously failed MVD
5. TN – secondary to MS, Pontine infarction, Brain stem white matter
lesions
34. Radiosurgery
• Ablate the cisternal part of the trigeminal nerve with gamma knife
radiosurgery
• Linear accelerator based radiosurgery seems to be nearly as effective
• Takes time to show response – ( 4 weeks to 6 months)
• Recurrence rates are upto 25 %
• Radiosurgery may be indicated after a failed MVD or other measures
43. Our Results
• Total no of cases: 35
• Duration : May 2014 to till date
• Follow up: No recurrence
• Complications : paradoxical csf rhinnorhea -1, improved