The MemTrax team has been researching and developing innovative ways to investigate and measure the human brain. Our vast network of talent has led the Alzheimer's disease and dementia research community for years. The most well funded researchers in the world use MemTrax because it is simple, fun, and reliable. he idea that being proactive and preventative about your cognition and brain health is critical for a long happy life. By using our free online memory test users are able to take a quick interactive cognitive test and watch their results on special graphs and charts we have developed. MemTrax is a family founded business created to motivate and inspire people in taking a proactive and preventative approach to caring for their brain health. Our mission is to continue to develop innovative cognitive assessments that are fun and repeatable while advancing research to better understand the human brain Please reach out if you might have any questions.

1. Digital Cognitive Testing to Improve Healthcare
Measuring and monitoring Brain Health for early detection and data analysis

2. A thermometer for the Brain
How does the doctor currently measure your
cognition or memory when visiting for an
annual checkup?
A physician charges $100 to take your
temperature, a MemTrax test could be more
lucrative with similar common use application.
Billing for our cognitive test has several
options: From codes 92507 to 97130 there
are several options for execution.
● Critical for early treatment while
most effective
● Indicates earliest possible signs of
memory loss
● Tests the type of memory most
commonly associated with AD /
Dementia
● Repeatable on a regular basis - Fun
Early Detection is Critical

3. Research Support
Dr. Mike Weiner
Principal Investigator of ADNI
largest study in the world
concerning Alzheimer's Disease
Directed funds since 2004 - $120
million federal (NIA), $98 million
industry
Created the Brain Health Registry
featuring MemTrax
Researching for over 50 years and
passionate about open data sharing
http://adni.loni.usc.edu/about/
Charles J. Fuschillo, Jr.
President & Chief Executive Officer
of the Alzheimer’s Foundation of
America
New York State Senator for nearly 16
years
AFA created memory screening
efforts into a year-round National
Memory Screening Program that
provides free, confidential memory
screenings to individuals across the
country and is using MemTrax
https://alzfdn.org/team_member/charl
es-j-fuschillo-jr/
Dr. Frederick Schmitt
Professor of Neurology,
Neurosurgery, Psychiatry,
Behavioral Science, and
Psychology
The University of Kentucky
Sanders-Brown Center on
Aging - Clinical Studies uses
MemTrax
Mary Carter Award recipient
for his work with patients
with neurodegenerative
disease
https://ukhealthcare.uky.edu/
doctors/frederick-schmitt
Dr. Babak Kateb
Founding Chairman of the Board of
Society for Brain Mapping and
Therapeutics and The Brain Mapping
Foundation
Director of Brain Technology and
Innovation Park
Associate Editor for The Journal of
Alzheimer’s Disease
https://www.worldbrainmapping.org/A
bout/Babak-Kateb

4. Decentralized Clinical Trials
Combining specific variables associated with
cognition in conjunction with Machine
Learning components to discover new
understanding of the Human Brain.
Big data analysis with AI is the most logical
path forward to breakthroughs in the field.
● Since the beginning of the
COVID-19 pandemic there has been
an increase in demand for remote
testing
● Long term adaptation for more
efficient research, Longitudinal
● On site trials are expensive and time
consuming limiting the number of
participants
● More appealing to Pharma and
Biotech companies
Demand for Remote Assessment

5. MemTrax Scientific Advisory Board
J. Wesson Ashford M.D.,
Ph.D.
Authored over 160 publications
on Alzheimer’s disease and 10
demonstrating the effectiveness
of MemTrax
Department of Psychiatry &
Behavioral Sciences, Stanford
University
Director, War-Related Illness and
Injury Study Center at the Palo
Alto campus of the VA Palo Alto
Dr. Michael Bergeron
Artificial Intelligence and
Machine Learning Research
Clinical & Scientific Advisor
Sport Sciences & Medicine,
WTA Women's Tennis
Senior Vice President of
Development & Applications
of SIVOTEC Analytics
American College of Sports
Medicine (ACSM) – Fellow
Dr. Xianbo Zhou
Pharmaceutical Executive at
SJN Biomed
27 years research
experience in Biochem
General Manager of SJN
Biomed
Professor and Founding
Director of the Center for
Alzheimer’s Disease
Research at Washington
Institute of Clinical Research
George Perry M.D., Ph.D.
Editor and Chief of The Journal of
Alzheimer’s Disease
Determining the sequence of
events leading to neuronal
oxidative damage
University Chair in Neurobiology at
The University of Texas at San
Antonio
Dr. Frank Tarpin-Bernard
Founder and shareholder of the
Scientific Brain Training
company, France
Professor in Computer Science
at the National Institute of
Applied Science of Lyon
Published numerous
peer-reviewed journal articles
and book chapters

