Easy Kit (proton pump inhibitor, clarithromycin, and amoxicillin, or an imidazole) is the first-line treatment for Helicobacter pylori infection. However, the effectiveness of triple therapy is decreasing due to the increase in antibiotic resistance. Triple therapy for H pylori infection remains an option for first-line therapy in areas of low (< 15%) clarithromycin resistance and consists of the following: Proton pump inhibitor (PPI) (eg, omeprazole 20 mg BID, lansoprazole 30 mg BID, esomeprazole 40 mg QD, pantoprazole 40 mg QD, rabeprazole 20 mg BID) [2, 5] plus.