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Platform for Tissue Engineering and 3D Printing at La Paz University Hospital. presentation
- 1. Tissue Engineering & 3D Printing Platform Daniel Cermeno. Laboratory Manager Contact: piti3D@idipaz.es Phone: +34 625 30 13 12
- 2. Contents
- 3. Motivation
- 4. The Tissue Engineering and 3D Printing Platform purpose is to promote the development of research and solutions based on tissue engineering and bioprinting Offers services of Design, Computer Imaging, Virtual Planning, and 3D Printing Main areas of activity: • Tissue and Organ Bioprinting. • Lab-on-a-chip (LOC) and Organ-on-a-chip devices (OOC). • Tissue engineering-based organ and tissue modeling. • Development of Medical Devices (Biomodels, Surgical guides, Prothesis and Implants) by 3D printing. • Virtual computer imaging-aided technical assistance for surgery planning. Objectives
- 5. Contents
- 6. 3D Printing Traditional manufacturing is based on subtraction techniques 3D Printing is based on the addition of materials layer-by-layer allowing to produce complex forms with mesh structures (scaffolds).
- 7. Main Advantages • Perfect implant fit • Possibility to print a mesh structure for better bone attachment • Fantastic aesthetic and reconstructive results • Reduced surgery time and faster recovery • Best way to maintain/restore a patient’s quality of life • Reduced treatment cost and shorter hospitalization • Less blood loss • Reduced time under anesthesia
- 8. Contents
- 11. Virtual Planning for Neurosurgery Cranyosinostosis is a condition in which one or more craneal sutures close prematurely, impeding the normal development of the brain and changing the normal bone grow pattern. As a result patient that suffer from this condition have large bone defects.
- 12. Surgical Guides for Craneosinostosis Virtual Planning for Neurosurgery
- 13. Virtual Planning for Neurosurgery
- 14. CMF Reconstruction and Simulation
- 15. Biomodels
- 16. Contents
- 17. RM 3DPTI Bioprinting Biological Implants Transition Regenerative medicine (RM) is the branch of the medicine that aims at finding solutions to regenerate damaged tissues. Tissue engineering (TE) is the use of a combination of cells, engineering and materials methods, and suitable signaling factors to improve or replace biological functions.
- 18. Bioprinting Cell-laden hydrogel Growth Factors Scaffold Print 3D multi component parts with different materials with a customized external shape and an internal mesh structure that mimic human living tissues.
- 19. Bioprinting
- 20. Contents
- 21. 3DnoLOC Colon Organoids Project Corneal Regeneration with 3DP Skin 3D Printing for Epidermolysis Bullosa On going Projects at the Platform
- 22. Success Keys in the Platform • Strong basic science focused on applied projects oriented to solve real problems of patients and clinicians. • State-of-the-art technologies (3DP, Bioprinting…). • Big emphasis on promotion. • Collaboration between public and private entities. • Solid Financial Plans • Cohesive team with members from different institutions and disciplines (Biologists, and Engineers).
- 23. Next Steps Development of projects in the short term: • Guides for complex reconstructions. • Biomodels. • ATM Custom Made. • Cartilage bioprinting. • Anatomical implants. Financial Resources: • RETOS • CDTI • H2020 • Otros
- 24. We are looking for… • New problems to solve with our technologies. • Participation in consortium projects, and financial applications. • University agreements for master thesis, and senior students. • Promotional activities, and participation in congresses in the field. • Development of new technologies and applications. • Generate Intellectual Property, and Technology Transfer. • Increase our team with new professionals.
- 25. Team Dr. Ramón Cantero Director Dra. María Paz de Miguel Scientific Advisor José Manuel Baena Scientific Coordinator Daniel Cermeño Lab Manager Juan José Pérez Blanco Investigator
- 26. Thanks for your attention Daniel Cermeno