6. Demand is Increasing for Brain Health Programs
Expected dramatic increase in the number of people with dementia worldwide
Source: Alzheimer’s Disease International, World Alzheimer Report

7. Associated Care Costs Will Rise Proportionately
Currently Alzheimer’s Disease is the 3rd most expensive disease in the US
Source: Alzheimer’s Association, Changing the Trajectory of Alzheimer’s Disease: How Treatment by 2025 Saves Lives and Dollars
$
226
B
$
1.1
T

8. FDA approves first
Alzheimer’s disease drug
Aduhelm
(Aducanumab-avwa)
Biogen Pharmaceutical
“In clinical trials, ADUHELM reduced amyloid beta
plaques by 59 to 71 percent at 18 months of treatment”
● Establish Baseline Scores
● Regular Scheduled Testing
● Identify Changes Early
● Determine Memory and Cognitive
changes from Drugs or Diseases
including COVID-19
Drug Efficiency Testing

9. • Empowering everyone's brain health
• Simple translatable format
• Providing telehealth brain assessment
• Easy accessibility for
underrepresented populations
• Measuring brain treatment outcomes
• Lowering risk from brain-related issues
MemTrax Delivers a Better Brain Assessment
Creating new opportunities for a global community

10. Current tests have limited ability for
individuals, healthcare providers and
researchers to precisely measure &
monitor memory
Problems we Solve
• Large practice effects over time
• Lack precision of analysis
• Require trained experts to administer
• Require special equipment/environment
• Time intensive (for rater and subject)
• Not tech or mobile friendly
• Limited, or no ability to customize
New Brain Assessments are Needed

11. Accessible and Easy Brain Health Monitoring
Driving toward a world with better brain health treatment
Open Repeatable
Engaging
Quick Inclusive
Customizable
Available on all devices
Only takes about 2
minutes per session
Easy and intuitive for
everyone to use
Accurate long-term
performance tracking
Millions of unique test
permutations
Adjustable for clinicians
& researchers

12. How the MemTrax Assessment Works
User navigates to
test
Test downloaded
client-side from server
User starts test
(3s count down)
Instructions presented
User recognizes repeat
pictures & responds
Results sent back to server
(displaying results optional)

13. The MemTrax Test in Action

14. MemTrax Board of Advisors
Curtis Ashford
Managing member
MemTrax LLC
Produced MemTrax
self scoring design
Connecting people
around the world to
better understand
the Human Brain
Chris Outwater
CEO Liberty Access
Innovative device
development
Early adoption of
MemTrax
Nick Larson
General Partner at
Driven Capital
Social Media
Networking and
Marketing
Investor Relations
Lee S. Manela
MemTrax Developer
eCommerce and
CMS based web-site
Master
Manages multiple
$1M+ revenue sites
Robby McCullough
GoDaddy Partnership
Co-Founder of Beaver
Builder for Wordpress
Startup success
achieved | Over 40
active employees
Franklin Lowe
Healthcare Account
Director
MBA in Marketing
HIPAA certification
10 years healthcare
marketing with
senior populations
Pete Martinez
IBM Vice President of
Global Business
Services | 32 Years
Research at MIT Mass.
Institute of Technology
Big Data Analytics
CEO of SIVOTEC
Bioinformatics
https://www.linkedin.c
om/in/pete-martinez-4
803174/
https://www.linkedin.
com/in/franklinlowe/
https://www.linkedin.
com/in/lee-manela-0
6895118/
https://www.linkedin.
com/in/nlarson1/
https://www.linkedin.
com/in/chris-outwate
r-96115a2/
https://www.linkedin.
com/in/memtrax/
https://www.linkedin.
com/in/robmcculloug
h/

