In a cross between female flies expressing three X-linked recessive traits (scute bristles, sable body, and vermillion eyes) and wild-type males, all F1 generation females were wild-type while males expressed all three mutations. Analysis of over 1000 F2 generation offspring found deviations from expected numbers of double crossovers, suggesting the genes are arranged in a specific order along the X chromosome with some interference between crossovers.
Seal of Good Local Governance (SGLG) 2024Final.pptx
2- In Drosophila- a cross was made between females - all expressing th.docx
1. 2. In Drosophila, a cross was made between females - all expressing the three X -linked recessive
traits scute bristles (sc), sable body (s), and vermillion eyes (v) - and wile type males (P
generation). In the F 1 , all femaleswere wild type, while all the males expressed all three mutant
traits. The cross was carried to the F 2 generation, and 1000 offspring were counted, with the
results shown in the following table. No determination of sex was made in the data. ( 8 points)
(a) What are the genotypes of both the male and female parents in both the P and F 1
generations? (b) Determine the sequence of the three genes and the map distances between them.
(c) Are there more or fewer double crossovers than expected? (d) Calculate the coefficient of
coincidence. Does it represent positive or negative interference?