15. A Sample of Our Data
UCSF Brain Health Registry data, includes >10,000 participants

16. Other
• CANS-MCI
• CAMCOG / CANTAB
• CAMCI
• CogState
• CST (Computerized Self Test)
• IN/WN (IntegNeuro/WebNeuro)
• Mindstreams (NeuroTrax)
• MC-CARE
• Staying Sharp (AARP)
Computerized cognitive tests
• Easier to administer––established
model of self-administration
• Works across platforms
• Faster to administer
• More precise in measurement of
episodic memory
• Better ability to track memory
performance over time
MemTrax Advantage
Easy, quick, and longitudinal

17. Continued Innovation for Measuring Brain Health
Assessments to
measure more brain
health domains
MemTrax Roadmap
PRO
Professional version
for healthcare &
research administration
Advanced user
analytics & AI
retracement modeling
of AD
Native apps for
iOS & Android
(Completed 9/21)

18. Sports concussion
Alcohol or drug abuse
Medication change
Mood / Depression
Sleep
Age
Dementia
Alzheimer’s disease
Long COVID-19
Vehicle accident
Combat concussion
Poor diet
Lack of exercise
Loud noises
Smoking
Isolation
Consider All Brain Changing Events
Use cases for MemTrax

19. Partnerships Advancing Research and Availability

20. Publications and Research Inclusions
• Bredeson D. E. (2014). Reversal of cognitive decline: A novel therapeutic
program. Aging. 6(9): 707-717.
• Martin, Rose, et al. (2011). Reliability of Online MemTrax Digital Photo
Recognition, Word Recognition and H-Scan Screening Tests. Poster
presentation at the Alzheimer's Researchers' Symposium, Stanford
University.
• Ashford J. W., Gere E., & Bayley P. J. (2011). Measuring Memory in Group
Settings Using a Continuous Recognition Test. Journals of Alzheimer's
Disease. 27(4): 885-895.
• Ashford, J. W., et al. "P3-106: Screening for memory problems in a large
group setting." Alzheimer's & Dementia 4.4 (2008): T549-T550.
• Ashford, J. "MemTrax (Computerized Memory Screen)." American
Association for Geriatric Psychiatry Annual Meeting. New Orleans, LA, USA.
2007.
• Belden, Christine M., et al. "P3-108: Subjective memory complaints in the
healthy elderly." Alzheimer's & Dementia 4.4 (2008): T550-T551.
Published Works
• Bergeron MF, et al. (2020) Utility of MemTrax and Machine Learning Modeling in
Classification of Mild Cognitive Impairment. JAD;77(4):1545
• Weiner MW, et al. (2018) The Brain Health Registry: An internet-based platform for
recruitment, assessment, and longitudinal monitoring of participants for
neuroscience studies. Alzheimer’s Dement.Aug;14(8):1063-1076
• Ashford JW, et al. (2019)The MemTrax Test Compared to the Montreal Cognitive
Assessment Estimation of Mild Cognitive Impairment.
• Bergeron MF, et al. (2019)Episodic-Memory Performance in Machine Learning
Modeling for Predicting COgnitive Health Status Classification. JAD70(1):277-286
• Zhou X, et al. (2019) Advances in screening instruments for Alzheimer’s disease.
Aging Med.May 31;2(2):88-93
• Liu X, et al. (2021) Validity of the MemTrax Memory Test compared to the Montreal
Cognitive Assessment in the Detection of Mild Cognitive Impairment and Dementia
due to Alzheimer’s Disease in a Chinese Cohort. JAD80(3):1257-1267
• Weiner MW, et al. (2019) Cognitive Performance in Parkinson’s Disease in the
Brian Health Registry. JAD68(3):1029-1038
• Ashford CB, et al. (2019) A Computerized Continuous-Recognition Task for
Measurement of Episodic Memory. JAD69(2):385-399

21. Publications and Research Inclusions
• UCSF Brain Health Registry includes MemTrax in cognitive testing battery along with self-report data
(>100K participants)
• Alzheimer’s Foundation of America using MemTrax at https://afamemorytest.com/
• University of Wageningen (Netherlands) testing against MoCA for examining the role of nutrients in
cognition
• University of Kentucky, Sanders Brown Center on Aging
• Analyzing MemTrax data from over 2,000 individuals to norm across age bands, gender and education
levels
Ongoing Studies

22. Thank You
URL: https://memtrax.com/
Twitter: @MemTrax
Email: Curtis@MemTrax.com
Cell: (415)722-0219